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mifepristone and 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione

mifepristone has been researched along with 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's12 (85.71)18.2507
2000's0 (0.00)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clarke, CL; Kelly, PA; Ormandy, CJ; Sutherland, RL1
Lee, CS; Musgrove, EA; Sutherland, RL1
Beery, R; Bella, R; Geier, A; Lunenfeld, B1
Beery, R; Bella, R; Geier, A; Haimsohn, M; Lunenfeld, B1
Coutts, A; Murphy, LC; Murphy, LJ1
Falkay, G; Földesi, I; Kovács, L1
Musgrove, EA; Sutherland, RL1
Lynch, M; Martin, JH; van den Berg, HW1
Hamilton, JA; Lee, CS; Musgrove, EA; Sutherland, RL; Sweeney, KJ; Watts, CK1
Joosten, JW; Kloosterboer, HJ; Schoonen, WG1
Bigsby, RM; Young, PC1
Brouwer, A; Kuil, CW; van der Burg, B; van der Saag, PT1
Borras, M; Lacroix, M; Leclercq, G; Legros, N1
Ackerman, WE; Kniss, DA; Lockwood, CJ; Mesiano, S; Schatz, F; Summerfield, TL1

Other Studies

14 other study(ies) available for mifepristone and 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione

ArticleYear
Androgen regulation of prolactin-receptor gene expression in MCF-7 and MDA-MB-453 human breast cancer cells.
    International journal of cancer, 1992, Mar-12, Volume: 50, Issue:5

    Topics: Androgens; Breast Neoplasms; Dihydrotestosterone; Female; Gene Expression Regulation; Humans; Mifepristone; Pregnenediones; Receptors, Prolactin; RNA, Messenger; Tumor Cells, Cultured

1992
Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes.
    Molecular and cellular biology, 1991, Volume: 11, Issue:10

    Topics: Blotting, Northern; Breast Neoplasms; Cell Cycle; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Kinetics; Mifepristone; Pregnenediones; Progesterone Congeners; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Transforming Growth Factor alpha; Tumor Cells, Cultured

1991
Comparison of the physical properties of the nuclear progesterone receptor, bound to antiprogestin RU 486 or progestin ORG 2058, following limited proteolysis.
    Steroids, 1990, Volume: 55, Issue:6

    Topics: Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Micrococcal Nuclease; Mifepristone; Molecular Weight; Peptide Fragments; Pregnenediones; Progesterone Congeners; Receptors, Progesterone; Trypsin

1990
Differences in the association of the progesterone receptor ligated by antiprogestin RU38486 or progestin ORG 2058 to chromatin components.
    Biochimica et biophysica acta, 1987, Oct-22, Volume: 931, Issue:1

    Topics: Cell Line; Centrifugation, Density Gradient; Chromatin; Chromatography, Gel; Cross-Linking Reagents; Estrenes; Imidoesters; Micrococcal Nuclease; Mifepristone; Molecular Weight; Pregnenediones; Progesterone Congeners; Progestins; Receptors, Progesterone

1987
Expression of insulin-like growth factor binding proteins by T-47D human breast cancer cells: regulation by progestins and antiestrogens.
    Breast cancer research and treatment, 1994, Volume: 32, Issue:2

    Topics: Breast Neoplasms; Carrier Proteins; Culture Media, Conditioned; Dexamethasone; Estradiol; Estrogen Antagonists; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Protein 5; Medroxyprogesterone Acetate; Mifepristone; Neoplasm Proteins; Polyunsaturated Alkamides; Pregnenediones; Progesterone; Progestins; Tumor Cells, Cultured

1994
[Pharmacokinetics of RU 486 and its active metabolites in humans].
    Acta pharmaceutica Hungarica, 1994, Volume: 64, Issue:1

    Topics: Female; Humans; Metabolic Clearance Rate; Mifepristone; Models, Biological; Myometrium; Pregnenediones; Progesterone Congeners; Radioligand Assay; Receptors, Progesterone; Tissue Distribution; Tritium

1994
Effects of the progestin antagonist RU 486 on T-47D breast cancer cell cycle kinetics and cell cycle regulatory genes.
    Biochemical and biophysical research communications, 1993, Sep-30, Volume: 195, Issue:3

    Topics: Breast Neoplasms; Cell Cycle; Cyclin D1; Cyclins; Dose-Response Relationship, Drug; Estradiol; Humans; Mifepristone; Oncogene Proteins; Polyunsaturated Alkamides; Pregnenediones; Progesterone Congeners; Progestins; Proto-Oncogene Proteins c-myc; RNA, Messenger; S Phase; Tumor Cells, Cultured

1993
The relationship between affinity of progestins and antiprogestins for the progesterone receptor in breast cancer cells (ZR-PR-LT) and ability to down-regulate the receptor: evidence for heterospecific receptor modulation via the glucocorticoid receptor.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:12

    Topics: Binding, Competitive; Breast Neoplasms; Dexamethasone; Down-Regulation; Female; Gonanes; Humans; Medroxyprogesterone Acetate; Mifepristone; Mitosis; Pregnenediones; Progesterone Congeners; Progestins; Receptors, Glucocorticoid; Receptors, Progesterone; Tumor Cells, Cultured

1993
Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression.
    Molecular and cellular biology, 1993, Volume: 13, Issue:6

    Topics: Breast Neoplasms; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Cycle; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cyclins; DNA, Neoplasm; Estradiol; Estrogen Antagonists; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Genes, myc; Growth Substances; Histones; Humans; Insulin; Kinetics; Mifepristone; Polyunsaturated Alkamides; Pregnenediones; Progesterone Congeners; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Cells, Cultured

1993
Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4

    Topics: Breast Neoplasms; Carcinoma; Cell Division; Desogestrel; Dose-Response Relationship, Drug; Estradiol; Estrenes; Estrogen Antagonists; Female; Furans; Humans; Levonorgestrel; Medroxyprogesterone Acetate; Mifepristone; Nandrolone; Norethindrone; Norpregnenes; Pregnanes; Pregnenediones; Progesterone; Promegestone; Tumor Cells, Cultured

1995
Progesterone and dexamethasone inhibition of uterine epithelial cell proliferation: studies with antiprogesterone compounds in the neonatal mouse.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:2

    Topics: Animals; Animals, Newborn; Cell Division; Dexamethasone; Epithelial Cells; Epithelium; Female; Hormone Antagonists; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mifepristone; Pregnenediones; Progesterone; Receptors, Glucocorticoid; Receptors, Progesterone; Uterus

1993
Interference between progesterone and dioxin signal transduction pathways. Different mechanisms are involved in repression by the progesterone receptor A and B isoforms.
    The Journal of biological chemistry, 1998, Apr-10, Volume: 273, Issue:15

    Topics: Breast Neoplasms; Cytochrome P-450 CYP1A1; Female; Gene Expression Regulation, Enzymologic; Gonanes; Hormone Antagonists; Humans; Mifepristone; Polychlorinated Dibenzodioxins; Pregnenediones; Progesterone Congeners; Receptors, Aryl Hydrocarbon; Receptors, Progesterone; Recombinant Proteins; Signal Transduction; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Up-Regulation

1998
Estrogen receptor-negative/progesterone receptor-positive Evsa-T mammary tumor cells: a model for assessing the biological property of this peculiar phenotype of breast cancers.
    Cancer letters, 1997, Nov-25, Volume: 120, Issue:1

    Topics: Breast Neoplasms; Cell Division; Cytosol; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Gonanes; Hormone Antagonists; Humans; Mifepristone; Pregnenediones; Progestins; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured

1997
Agonist-Dependent Downregulation of Progesterone Receptors in Human Cervical Stromal Fibroblasts.
    Reproductive sciences (Thousand Oaks, Calif.), 2016, Volume: 23, Issue:1

    Topics: Cervix Uteri; Down-Regulation; Estradiol; Female; Fibroblasts; Hormone Antagonists; Humans; Medroxyprogesterone Acetate; Mifepristone; Pregnenediones; Receptors, Glucocorticoid; Receptors, Progesterone

2016