mifepristone has been researched along with morphine in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (30.95) | 18.2507 |
| 2000's | 19 (45.24) | 29.6817 |
| 2010's | 8 (19.05) | 24.3611 |
| 2020's | 2 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Capasso, A; Di Giannuario, A; Loizzo, A; Pieretti, S; Sorrentino, L | 2 |
| Calignano, A; Capasso, A; Persico, P; Sorrentino, L | 2 |
| Armario, A; Garvey, JS; Giralt, M; Hidalgo, J | 1 |
| Bernton, EW; Bryant, HU; Holaday, JW; Kenner, JR | 1 |
| Couch, DB; Sawant, SG | 1 |
| Bayer, BM; Flores, LR; Hernandez, MC | 1 |
| Capasso, A; Cutrufo, C; Di Giannuario, A; Loizzo, A; Palazzesi, S; Pieretti, S; Sorrentino, L | 1 |
| Brown, RD; Fuchs, BA; Harris, LS; Levier, DG; McCay, JA; Munson, AE | 1 |
| Bianchi, M; Maggi, R; Martini, L; Panerai, AE | 1 |
| Almeida, OF; Deicke, J; Fischer, D; Gärtner, P; Hassan, AH; Hellbach, S | 1 |
| Aouizerate, B; Barrot, M; Le Moal, M; Marinelli, M; Piazza, PV | 1 |
| Couch, DB; Kozlowski, RS; Sawant, SG | 1 |
| Capasso, A; d'Emmanuele di Villa Bianca, R; Pinto, A; Sorrentino, R | 1 |
| Capasso, A; Casciano, C; Loizzo, A | 1 |
| Gomez-Flores, R; Liang-Suo, J; Weber, RJ | 1 |
| Lipkowski, AW; Nakamura, F; Takenaka, Y; Toth, G; Usui, H; Yoshikawa, M | 1 |
| Cai, J; Cao, J; Dong, Z; Sui, N; Wang, Y; Xu, L; Yang, Y; Zheng, X | 1 |
| Moynihan, JA; Sheridan, PA | 1 |
| Lim, G; Mao, J; Sung, B; Wang, S; Zeng, Q | 2 |
| Lim, G; Mao, J; Wang, S | 1 |
| Vathy, I; Velísek, L | 1 |
| Lam, S; McNally, GP | 1 |
| Lim, G; Mao, J; Sung, B; Wang, S; Yang, L; Zeng, Q | 1 |
| Cao, J; Dong, Z; Han, H; Mao, R; Xu, L | 1 |
| Cao, J; Dong, Z; Han, H; Hao, W; Wang, M; Xu, L | 1 |
| Hajhashemi, V; Mesripour, A; Rabbani, M | 1 |
| Ghitza, UE; Li, YQ; Lu, L; Wang, XY; Zhao, M | 1 |
| Capasso, A; Loizzo, A | 1 |
| Capasso, A | 1 |
| Cao, J; Dong, Z; Han, H; Xu, L | 1 |
| Fan, YD; Huma, T; Li, L; Ma, YY; Niu, HC; Ren, H; Wang, GM; Xu, LQ; Yu, HL | 1 |
| Attarzadeh-Yazdi, G; Azizi, P; Haghparast, A; Hesam, S; Karimi, S; Yazdi-Ravandi, S | 1 |
| Attarzadeh-Yazdi, G; Azizi, P; Haghparast, A; Hesam, S; Karimi, S; Razavi, Y; Yazdi-Ravandi, S | 1 |
| Laorden, ML; Milanés, MV; Navarro-Zaragoza, J | 1 |
| Haghparast, A; Sarihi, A; Taslimi, Z | 1 |
| Haghparast, A; Hesam, S; Karimi, S; Karimi-Haghighi, S; Razavi, Y | 1 |
| Aikins, JK; Check, D; Check, JH; Poretta, T; Srivastava, MD | 1 |
1 review(s) available for mifepristone and morphine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
41 other study(ies) available for mifepristone and morphine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Central interaction of dexamethasone and RU-38486 on morphine antinociception in mice.
Topics: Animals; Brain; Dexamethasone; Drug Interactions; Injections, Intraventricular; Male; Mice; Mifepristone; Morphine; Pain Measurement | 1992 |
Effect of RU-38486 on dexamethasone reversal of morphine-induced constipation in mice.
Topics: Animals; Constipation; Cycloheximide; Dexamethasone; Gastrointestinal Transit; Injections, Subcutaneous; Male; Mice; Mifepristone; Morphine | 1991 |
The interaction of peripherally and centrally administered dexamethasone and RU 38486 on morphine analgesia in mice.
Topics: Analgesia; Animals; Dexamethasone; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mifepristone; Morphine; Pain; Pain Measurement; Receptors, Glucocorticoid; Sensory Thresholds | 1991 |
Effect of morphine administration on rat liver metallothionein and zinc metabolism.
Topics: Animals; Immobilization; Injections, Subcutaneous; Liver; Male; Metallothionein; Mifepristone; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Zinc | 1991 |
Role of adrenal cortical activation in the immunosuppressive effects of chronic morphine treatment.
Topics: Adrenal Cortex; Adrenalectomy; Animals; Cell Division; Concanavalin A; Corticosterone; Drug Implants; Immunosuppressive Agents; Lipopolysaccharides; Male; Mice; Mice, Inbred C3H; Mifepristone; Morphine; Organ Size; Spleen; Thymus Gland; Time Factors | 1991 |
The action of dexamethasone on electrically-induced contractions of guinea-pig isolated ileum.
Topics: Animals; Cycloheximide; Dactinomycin; Dexamethasone; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mifepristone; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Receptors, Glucocorticoid | 1991 |
The clastogenicity of morphine sulfate in vivo.
Topics: Adrenalectomy; Animals; beta-Endorphin; Cyclophosphamide; DNA Repair; Female; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Micronucleus Tests; Mifepristone; Morphine; Mutagens; Spleen | 1995 |
Acute immunosuppressive effects of morphine: lack of involvement of pituitary and adrenal factors.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Animals; Cell Division; Hypophysectomy; Immunosuppressive Agents; Lymphocytes; Male; Mifepristone; Morphine; Pituitary Hormones; Rats; Rats, Sprague-Dawley | 1994 |
Opioids and corticosteroids involvement in the regulation of the neocortical spindling episodes in DBA/2J mice.
Topics: Adrenal Cortex; Animals; Cerebral Cortex; Corticosterone; Cycloheximide; Dexamethasone; Disease Models, Animal; Disease Susceptibility; Electroencephalography; Epilepsy; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred DBA; Mifepristone; Morphine; Naltrexone | 1993 |
Hepatic and splenic phagocytosis in female B6C3F1 mice implanted with morphine sulfate pellets.
Topics: Animals; Drug Tolerance; Female; Kupffer Cells; Liver; Macrophages; Mice; Mice, Inbred Strains; Mifepristone; Mononuclear Phagocyte System; Morphine; Naltrexone; Organ Size; Phagocytosis; Spleen | 1993 |
RU 486 reduces morphine-induced analgesia in mice, but steroid receptors are not involved.
Topics: Analgesia; Animals; Dexamethasone; Drug Interactions; Injections, Subcutaneous; Male; Mice; Mifepristone; Morphine; Pain Measurement; Progesterone; Receptors, Steroid | 1996 |
Inherent glucocorticoid response potential of isolated hypothalamic neuroendocrine neurons.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine Vasopressin; beta-Endorphin; Calcium; Cells, Cultured; Coculture Techniques; Corticotropin-Releasing Hormone; Culture Media, Serum-Free; Dexamethasone; Glucocorticoids; Kinetics; Male; Mifepristone; Morphine; Naloxone; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Sodium; Tetrodotoxin; Verapamil; Veratridine | 1998 |
Dopamine-dependent responses to morphine depend on glucocorticoid receptors.
Topics: Animals; Dopamine; Hormone Antagonists; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Morphine; Motor Activity; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 1998 |
The role of adrenal corticosteroids in induction of micronuclei by morphine.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Animals; Blood Proteins; Cell Nucleus; Cells, Cultured; Codeine; Corticosterone; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Metyrapone; Mice; Mice, Inbred C57BL; Micronucleus Tests; Mifepristone; Morphine; Spleen | 2001 |
Dexamethasone modulates hypotension induced by opioids in anaesthetised rats.
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Cycloheximide; Dexamethasone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Heart Rate; Hypotension; Male; Mifepristone; Morphine; Narcotics; Oligopeptides; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Opioid, kappa | 2001 |
Dexamethasone reduces morphine-induced Straub reaction in mice.
Topics: Animals; Anti-Inflammatory Agents; Cycloheximide; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Hormone Antagonists; Infusions, Parenteral; Mice; Mifepristone; Morphine; Movement; Narcotics; Protein Synthesis Inhibitors; Receptors, Glucocorticoid; Tail | 2002 |
Immunosuppression induced by central action of morphine is not blocked by mifepristone (RU 486).
Topics: Animals; Brain; Cell Division; Cells, Cultured; Glucocorticoids; Hormone Antagonists; Hypothalamo-Hypophyseal System; Immunosuppressive Agents; Killer Cells, Natural; Male; Mifepristone; Morphine; Periaqueductal Gray; Rats; Rats, Inbred F344; T-Lymphocytes | 2002 |
Anti-analgesic activity of enterostatin (VPDPR) is mediated by corticosterone.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Corticosterone; Dietary Fats; Male; Mice; Mifepristone; Morphine; Oligopeptides; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2003 |
Stress enables synaptic depression in CA1 synapses by acute and chronic morphine: possible mechanisms for corticosterone on opiate addiction.
Topics: Animals; Corticosterone; Drug Administration Schedule; Electric Stimulation; Electrodes, Implanted; Escape Reaction; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Maze Learning; Mifepristone; Morphine; Neuronal Plasticity; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Reaction Time; Stress, Physiological; Synapses | 2004 |
Modulation of the innate immune response to HSV-1 following acute administration of morphine: role of hypothalamo-pituitary-adrenal axis.
Topics: Analysis of Variance; Animals; Cells, Cultured; Central Nervous System Viral Diseases; Corticosterone; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Herpesvirus 1, Human; Hormone Antagonists; Hypothalamo-Hypophyseal System; Immunity, Innate; Interferons; Interleukin-12; Male; Mice; Mice, Inbred BALB C; Mifepristone; Morphine; Narcotics; Pituitary-Adrenal System; Polyethylene Glycols; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spleen; Time Factors | 2005 |
Evidence for a long-term influence on morphine tolerance after previous morphine exposure: role of neuronal glucocorticoid receptors.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mifepristone; Morphine; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Time Factors | 2005 |
Spinal glucocorticoid receptors contribute to the development of morphine tolerance in rats.
Topics: Analgesics, Opioid; Animals; Blotting, Western; Dexamethasone; Dose-Response Relationship, Drug; Drug Implants; Drug Tolerance; Hormone Antagonists; Male; Mifepristone; Morphine; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Spinal Cord; Up-Regulation | 2005 |
Central glucocorticoid receptors modulate the expression of spinal cannabinoid receptors induced by chronic morphine exposure.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Injections, Spinal; Male; Mifepristone; Morphine; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Glucocorticoid; Spinal Cord; Up-Regulation | 2005 |
Mifepristone (RU486) inhibits lateral perforant path long-term potentiation in hippocampal slices from prenatally morphine-exposed female rats.
Topics: Analgesics, Opioid; Animals; Diestrus; Electric Stimulation; Electrodes; Female; Hippocampus; Hormone Antagonists; In Vitro Techniques; Long-Term Potentiation; Mifepristone; Morphine; Neuronal Plasticity; Perforant Pathway; Pregnancy; Prenatal Exposure Delayed Effects; Proestrus; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid | 2005 |
Altered vulnerability to acute opiate withdrawal following stress: roles of N-methyl-D-aspartate and glucocorticoid receptors.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hormone Antagonists; Male; Mifepristone; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Stress, Physiological; Time Factors | 2005 |
Expression of spinal NMDA receptor and PKCgamma after chronic morphine is regulated by spinal glucocorticoid receptor.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Drug Administration Schedule; Glucocorticoids; Hormone Antagonists; Male; Mifepristone; Morphine; Oligonucleotides, Antisense; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2005 |
Morphine withdrawal modifies antinociceptive effects of acute morphine in rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Drug Tolerance; Male; Mifepristone; Morphine; Morphine Dependence; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Glucocorticoid; Stress, Psychological; Substance Withdrawal Syndrome | 2006 |
Morphine conditioned place preference depends on glucocorticoid receptors in both hippocampus and nucleus accumbens.
Topics: Animals; Conditioning, Psychological; Cues; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids; Hippocampus; Hormone Antagonists; Male; Memory; Mifepristone; Morphine; Morphine Dependence; Motivation; Narcotics; Nerve Net; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reward; Solvents | 2006 |
Metyrapone and mifepristone reverse recognition memory loss induced by spontaneous morphine withdrawal in mice.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Glucocorticoids; Hormone Antagonists; Injections, Subcutaneous; Male; Memory; Memory Disorders; Metyrapone; Mice; Mifepristone; Morphine; Receptors, Glucocorticoid; Recognition, Psychology; Steroid 11-beta-Hydroxylase; Substance Withdrawal Syndrome; Time Factors | 2008 |
Stress impairs reconsolidation of drug memory via glucocorticoid receptors in the basolateral amygdala.
Topics: Amygdala; Analgesics, Opioid; Androstanols; Animals; Association Learning; Behavior, Animal; Conditioning, Operant; Corticosterone; Drug Administration Routes; Enzyme Inhibitors; Hormone Antagonists; Male; Memory Disorders; Metyrapone; Mifepristone; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reward; Stress, Psychological | 2008 |
Functional interference of dexamethasone on some morphine effects: hypothesis for the steroid-opioid interaction.
Topics: Analysis of Variance; Animals; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Gastrointestinal Transit; Glucocorticoids; Guinea Pigs; Hormone Antagonists; Ileum; In Vitro Techniques; Male; Mice; Mifepristone; Morphine; Narcotics; Pain Measurement; Pain Threshold; Reaction Time; Statistics, Nonparametric | 2008 |
The involvement of prostaglandins and nitric oxide in the development of brain excitability: a relationship study.
Topics: Animals; Brain; Dexamethasone; Electroencephalography; Indomethacin; Male; Mice; Mifepristone; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Prostaglandins; Rabbits; Sleep; Wakefulness | 2008 |
Opioid withdrawal for 4 days prevents synaptic depression induced by low dose of morphine or naloxone in rat hippocampal CA1 area in vivo.
Topics: Analgesics, Opioid; Animals; CA1 Region, Hippocampal; Excitatory Postsynaptic Potentials; Male; Mifepristone; Morphine; Naloxone; Narcotic Antagonists; Neuronal Plasticity; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Substance Withdrawal Syndrome; Synapses; Synaptic Transmission; Time Factors | 2010 |
Blockage of glucocorticoid receptors during memory acquisition, retrieval and reconsolidation prevents the expression of morphine-induced conditioned place preferences in mice.
Topics: Animals; Memory; Mice; Mifepristone; Morphine; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reward | 2013 |
Inhibitory effects of forced swim stress and corticosterone on the acquisition but not expression of morphine-induced conditioned place preference: involvement of glucocorticoid receptor in the basolateral amygdala.
Topics: Amygdala; Analysis of Variance; Animals; Conditioning, Operant; Corticosterone; Hormone Antagonists; Male; Mifepristone; Morphine; Motor Activity; Narcotics; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress, Psychological; Swimming | 2013 |
Forced swim stress but not exogenous corticosterone could induce the reinstatement of extinguished morphine conditioned place preference in rats: involvement of glucocorticoid receptors in the basolateral amygdala.
Topics: Amygdala; Analysis of Variance; Animals; Conditioning, Operant; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Hormone Antagonists; Male; Mifepristone; Morphine; Narcotics; Rats; Rats, Wistar; Receptors, Glucocorticoid; Stress, Psychological; Swimming | 2014 |
Glucocorticoid receptor but not mineralocorticoid receptor mediates the activation of ERK pathway and CREB during morphine withdrawal.
Topics: Analgesics, Opioid; Animals; Cyclic AMP Response Element-Binding Protein; Dopamine; Hormone Antagonists; Male; MAP Kinase Signaling System; Mifepristone; Mineralocorticoid Receptor Antagonists; Morphine; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase | 2017 |
Glucocorticoid receptors in the basolateral amygdala mediated the restraint stress-induced reinstatement of methamphetamine-seeking behaviors in rats.
Topics: Amygdala; Animals; Basolateral Nuclear Complex; Conditioning, Operant; Drug-Seeking Behavior; Extinction, Psychological; Male; Methamphetamine; Mifepristone; Morphine; Rats; Rats, Wistar; Receptors, Glucocorticoid; Reward; Stress, Physiological | 2018 |
Changes in c-fos and p-CREB signaling following exposure to forced swim stress or exogenous corticosterone during morphine-induced place preference are dependent on glucocorticoid receptor in the basolateral amygdala.
Topics: Animals; Basolateral Nuclear Complex; Conditioning, Psychological; Corticosterone; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Humans; Male; Mifepristone; Morphine; Nerve Net; Nucleus Accumbens; Opioid-Related Disorders; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Receptors, Glucocorticoid; Reward; Signal Transduction; Stereotaxic Techniques; Stress, Psychological | 2020 |
Treatment With Mifepristone Allows a Patient With End-stage Pancreatic Cancer in Hospice on a Morphine Drip to Restore a Decent Quality of Life.
Topics: Analgesics, Opioid; Hormone Antagonists; Humans; Male; Middle Aged; Mifepristone; Morphine; Pancreatic Neoplasms; Quality of Life; Survival Analysis | 2020 |