midazolam and propranolol

midazolam has been researched along with propranolol in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.00)18.7374
1990's3 (6.00)18.2507
2000's19 (38.00)29.6817
2010's23 (46.00)24.3611
2020's3 (6.00)2.80

Authors

AuthorsStudies
Coassolo, P; Lavé, T; Schneider, G1
Topliss, JG; Yoshida, F1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Jolivette, LJ; Nagilla, R; Ward, KW1
Abraham, MH; Acree, WE; Ibrahim, A1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Faller, B; Trunzer, M; Zimmerlin, A1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Obach, RS; Orozco, CC; Strelevitz, TJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barnard, L; Birkholtz, LM; Botha, M; Brunschwig, C; Burrows, JN; Chibale, K; Churchyard, A; Coetzer, TL; Denti, P; Egan, TJ; Laing, L; Lauterbach, S; Machado, M; Ndubi, F; Njogu, PM; Njoroge, M; Nondaba, S; Okombo, J; Prudêncio, M; Reader, J; Singh, K; Wiesner, L; Wilkinson, C; Wittlin, S; Yeates, C1
Chibale, K; Egan, TJ; Hunter, R; Joshi, MC; Ndove, J; Nsumiwa, S; Okombo, J; Taylor, D; Wiesner, L1
Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S1
Hu, J; Hu, Q; Kong, X; Liu, J; Luo, G; Shen, H; Wang, C; Wu, T; Wu, X; Xiang, Q; Xu, Y; Zhang, C; Zhang, Y; Zhuang, X; Zou, L1
Hashimoto, Y; Iwatsuki, N; Kato, M; Koga, Y; Sato, S; Sodeyama, N; Takahashi, M1
Bethea, CL; Lorens, SA; Paris, J; Richardson, KD; Urban, JH; Van de Kar, LD1
Chiba, S; Furukawa, Y; Ogiwara, Y; Saegusa, K; Takeda, M1
Crespi, CL; Davitt, CM; Hu, M; Huang, SM; Li, Y; Penman, BW; Thummel, K1
Franssila, S; Grigoras, K; Huikko, K; Kostiainen, R; Kotiaho, T; Mandel, F; Östman, P; Sauber, C1
Balani, SK; Gallegos, R; Gan, LS; Li, P; Lu, C; Miwa, GT; Uttamsingh, V; Xia, CQ1
Karlson-Stiber, C; Schmidt, A1
Bertoglio, LJ; Carobrez, AP; Stern, CA1
Carobrez, AP; Kroon, JA1
Inagaki, H; Kiyokawa, Y; Mori, Y; Takeuchi, Y1
Franklin, KB; Robinson, MJ1
Cvan Trobec, K; Kerec Kos, M; Lainscak, M; Springer, J; Trontelj, J1
Arakawa, H; Ikeya, T; Inoue, Y; Iwai, H; Jomura, T; Koeda, A; Kusumoto, K; Nagao, T; Naitoh, K; Ogihara, T; Ohkura, T; Ohta, K; Ozeki, E; Takahashi, N; Ueda, T; Wada, K1
Espejo, PJ; Giachero, M; Martijena, ID; Molina, VA; Ortiz, V1
Espejo, PJ; Martijena, ID; Molina, VA; Ortiz, V1
Armelin, VA; Braga, VHDS; Florindo, LH; Lopes, IG1
Hallifax, D; Houston, JB; Wood, FL1
Alfei, JM; Beckers, T; Luyten, L; Schnell, AE; Schroyens, N1
Gardner, I; Hatley, O; Jamei, M; Johnson, TN; Small, BG1

Reviews

1 review(s) available for midazolam and propranolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

49 other study(ies) available for midazolam and propranolol

ArticleYear
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
    Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25

    Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation.
    Journal of medicinal chemistry, 2009, Jan-22, Volume: 52, Issue:2

    Topics: Chromatography, Liquid; Drug Design; Humans; Likelihood Functions; Microsomes, Liver; Pharmacokinetics; Tandem Mass Spectrometry

2009
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:7

    Topics: Acetamides; Aldehyde Oxidase; Cryopreservation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Activation; Hepatocytes; Humans; Hydralazine; Liver; Microsomes, Liver; Pyrimidines

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model.
    Journal of medicinal chemistry, 2017, 02-23, Volume: 60, Issue:4

    Topics: Animals; Antimalarials; Benzimidazoles; Life Cycle Stages; Malaria; Male; Mice; Plasmodium berghei; Structure-Activity Relationship

2017
4-Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group Are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice.
    Journal of medicinal chemistry, 2017, 12-28, Volume: 60, Issue:24

    Topics: Administration, Oral; Aminopyridines; Aminoquinolines; Animals; Antimalarials; Cell Membrane Permeability; Chloroquine; CHO Cells; Cricetulus; Drug Evaluation, Preclinical; Drug Resistance, Microbial; ERG1 Potassium Channel; Hemeproteins; Humans; Malaria; Male; Mice, Inbred BALB C; Plasmodium berghei; Plasmodium falciparum; Solubility; Structure-Activity Relationship

2017
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
    European journal of medicinal chemistry, 2021, Nov-05, Volume: 223

    Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones

2021
Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer.
    Journal of medicinal chemistry, 2022, 01-13, Volume: 65, Issue:1

    Topics: Animals; Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; CREB-Binding Protein; Drug Design; Humans; Indolizidines; Male; Mice; Mice, SCID; Microsomes, Liver; Models, Molecular; Molecular Docking Simulation; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

2022
Comparison of the relaxant effects of diazepam, flunitrazepam and midazolam on airway smooth muscle.
    British journal of anaesthesia, 1992, Volume: 69, Issue:1

    Topics: Animals; Atropine; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Flunitrazepam; Guinea Pigs; Male; Midazolam; Muscle Relaxation; Muscle, Smooth; Propranolol; Trachea

1992
Pharmacological studies on stress-induced renin and prolactin secretion: effects of benzodiazepines, naloxone, propranolol and diisopropyl fluorophosphate.
    Brain research, 1985, Oct-21, Volume: 345, Issue:2

    Topics: Animals; Benzodiazepines; Chlordiazepoxide; Isoflurophate; Juxtaglomerular Apparatus; Male; Midazolam; Naloxone; Pituitary Gland, Anterior; Prolactin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, GABA-A; Renin; Stress, Psychological

1985
Pharmacologic basis of responses to midazolam in the isolated, cross-perfused, canine right atrium.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:8

    Topics: Animals; Atropine; Benzodiazepinones; Blood Donors; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Heart Atria; Heart Rate; Imipramine; In Vitro Techniques; Midazolam; Myocardial Contraction; Propranolol; Sympathetic Nervous System; Tetrodotoxin

1987
Transport and metabolic characterization of Caco-2 cells expressing CYP3A4 and CYP3A4 plus oxidoreductase.
    Pharmaceutical research, 1999, Volume: 16, Issue:9

    Topics: Anticoagulants; Antineoplastic Agents, Hormonal; Biological Transport; Caco-2 Cells; Calcium Channel Blockers; Carcinogens; Cell Division; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diuretics, Osmotic; GABA Modulators; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Indoles; Mammary Tumor Virus, Mouse; Mannitol; Microscopy, Electron; Microsomes; Midazolam; Mixed Function Oxygenases; Nifedipine; Oxidoreductases; Propranolol; Pyridines; Sympatholytics; Testosterone; Tetradecanoylphorbol Acetate; Transfection; Tritium; Warfarin

1999
Feasibility of atmospheric pressure desorption/ionization on silicon mass spectrometry in analysis of drugs.
    Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:12

    Topics: Acetaminophen; Air Ionization; Atmospheric Pressure; Carboxylic Acids; Ketoprofen; Mass Spectrometry; Midazolam; Molecular Structure; Naphthaleneacetic Acids; Naphthalenes; Naphthoquinones; Pharmaceutical Preparations; Propranolol; Silicon; Testosterone

2003
Comparison of intrinsic clearance in liver microsomes and hepatocytes from rats and humans: evaluation of free fraction and uptake in hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:9

    Topics: Animals; Biological Transport; Coumarins; Cryopreservation; Diffusion; Drug Evaluation, Preclinical; Hepatocytes; Humans; In Vitro Techniques; Kinetics; Metabolic Clearance Rate; Microsomes, Liver; Midazolam; Phenacetin; Propranolol; Rats; Reproducibility of Results

2006
Caffeine poisoning and lactate rise: an overlooked toxic effect?
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antidotes; Anxiety; Caffeine; Central Nervous System Stimulants; Charcoal; Female; Gastric Lavage; Humans; Hypokalemia; Lactic Acid; Midazolam; Ondansetron; Propranolol; Rare Diseases; Severity of Illness Index; Suicide, Attempted; Treatment Outcome

2008
Aversive learning as a mechanism for lack of repeated anxiolytic-like effect in the elevated plus-maze.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Dose-Response Relationship, Drug; Learning; Male; Midazolam; Propranolol; Rats; Rats, Wistar

2008
Olfactory fear conditioning paradigm in rats: effects of midazolam, propranolol or scopolamine.
    Neurobiology of learning and memory, 2009, Volume: 91, Issue:1

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Avoidance Learning; Coffee; Conditioning, Classical; Electroshock; Escape Reaction; Fear; Male; Midazolam; Odorants; Propranolol; Rats; Rats, Wistar; Scopolamine; Smell

2009
The alarm pheromone in male rats as a unique anxiety model: psychopharmacological evidence using anxiolytics.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 94, Issue:4

    Topics: Administration, Inhalation; Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Clonidine; Disease Models, Animal; Male; Midazolam; Phenelzine; Pheromones; Propranolol; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Reflex, Startle

2010
Reconsolidation of a morphine place preference: impact of the strength and age of memory on disruption by propranolol and midazolam.
    Behavioural brain research, 2010, Dec-01, Volume: 213, Issue:2

    Topics: Amnesia; Animals; Choice Behavior; Conditioning, Psychological; Drug Synergism; Male; Memory; Midazolam; Morphine; Propranolol; Rats; Time Factors

2010
Liquid chromatography-tandem mass spectrometry method for simultaneous quantification of bisoprolol, ramiprilat, propranolol and midazolam in rat dried blood spots.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, May-01, Volume: 958

    Topics: Animals; Antihypertensive Agents; Bisoprolol; Chromatography, Liquid; Dried Blood Spot Testing; Hypnotics and Sedatives; Limit of Detection; Male; Midazolam; Propranolol; Ramipril; Rats; Rats, Wistar; Tandem Mass Spectrometry

2014
Evaluation of human hepatocytes cultured by three-dimensional spheroid systems for drug metabolism.
    Drug metabolism and pharmacokinetics, 2014, Volume: 29, Issue:5

    Topics: Acetaminophen; Albuterol; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Diclofenac; Glucuronosyltransferase; Hepatocytes; Humans; Lamotrigine; Midazolam; Pharmaceutical Preparations; Propranolol; Spheroids, Cellular; Tandem Mass Spectrometry; Triazines

2014
The effect of Midazolam and Propranolol on fear memory reconsolidation in ethanol-withdrawn rats: influence of d-cycloserine.
    The international journal of neuropsychopharmacology, 2015, Jan-23, Volume: 18, Issue:4

    Topics: Amygdala; Animals; Anti-Anxiety Agents; Central Nervous System Depressants; Conditioning, Psychological; Cycloserine; Disease Models, Animal; Ethanol; Excitatory Amino Acid Agents; Fear; Male; Memory; Midazolam; Propranolol; Random Allocation; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome

2015
GABAergic signaling within the Basolateral Amygdala Complex modulates resistance to the labilization/reconsolidation process.
    Neurobiology of learning and memory, 2017, Volume: 144

    Topics: Adrenergic beta-Antagonists; Animals; Avoidance Learning; Basolateral Nuclear Complex; Fear; GABA Modulators; gamma-Aminobutyric Acid; Male; Memory Consolidation; Mental Recall; Midazolam; Propranolol; Rats, Wistar; Stress, Psychological

2017
The influence of midazolam on heart rate arises from cardiac autonomic tones alterations in Burmese pythons, Python molurus.
    Autonomic neuroscience : basic & clinical, 2017, Volume: 208

    Topics: Animals; Atropine; Autonomic Nervous System; Boidae; Bradycardia; Cardiovascular Agents; Electrocardiography; GABA Modulators; Heart; Heart Rate; Hypnotics and Sedatives; Midazolam; Propranolol

2017
Importance of the Unstirred Water Layer and Hepatocyte Membrane Integrity In Vitro for Quantification of Intrinsic Metabolic Clearance.
    Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:3

    Topics: Animals; Biological Transport; Cell Membrane Permeability; Cytochrome P-450 Enzyme System; Hepatocytes; Kinetics; Liver; Male; Metabolic Clearance Rate; Midazolam; NADP; Propranolol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Saquinavir; Water

2018
Limited replicability of drug-induced amnesia after contextual fear memory retrieval in rats.
    Neurobiology of learning and memory, 2019, Volume: 166

    Topics: Amnesia; Animals; Conditioning, Psychological; Fear; Hypnotics and Sedatives; Mental Recall; Midazolam; Propranolol; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reproducibility of Results

2019
Incorporation and Performance Verification of Hepatic Portal Blood Flow Shunting in Minimal and Full PBPK Models of Liver Cirrhosis.
    Clinical pharmacology and therapeutics, 2023, Volume: 114, Issue:6

    Topics: Buspirone; Humans; Liver Cirrhosis; Midazolam; Models, Biological; Propranolol; Simvastatin

2023