midesteine has been researched along with thiophenes in 6 studies
*Thiophenes: A monocyclic heteroarene furan in which the oxygen atom is replaced by a sulfur. [MeSH]
*Thiophenes: A monocyclic heteroarene furan in which the oxygen atom is replaced by a sulfur. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alesina, R; Donnetta, AM; Donnini, M; Luisetti, M; Peona, V; Piccioni, PD | 1 |
| Galzigna, L; Gentili, P; La Rosa, C; Lucarelli, C; Pelloso, R | 1 |
| Baici, A; Hörler, D; Pelloso, R | 1 |
| Donnini, M; Grassi, C; Luisetti, M; Peona, V; Piccioni, PD; Pozzi, E | 1 |
| Baldini, EV; Donnetta, AM; Gorrini, M; Iadarola, P; Luisetti, M; Marchioni, CF; Moretti, M; Venturini, R | 1 |
| Bruno, G; Dagnino, G; Galavotti, V; Grassi, C; Kucich, U; Luisetti, M; Madonini, E; Peona, V; Rosenbloom, J; Sella, D; Starcher, B; Sturani, C | 1 |
1 trial(s) available for midesteine and thiophenes
| Article | Year |
|---|---|
MR889, a neutrophil elastase inhibitor, in patients with chronic obstructive pulmonary disease: a double-blind, randomized, placebo-controlled clinical trial.
Topics: Aged; Desmosine; Double-Blind Method; Drug Administration Schedule; Elastin; Female; Humans; Leukocyte Elastase; Lung Diseases, Obstructive; Male; Protease Inhibitors; Thiophenes; Time Factors | 1996 |
5 other study(ies) available for midesteine and thiophenes
| Article | Year |
|---|---|
On the activity of MR 889, a new synthetic proteinase inhibitor.
Topics: alpha-Macroglobulins; Humans; Leukocyte Elastase; Pancreatic Elastase; Protease Inhibitors; Thiophenes | 1991 |
Absorption, distribution, metabolism and excretion of 2-[2-thiophenecarboxythio]-N-[dihydro-2-(3H)-thiophenone-3-yl]-propiona mide in the rat.
Topics: Administration, Oral; Animals; Biotransformation; Chromatography, High Pressure Liquid; Feces; Injections, Intraperitoneal; Intestinal Absorption; Male; Protease Inhibitors; Rats; Rats, Inbred Strains; Stereoisomerism; Sulfhydryl Compounds; Thiophenes; Tissue Distribution | 1990 |
The kinetic mechanism of inhibition of human leukocyte elastase by MR889, a new cyclic thiolic compound.
Topics: Cathepsin B; Cathepsin G; Cathepsins; Chymotrypsin; Humans; In Vitro Techniques; Kinetics; Leukocyte Elastase; Pancreatic Elastase; Protease Inhibitors; Serine Endopeptidases; Substrate Specificity; Thiophenes | 1990 |
Studies of MR 889, a new synthetic proteinase inhibitor.
Topics: Chymotrypsin; Humans; Kinetics; Pancreatic Elastase; Protease Inhibitors; Sputum; Thiophenes | 1989 |
Effects of MR889, a cyclic thiolic neutrophil elastase inhibitor, on rheologic properties of mucus.
Topics: alpha 1-Antitrypsin; Animals; Bronchitis; Chronic Disease; Elasticity; Gastric Mucosa; Humans; In Vitro Techniques; Leukocyte Elastase; Mucus; Pancreatic Elastase; Sputum; Swine; Thiophenes; Viscosity | 1994 |