Page last updated: 2024-08-23

mifepristone and org 31710

mifepristone has been researched along with org 31710 in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (35.00)18.2507
2000's8 (40.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhakta, A; Kloosterboer, HJ; Mizutani, T; Moudgil, VK1
de Gooyer, ME; Deckers, GH; Dijkema, R; Kloosterboer, HJ; Orlemans, EO; Schoonen, WG1
Deckers, GH; Kloosterboer, HJ; Schoonen, WG1
Joosten, JW; Kloosterboer, HJ; Schoonen, WG1
Cornish, AL; Lee, CS; Musgrove, EA; Sutherland, RL; Swarbrick, A1
Koper, JW; Lamberts, SW; Molijn, GJ; Stigter, E; van Uffelen, CJ1
Dinda, S; Herman, M; Hurd, C; Iwasaki, K; Kloosterboer, HJ; Moudgil, VK; Underwood, B1
Bellido, C; de Jong, FH; Sánchez-Criado, JE; Tébar, M1
Andersson, M; Billig, H; Markström, E; Shao, R; Svensson, EC1
Billig, H; Friberg, PA; Johansson, M; Markström, E; Shao, R1
Billig, H; Carlsson, B; Carlsson, LM; Friberg, PA; Larsson, DG; Nielsen, ECh; Rung, E; Shao, R; Svensson, PA1
Billig, H; Egecioglu, E; Fernandez-Rodriguez, J; Friberg, A; Ljungström, K; Rung, E; Shao, R; Wang, X; Weijdegård, B; Zhu, C; Zhu, Y1
Bergh, C; Billig, H; Friberg, PA; Rung, E1
Billig, H; Egecioglu, E; Fernandez-Rodriguez, J; Ling, C; Ljungström, K; Shao, R; Weijdegård, B1
Billig, H; Friberg, PA; Larsson, DG1
Goyeneche, AA; Seidel, EE; Telleria, CM1
Bennett, PR; Brosens, JJ; Chen, L; Georgiou, EX; Johnson, MR; Khanjani, S; Lei, K; Sooranna, SR1
Gamarra-Luques, CD; Goyeneche, AA; Hapon, MB; Telleria, CM1
Chen, LC; Hsu, SP; Huo, YN; Kuo, CT; Lee, WS; Wen, HC; Yang, HC1
Basar, M; Bozkurt, I; Buchwalder, L; Guzel, E; Kayisli, U; Lockwood, CJ; Ocak, N; Schatz, F1

Other Studies

20 other study(ies) available for mifepristone and org 31710

ArticleYear
Novel antiprogestins Org 31806 and 31710: interaction with mammalian progesterone receptor and DNA binding of antisteroid receptor complexes.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 42, Issue:7

    Topics: Animals; Cattle; Chickens; Cytosol; DNA; Estrenes; Female; Furans; Kinetics; Mifepristone; Progesterone; Progestins; Promegestone; Receptors, Progesterone; Species Specificity; Uterus

1992
Pharmacological properties of a new selective antiprogestagen: Org 33628.
    Annals of the New York Academy of Sciences, 1995, Jun-12, Volume: 761

    Topics: Adrenal Glands; Animals; Cell Line; Estrenes; Female; Furans; Gonanes; Guinea Pigs; Humans; In Vitro Techniques; Mifepristone; Ovulation; Pregnancy; Progestins; Receptors, Cell Surface; Receptors, Progesterone; Structure-Activity Relationship

1995
Pharmacology of two new very selective antiprogestagens: Org 31710 and Org 31806.
    Human reproduction (Oxford, England), 1994, Volume: 9 Suppl 1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Abortifacient Agents, Steroidal; Abortion, Induced; Androgen Antagonists; Animals; Estrenes; Female; Furans; Gonanes; Macaca; Male; Mammary Neoplasms, Experimental; Menstruation-Inducing Agents; Mifepristone; Pregnancy; Progestins; Rats; Receptors, Glucocorticoid; Receptors, Progesterone

1994
Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4

    Topics: Breast Neoplasms; Carcinoma; Cell Division; Desogestrel; Dose-Response Relationship, Drug; Estradiol; Estrenes; Estrogen Antagonists; Female; Furans; Humans; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Nandrolone; Norethindrone; Norpregnenes; Pregnanes; Pregnenediones; Progesterone; Promegestone; Tumor Cells, Cultured

1995
Antiprogestin inhibition of cell cycle progression in T-47D breast cancer cells is accompanied by induction of the cyclin-dependent kinase inhibitor p21.
    Molecular endocrinology (Baltimore, Md.), 1997, Volume: 11, Issue:1

    Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Drug Resistance; Estrenes; Furans; Hormone Antagonists; Humans; Mifepristone; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Oncogene Proteins; Phosphorylation; Progestins; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Retinoblastoma Protein; Tumor Cells, Cultured

1997
Antiprogestins and iatrogenic glucocorticoid resistance.
    Life sciences, 1997, Volume: 60, Issue:9

    Topics: Binding, Competitive; Dexamethasone; Drug Resistance; Estrenes; Furans; Glucocorticoids; Gonanes; Hormone Antagonists; Humans; Hydrocortisone; In Vitro Techniques; Lymphocyte Activation; Meningeal Neoplasms; Meningioma; Mifepristone; Progestins; Receptors, Glucocorticoid

1997
Characterization of ligand binding, DNA binding and phosphorylation of progesterone receptor by two novel progesterone receptor antagonist ligands.
    Molecular and cellular biochemistry, 1997, Volume: 175, Issue:1-2

    Topics: Binding, Competitive; Blotting, Western; DNA; Electrophoresis, Polyacrylamide Gel; Estrenes; Furans; Gonanes; Hormone Antagonists; Humans; Ligands; Mifepristone; Phosphorylation; Progesterone Congeners; Promegestone; Receptors, Progesterone; Sodium Dodecyl Sulfate; Tumor Cells, Cultured

1997
Comparison of the effects of antiprogestins RU38486, ZK98299 and ORG31710 on periovulatory hypophysial, ovarian and adrenal hormone secretion in the rat.
    Journal of endocrinological investigation, 2000, Volume: 23, Issue:3

    Topics: Adrenal Glands; Animals; Corticosterone; Estrenes; Female; Follicle Stimulating Hormone; Furans; Gonanes; Hormone Antagonists; Inhibins; Luteinizing Hormone; Mifepristone; Ovary; Ovulation; Pituitary Gland, Posterior; Progesterone; Rats; Rats, Wistar

2000
Progesterone receptor antagonists Org 31710 and RU 486 increase apoptosis in human periovulatory granulosa cells.
    Fertility and sterility, 2001, Volume: 76, Issue:6

    Topics: Caspase 3; Caspases; Dexamethasone; Dihydrotestosterone; DNA Fragmentation; Electrophoresis, Agar Gel; Estrenes; Female; Furans; GABA Antagonists; Glucocorticoids; Granulosa Cells; Hormone Antagonists; Humans; Mifepristone; Nucleosomes; Picrotoxin; Progesterone; Receptors, GABA-A; Receptors, Progesterone; Spectrometry, Fluorescence

2001
Expression of progesterone receptor (PR) A and B isoforms in mouse granulosa cells: stage-dependent PR-mediated regulation of apoptosis and cell proliferation.
    Biology of reproduction, 2003, Volume: 68, Issue:3

    Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Division; Chorionic Gonadotropin; Estrenes; Female; Furans; Granulosa Cells; Hormone Antagonists; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mifepristone; Ovarian Follicle; Proliferating Cell Nuclear Antigen; Protein Isoforms; Random Allocation; Receptors, Progesterone

2003
Progesterone-receptor antagonists and statins decrease de novo cholesterol synthesis and increase apoptosis in rat and human periovulatory granulosa cells in vitro.
    Biology of reproduction, 2005, Volume: 72, Issue:3

    Topics: Animals; Apoptosis; Cell Survival; Cholesterol; Estrenes; Female; Furans; Gene Expression Profiling; Gene Expression Regulation; Granulosa Cells; Hormone Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Mifepristone; Oligonucleotide Array Sequence Analysis; Ovulation; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Signal Transduction

2005
Nuclear progesterone receptor A and B isoforms in mouse fallopian tube and uterus: implications for expression, regulation, and cellular function.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:1

    Topics: Animals; Apoptosis; Blotting, Western; Chorionic Gonadotropin; Epidermal Growth Factor; ErbB Receptors; Estradiol; Estrenes; Fallopian Tubes; Female; Furans; Gene Expression Regulation; Hormone Antagonists; Horses; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mifepristone; Organ Size; Progesterone; Receptors, Progesterone; Uterus

2006
Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells.
    Molecular reproduction and development, 2006, Volume: 73, Issue:10

    Topics: Apoptosis; Cells, Cultured; Cholesterol; Diterpenes; Estrenes; Farnesol; Farnesyltranstransferase; Female; Furans; Granulosa Cells; Hormone Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Leucine; Mifepristone; Ovulation; Protein Prenylation; Quinolones; Receptors, Progesterone

2006
Developmental and hormonal regulation of progesterone receptor A-form expression in female mouse lung in vivo: interaction with glucocorticoid receptors.
    The Journal of endocrinology, 2006, Volume: 190, Issue:3

    Topics: Animals; Blotting, Western; Dexamethasone; Estrenes; Female; Furans; Gene Expression Regulation, Developmental; Glucocorticoids; Immunohistochemistry; Immunoprecipitation; Lung; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Mifepristone; Progesterone; Protein Isoforms; Receptors, Glucocorticoid; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2006
Dominant role of nuclear progesterone receptor in the control of rat periovulatory granulosa cell apoptosis.
    Biology of reproduction, 2009, Volume: 80, Issue:6

    Topics: Animals; Antibodies, Blocking; Apoptosis; Cyanoketone; Dose-Response Relationship, Drug; Estrenes; Female; Furans; Granulosa Cells; Membrane Proteins; Mifepristone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Progesterone

2009
Growth inhibition induced by antiprogestins RU-38486, ORG-31710, and CDB-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2.
    Investigational new drugs, 2012, Volume: 30, Issue:3

    Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cytostatic Agents; DNA Fragmentation; Estrenes; Female; Furans; Hormone Antagonists; Humans; Mifepristone; Norpregnadienes; Ovarian Neoplasms

2012
Progesterone acts via the nuclear glucocorticoid receptor to suppress IL-1β-induced COX-2 expression in human term myometrial cells.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Cell Nucleus; Cells, Cultured; Cyclooxygenase 2; Estrenes; Female; Furans; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Gene Silencing; Genes, Reporter; Humans; Interleukin-1beta; Mifepristone; Myometrium; NF-kappa B; Progesterone; Receptors, Glucocorticoid; Receptors, Progesterone; RNA, Small Interfering; Transcription Factor RelA

2012
Resistance to cisplatin and paclitaxel does not affect the sensitivity of human ovarian cancer cells to antiprogestin-induced cytotoxicity.
    Journal of ovarian research, 2014, Volume: 7

    Topics: Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Estrenes; Female; Furans; Hormone Antagonists; Humans; Inhibitory Concentration 50; Mifepristone; Norpregnadienes; Paclitaxel

2014
Progesterone receptor-NFκB complex formation is required for progesterone-induced NFκB nuclear translocation and binding onto the p53 promoter.
    Endocrinology, 2015, Volume: 156, Issue:1

    Topics: Active Transport, Cell Nucleus; Butadienes; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Estrenes; Flavonoids; Furans; Gene Expression Regulation; Hormone Antagonists; Humans; Mifepristone; NF-kappa B; Nitriles; Progesterone; Promoter Regions, Genetic; Protein Binding; Receptors, Progesterone; Sulfones; Tumor Suppressor Protein p53

2015
Effects of tibolone and its metabolites on prolactin and insulin-like growth factor binding protein-1 expression in human endometrial stromal cells.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2015, Volume: 31, Issue:5

    Topics: Blotting, Western; Contraceptive Agents, Female; Dexamethasone; Endometrium; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrenes; Estrogen Receptor Modulators; Estrogens; Female; Furans; Glucocorticoids; Hormone Antagonists; Humans; Insulin-Like Growth Factor Binding Protein 1; Medroxyprogesterone Acetate; Mifepristone; Norpregnanes; Norpregnenes; Prolactin; Real-Time Polymerase Chain Reaction; RNA, Messenger; Stromal Cells

2015