Page last updated: 2024-08-23

mifepristone and naloxone

mifepristone has been researched along with naloxone in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's12 (41.38)18.2507
2000's6 (20.69)29.6817
2010's10 (34.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
De Kloet, ER; Eijgelshoven, MH; Van den Berg, DT; Van Giersbergen, PL1
Armario, A; Garvey, JS; Giralt, M; Hidalgo, J1
Calignano, A; Capasso, A; Persico, P; Sorrentino, L1
Bopp, BL; Fossum, G; Lobo, RA; Mishell, DR; Shoupe, D; Spitz, IM1
Chatterton, RT; Fox, SR; Smith, MS1
Deis, RP; Soaje, M2
Capasso, A; Di Giannuario, A; Loizzo, A; Pieretti, S; Sagratella, S; Sorrentino, L1
Benowitz, NL; Heller, PH; Levine, JD; Miao, FJ1
Carón, RW; Deis, RP; Salicioni, AM2
Almeida, OF; Deicke, J; Fischer, D; Gärtner, P; Hassan, AH; Hellbach, S1
Levine, JD; Miao, FJ1
Antonijevic, IA; Bicknell, RJ; Douglas, AJ; Leng, G; Russell, JA1
de Di Nasso, EG; Deis, RP; Soaje, M1
Fournier, NM; Galic, MA; Martin, LJ1
Lam, S; McNally, GP1
Bregonzio, C; Deis, RP; Penissi, A; Soaje, M; Valdez, S1
Deis, R; Ezquer, M; Gabutti, CV; Maldonado, C; Soaje, M1
Cao, J; Dong, Z; Han, H; Xu, L1
Hajhashemi, V; Minaiyan, M; Movahedian, A; Sadeghi, H; Talebi, A1
Hidalgo, JM; Laorden, ML; Milanés, MV; Navarro-Zaragoza, J1
Bregonzio, C; de Di Nasso, EG; Gamboa, DF; Pennacchio, GE; Soaje, M; Valdez, SR1
Laorden, ML; Milanés, MV; Navarro-Zaragoza, J1
Jahn, GA; Pennacchio, GE; Soaje, M; Villegas-Gabutti, C1
Jahn, GA; Pennacchio, GE; Soaje, M; Villegas-Gabutti, CM; Vivas, L1

Reviews

1 review(s) available for mifepristone and naloxone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

28 other study(ies) available for mifepristone and naloxone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Activation of glucocorticoid receptors and the effect of naloxone during hemorrhagic hypotension.
    European journal of pharmacology, 1991, Nov-26, Volume: 205, Issue:2

    Topics: Adrenalectomy; Animals; Corticosterone; Drug Interactions; Hemodynamics; Male; Mifepristone; Naloxone; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Shock, Hemorrhagic

1991
Effect of morphine administration on rat liver metallothionein and zinc metabolism.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1

    Topics: Animals; Immobilization; Injections, Subcutaneous; Liver; Male; Metallothionein; Mifepristone; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Zinc

1991
The action of dexamethasone on electrically-induced contractions of guinea-pig isolated ileum.
    General pharmacology, 1991, Volume: 22, Issue:2

    Topics: Animals; Cycloheximide; Dactinomycin; Dexamethasone; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mifepristone; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Receptors, Glucocorticoid

1991
Antiprogestin treatment decreases midluteal luteinizing hormone pulse amplitude and primarily exerts a pituitary inhibition.
    American journal of obstetrics and gynecology, 1990, Volume: 163, Issue:6 Pt 1

    Topics: Adult; Analysis of Variance; Depression, Chemical; Female; Humans; Hydrocortisone; Luteal Phase; Luteinizing Hormone; Mifepristone; Naloxone; Pituitary Gland; Progesterone

1990
Role of proestrous progesterone secretion in suppressing basal pulsatile LH secretion during estrus of the estrous cycle.
    Neuroendocrinology, 1989, Volume: 50, Issue:3

    Topics: Animals; Estrus; Female; Immunization, Passive; Luteinizing Hormone; Mifepristone; Naloxone; Pentobarbital; Periodicity; Proestrus; Progesterone; Rats; Rats, Inbred Strains

1989
A modulatory role of endogenous opioids on prolactin secretion at the end of pregnancy in the rat.
    The Journal of endocrinology, 1994, Volume: 140, Issue:1

    Topics: Animals; Bromocriptine; Endorphins; Female; Gestational Age; Mifepristone; Naloxone; Oxymorphone; Pregnancy; Pregnancy, Animal; Proestrus; Progesterone; Prolactin; Rats; Rats, Wistar

1994
Dexamethasone selective inhibition of acute opioid physical dependence in isolated tissues.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cycloheximide; Dexamethasone; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Mifepristone; Muscle Contraction; Naloxone; Opioid-Related Disorders; Pyrrolidines; Rabbits; Substance Withdrawal Syndrome

1996
Contribution of adrenal hormones to nicotine-induced inhibition of synovial plasma extravasation in the rat.
    British journal of pharmacology, 1997, Volume: 120, Issue:2

    Topics: Adrenal Glands; Animals; Bradykinin; Capillary Permeability; Male; Mecamylamine; Mifepristone; Naloxone; Nicotine; Platelet Activating Factor; Propanolamines; Rats; Rats, Sprague-Dawley

1997
Participation of both adrenergic and opioidergic systems in the negative feedback of adrenal progesterone on LH secretion.
    European journal of pharmacology, 1997, Aug-13, Volume: 332, Issue:3

    Topics: Adrenal Glands; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Estradiol; Feedback; Female; Hormone Antagonists; Idazoxan; Luteinizing Hormone; Metoprolol; Mifepristone; Naloxone; Ovariectomy; Prazosin; Progesterone; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Opioid

1997
Opioidergic regulation of prolactin secretion during pregnancy: role of ovarian hormones.
    The Journal of endocrinology, 1997, Volume: 155, Issue:1

    Topics: Animals; Estradiol; Estrogen Antagonists; Female; Gestational Age; Hormone Antagonists; Mifepristone; Naloxone; Narcotic Antagonists; Opioid Peptides; Pregnancy; Progesterone; Prolactin; Rats; Rats, Wistar; Tamoxifen

1997
Regulation of prolactin secretion by adrenal steroids in oestrogen-treated ovariectomized rats: participation of endogenous opioid peptides.
    Neuropharmacology, 1997, Volume: 36, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Estradiol; Female; Hormone Antagonists; Hydrocortisone; Mifepristone; Naloxone; Opioid Peptides; Ovariectomy; Progesterone; Prolactin; Rats; Rats, Wistar

1997
Inherent glucocorticoid response potential of isolated hypothalamic neuroendocrine neurons.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:2

    Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine Vasopressin; beta-Endorphin; Calcium; Cells, Cultured; Coculture Techniques; Corticotropin-Releasing Hormone; Culture Media, Serum-Free; Dexamethasone; Glucocorticoids; Kinetics; Male; Mifepristone; Morphine; Naloxone; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Sodium; Tetrodotoxin; Verapamil; Veratridine

1998
Neural and endocrine mechanisms mediating noxious stimulus-induced inhibition of bradykinin plasma extravasation in the rat.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bradykinin; Capsaicin; Electric Stimulation; Endocrine Glands; Hypophysectomy; Knee Joint; Male; Mifepristone; Naloxone; Narcotic Antagonists; Nervous System Physiological Phenomena; Neurons, Afferent; Pain; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sympathetic Nervous System; Synovial Fluid

1999
Effect of progesterone on the activation of neurones of the supraoptic nucleus during parturition.
    Journal of reproduction and fertility, 2000, Volume: 120, Issue:2

    Topics: Analysis of Variance; Animals; Depression, Chemical; Female; Gene Expression; Genes, fos; Hormone Antagonists; Immunohistochemistry; Labor, Obstetric; Mifepristone; Naloxone; Narcotic Antagonists; Neurons; Oxytocin; Pregnancy; Progesterone; Rats; Rats, Sprague-Dawley; Supraoptic Nucleus

2000
Regulation by endogenous opioids of suckling-induced prolactin secretion in pregnant and lactating rats: role of ovarian steroids.
    The Journal of endocrinology, 2002, Volume: 172, Issue:2

    Topics: Animals; Estrogen Antagonists; Female; Hormone Antagonists; Lactation; Maternal Behavior; Mifepristone; Naloxone; Narcotic Antagonists; Pregnancy; Progesterone; Prolactin; Rats; Rats, Wistar; Tamoxifen

2002
Alpha2-adrenergic inhibition prevents the accompanied anticonvulsant effect of swim stress on behavioral convulsions induced by lithium and pilocarpine.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Lithium; Male; Mifepristone; Naloxone; Pilocarpine; Rats; Rats, Wistar; Seizures; Stress, Physiological; Swimming; Yohimbine

2004
Altered vulnerability to acute opiate withdrawal following stress: roles of N-methyl-D-aspartate and glucocorticoid receptors.
    Behavioral neuroscience, 2005, Volume: 119, Issue:5

    Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hormone Antagonists; Male; Mifepristone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Stress, Physiological; Time Factors

2005
Dopaminergic mechanisms involved in prolactin release after mifepristone and naloxone treatment during late pregnancy in the rat.
    Neuroendocrinology, 2006, Volume: 84, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Enzyme Inhibitors; Female; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Hormone Antagonists; Hydrazines; Hypothalamus; Mifepristone; Naloxone; Narcotic Antagonists; Pregnancy; Pregnancy, Animal; Prolactin; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase

2006
Pituitary changes involved in prolactin secretion induced by mifepristone and naloxone during late pregnancy.
    Neuroendocrinology, 2009, Volume: 89, Issue:2

    Topics: Animals; Female; Lactotrophs; Mifepristone; Naloxone; Pituitary Gland; Pregnancy; Prolactin; Rats; Rats, Wistar; RNA, Messenger; Time Factors

2009
Opioid withdrawal for 4 days prevents synaptic depression induced by low dose of morphine or naloxone in rat hippocampal CA1 area in vivo.
    Hippocampus, 2010, Volume: 20, Issue:2

    Topics: Analgesics, Opioid; Animals; CA1 Region, Hippocampal; Excitatory Postsynaptic Potentials; Male; Mifepristone; Morphine; Naloxone; Narcotic Antagonists; Neuronal Plasticity; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Substance Withdrawal Syndrome; Synapses; Synaptic Transmission; Time Factors

2010
Central and peripheral anti-inflammatory effects of maprotiline on carrageenan-induced paw edema in rats.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2010, Volume: 59, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Antidepressive Agents, Second-Generation; Carrageenan; Edema; Hormone Antagonists; Indomethacin; Injections, Spinal; Male; Maprotiline; Mifepristone; Naloxone; Narcotic Antagonists; Prazosin; Propranolol; Rats; Rats, Wistar; Yohimbine

2010
Glucocorticoid receptors participate in the opiate withdrawal-induced stimulation of rats NTS noradrenergic activity and in the somatic signs of morphine withdrawal.
    British journal of pharmacology, 2012, Volume: 166, Issue:7

    Topics: Animals; Hormone Antagonists; Male; Mifepristone; Morphine Dependence; Naloxone; Narcotic Antagonists; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Solitary Nucleus; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase

2012
Opioid modulation of prolactin secretion induced by stress during late pregnancy. Role of ovarian steroids.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:3

    Topics: Analgesics, Opioid; Animals; Estradiol; Female; Mifepristone; Naloxone; Naltrexone; Narcotic Antagonists; Ovary; Pregnancy; Progesterone; Prolactin; Rats; Rats, Wistar; Steroids; Tamoxifen

2014
Glucocorticoid receptor but not mineralocorticoid receptor mediates the activation of ERK pathway and CREB during morphine withdrawal.
    Addiction biology, 2017, Volume: 22, Issue:2

    Topics: Analgesics, Opioid; Animals; Cyclic AMP Response Element-Binding Protein; Dopamine; Hormone Antagonists; Male; MAP Kinase Signaling System; Mifepristone; Mineralocorticoid Receptor Antagonists; Morphine; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase

2017
Role of Estradiol in the Regulation of Prolactin Secretion During Late Pregnancy.
    Neurochemical research, 2016, Volume: 41, Issue:12

    Topics: Animals; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Hypothalamus, Middle; Mifepristone; Naloxone; Pregnancy; Pregnancy, Animal; Progesterone; Prolactin; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, Progesterone; Receptors, Prolactin; Tyrosine 3-Monooxygenase

2016
Role of Oxytocin in Prolactin Secretion during Late Pregnancy.
    Neuroendocrinology, 2018, Volume: 106, Issue:4

    Topics: Animals; Bodily Secretions; Female; Hormone Antagonists; Lactotrophs; Mifepristone; Naloxone; Narcotic Antagonists; Oxytocin; Pregnancy; Prolactin; Rats; Rats, Wistar

2018