midazolam has been researched along with tadalafil in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faller, B; Trunzer, M; Zimmerlin, A | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bedding, AW; Eckstein, J; Forgue, ST; Gillespie, J; Jewell, H; Mitchell, MI; Patterson, BE; Payne, CD; Phillips, DL; Ring, BJ; Vandenbranden, M; Wrighton, SA | 1 |
| Burhenne, J; Carls, A; Haefeli, WE; Hohmann, N; Mikus, G; Reinhard, R; Schnaidt, S; Witt, L | 1 |
1 review(s) available for midazolam and tadalafil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for midazolam and tadalafil
| Article | Year |
|---|---|
Effect of tadalafil on cytochrome P450 3A4-mediated clearance: studies in vitro and in vivo.
Topics: Adult; Anti-Anxiety Agents; Anticholesteremic Agents; Area Under Curve; Carbolines; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Lovastatin; Male; Metabolic Clearance Rate; Microsomes, Liver; Midazolam; Middle Aged; Tadalafil | 2005 |
Treatment with rilpivirine does not alter plasma concentrations of the CYP3A substrates tadalafil and midazolam in humans.
Topics: Adolescent; Adult; Anti-HIV Agents; Cytochrome P-450 CYP3A; Drug Interactions; Female; Healthy Volunteers; Humans; Male; Midazolam; Middle Aged; Phosphodiesterase 5 Inhibitors; Plasma; Rilpivirine; Tadalafil; Young Adult | 2016 |
3 other study(ies) available for midazolam and tadalafil
| Article | Year |
|---|---|
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation.
Topics: Chromatography, Liquid; Drug Design; Humans; Likelihood Functions; Microsomes, Liver; Pharmacokinetics; Tandem Mass Spectrometry | 2009 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |