midazolam has been researched along with naloxone in 72 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (6.94) | 18.7374 |
| 1990's | 30 (41.67) | 18.2507 |
| 2000's | 21 (29.17) | 29.6817 |
| 2010's | 15 (20.83) | 24.3611 |
| 2020's | 1 (1.39) | 2.80 |
| Authors | Studies |
|---|---|
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Obach, RS; Orozco, CC; Strelevitz, TJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gillis, RA; Pineo, S; Taveira Da Silva, AM | 1 |
| Holdcroft, A; Nicol, ME | 1 |
| Chakrabarti, MK; Galletly, DC; Wang, C; Whitwam, JG | 1 |
| Fuji, K; Miyamoto, K; Okuda, T; Suekane, K; Wakita, K | 1 |
| McDonald, JS; Rattan, AK; Tejwani, GA | 1 |
| Greeley, JD; Nabke, CP; Swinbourne, AL; Westbrook, RF | 1 |
| Gent, JP; Goodchild, CS; Serrao, JM | 1 |
| Archdeacon, J; Brimacombe, J; Martin, J; Newell, S | 1 |
| Conci, F; Ferrario, P; Hafner, B; Mantegazza, P; Tammiso, R; Zambotti, F; Zecca, L; Zonta, N | 1 |
| Kaniaris, PK; Sarlis, NJ | 1 |
| Lenz, K; Loimer, N; Presslich, O; Schmid, R | 1 |
| Charlton, D; Herbeau, C; Renouard, F | 1 |
| Sabbe, MB; Stevens, CW; Yaksh, TL; Yanez, A | 1 |
| Hall, RI; Hug, CC; Schwieger, IM; Szlam, F | 1 |
| Bergman, SA; Coro, C; Hyatt, J; Wynn, RL | 1 |
| Bethea, CL; Lorens, SA; Paris, J; Richardson, KD; Urban, JH; Van de Kar, LD | 1 |
| Davidovich, S; Geller, E; Niv, D; Urca, G | 1 |
| Bachmann, M; Forster, A; Gemperle, M; Morel, D | 1 |
| Hayashi, T; Hill, HF; Lorenz, IH; Luger, TJ | 1 |
| Harris, JA; Westbrook, RF | 1 |
| Harris, JA; McGregor, IS; Westbrook, RF | 1 |
| Fujimoto, JM; Rady, JJ | 1 |
| Jeske, AH; Redden, RJ | 1 |
| Rattan, AK; Tejwani, GA | 1 |
| Brandão, ML; Motta, V | 1 |
| Chaudhry, H; Hofmann, P; Loimer, N | 1 |
| Brill, T; Erhardt, W; Henke, J; Lendl, C; Matis, U; Otto, K; Roberts, U | 1 |
| Cooper, SJ; Higgs, S | 1 |
| Brandon, MJ; Geiger, MJ; Kearney, MM; Kent, V; Natale, A; Newby, KH; Wase, A | 1 |
| Hesselbjerg, L; Koscielniak-Nielsen, ZJ; Stens-Pedersen, HL | 1 |
| Collins, PD; Cook, TM | 1 |
| Murata, Y | 1 |
| Büttner, T; Dworzak, H; Fuss, F | 1 |
| DeMaria, PA; Kane, HL; Reining, KM; Wilson, LB | 1 |
| Canto-de-Souza, A; da-Costa, M; Fornari, RV; Graeff, FG; Nunes-de-Souza, RL; Pelá, IR | 1 |
| Garman, RH; Kofke, WA; Sinz, EH | 1 |
| Bredas, P; Clement, B; Dan, B; Pelc, I; Streel, E; Verbanck, P | 1 |
| Cao, JL; Ding, HL; Duan, SM; Zeng, YM; Zhang, LC | 1 |
| Barichello, T; de-Paris, F; Kapczinski, F; Quevedo, J; Roesler, R; Vianna, MR | 1 |
| Dehne, MG; Engel, J; Fuchs, M; Gonter, J; Hempelmann, G; Krüll, M; Matejec, R; Menges, T; Mühling, J; Nickolaus, KA; Sablotzki, A; Welters, ID; Wolff, M | 1 |
| Abadie, C; Alexandre, E; Blanchard, N; Coassolo, P; Heyd, B; Jaeck, D; Lavé, T; Mantion, G; Richert, L | 1 |
| Cohen, S; Hijazi, RH; Hunter, CW; Striker, P; Yanni, B | 1 |
| Collier, CB | 1 |
| Kelly, L | 1 |
| Darnell, CM; Roy, L; Sheeran, P; Stromberg, D; Thompson, J | 1 |
| Asl, BH; Hassanzadeh, K; Khezri, E; Mohammadi, S | 1 |
| Béchir, M; Keel, M; Meierhans, R; Stocker, R; Stover, JF | 1 |
| Creighton, P; Heard, C; Lerman, J | 1 |
| Facco, E; Favero, L; Manani, G; Zanette, G | 1 |
| Gerónimo Pardo, M; Mateo Cerdán, CM; Moreno Salcedo, JM | 1 |
| Kanmura, Y; Moriyama, T; Tsuneyoshi, I | 1 |
| Barnett, S; Falchuk, ZM; Hung, A; Leffler, DA; Marshall, J; Sawhney, M | 1 |
| Haefeli, WE; König, SK; Mahlke, NS; Mikus, G; Skopp, G; Ziesenitz, VC | 1 |
| Arras, M; Cesarovic, N; Fleischmann, T; Henke, J; Jirkof, P | 1 |
| Shimura, T; Yasoshima, Y | 1 |
| Bailey, AM; Baum, RA; Horn, K; Justice, SN; Lewis, T; Morizio, K; Schultz, A; Weant, K | 1 |
| Barbas, B; Chaney, W; Greenhalgh, E; Rech, MA; Turck, C | 1 |
| Naranjo, J; Pollard, EM; Sprung, J; Warner, MA; Warner, ME; Weingarten, TN | 1 |
| Albrecht, R; Hautz, WE; Josi, D; Jungwirth, A; Koppenberg, J; Moeckel, J; Pietsch, U; Strecke, S; Wenzel, V | 1 |
6 review(s) available for midazolam and naloxone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Narcotic/sedative receptor antagonists.
Topics: Anesthesia, Dental; Anti-Anxiety Agents; Binding, Competitive; Conscious Sedation; Drug Interactions; Emergencies; Flumazenil; Humans; Midazolam; Naloxone; Narcotic Antagonists; Receptors, GABA-A; Receptors, Opioid | 1993 |
Anesthesia-assisted rapid opiate detoxification: a new procedure in the postanesthesia care unit.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Heroin Dependence; Humans; Male; Midazolam; Naloxone; Narcotic Antagonists; Perioperative Care; Postanesthesia Nursing; Propofol; Substance Withdrawal Syndrome | 1999 |
The occasional shoulder reduction.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Female; Fentanyl; Humans; Male; Manipulation, Orthopedic; Midazolam; Naloxone; Narcotic Antagonists; Physical Examination; Radiography; Shoulder Dislocation; Supine Position; Treatment Outcome | 2007 |
Review of Intranasally Administered Medications for Use in the Emergency Department.
Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics | 2017 |
When to Pick the Nose: Out-of-Hospital and Emergency Department Intranasal Administration of Medications.
Topics: Administration, Intranasal; Analgesics, Opioid; Conscious Sedation; Dexmedetomidine; Drug Overdose; Emergency Service, Hospital; Fentanyl; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Naloxone; Patient Safety; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Treatment Outcome; Wounds and Injuries | 2017 |
5 trial(s) available for midazolam and naloxone
| Article | Year |
|---|---|
Respiratory depressant effects of different doses of midazolam and lack of reversal with naloxone--a double-blind randomized study.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Depression, Chemical; Dose-Response Relationship, Drug; Double-Blind Method; Hemodynamics; Humans; Male; Midazolam; Naloxone; Random Allocation; Respiration; Tidal Volume | 1983 |
Midazolam-flumazenil versus propofol anaesthesia for scoliosis surgery with wake-up tests.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Antidotes; Arousal; Child; Drug Costs; Evoked Potentials, Somatosensory; Female; Flumazenil; Humans; Intraoperative Care; Intubation, Intratracheal; Male; Memory; Midazolam; Monitoring, Intraoperative; Naloxone; Narcotic Antagonists; Pain; Postoperative Care; Propofol; Prospective Studies; Psychomotor Performance; Scoliosis; Spinal Cord; Wakefulness | 1998 |
Effect of low-dose naloxone infusion on fentanyl requirements in critically ill children.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Conscious Sedation; Critical Illness; Double-Blind Method; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infusions, Intravenous; Intensive Care Units, Pediatric; Male; Midazolam; Naloxone; Narcotic Antagonists; Respiration, Artificial; Substance Withdrawal Syndrome | 2008 |
Pharmacokinetic interaction of intravenous fentanyl with ketoconazole.
Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Fentanyl; Healthy Volunteers; Humans; Ketoconazole; Male; Midazolam; Middle Aged; Naloxone; Prospective Studies; Tandem Mass Spectrometry; Young Adult | 2015 |
Injection anaesthesia with fentanyl-midazolam-medetomidine in adult female mice: importance of antagonization and perioperative care.
Topics: Analgesics; Anesthetics, Combined; Animals; Body Temperature; Female; Fentanyl; Flumazenil; Heart Rate; Imidazoles; Injections, Intraperitoneal; Medetomidine; Mice; Mice, Inbred C57BL; Midazolam; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Perioperative Care | 2016 |
61 other study(ies) available for midazolam and naloxone
| Article | Year |
|---|---|
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance.
Topics: Acetamides; Aldehyde Oxidase; Cryopreservation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Activation; Hepatocytes; Humans; Hydralazine; Liver; Microsomes, Liver; Pyrimidines | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Gamma-aminobutyric acid type A receptor blockade at the intermediate area of the ventral surface of the medulla counteracts the cardiorespiratory depression produced by intravenous midazolam.
Topics: Animals; Bicuculline; Cardiovascular System; Cats; GABA-A Receptor Antagonists; Medulla Oblongata; Midazolam; Morphine; Naloxone; Pentobarbital; Respiratory System | 1992 |
Density of intrathecal agents.
Topics: Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Baclofen; Body Temperature; Cerebrospinal Fluid; Clonidine; Droperidol; Humans; Methadone; Midazolam; Naloxone; Specific Gravity; Temperature | 1992 |
Relative effects of intrathecal administration of fentanyl and midazolam on A delta and C fibre reflexes.
Topics: Anesthesia, Spinal; Animals; Dogs; Electric Stimulation; Fentanyl; Flumazenil; Kidney; Midazolam; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Reflex; Sympathetic Nervous System; Tibial Nerve | 1992 |
Suppressant effects of midazolam on responses of spinal dorsal horn neurones in rabbits.
Topics: Animals; Bradykinin; Decerebrate State; Flunitrazepam; Microelectrodes; Midazolam; Naloxone; Neurons; Pain; Rabbits; Spinal Cord | 1992 |
Differential effects of intrathecal midazolam on morphine-induced antinociception in the rat: role of spinal opioid receptors.
Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Injections, Spinal; Male; Midazolam; Morphine; Naloxone; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord | 1991 |
Aversive conditioning in the rat: effects of a benzodiazepine and of an opioid agonist and antagonist on conditioned hypoalgesia and fear.
Topics: Animals; Arousal; Avoidance Learning; Brain; Conditioning, Classical; Dose-Response Relationship, Drug; Fear; Male; Midazolam; Morphine; Naloxone; Nociceptors; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Receptors, Opioid; Sensory Thresholds; Thermosensing | 1991 |
Reversal by naloxone of spinal antinociceptive effects of fentanyl, ketocyclazocine and midazolam.
Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Ethylketocyclazocine; Fentanyl; Flumazenil; Injections, Spinal; Lumbar Vertebrae; Male; Midazolam; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Sensory Thresholds | 1991 |
Two cases of naloxone-induced pulmonary oedema--the possible use of phentolamine in management.
Topics: Adolescent; Aged; Bronchial Spasm; Furosemide; Humans; Hydrocortisone; Male; Midazolam; Naloxone; Phentolamine; Pulmonary Edema; Succinylcholine | 1991 |
Effects of diazepam on nociception in rats.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Benzomorphans; Chlordiazepoxide; Convulsants; Diazepam; Drug Interactions; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Midazolam; Muscimol; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Physostigmine is equipotent to flumazenil only in excessive doses, while naloxone is ineffective in reversing midazolam anesthesia.
Topics: Animals; Flumazenil; Male; Midazolam; Naloxone; Physostigmine; Rats; Rats, Inbred Strains | 1991 |
Technique for greatly shortening the transition from methadone to naltrexone maintenance of patients addicted to opiates.
Topics: Adult; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Methadone; Midazolam; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1991 |
[Ambulatory vigil anesthesia for implant surgery].
Topics: Alfentanil; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, Intravenous; Dental Implantation, Endosseous; Drug Therapy, Combination; Female; Humans; Male; Midazolam; Middle Aged; Monitoring, Intraoperative; Naloxone; Periodontium | 1991 |
Interaction of midazolam and morphine in the spinal cord of the rat.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electromyography; Flumazenil; Injections, Spinal; Male; Midazolam; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Spinal Cord | 1990 |
Anesthetic interactions of midazolam and fentanyl: is there acute tolerance to the opioid?
Topics: Anesthesia, Inhalation; Animals; Dogs; Drug Interactions; Enflurane; Fentanyl; Flumazenil; Male; Midazolam; Naloxone; Pulmonary Alveoli; Respiration | 1989 |
Effects of midazolam on fentanyl antinociception and respiration in a rabbit model.
Topics: Analgesics; Animals; Carbon Dioxide; Drug Combinations; Electric Stimulation; Female; Fentanyl; Infusions, Intravenous; Male; Midazolam; Naloxone; Rabbits; Respiration; Respiratory Insufficiency | 1989 |
Pharmacological studies on stress-induced renin and prolactin secretion: effects of benzodiazepines, naloxone, propranolol and diisopropyl fluorophosphate.
Topics: Animals; Benzodiazepines; Chlordiazepoxide; Isoflurophate; Juxtaglomerular Apparatus; Male; Midazolam; Naloxone; Pituitary Gland, Anterior; Prolactin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, GABA-A; Renin; Stress, Psychological | 1985 |
RO 15-1788 produces naloxone-reversible analgesia in the rat.
Topics: Analgesics; Animals; Flumazenil; Injections, Intraperitoneal; Injections, Intraventricular; Male; Midazolam; Naloxone; Pain; Rats | 1988 |
Mechanisms of the influence of midazolam on morphine antinociception at spinal and supraspinal levels in rats.
Topics: Analgesia; Animals; Drug Interactions; Flumazenil; Injections, Intraventricular; Male; Midazolam; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Reaction Time; Spinal Cord | 1994 |
Effects of midazolam and naloxone in rats tested for sensitivity/reactivity to formalin pain in a familiar, novel or aversively conditioned environment.
Topics: Analgesia; Animals; Conditioning, Operant; Conditioning, Psychological; Environment; Extinction, Psychological; Flumazenil; Formaldehyde; Male; Midazolam; Naloxone; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Reinforcement, Psychology | 1994 |
Low and high doses of midazolam differentially affect hypoalgesia in rats conditioned to a heat stressor.
Topics: Analgesia; Animals; Behavior, Animal; Conditioning, Psychological; Dose-Response Relationship, Drug; Fear; Flumazenil; Hot Temperature; Male; Midazolam; Naloxone; Pain Measurement; Rats; Rats, Wistar; Stress, Psychological | 1993 |
Dynorphin A(1-17) mediates midazolam antagonism of morphine antinociception in mice.
Topics: Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Dynorphins; GABA Antagonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Midazolam; Morphine; Naloxone; Naltrexone; Pain Measurement; Reaction Time; Spinal Cord | 1993 |
Sodium ions modulate differentially the effect of a benzodiazepine agonist on rat spinal mu-, delta- and kappa-opioid receptors.
Topics: Animals; Enkephalins; Ligands; Male; Midazolam; Naloxone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium; Spinal Cord | 1994 |
Aversive and antiaversive effects of morphine in the dorsal periaqueductal gray of rats submitted to the elevated plus-maze test.
Topics: Animals; Anxiety; Dose-Response Relationship, Drug; Electrodes; Exploratory Behavior; Male; Microinjections; Midazolam; Morphine; Naloxone; Periaqueductal Gray; Rats; Rats, Wistar; Reinforcement, Psychology | 1993 |
Ultrashort noninvasive opiate detoxification.
Topics: Adult; Heroin Dependence; Humans; Male; Midazolam; Naloxone; Naltrexone; Ondansetron; Substance Withdrawal Syndrome; Time Factors | 1993 |
[Clinical investigations of an i.m. combination anesthesia with fentanylclimazolam/xylazine and postoperative i.v. antagonism with naloxone/sarmazenil/yohimbine in guinea pigs].
Topics: Anesthesia, General; Anesthetics, Intravenous; Animals; Anti-Anxiety Agents; Benzodiazepines; Drug Combinations; Female; Fentanyl; Guinea Pigs; Imidazoles; Injections, Intramuscular; Injections, Intravenous; Male; Midazolam; Naloxone; Narcotic Antagonists; Xylazine; Yohimbine | 1996 |
Midazolam-induced rapid changes in licking behaviour: evidence for involvement of endogenous opioid peptides.
Topics: Animals; Drug Interactions; Feeding Behavior; Flumazenil; Male; Midazolam; Naloxone; Opioid Peptides; Rats | 1997 |
Evaluation of the safety and efficacy of deep sedation for electrophysiology procedures administered in the absence of an anesthetist.
Topics: Adjuvants, Anesthesia; Airway Obstruction; Anesthesia, Intravenous; Anesthesiology; Anesthetics, Intravenous; Blood Pressure; Consciousness; Cost Control; Electrocardiography; Electrophysiology; Evaluation Studies as Topic; Female; Fentanyl; Heart Rate; Humans; Hypnotics and Sedatives; Hypotension; Laboratories; Length of Stay; Male; Memory; Meperidine; Midazolam; Middle Aged; Monitoring, Physiologic; Naloxone; Narcotic Antagonists; Oximetry; Oxygen; Promethazine; Safety | 1997 |
Rapid opioid detoxification under anaesthesia.
Topics: Adult; Anesthesia, General; Atracurium; Drug Therapy, Combination; Follow-Up Studies; Gastrointestinal Agents; Humans; Hypnotics and Sedatives; Male; Midazolam; Naloxone; Naltrexone; Narcotic Antagonists; Nicotinic Antagonists; Octreotide; Opioid-Related Disorders; Propofol | 1998 |
[Effects of anesthetics on somatosensory evoked potentials by median nerve stimulation in human--analyses after single administration in volunteers].
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Electric Stimulation; Evoked Potentials, Somatosensory; Flumazenil; Humans; Male; Median Nerve; Midazolam; Naloxone; Nitrous Oxide; Propofol; Reaction Time; Thiopental | 1998 |
[Persisting respiratory depression following intrathecal administration of morphine and simultaneous sedation with midazolam].
Topics: Aged; Analgesics, Opioid; Flumazenil; Humans; Hypnotics and Sedatives; Injections, Spinal; Intubation, Intratracheal; Male; Midazolam; Morphine; Naloxone; Narcotic Antagonists; Respiration, Artificial; Respiratory Insufficiency | 1999 |
Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Analgesia; Animals; Anti-Anxiety Agents; Anxiety; Male; Mice; Microinjections; Midazolam; Naloxone; Narcotic Antagonists; Pain Measurement; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Phenytoin, midazolam, and naloxone protect against fentanyl-induced brain damage in rats.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Blood Gas Analysis; Body Weight; Brain Diseases; Electroencephalography; Fentanyl; GABA Modulators; Male; Midazolam; Naloxone; Narcotic Antagonists; Phenytoin; Rats; Rats, Sprague-Dawley | 2000 |
Interference with withdrawal signs of naloxone-induced opiate withdrawal under anesthesia is anesthetic-specific in opiate-dependent rats.
Topics: Anesthesia, General; Anesthetics, Dissociative; Animals; Defecation; Dose-Response Relationship, Drug; Drug Interactions; Ketamine; Male; Midazolam; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Urination | 2001 |
Pretreatment with midazolam suppresses morphine withdrawal response in mice and rats.
Topics: Adenosine Monophosphate; Animals; Anti-Anxiety Agents; Mice; Midazolam; Morphine Dependence; Naloxone; Oncogene Proteins v-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance Withdrawal Syndrome | 2002 |
Interaction between midazolam-induced anterograde amnesia and memory enhancement by treatments given immediately after training on an inhibitory avoidance task in rats.
Topics: Amnesia, Anterograde; Animals; Avoidance Learning; Dexamethasone; Epinephrine; Female; GABA Modulators; Glucose; Memory; Midazolam; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar | 2002 |
Benzodiazepine receptor-dependent modulation of neutrophil (PMN) free amino- and alpha-keto acid profiles or immune functions.
Topics: Adult; Amino Acids; Benzodiazepinones; Cells, Cultured; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Hydrogen Peroxide; Isoquinolines; Keto Acids; Male; Midazolam; Naloxone; Neutrophils; Peroxidase; Receptors, GABA-A; Superoxides | 2005 |
Comparison of clearance predictions using primary cultures and suspensions of human hepatocytes.
Topics: Algorithms; Bosentan; Cell Culture Techniques; Cells, Cultured; Computer Simulation; Cryopreservation; Hepatocytes; Humans; Midazolam; Models, Biological; Naloxone; Sulfonamides | 2005 |
Central anticholinergic syndrome strikes again.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, General; Anesthetics, Intravenous; Central Nervous System Diseases; Cholinesterase Inhibitors; Electrocardiography; Female; Glucose; Glycopyrrolate; Heart Block; Heart Rate; Humans; Midazolam; Middle Aged; Naloxone; Narcotic Antagonists; Physostigmine; Propofol; Respiration, Artificial; Syndrome | 2006 |
Unplanned 'unconsciousness' at Caesarean section: hysteria or drug reaction?
Topics: Adult; Amides; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthetics, Intravenous; Anesthetics, Local; Antidotes; Blood Pressure; Central Nervous System Stimulants; Cesarean Section; Diagnosis, Differential; Elective Surgical Procedures; Ephedrine; Female; Flumazenil; Humans; Hysteria; Meperidine; Midazolam; Naloxone; Narcotic Antagonists; Pregnancy; Ropivacaine; Unconsciousness | 2007 |
Evaluation the effects of dextromethorphan and midazolam on morphine induced tolerance and dependence in mice.
Topics: Animals; Dextromethorphan; Drug Tolerance; Male; Mice; Midazolam; Morphine; Naloxone; Substance-Related Disorders | 2008 |
Reduced midazolam clearance must be considered in prolonged coma.
Topics: Adult; Anesthetics, Intravenous; Antidotes; Cholinesterase Inhibitors; Coma; Flumazenil; Humans; Male; Metabolic Clearance Rate; Midazolam; Naloxone; Narcotic Antagonists; Physostigmine; Time | 2008 |
Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations.
Topics: Adjuvants, Anesthesia; Administration, Intranasal; Anesthesia, Dental; Antidotes; Child, Preschool; Dental Restoration, Temporary; Female; Flumazenil; Humans; Laryngismus; Midazolam; Naloxone; Narcotic Antagonists; Oxygen; Sufentanil; Treatment Outcome | 2009 |
Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations: comment.
Topics: Administration, Intranasal; Antidotes; Child; Child Behavior; Conscious Sedation; Deep Sedation; Dental Restoration, Permanent; Flumazenil; Humans; Hypnotics and Sedatives; Midazolam; Naloxone; Narcotic Antagonists | 2010 |
[Transient decerebrate rigidity from hypoxemia during administration of propofol, midazolam-flumazenil, and remifentanil-naloxone].
Topics: Airway Obstruction; Anesthetics, Intravenous; Bradycardia; Cardiotonic Agents; Cholangiopancreatography, Endoscopic Retrograde; Choledocholithiasis; Decerebrate State; Flumazenil; GABA Agonists; Humans; Hypnotics and Sedatives; Hypoxia; Intraoperative Complications; Intubation, Intratracheal; Male; Midazolam; Middle Aged; Naloxone; Piperidines; Propofol; Remifentanil; Sleep Apnea, Obstructive | 2010 |
Effects of a novel benzodiazepine derivative, JM-1232(-), on human gastroepiploic artery in vitro.
Topics: Dose-Response Relationship, Drug; Endothelium, Vascular; Flumazenil; GABA Modulators; Gastroepiploic Artery; Humans; In Vitro Techniques; Isoindoles; Midazolam; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Narcotic Antagonists; Norepinephrine; Piperazines; Potassium; Propofol; Structure-Activity Relationship; Vasoconstrictor Agents | 2011 |
Risk Factors and Outcomes of Reversal Agent Use in Moderate Sedation During Endoscopy and Colonoscopy.
Topics: Age Factors; Anti-Arrhythmia Agents; Antidotes; Atropine; Body Mass Index; Bradycardia; Case-Control Studies; Colonoscopy; Conscious Sedation; Female; Fentanyl; Flumazenil; Health Status; Humans; Hypnotics and Sedatives; Hypotension; Hypoxia; Male; Midazolam; Middle Aged; Naloxone; Narcotic Antagonists; Sex Factors; Treatment Outcome | 2016 |
Midazolam impairs the retrieval of conditioned taste aversion via opioidergic transmission in mice.
Topics: Animals; Avoidance Learning; Conditioning, Classical; Eating; Male; Mice, Inbred C57BL; Midazolam; Naloxone; Narcotic Antagonists; Receptors, Opioid; Taste | 2017 |
Serotonergic medications, herbal supplements, and perioperative serotonin syndrome.
Topics: Aged; Curcuma; Dietary Supplements; Drug Interactions; Fentanyl; Fluoxetine; Humans; Male; Midazolam; Naloxone; Perioperative Period; Serotonin Agents; Serotonin Syndrome; Time Factors; Trazodone; Young Adult | 2017 |
Stability of Drugs Stored in Helicopters for Use by Emergency Medical Services: A Prospective Observational Study.
Topics: Aircraft; Amiodarone; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Emergency Medical Services; Epinephrine; Etomidate; Fentanyl; Humans; Ketamine; Longitudinal Studies; Midazolam; Naloxone; Norepinephrine; Prospective Studies; Rocuronium; Temperature | 2022 |