mifepristone has been researched along with medroxyprogesterone acetate in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (6.98) | 18.7374 |
| 1990's | 25 (29.07) | 18.2507 |
| 2000's | 28 (32.56) | 29.6817 |
| 2010's | 25 (29.07) | 24.3611 |
| 2020's | 2 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, J; Fensome, A; Terefenko, EA; Winneker, R; Wrobel, J; Yardley, J; Zhang, P; Zhang, Z; Zhu, Y | 1 |
| Bender, R; Cohen, J; Collins, MA; Fensome, A; Hudak, V; Miller, L; Unwalla, RJ; Winneker, RC; Wrobel, J; Zhang, P; Zhang, Z; Zhu, Y | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Chen, R; Gao, JG; Mazella, J; Powell, DR; Tseng, L; Zhu, HH | 1 |
| Elias, J; Huang, JR; Mazela, J; Tseng, L; Zhu, HH | 1 |
| Bischof, P; Brioschi, PA; Herrmann, WL; Tseng, L | 1 |
| Chen, G; Huang, JR; Mazella, J; Tseng, L | 1 |
| Fujimoto, J; Fujita, H; Hosoda, S; Okada, H | 1 |
| Mazella, J; Sun, B; Tseng, L | 1 |
| Beuving, DC; Campbell, JA; Gibson, RE; Spilman, CH | 1 |
| Okada, H | 1 |
| Fan, J; Gao, JG; Mazella, J; Tseng, L; Zhu, HH | 1 |
| Nishizawa, Y; Petrow, V; Terada, N; Yamamoto, T | 1 |
| Coutts, A; Murphy, LC; Murphy, LJ | 1 |
| Charreau, EH; Dran, G; Lanari, C; Luthy, IA; Molinolo, AA; Montecchia, F; Pasqualini, CD | 1 |
| Croxatto, HB; Kekkonen, R; Lähteenmäki, P; Salvatierra, AM; Tuominen, J | 1 |
| Alkhalaf, M; Coutts, A; Dotzlaw, H; Haddad-Alkhalaf, B; Murphy, LC | 1 |
| Aigner, S; Krikun, G; Lockwood, CJ; Nemerson, Y; Papp, C; Schatz, F | 1 |
| McRae, AC | 1 |
| Lynch, M; Martin, JH; van den Berg, HW | 1 |
| Kekkonen, R; Lähteenmäki, P; Luukkainen, T; Tuominen, J | 1 |
| Joosten, JW; Kloosterboer, HJ; Schoonen, WG | 1 |
| Bamberger, AM; Bamberger, CM; Gellersen, B; Schulte, HM | 1 |
| Kekkonen, R; Lähteenmäki, P | 1 |
| Daxenbichler, G; Hofstädter, F; Marth, C; Müller-Holzner, E; Zeimet, AG | 1 |
| Croxatto, HB; Croxatto, HD; Fuentealba, B; Lähteenmäki, P; Massai, MR; Salvatierra, AM | 1 |
| Aigner, S; Hausknecht, V; Krikun, G; Lockwood, CJ; Papp, C; Schatz, F | 1 |
| Bamberger, AM; Erdmann, I; Jenatschke, S; Schulte, HM | 1 |
| Einspanier, A; Ivell, R; Kascheike, B; Lioutas, C; Walther, N | 1 |
| Tseng, L; Zhu, HH | 1 |
| Hyder, SM; Murthy, L; Stancel, GM | 1 |
| Coe, JE; Ishak, KG; Ross, MJ | 1 |
| Charreau, E; Lamb, C; Lanari, C; Luthy, IA; Molinolo, AA; Montecchia, MF; Pazos, P; Vanzulli, S | 1 |
| Demopoulos, R; Guller, S; Krikun, G; Lockwood, CJ; Mackman, N; Schatz, F | 1 |
| Arcuri, F; Carducci, A; Cintorino, M; Paulesu, L; Ricci, C; Runci, Y; Sestini, S | 1 |
| Isacson, C; New, MI; Newfield, RS; Spitz, IM | 1 |
| Chiappetta, C; Hyder, SM; Stancel, GM | 1 |
| Davidson, BP; Dogra, SC; May, BK | 1 |
| Waxman, BF | 1 |
| Busse, R; Herkert, O; Kuhl, H; Sandow, J; Schini-Kerth, VB | 1 |
| Lebovic, DI; Taylor, RN; Zhao, D | 1 |
| Ahola, TM; Aksenov, N; Pennanen, P; Purmonen, S; Tuohimaa, P; Ylikomi, T; Zhuang, YH | 1 |
| Chegini, N; Ma, C; Tang, XM; Williams, RS | 1 |
| Favata, MF; Pang, J; Trzaskos, JM; Zhao, Q | 1 |
| Felix, JC; Jain, JK; Kuo, J; Lu, JJ; Nicosia, AF; Nucatola, DL | 1 |
| Bottino, MC; Efeyan, A; Fabris, V; Gorostiaga, MA; Helguero, LA; Lamb, CA; Lanari, C; Molinolo, A; Sanjuan, N; Simian, M; Soldati, R | 1 |
| Inaba, N; Kawagoe, J; Kurachi, H; Mochizuki, Y; Mori-Abe, A; Ohmichi, M; Oishi, A; Otsu, R; Takahashi, K; Takahashi, T | 1 |
| Cano, A; García-Martínez, MC; García-Pérez, MA; Hermenegildo, C; Oviedo, PJ; Tarín, JJ | 1 |
| Ikuta, A; Kanzaki, H; Nakajima, T; Nakamoto, T; Okada, H; Yasuda, K | 1 |
| Bamberger, AM; Briese, J; Erdmann, I; Götze, J; Nollau, P; Schulte, HM; Wagener, C | 1 |
| Benakanakere, I; Besch-Williford, C; Brandt, S; Ellersieck, MR; Hyder, SM; Molinolo, A; Schnell, J | 1 |
| Baldacci, C; Caruso, A; Fornari, L; Fu, XD; Garibaldi, S; Genazzani, AR; Giretti, MS; Mannella, P; Scorticati, C; Simoncini, T | 1 |
| Felix, JC; Jain, JK; Li, A; Minoo, P; Yang, W | 1 |
| Ishii, S; Kawaminami, M; Kurusu, S | 1 |
| Baldacci, C; Caruso, A; Flamini, MI; Fu, XD; Garibaldi, S; Genazzani, AR; Giretti, MS; Mannella, P; Sanchez, AM; Simoncini, T | 1 |
| Felix, JC; Jain, JK; Li, A; Minoo, P; Xiong, DW; Yang, W | 1 |
| Dorogin, A; Langille, BL; Lye, SJ; Shynlova, O; Tsui, P | 1 |
| Besch-Williford, C; Brekken, RA; Hyder, SM; Liang, Y | 1 |
| Felix, JC; Jain, JK; Li, A; Yang, W | 1 |
| Boesch, C; Bronner, C; Hecker, M; Jourdain, M; Schini-Kerth, VB; Zerr-Fouineau, M | 1 |
| Cano, A; García-Pérez, MA; Hermenegildo, C; Laguna-Fernandez, A; Novella, S; Oviedo, PJ; Rius, C; Sobrino, A; Tarín, JJ | 1 |
| Bottino, MC; Calvo, JC; Cerliani, JP; Giulianelli, S; Gorostiaga, MA; Gutkind, JS; Lanari, C; Lüthy, IA; Molinolo, AA; Mondillo, C; Pignataro, OP; Rojas, P; Soldati, R | 1 |
| Inaba, N; Kurachi, H; Mochizuki, Y; Ohmichi, M; Oishi, A; Takahashi, K | 1 |
| Baldi, A; Cerliani, JP; Giulianelli, S; Gongora, A; Lamb, CE; Lanari, C; Molinolo, A; Sahores, A; Wargon, V | 1 |
| Du, B; Kawagoe, J; Kurachi, H; Ohta, T; Piao, S; Takahashi, K; Takata, K; Tsutsumi, S; Yamatani, H; Yin, L | 1 |
| Avenant, C; Du Toit, A; Hapgood, JP; Ray, RM; Tomasicchio, M | 1 |
| El-Demellawy, MA; El-Gowelli, HM; El-gowilly, SM; El-Mas, MM; Gohar, EY | 1 |
| Fan, P; Jordan, VC; Sweeney, EE | 1 |
| Borgatta, L; Hou, MY; McClusky, J; Sonalkar, S | 1 |
| Basar, M; Bozkurt, I; Buchwalder, L; Guzel, E; Kayisli, U; Lockwood, CJ; Ocak, N; Schatz, F | 1 |
| Ackerman, WE; Kniss, DA; Lockwood, CJ; Mesiano, S; Schatz, F; Summerfield, TL | 1 |
| Abraham, T; Arian, SE; Bartels, CB; Cayton, KC; Chuong, FS; Holthouser, K; Segars, JH | 1 |
| Geller, S; Park, J; Robinson, N; Turner, J; Wessels, U | 1 |
| Choi, MR; Christov, K; Ivancic, D; Khan, SA; Lee, O | 1 |
| Aranguré-Peraza, AG; Bousiéguez, M; Culwell, KR; Goldberg, AB; Jamshidi, R; Kaplan, C; Louie, KS; Lugo-Hernández, EM; Memmel, L; Raymond, EG; Sanhueza, P; Sonalkar, S; Tan, YL; Weaver, MA; Winikoff, B | 1 |
| McNicholas, C; Zigler, RE | 1 |
| Huang, JY; Kuo, PL; Su, MT; Tsai, YC; Tseng, JT; Wang, CY | 1 |
| Chen, MJ; Kendall, PD | 1 |
| Altinoz, MA; Elmaci, I; Ozpinar, A | 1 |
| Avenant, C; Bick, AJ; Govender, Y; Hapgood, JP; Maritz, MF; Ray, RM; Tomasicchio, M; Woodland, JG | 1 |
| Barrera, D; Becerra, RG; Díaz, L; Durand, M; García-Quiroz, J; Larrea, F; Lira-Albarrán, S; Rangel, C; Vega, C | 1 |
| Hisamatsu, Y; Kakita-Kobayashi, M; Kida, N; Kido, T; Murata, H; Okada, H; Tsuzuki, T | 1 |
| Abd Jamil, AH; Chung, I; Mat Adenan, NA; Omar, IS | 1 |
| Chung, I; Godoy, A; Gunasagran, Y; Mat Adenan, NA; Omar, IS; Teo, IH | 1 |
4 review(s) available for mifepristone and medroxyprogesterone acetate
| Article | Year |
|---|---|
Regulation of gene expression in T-47D human breast cancer cells by progestins and antiprogestins.
Topics: Breast Neoplasms; Cell Division; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Genes, myc; Gonanes; Humans; Medroxyprogesterone Acetate; Mifepristone; Neoplasm Proteins; Progestins; Transforming Growth Factors; Tumor Cells, Cultured | 1994 |
An Evidence-based Approach to the Medical Management of Fibroids: A Systematic Review.
Topics: Androgens; Aromatase Inhibitors; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Curcumin; Delayed-Action Preparations; Drugs, Chinese Herbal; Estradiol; Estrenes; Estrogen Receptor Antagonists; Evidence-Based Medicine; Female; Fulvestrant; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Intrauterine Devices, Medicated; Leiomyoma; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Neoadjuvant Therapy; Norpregnadienes; Oximes; Plant Extracts; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Tea; Uterine Myomectomy; Uterine Neoplasms; Vitamin D; Vitamins | 2016 |
Unscheduled vaginal bleeding with progestin-only contraceptive use.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Contraceptive Agents, Female; Contraceptives, Oral, Hormonal; Desogestrel; Doxycycline; Estrogens; Female; Hormone Antagonists; Humans; Intrauterine Devices, Medicated; Medroxyprogesterone Acetate; Metrorrhagia; Mifepristone; Progestins; Tamoxifen; Tranexamic Acid | 2017 |
Reproductive epidemiology of glial tumors may reveal novel treatments: high-dose progestins or progesterone antagonists as endocrino-immune modifiers against glioma.
Topics: Animals; Antineoplastic Agents, Hormonal; Brain Neoplasms; Female; Glioma; Hormone Antagonists; Humans; Medroxyprogesterone Acetate; Meningioma; Mifepristone; Norpregnadienes; Progesterone; Progestins; Receptors, Progesterone | 2019 |
9 trial(s) available for mifepristone and medroxyprogesterone acetate
| Article | Year |
|---|---|
Effects of intermittent antiprogestin RU486 combined with cyclic medroxyprogesterone acetate on folliculogenesis and ovulation.
Topics: Adult; Corpus Luteum; Drug Administration Schedule; Estradiol; Feasibility Studies; Female; Humans; Medroxyprogesterone Acetate; Menstrual Cycle; Mifepristone; Osmolar Concentration; Ovarian Follicle; Ovulation; Progesterone; Progestins; Ultrasonography | 1995 |
Effects of a sequential regimen of mifepristone-medroxyprogesterone acetate on ovarian function, endometrial development and hormonal parameters.
Topics: Adult; Biopsy; Endometrium; Estradiol; Female; Hormones; Humans; Luteinizing Hormone; Medroxyprogesterone Acetate; Menstrual Cycle; Mifepristone; Ovarian Follicle; Ovary; Ovulation; Progesterone; Time Factors; Ultrasonography | 1996 |
Mifepristone for the prevention of breakthrough bleeding in new starters of depo-medroxyprogesterone acetate.
Topics: Adult; Contraceptive Agents, Female; Contraceptives, Oral, Synthetic; Endometrium; Estrogen Receptor alpha; Estrogens; Female; Humans; Immunohistochemistry; Medroxyprogesterone Acetate; Mifepristone; Ovulation; Progesterone; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Time Factors; Uterine Hemorrhage | 2003 |
Mifepristone alters expression of endometrial steroid receptors and their cofactors in new users of medroxyprogesterone acetate.
Topics: Contraceptives, Oral, Synthetic; Double-Blind Method; Drug Combinations; Endometrium; Female; Gene Expression; Humans; Medroxyprogesterone Acetate; Mifepristone; Placebo Effect; Protein Isoforms; Receptors, Steroid | 2007 |
Effect of mifepristone on endometrial matrix metalloproteinase expression and leukocyte abundance in new medroxyprogesterone acetate users.
Topics: Adolescent; Adult; Contraceptive Agents, Female; Contraceptives, Oral, Synthetic; DNA Primers; Double-Blind Method; Endometrium; Female; Humans; Immunohistochemistry; Leukocytes; Matrix Metalloproteinases; Medroxyprogesterone Acetate; Middle Aged; Mifepristone; Prospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Treatment Outcome; Uterine Hemorrhage | 2007 |
Effect of mifepristone on the expression of endometrial secretory leukocyte protease inhibitor in new medroxyprogesterone acetate users.
Topics: Adult; Contraceptive Agents, Female; Contraceptives, Oral, Synthetic; Drug Interactions; Endometrium; Female; Gene Expression; Humans; Medroxyprogesterone Acetate; Mifepristone; Placebo Effect; Secretory Leukocyte Peptidase Inhibitor | 2008 |
Administration of depot medroxyprogesterone acetate on the day of mifepristone for medical abortion: a pilot study.
Topics: Abortifacient Agents, Steroidal; Abortion, Incomplete; Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Boston; Contraception Behavior; Contraceptive Agents, Female; Drug Implants; Female; Follow-Up Studies; Health Services Accessibility; Humans; Medroxyprogesterone Acetate; Mifepristone; Patient Acceptance of Health Care; Patient Satisfaction; Perioperative Care; Pilot Projects; Pregnancy; Pregnancy Trimester, First; Young Adult | 2015 |
Effects of Depot Medroxyprogesterone Acetate Injection Timing on Medical Abortion Efficacy and Repeat Pregnancy: A Randomized Controlled Trial.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Adolescent; Adult; Contraceptive Agents, Female; Delayed-Action Preparations; Female; Humans; Injections, Intramuscular; Medroxyprogesterone Acetate; Mifepristone; Patient Satisfaction; Pregnancy; Pregnancy Rate; Time Factors; Treatment Outcome; Young Adult | 2016 |
A single preovulatory administration of ulipristal acetate affects the decidualization process of the human endometrium during the receptive period of the menstrual cycle.
Topics: Adult; Biomarkers; Biopsy; Decidua; Endometrium; Female; Gene Expression Regulation; Humans; Medroxyprogesterone Acetate; Menstrual Cycle; Mifepristone; Models, Biological; Norpregnadienes; Ovulation; Signal Transduction; Transcription, Genetic | 2018 |
73 other study(ies) available for mifepristone and medroxyprogesterone acetate
| Article | Year |
|---|---|
Potent nonsteroidal progesterone receptor agonists: synthesis and SAR study of 6-aryl benzoxazines.
Topics: Animals; Female; Injections, Subcutaneous; Models, Animal; Molecular Structure; Ovariectomy; Oxazines; Rats; Receptors, Progesterone; Structure-Activity Relationship | 2002 |
Novel pyrrole-containing progesterone receptor modulators.
Topics: Benzoxazines; Indoles; Pyrroles; Receptors, Progesterone | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effect of progestin, antiprogestin, and relaxin on the accumulation of prolactin and insulin-like growth factor-binding protein-1 messenger ribonucleic acid in human endometrial stromal cells.
Topics: Base Sequence; Blotting, Northern; Carrier Proteins; Endometrium; Female; Humans; Insulin-Like Growth Factor Binding Protein 1; Medroxyprogesterone; Medroxyprogesterone Acetate; Mifepristone; Molecular Sequence Data; Prolactin; Relaxin; RNA, Messenger; Transcription, Genetic | 1992 |
Progestin stimulates the biosynthesis of fibronectin and accumulation of fibronectin mRNA in human endometrial stromal cells.
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Endometrium; Female; Fibronectins; Fluorescent Antibody Technique; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Mifepristone; Relaxin; RNA, Messenger | 1992 |
Cancer antigen 125 is produced by human endometrial stromal cells.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Tumor-Associated, Carbohydrate; Cells, Cultured; Cycloheximide; Danazol; Endometriosis; Endometrium; Epitopes; Estradiol; Estrenes; Female; Gonadotropin-Releasing Hormone; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Mifepristone; Triptorelin Pamoate | 1986 |
Long-term effects of progestin and RU 486 on prolactin production and synthesis in human endometrial stromal cells.
Topics: Adult; Cell Division; Cells, Cultured; DNA; Endometrium; Estrenes; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Mifepristone; Progestins; Prolactin | 1989 |
Mechanism of antitumoral activity of medroxyprogesterone acetate for endometrial cancer.
Topics: Antineoplastic Agents; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Mifepristone; Norethindrone; Receptors, Progesterone; Tumor Cells, Cultured; Tumor Stem Cell Assay; Uterine Neoplasms | 1989 |
Modulation of aromatase activity in human endometrial stromal cells by steroids, tamoxifen and RU 486.
Topics: Adult; Aromatase; Dexamethasone; Dose-Response Relationship, Drug; Endometrium; Estrenes; Female; Humans; Hydrocortisone; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Mifepristone; Norethindrone; Progesterone; Progestins; Promegestone; Steroids; Tamoxifen; Testosterone; Time Factors | 1986 |
Progestin and antiprogestin effects on progesterone receptor transformation.
Topics: Animals; Desoxycorticosterone; Estrenes; Female; Hydroxyprogesterones; Medroxyprogesterone; Medroxyprogesterone Acetate; Mifepristone; Molybdenum; Progestins; Promegestone; Protein Conformation; Rabbits; Receptors, Progesterone | 1986 |
[Progestogen therapy in the treatment of endometrial cancer--clinical results and mechanism of steroid action].
Topics: Estrenes; Female; Humans; In Vitro Techniques; Medroxyprogesterone; Medroxyprogesterone Acetate; Mifepristone; Neoplasms, Hormone-Dependent; Norethindrone; Norgestrel; Progesterone Congeners; Receptors, Progesterone; Tumor Stem Cell Assay; Uterine Neoplasms | 1988 |
Progestin and antiprogestin differentially regulate the expression of insulin-like growth factors (IGF-I and IGF-II) messenger ribonucleic acid in human endometrial stromal cells.
Topics: Cells, Cultured; Endometrium; Estradiol; Female; Gene Expression Regulation; Hormone Antagonists; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Medroxyprogesterone Acetate; Mifepristone; Progesterone Congeners; RNA, Messenger; Stromal Cells | 1995 |
Angiostatic activities of medroxyprogesterone acetate and its analogues.
Topics: Animals; Cattle; Cell Division; Cells, Cultured; Cornea; Dexamethasone; Endothelium, Vascular; Estradiol; Female; Fibroblast Growth Factor 2; Medroxyprogesterone Acetate; Mifepristone; Neovascularization, Pathologic; Progesterone; Pulmonary Artery; Rabbits; Retinal Vessels; Structure-Activity Relationship | 1994 |
Expression of insulin-like growth factor binding proteins by T-47D human breast cancer cells: regulation by progestins and antiestrogens.
Topics: Breast Neoplasms; Carrier Proteins; Culture Media, Conditioned; Dexamethasone; Estradiol; Estrogen Antagonists; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Protein 5; Medroxyprogesterone Acetate; Mifepristone; Neoplasm Proteins; Polyunsaturated Alkamides; Pregnenediones; Progesterone; Progestins; Tumor Cells, Cultured | 1994 |
Effect of medroxyprogesterone acetate (MPA) and serum factors on cell proliferation in primary cultures of an MPA-induced mammary adenocarcinoma.
Topics: Adenocarcinoma; Androgen Antagonists; Animals; Blood Physiological Phenomena; Cell Division; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Flutamide; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mifepristone; Ovariectomy; Progesterone; Tumor Cells, Cultured | 1995 |
Biological mechanisms underlying RU 486 clinical effects: inhibition of endometrial stromal cell tissue factor content.
Topics: Cells, Cultured; Dexamethasone; Endometrium; Estradiol; Female; Gene Expression; Humans; Medroxyprogesterone Acetate; Mifepristone; Progesterone; RNA, Messenger; Thromboplastin | 1994 |
Effects of the anti-progestin and anti-glucocorticoid steroid RU486 on cell proliferation in oviductal embryos of lactating mice.
Topics: Animals; Cell Division; Dexamethasone; Embryo, Mammalian; Embryonic Development; Female; Gestational Age; Gonadotropin-Releasing Hormone; Lactation; Medroxyprogesterone Acetate; Mice; Mice, Inbred Strains; Mifepristone; Pregnancy; Progesterone | 1994 |
The relationship between affinity of progestins and antiprogestins for the progesterone receptor in breast cancer cells (ZR-PR-LT) and ability to down-regulate the receptor: evidence for heterospecific receptor modulation via the glucocorticoid receptor.
Topics: Binding, Competitive; Breast Neoplasms; Dexamethasone; Down-Regulation; Female; Gonanes; Humans; Medroxyprogesterone Acetate; Mifepristone; Mitosis; Pregnenediones; Progesterone Congeners; Progestins; Receptors, Glucocorticoid; Receptors, Progesterone; Tumor Cells, Cultured | 1993 |
Sequential regimen of the antiprogesterone RU486 and synthetic progestin for contraception.
Topics: Adult; Contraceptives, Oral; Drug Administration Schedule; Estradiol; Female; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Medroxyprogesterone Acetate; Menstruation; Mifepristone; Norethindrone; Ovarian Follicle; Progesterone; Prospective Studies | 1993 |
Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines.
Topics: Breast Neoplasms; Carcinoma; Cell Division; Desogestrel; Dose-Response Relationship, Drug; Estradiol; Estrenes; Estrogen Antagonists; Female; Furans; Humans; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Nandrolone; Norethindrone; Norpregnenes; Pregnanes; Pregnenediones; Progesterone; Promegestone; Tumor Cells, Cultured | 1995 |
Modulation of AP-1 activity by the human progesterone receptor in endometrial adenocarcinoma cells.
Topics: Adenocarcinoma; Animals; Base Sequence; Cell Line; Endometrial Neoplasms; Female; Haplorhini; Hormone Antagonists; Humans; Medroxyprogesterone Acetate; Mifepristone; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, Progesterone; Transcription Factor AP-1; Transfection; Tumor Cells, Cultured | 1996 |
Cyclic progestin administration brings about luteinization during continuous antiprogestin treatment.
Topics: Adult; Contraceptive Agents, Female; Corpus Luteum; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Medroxyprogesterone Acetate; Mifepristone; Ovulation; Pilot Projects; Progesterone | 1996 |
Effects of sex- and glucocorticoid steroids on breast cancer cells grown as either multicellular tumor spheroids or monolayers.
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Division; Dexamethasone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Humans; Medroxyprogesterone Acetate; Mifepristone; Spheroids, Cellular; Steroids; Tamoxifen; Tumor Cells, Cultured | 1996 |
Biological mechanisms underlying the clinical effects of RU 486: modulation of cultured endometrial stromal cell stromelysin-1 and prolactin expression.
Topics: Cells, Cultured; Endometrium; Estradiol; Female; Gene Expression; Hormone Antagonists; Humans; Matrix Metalloproteinase 3; Medroxyprogesterone Acetate; Mifepristone; Pregnancy; Progesterone; Progestins; Prolactin; RNA, Messenger; Stromal Cells | 1997 |
Progestin-dependent stimulation of the human leukemia inhibitory factor promoter in SKUT-1B uterine tumor cells.
Topics: Female; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Interleukin-6; Jurkat Cells; Leukemia Inhibitory Factor; Lymphokines; Medroxyprogesterone Acetate; Mifepristone; Progestins; Promoter Regions, Genetic; Receptors, Progesterone; RNA, Messenger; Sequence Deletion; Transfection; Tumor Cells, Cultured; Uterine Neoplasms | 1997 |
An autocrine progesterone positive feedback loop mediates oxytocin upregulation in bovine granulosa cells during luteinization.
Topics: Animals; Blotting, Northern; Cattle; Corpus Luteum; Dexamethasone; Feedback; Female; Glucocorticoids; Gonanes; Granulosa Cells; Hormone Antagonists; Medroxyprogesterone Acetate; Mifepristone; Oxytocin; Progesterone; Progestins; RNA, Messenger | 1997 |
Regulation of progesterone receptor messenger ribonucleic acid by progestin in human endometrial stromal cells.
Topics: Cycloheximide; Dactinomycin; Endometrium; Estradiol; Female; Gene Expression Regulation; Hormone Antagonists; Humans; Immunohistochemistry; Kinetics; Medroxyprogesterone Acetate; Mifepristone; Progesterone; Progestins; Protein Synthesis Inhibitors; Receptors, Progesterone; RNA, Messenger; Stromal Cells | 1997 |
Progestin regulation of vascular endothelial growth factor in human breast cancer cells.
Topics: Breast Neoplasms; Endometrial Neoplasms; Endothelial Growth Factors; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphokines; Medroxyprogesterone Acetate; Megestrol Acetate; Mifepristone; Neoplasm Proteins; Neovascularization, Pathologic; Norethindrone; Norethynodrel; Norgestrel; Progesterone; Progestins; Receptors, Progesterone; Stimulation, Chemical; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Estrogen-induced hepatic toxicity and hepatic cancer: differences between two closely related hamster species.
Topics: Adenoma, Liver Cell; Animals; Bilirubin; Carcinoma, Hepatocellular; Cricetinae; Cricetulus; Diethylstilbestrol; Estrogens; Female; Inclusion Bodies; Liver; Liver Neoplasms, Experimental; Male; Medroxyprogesterone Acetate; Mifepristone; Species Specificity; Tamoxifen; Zeranol | 1998 |
Progesterone receptor involvement in independent tumor growth in MPA-induced murine mammary adenocarcinomas.
Topics: Adenocarcinoma; Androgens; Animals; Binding Sites; Estradiol; Female; Flutamide; Glucocorticoids; Gonanes; Hormone Antagonists; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mifepristone; Neoplasms, Hormone-Dependent; Oligonucleotides, Antisense; Ovariectomy; Receptors, Estrogen; Receptors, Progesterone; Thymidine; Tumor Cells, Cultured | 1999 |
Regulation of tissue factor gene expression in human endometrium by transcription factors Sp1 and Sp3.
Topics: Base Sequence; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Endometrium; Estradiol; Female; Gene Expression Regulation; Hormone Antagonists; Humans; Immediate-Early Proteins; Medroxyprogesterone Acetate; Menstrual Cycle; Mifepristone; Molecular Sequence Data; Progestins; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; Sp1 Transcription Factor; Sp3 Transcription Factor; Stromal Cells; Thromboplastin; Transcription Factors; Transcription, Genetic | 2000 |
Progestin regulation of 11beta-hydroxysteroid dehydrogenase expression in T-47D human breast cancer cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Breast Neoplasms; Carcinoma; Corticosterone; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Gene Expression Regulation, Enzymologic; Humans; Hydroxysteroid Dehydrogenases; Medroxyprogesterone Acetate; Mifepristone; NAD; Progesterone Congeners; Progestins; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Long-term mifepristone (RU486) therapy resulting in massive benign endometrial hyperplasia.
Topics: Adolescent; Contraceptives, Oral, Synthetic; Cushing Syndrome; Endometrial Hyperplasia; Female; Glucocorticoids; Hormone Antagonists; Humans; Magnetic Resonance Imaging; Medroxyprogesterone Acetate; Mifepristone; Osteoporosis; Progesterone; Uterus | 2001 |
Pharmacological and endogenous progestins induce vascular endothelial growth factor expression in human breast cancer cells.
Topics: Alternative Splicing; Antimetabolites, Antineoplastic; Blotting, Northern; Breast Neoplasms; Culture Media; Dactinomycin; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Estrogens; Glucocorticoids; Hormone Antagonists; Humans; Lymphokines; Medroxyprogesterone Acetate; Mifepristone; Progesterone; Progestins; Protein Isoforms; Protein Synthesis Inhibitors; Puromycin; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
The antiglucocorticoid RU486 inhibits phenobarbital induction of the chicken CYP2H1 gene in primary hepatocytes.
Topics: Animals; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enhancer Elements, Genetic; Excitatory Amino Acid Antagonists; Glucocorticoids; Hepatocytes; Hormone Antagonists; Medroxyprogesterone Acetate; Mifepristone; Phenobarbital; Pregnane X Receptor; Progesterone Congeners; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; RNA, Messenger; Transcription Factors | 2001 |
Up against eugenics: disabled women's challenge to receive reproductive health services.
Topics: Abortion, Induced; Biomedical Research; Civil Rights; Coercion; Contraception; Disabled Persons; Eugenics; Female; Freedom; Health Facilities; Health Services Research; History; Human Experimentation; Humans; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Patient Advocacy; Patient Selection; Personal Autonomy; Politics; Prejudice; Reproduction; Research; Research Subjects; Risk; Sexuality; Social Control, Formal; Social Desirability; Stereotyping; Sterilization, Reproductive; United States; Women; Women's Health; Women's Health Services; Women's Rights | 1994 |
Sex steroids used in hormonal treatment increase vascular procoagulant activity by inducing thrombin receptor (PAR-1) expression: role of the glucocorticoid receptor.
Topics: Animals; Aorta; Blood Coagulation; Blotting, Northern; Blotting, Western; Cells, Cultured; Desogestrel; Dexamethasone; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Gene Expression Regulation; Humans; In Vitro Techniques; Medroxyprogesterone Acetate; Mifepristone; Muscle, Smooth, Vascular; Norpregnenes; Ovariectomy; Progesterone; Progestins; Rats; Rats, Wistar; Receptor, PAR-1; Receptors, Glucocorticoid; Receptors, Progesterone; Receptors, Thrombin; RNA, Messenger; Thrombin; Vasoconstriction | 2001 |
Long-term progestin treatment inhibits RANTES (regulated on activation, normal T cell expressed and secreted) gene expression in human endometrial stromal cells.
Topics: Blotting, Western; Cells, Cultured; Chemokine CCL5; Drug Administration Schedule; Endometrium; Female; Gene Expression; Humans; Medroxyprogesterone Acetate; Mifepristone; NF-kappa B; Progesterone Congeners; Promoter Regions, Genetic; Response Elements; Stromal Cells; Transcription, Genetic | 2002 |
HDLG5/KIAA0583, encoding a MAGUK-family protein, is a primary progesterone target gene in breast cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Estrogens; Female; Gene Expression Profiling; Genes, Tumor Suppressor; Guanylate Kinases; Humans; Medroxyprogesterone Acetate; Membrane Proteins; Mifepristone; Nucleoside-Phosphate Kinase; Progestins; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; src Homology Domains; Tumor Cells, Cultured; Tumor Suppressor Proteins; Up-Regulation | 2002 |
Effects of GnRH analogues, 'add-back' steroid therapy, antiestrogen and antiprogestins on leiomyoma and myometrial smooth muscle cell growth and transforming growth factor-beta expression.
Topics: Estradiol; Estrogen Receptor Modulators; Female; Gonadotropin-Releasing Hormone; Gonanes; Humans; Leiomyoma; Leuprolide; Medroxyprogesterone Acetate; Mifepristone; Muscle Development; Myocytes, Smooth Muscle; Myometrium; Oligopeptides; Progestins; Steroids; Transforming Growth Factors | 2002 |
Receptor density dictates the behavior of a subset of steroid ligands in glucocorticoid receptor-mediated transrepression.
Topics: Animals; Budesonide; Chlorocebus aethiops; COS Cells; Dexamethasone; Gene Expression Regulation; Humans; Hydrocortisone; Ligands; Luciferases; Medroxyprogesterone Acetate; Mifepristone; NF-kappa B; Receptors, Glucocorticoid; Repressor Proteins; Steroids; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2003 |
Isolation of a stromal cell line from an early passage of a mouse mammary tumor line: a model for stromal parenchymal interactions.
Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Shape; Coculture Techniques; Epidermal Growth Factor; Estradiol; Female; Fibroblasts; Genetic Markers; Hormone Antagonists; Humans; Keratins; Mammary Glands, Animal; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mifepristone; Mutation; Neoplasm Transplantation; Receptors, Estrogen; Receptors, Progesterone; Stromal Cells; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Suppressor Protein p53 | 2005 |
Medroxyprogesterone acetate attenuates estrogen-induced nitric oxide production in human umbilical vein endothelial cells.
Topics: Animals; Cells, Cultured; Chlorocebus aethiops; Contraceptive Agents, Female; COS Cells; Dactinomycin; Endothelial Cells; Endothelium, Vascular; Estradiol; Female; Hormone Antagonists; Humans; Medroxyprogesterone Acetate; Mifepristone; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Progesterone; Umbilical Veins | 2004 |
Progestogens stimulate prostacyclin production by human endothelial cells.
Topics: Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Epoprostenol; Estradiol; Humans; Medroxyprogesterone Acetate; Membrane Proteins; Mifepristone; Nitrobenzenes; Progesterone; Progestins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Receptors, Progesterone; Sulfonamides; Umbilical Veins | 2005 |
Progesterone induces the fibulin-1 expression in human endometrial stromal cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adult; Calcium-Binding Proteins; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Endometrium; Estradiol; Female; Gene Expression Regulation; Hormone Antagonists; Humans; Medroxyprogesterone Acetate; Menstrual Cycle; Middle Aged; Mifepristone; Progesterone; RNA, Messenger; Stromal Cells | 2005 |
Stimulation of CEACAM1 expression by 12-O-tetradecanoylphorbol-13-acetate (TPA) and calcium ionophore A23187 in endometrial carcinoma cells.
Topics: Anti-Bacterial Agents; Antigens, CD; Calcimycin; Carcinoma; Cell Adhesion Molecules; Endometrial Neoplasms; Estradiol; Female; Hormone Antagonists; Humans; Interferon-gamma; Medroxyprogesterone Acetate; Mifepristone; Phorbol Esters; Protein Kinase C; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2006 |
Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Immunohistochemistry; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mifepristone; Neovascularization, Pathologic; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Time Factors; Vascular Endothelial Growth Factors | 2006 |
Activation of nitric oxide synthesis in human endothelial cells using nomegestrol acetate.
Topics: Cells, Cultured; Contraceptive Agents, Female; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelial Cells; Estradiol; Humans; Medroxyprogesterone Acetate; Megestrol; Mifepristone; Nitric Oxide; Nitric Oxide Synthase; Norpregnadienes; Progesterone; Progesterone Congeners; Signal Transduction | 2006 |
Changes in rat uterine and cervical phospholipase A2 activity following progesterone agonist or antagonist administration at term.
Topics: Animals; Cervix Uteri; Female; Hormone Antagonists; Labor, Obstetric; Medroxyprogesterone Acetate; Mifepristone; Phospholipases A; Phospholipases A2; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Rats, Wistar; Uterus | 2007 |
Drospirenone increases endothelial nitric oxide synthesis via a combined action on progesterone and mineralocorticoid receptors.
Topics: Aldosterone; Androstadienes; Androstenes; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Estradiol; Flavonoids; Humans; Medroxyprogesterone Acetate; Mifepristone; Nitric Oxide; Nitric Oxide Synthase Type III; Progesterone; Receptors, Mineralocorticoid; Receptors, Progesterone; Signal Transduction; Time Factors; Wortmannin | 2007 |
The expression of transforming growth factor beta in pregnant rat myometrium is hormone and stretch dependent.
Topics: Animals; Blotting, Western; Female; Gene Expression; Gravidity; Immunohistochemistry; Labor, Obstetric; Medroxyprogesterone Acetate; Mifepristone; Myometrium; Obstetric Labor, Premature; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Stress, Mechanical; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta3 | 2007 |
Progestin-dependent progression of human breast tumor xenografts: a novel model for evaluating antitumor therapeutics.
Topics: Angiogenesis Inhibitors; Animals; Aza Compounds; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Growth Processes; Disease Progression; Female; Humans; Medroxyprogesterone Acetate; Mice; Mifepristone; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Progesterone; Progesterone Congeners; Progestins; Receptors, Estrogen; Receptors, Progesterone; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2007 |
Certain progestins prevent the enhancing effect of 17beta-estradiol on NO-mediated inhibition of platelet aggregation by endothelial cells.
Topics: Blood Platelets; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Estradiol; GTP Cyclohydrolase; Hormone Antagonists; Humans; Levonorgestrel; Medroxyprogesterone Acetate; Megestrol; Mifepristone; Nitric Oxide; Nitric Oxide Synthase Type III; Norpregnadienes; Platelet Aggregation; Progesterone; Progesterone Congeners; Pterins; Receptors, Glucocorticoid; Receptors, Progesterone; RNA, Messenger; Thrombosis; Time Factors | 2009 |
Progestogens reduce thromboxane production by cultured human endothelial cells.
Topics: Antineoplastic Agents, Hormonal; Blotting, Western; Cells, Cultured; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression; Hormone Antagonists; Humans; Intramolecular Oxidoreductases; Medroxyprogesterone Acetate; Mifepristone; Polymerase Chain Reaction; Progesterone; Progestins; Pyrazoles; RNA, Messenger; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Umbilical Veins | 2011 |
Classical membrane progesterone receptors in murine mammary carcinomas: agonistic effects of progestins and RU-486 mediating rapid non-genomic effects.
Topics: Animals; Female; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Animal; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Microscopy, Fluorescence; Mifepristone; Neoplasm Transplantation; Progestins; Receptors, Progesterone; Steroids | 2011 |
Role of glucocorticoid receptor in the inhibitory effect of medroxyprogesterone acetate on the estrogen-induced endothelial nitric oxide synthase phosphorylation in human umbilical vein endothelial cells.
Topics: Atherosclerosis; Cells, Cultured; Contraceptive Agents, Female; Endothelial Cells; Estrogens; Hormone Antagonists; Humans; Medroxyprogesterone Acetate; Mifepristone; Nitric Oxide Synthase Type III; Phosphorylation; Receptors, Glucocorticoid; Risk Factors; RNA, Small Interfering; Umbilical Veins | 2011 |
Mifepristone inhibits MPA-and FGF2-induced mammary tumor growth but not FGF2-induced mammary hyperplasia.
Topics: Animals; Disease Models, Animal; Female; Fibroblast Growth Factor 2; Hormone Antagonists; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Animal; Medroxyprogesterone Acetate; Mice; Mifepristone | 2010 |
Estrogen induces neurite outgrowth via Rho family GTPases in neuroblastoma cells.
Topics: Cell Line, Tumor; Estradiol; Humans; Medroxyprogesterone Acetate; Mifepristone; Neurites; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Progesterone; Proto-Oncogene Proteins c-akt; rho GTP-Binding Proteins; Signal Transduction; Tumor Cells, Cultured | 2011 |
The progestin-only contraceptive medroxyprogesterone acetate, but not norethisterone acetate, enhances HIV-1 Vpr-mediated apoptosis in human CD4+ T cells through the glucocorticoid receptor.
Topics: Amino Acid Sequence; Apoptosis; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cells, Cultured; Contraceptive Agents, Female; Dexamethasone; Gene Expression Regulation; Gene Products, vpr; HIV-1; Humans; Hydrocortisone; Medroxyprogesterone Acetate; Mifepristone; Molecular Sequence Data; Norethindrone; Norethindrone Acetate; Progesterone; Receptors, Estrogen; Receptors, Glucocorticoid; Signal Transduction | 2013 |
PI3K/Akt-independent NOS/HO activation accounts for the facilitatory effect of nicotine on acetylcholine renal vasodilations: modulation by ovarian hormones.
Topics: Acetylcholine; Adenosine-5'-(N-ethylcarboxamide); Animals; Area Under Curve; Arginine; Enzyme Activation; Estradiol; Female; Heme Oxygenase (Decyclizing); Hemin; Hormones; In Vitro Techniques; Kidney; Medroxyprogesterone Acetate; Mifepristone; Nicotine; Nitric Oxide Synthase; Papaverine; Phenylephrine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Wistar; Signal Transduction; Vasodilation | 2014 |
Molecular modulation of estrogen-induced apoptosis by synthetic progestins in hormone replacement therapy: an insight into the women's health initiative study.
Topics: Apoptosis; Breast Neoplasms; Dexamethasone; Estrogens; Female; Glucocorticoids; Hormone Replacement Therapy; Humans; MCF-7 Cells; Medroxyprogesterone Acetate; Mifepristone; Norethindrone; Norethindrone Acetate; Postmenopause; Progesterone Congeners; Receptors, Estrogen; Receptors, Glucocorticoid; Risk; Women's Health | 2014 |
Effects of tibolone and its metabolites on prolactin and insulin-like growth factor binding protein-1 expression in human endometrial stromal cells.
Topics: Blotting, Western; Contraceptive Agents, Female; Dexamethasone; Endometrium; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrenes; Estrogen Receptor Modulators; Estrogens; Female; Furans; Glucocorticoids; Hormone Antagonists; Humans; Insulin-Like Growth Factor Binding Protein 1; Medroxyprogesterone Acetate; Mifepristone; Norpregnanes; Norpregnenes; Prolactin; Real-Time Polymerase Chain Reaction; RNA, Messenger; Stromal Cells | 2015 |
Agonist-Dependent Downregulation of Progesterone Receptors in Human Cervical Stromal Fibroblasts.
Topics: Cervix Uteri; Down-Regulation; Estradiol; Female; Fibroblasts; Hormone Antagonists; Humans; Medroxyprogesterone Acetate; Mifepristone; Pregnenediones; Receptors, Glucocorticoid; Receptors, Progesterone | 2016 |
Progestin-based contraceptive on the same day as medical abortion.
Topics: Abortion, Induced; Adolescent; Adult; Contraceptive Agents, Female; Contraceptive Devices, Female; Desogestrel; Female; Humans; Medroxyprogesterone Acetate; Middle Aged; Mifepristone; Misoprostol; Pregnancy; Progestins; Retrospective Studies; South Africa; Time Factors; Young Adult | 2016 |
Progesterone receptor antagonism inhibits progestogen-related carcinogenesis and suppresses tumor cell proliferation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antigens, CD34; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Methylnitrosourea; Mice; Mifepristone; Neovascularization, Pathologic; Norpregnadienes; Progesterone; Progestins; Rats; Receptors, Estrogen; Receptors, Progesterone; Time Factors | 2016 |
Medroxyprogesterone acetate drives M2 macrophage differentiation toward a phenotype of decidual macrophage.
Topics: Butadienes; Cell Differentiation; Cytokines; Decidua; Endometritis; Enzyme Inhibitors; Female; Hormone Antagonists; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Macrophages; Medroxyprogesterone Acetate; Mifepristone; Monocytes; Nitric Oxide Synthase Type II; Nitriles; Pregnancy; Primary Cell Culture; Stromal Cells; Tetradecanoylphorbol Acetate; THP-1 Cells; Trophoblasts | 2017 |
Case report of induced medical abortion following depot administration of medroxyprogesterone acetate.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Adult; Ambulatory Care; Contraception; Contraceptive Agents, Female; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Therapy, Combination; Female; Humans; Medroxyprogesterone Acetate; Mifepristone; Misoprostol; Pregnancy; Treatment Outcome | 2017 |
Medroxyprogesterone acetate, unlike norethisterone, increases HIV-1 replication in human peripheral blood mononuclear cells and an indicator cell line, via mechanisms involving the glucocorticoid receptor, increased CD4/CD8 ratios and CCR5 levels.
Topics: CD4 Antigens; CD4-CD8 Ratio; Cell Line; Female; HEK293 Cells; HIV-1; Humans; Leukocytes, Mononuclear; Medroxyprogesterone Acetate; Mifepristone; Norethindrone; Receptors, CCR5; Receptors, Glucocorticoid; RNA Interference; RNA, Small Interfering; T-Lymphocytes; Up-Regulation; Virus Replication | 2018 |
Progestin-induced heart and neural crest derivatives-expressed transcript 2 inhibits angiopoietin 2 via fibroblast growth factor 9 in human endometrial stromal cells.
Topics: Angiopoietin-2; Basic Helix-Loop-Helix Transcription Factors; Endometrium; Estradiol; Female; Fibroblast Growth Factor 9; Gene Expression Regulation; Humans; Luteolytic Agents; Medroxyprogesterone Acetate; Mifepristone; Progestins; RNA, Messenger; RNA, Small Interfering; Stromal Cells | 2019 |
MPA alters metabolic phenotype of endometrial cancer-associated fibroblasts from obese women via IRS2 signaling.
Topics: Acetates; Cancer-Associated Fibroblasts; Endometrial Neoplasms; Female; Glucose; Humans; Insulin Receptor Substrate Proteins; Medroxyprogesterone Acetate; Mifepristone; Neoplasm Recurrence, Local; Obesity; Phenotype; Progesterone; Receptors, Progesterone; RNA, Messenger | 2022 |
Aberrant upregulation of CDK1 contributes to medroxyprogesterone acetate (MPA) resistance in cancer-associated fibroblasts of the endometrium.
Topics: Cancer-Associated Fibroblasts; CDC2 Protein Kinase; Drug Resistance, Neoplasm; Endometrial Neoplasms; Endometrium; Female; Humans; Luciferases; Medroxyprogesterone Acetate; Mifepristone; Neoplasms; Receptors, Progesterone; RNA, Messenger; Up-Regulation | 2022 |