Page last updated: 2024-08-23

mifepristone and afimoxifene

mifepristone has been researched along with afimoxifene in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's5 (31.25)18.2507
2000's4 (25.00)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Gronemeyer, H1
Gompel, A; Kuttenn, F; Malet, C; Mauvais-Jarvis, P2
Chambon, P; Green, S; Jin, JR; Webster, NJ1
Bardon, S; Montcourrier, P; Rochefort, H; Vignon, F1
Baulieu, EE; Jung-Testas, I1
Daxenbichler, G; Hofstädter, F; Marth, C; Müller-Holzner, E; Zeimet, AG1
Gurpide, E; Markiewicz, L1
Bagchi, MK; Jeyakumar, M; Petukhov, S; Zhang, X1
El Etreby, MF; Lewis, RW; Liang, Y1
Barrett, JT; El Etreby, F; Hou, M; Kallab, AM; Liang, Y; Schoenlein, PV1
Barrett, JT; Delk, JN; Gaddy, VT; Kallab, AM; Porter, AG; Schoenlein, PV1
Barrett, JT; Gaddy, VT; Ganapathy, V; Hou, M; Johnson, M; Kallab, A; Lewis, J; Samaddar, JS; Schoenlein, PV; Thangaraju, M1
Dohn, MR; Huang, S; Jackson, WH; LeRoith, D; Marrero, M; Periyasamy-Thandavan, S; Schoenlein, PV; Singer, A; Takhar, S; Thangaraju, M; Welborn, AE1
Gajewska, M; Sobolewska, A; Zielniok, K1

Reviews

2 review(s) available for mifepristone and afimoxifene

ArticleYear
Transcription activation by estrogen and progesterone receptors.
    Annual review of genetics, 1991, Volume: 25

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Gene Expression Regulation; Humans; Ligands; Mifepristone; Molecular Sequence Data; Phosphorylation; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Regulatory Sequences, Nucleic Acid; Tamoxifen; Transcription Factors; Transcription, Genetic; Zinc Fingers

1991
[Antiestrogens and normal human breast cell proliferation].
    Annales d'endocrinologie, 1989, Volume: 50, Issue:3

    Topics: 17-Hydroxysteroid Dehydrogenases; Breast; Cell Division; Estradiol; Estrogen Antagonists; Humans; Mifepristone; Progestins; Promegestone; Receptors, Estrogen; Stereoisomerism; Tamoxifen

1989

Other Studies

14 other study(ies) available for mifepristone and afimoxifene

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Normal breast cells in culture. Effect of estrogens, progestins, and antiestrogens.
    Annals of the New York Academy of Sciences, 1990, Volume: 595

    Topics: 17-Hydroxysteroid Dehydrogenases; Breast; Cell Division; Cells, Cultured; Epithelial Cells; Estradiol; Estrogens; Humans; In Vitro Techniques; Mifepristone; Progestins; Promegestone; Tamoxifen

1990
The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function.
    Cell, 1988, Jul-15, Volume: 54, Issue:2

    Topics: DNA; Estradiol; Estrenes; Estrogen Antagonists; Estrogens; Glucocorticoids; HeLa Cells; Hormones; Humans; Mifepristone; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Glucocorticoid; Tamoxifen; Transcription Factors; Transcription, Genetic; Transfection

1988
Steroid receptor-mediated cytotoxicity of an antiestrogen and an antiprogestin in breast cancer cells.
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Breast Neoplasms; Cell Survival; Estradiol; Estrenes; Estrogen Antagonists; Female; Humans; Mifepristone; Progestins; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

1987
Anti-steroid action in cultured L-929 mouse fibroblasts.
    Journal of steroid biochemistry, 1984, Volume: 20, Issue:1

    Topics: Animals; Cell Adhesion; Cell Division; Centrifugation, Density Gradient; Dexamethasone; Estradiol; Estrenes; Estrogen Antagonists; Fibroblasts; Mice; Mifepristone; Receptors, Estrogen; Receptors, Glucocorticoid; Tamoxifen

1984
Effects of sex- and glucocorticoid steroids on breast cancer cells grown as either multicellular tumor spheroids or monolayers.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 58, Issue:1

    Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Division; Dexamethasone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Humans; Medroxyprogesterone Acetate; Mifepristone; Spheroids, Cellular; Steroids; Tamoxifen; Tumor Cells, Cultured

1996
Estrogenic and progestagenic activities of physiologic and synthetic androgens, as measured by in vitro bioassays.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:4

    Topics: Adenocarcinoma; Alkaline Phosphatase; Androgen Antagonists; Androgens; Breast Neoplasms; Cyproterone Acetate; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Flutamide; Gonanes; Humans; Mifepristone; Polyunsaturated Alkamides; Progestins; Tamoxifen; Testosterone; Testosterone Congeners; Tumor Cells, Cultured

1997
A nuclear receptor corepressor modulates transcriptional activity of antagonist-occupied steroid hormone receptor.
    Molecular endocrinology (Baltimore, Md.), 1998, Volume: 12, Issue:4

    Topics: Animals; Binding Sites; Cell Line; Chlorocebus aethiops; Humans; Kidney; Ligands; Mice; Mifepristone; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Peptides; Progesterone; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Receptors, Steroid; Receptors, Thyroid Hormone; Repressor Proteins; Tamoxifen; Transcription, Genetic; Transcriptional Activation

1998
Induction of apoptosis by mifepristone and tamoxifen in human LNCaP prostate cancer cells in culture.
    The Prostate, 2000, Apr-01, Volume: 43, Issue:1

    Topics: Animals; Antibodies; Apoptosis; Cell Division; Cell Survival; DNA Fragmentation; Estrogen Antagonists; Hormone Antagonists; Humans; Male; Mannosephosphates; Mice; Mice, Nude; Mifepristone; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Tamoxifen; Transforming Growth Factor beta; Tumor Cells, Cultured

2000
Induction of antiproliferation and apoptosis in estrogen receptor negative MDA-231 human breast cancer cells by mifepristone and 4-hydroxytamoxifen combination therapy: a role for TGFbeta1.
    International journal of oncology, 2003, Volume: 23, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Caspases; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cytochromes c; Drug Synergism; Drug Therapy, Combination; Estrogen Antagonists; Female; Humans; Mifepristone; Receptors, Estrogen; Retinoblastoma Protein; Tamoxifen; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Tumor Suppressor Proteins; Up-Regulation

2003
Mifepristone induces growth arrest, caspase activation, and apoptosis of estrogen receptor-expressing, antiestrogen-resistant breast cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-01, Volume: 10, Issue:15

    Topics: Apoptosis; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Proliferation; Coloring Agents; DNA Fragmentation; Drug Resistance, Neoplasm; Enzyme Activation; Estradiol; Estrogen Receptor Modulators; Fulvestrant; G1 Phase; Hormone Antagonists; Humans; Immunoblotting; Mifepristone; Phosphorylation; Receptors, Estrogen; Receptors, Progesterone; Resting Phase, Cell Cycle; Tamoxifen; Tetrazolium Salts; Thiazoles; Time Factors

2004
Downregulation of retinoblastoma protein is involved in the enhanced cytotoxicity of 4-hydroxytamoxifen plus mifepristone combination therapy versus antiestrogen monotherapy of human breast cancer.
    International journal of oncology, 2007, Volume: 31, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Down-Regulation; Estrogen Antagonists; Estrogens; Gene Expression Regulation, Neoplastic; Humans; Mifepristone; Retinoblastoma Protein; RNA, Small Interfering; Tamoxifen

2007
Insulin-like growth factor 1 attenuates antiestrogen- and antiprogestin-induced apoptosis in ER+ breast cancer cells by MEK1 regulation of the BH3-only pro-apoptotic protein Bim.
    Breast cancer research : BCR, 2012, Mar-19, Volume: 14, Issue:2

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Breast Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; Estrogen Antagonists; Estrogen Receptor Modulators; Female; Hormone Antagonists; Humans; Insulin-Like Growth Factor I; MAP Kinase Kinase 1; Membrane Proteins; Mifepristone; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptors, Estrogen; Tamoxifen

2012
Mechanisms of autophagy induction by sex steroids in bovine mammary epithelial cells.
    Journal of molecular endocrinology, 2017, Volume: 59, Issue:1

    Topics: Animals; Autophagy; Autophagy-Related Protein 5; Beclin-1; Cattle; Cell Line; Culture Media; Epithelial Cells; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation; Mammary Glands, Animal; Microtubule-Associated Proteins; Mifepristone; Phosphorylation; Progesterone; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tamoxifen

2017