Compounds > mifepristone
Page last updated: 2024-08-23

mifepristone and cort 108297

mifepristone has been researched along with cort 108297 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Belanoff, J; Blaney, P; Bright, CP; Clark, DE; Clark, RD; Crackett, PH; Devos, R; Dyke, HJ; Hurley, C; Jenkins, RE; Lockey, P; Porres, SS; Ray, NC; Ward, S; Williams, K; Wong, M1
Belanoff, JK; Golding, E; Gourdet, B; Hunt, HJ; Phillips, T; Swift, D; Thomas, J; Unitt, JF; Walters, I1
Butts, KA; Phillips, AG1
Alexander-Chacko, J; Barr, RJ; Carson, MW; Coghlan, M; Gehlert, DR; Morin, M; Need, A; Shaw, J; Sindelar, DK1
Flak, JN; Herman, JP; McKlveen, J; Myers, B; Rice, T; Solomon, MB; Ulrich-Lai, Y; Wick, D; Wulsin, AC1
Belanoff, JK; Canet, G; Chevallier, N; Desrumaux, C; Givalois, L; Hunt, H; Ollivier, M; Pineau, F1
Koorneef, LL; Kroon, J; Meijer, OC1
de Guglielmo, G; George, O; Gregory-Flores, A; Hunt, HJ; Koob, GF; Mason, BJ; McGinn, MA; Schlosburg, JE; Tunstall, BJ; Vendruscolo, LF1

Reviews

1 review(s) available for mifepristone and cort 108297

ArticleYear
Glucocorticoid receptor modulators.
    Annales d'endocrinologie, 2018, Volume: 79, Issue:3

    Topics: Animals; Aza Compounds; Glucocorticoids; Heterocyclic Compounds, 4 or More Rings; Humans; Ligands; Mifepristone; Receptors, Glucocorticoid; Signal Transduction; Thymine

2018

Other Studies

7 other study(ies) available for mifepristone and cort 108297

ArticleYear
1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity.
    Bioorganic & medicinal chemistry letters, 2008, Feb-15, Volume: 18, Issue:4

    Topics: Animals; Aza Compounds; Dogs; Isoquinolines; Kinetics; Pyrazoles; Rats; Receptors, Glucocorticoid; Structure-Activity Relationship

2008
1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile.
    Bioorganic & medicinal chemistry letters, 2015, Dec-15, Volume: 25, Issue:24

    Topics: Animals; Binding Sites; Catalytic Domain; Cell Line; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Hep G2 Cells; Humans; Isoquinolines; Molecular Docking Simulation; Protein Binding; Pyrazoles; Rats; Receptors, Glucocorticoid; Structure-Activity Relationship; Sulfonamides

2015
Glucocorticoid receptors in the prefrontal cortex regulate dopamine efflux to stress via descending glutamatergic feedback to the ventral tegmental area.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:8

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Area Under Curve; Aza Compounds; Chromatography, High Pressure Liquid; Dopamine; Efferent Pathways; Excitatory Amino Acid Antagonists; Glutamic Acid; Heterocyclic Compounds, 4 or More Rings; Hormone Antagonists; Male; Microdialysis; Mifepristone; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Physiological; Tail; Valine; Ventral Tegmental Area

2013
LLY-2707, a novel nonsteroidal glucocorticoid antagonist that reduces atypical antipsychotic-associated weight gain in rats.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:1

    Topics: Animals; Antipsychotic Agents; Aza Compounds; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Female; HEK293 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Male; Mice; Mice, Inbred C57BL; Mifepristone; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Sulfonamides; Weight Gain; Weight Loss

2014
The selective glucocorticoid receptor antagonist CORT 108297 decreases neuroendocrine stress responses and immobility in the forced swim test.
    Hormones and behavior, 2014, Volume: 65, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Aza Compounds; Behavior, Animal; Corticosterone; Heterocyclic Compounds, 4 or More Rings; Hormone Antagonists; Imipramine; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Stress, Psychological

2014
New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity.
    Neurobiology of aging, 2016, Volume: 45

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aza Compounds; Cognitive Dysfunction; Disease Models, Animal; Dose-Response Relationship, Drug; Glucocorticoids; Heterocyclic Compounds, 4 or More Rings; Hippocampus; Hypothalamo-Hypophyseal System; Isoquinolines; Male; Mifepristone; Molecular Targeted Therapy; Pituitary-Adrenal System; Pyrazoles; Rats, Sprague-Dawley; Receptors, Glucocorticoid

2016
Glucocorticoid receptor modulators decrease alcohol self-administration in male rats.
    Neuropharmacology, 2021, 05-01, Volume: 188

    Topics: Animals; Aza Compounds; Ethanol; Heterocyclic Compounds, 4 or More Rings; Isoquinolines; Male; Mifepristone; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptors, Glucocorticoid; Self Administration; Thymine

2021