midazolam has been researched along with ursodeoxycholic acid in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Becquemont, L; Burk, O; Drescher, S; Eichelbaum, M; Fromm, MF; Glaeser, H; Heinkele, G; Hitzl, M; Hofmann, U; Murdter, TE; Schaefer, C; Simon, N; Verstuyft, C | 1 |
| Inui, N; Luo, J; Misaka, S; Ohashi, K; Takeuchi, K; Uchida, S; Watanabe, H; Yamada, S; Yan, D; Yang, Y | 1 |
| Ito, Y; Kurosawa, S; Uchida, S; Yamada, S | 1 |
| Kagawa, Y; Kato, Y; Kurosawa, S; Misaka, S; Uchida, S; Yamada, S; Yoshida, A | 1 |
| Al Eisa, N; Burkert, KR; Cluzeau, CV; Cologna, SM; Figg, WD; Gray, J; Morris, L; Nicoli, ER; Pavan, WJ; Peer, CJ; Platt, FM; Porter, FD; Sissung, TM; Smith, DA; Uscatu, CD; Vite, CH; Wassif, CA | 1 |
1 review(s) available for midazolam and ursodeoxycholic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for midazolam and ursodeoxycholic acid
| Article | Year |
|---|---|
Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Digoxin; Enzyme Activators; Humans; In Vitro Techniques; Intestinal Mucosa; Intestines; Leukocytes; Male; Midazolam; RNA, Messenger; Ursodeoxycholic Acid | 2006 |
Effects of ursodeoxycholic acid on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam in healthy volunteers.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Cholagogues and Choleretics; Cross-Over Studies; Cytochrome P-450 CYP3A; Drug Interactions; Female; Humans; Injections, Intravenous; Male; Midazolam; Ursodeoxycholic Acid | 2008 |
5 other study(ies) available for midazolam and ursodeoxycholic acid
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effect of ursodeoxycholic acid on the pharmacokinetics of midazolam and CYP3A in the liver and intestine of rats.
Topics: Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Half-Life; Hydroxylation; Injections, Intravenous; Intestinal Mucosa; Kinetics; Liver; Male; Membrane Proteins; Microsomes, Liver; Midazolam; Rats; Rats, Sprague-Dawley; RNA, Messenger; Ursodeoxycholic Acid | 2009 |
Evaluation of the pharmacokinetic interaction of midazolam with ursodeoxycholic acid, ketoconazole and dexamethasone by brain benzodiazepine receptor occupancy.
Topics: Administration, Oral; Animals; Brain; Cytochrome P-450 CYP3A; Dexamethasone; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; GABA Modulators; Ketoconazole; Male; Midazolam; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors; Ursodeoxycholic Acid | 2011 |
Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Behavior, Animal; beta-Cyclodextrins; Cats; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dietary Supplements; Humans; Intracellular Signaling Peptides and Proteins; Liver; Mass Spectrometry; Mice; Mice, Inbred BALB C; Mice, Knockout; Microsomes, Liver; Midazolam; Models, Animal; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Proteins; Real-Time Polymerase Chain Reaction; Ursodeoxycholic Acid | 2016 |