Compounds > midazolam

midazolam and nadp

midazolam has been researched along with nadp in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benet, LZ; Jang, GR1
Hall, SD; Mäenpää, J; Ring, BJ; Strom, SC; Wrighton, SA1
Fujita, K; Kamataki, T; Nakayama, K; Nohmi, T; Tsuruma, K; Yamada, M; Yamazaki, Y1
Blain, PG; Daly, AK; Leathart, JB; Mutch, E; Williams, FM1
Fan, PW; Henne, KR; Johnson, MG; Subramanian, R; Tadano Lohr, M; Tonn, GR; Wong, BK; Wong, SG1
Chan, EC; Chua, TB; Ho, HK; Nelson, SD; New, LS; Yap, CW1
Chapron, B; Collins, C; Phillips, B; Risler, L; Shen, D; Thummel, K1
Hallifax, D; Houston, JB; Wood, FL1

Other Studies

8 other study(ies) available for midazolam and nadp

ArticleYear
Antiprogestin-mediated inactivation of cytochrome P450 3A4.
    Pharmacology, 1998, Volume: 56, Issue:3

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estrenes; Gonanes; Hormone Antagonists; Humans; Microsomes, Liver; Midazolam; Mifepristone; Mixed Function Oxygenases; NADP; Spectrophotometry; Tissue Donors

1998
Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone.
    Pharmacogenetics, 1998, Volume: 8, Issue:2

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Benzene Derivatives; Benzoflavones; Buffers; Calcium Chloride; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Magnesium Chloride; Microsomes, Liver; Midazolam; NADP; Oxidoreductases, N-Demethylating; Terfenadine; Testosterone

1998
Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase.
    Environmental and molecular mutagenesis, 2001, Volume: 38, Issue:4

    Topics: Alkylating Agents; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diclofenac; Ethanolamines; Genetic Engineering; Humans; Midazolam; Mixed Function Oxygenases; Mutagenicity Tests; NADP; NADPH-Ferrihemoprotein Reductase; Nitrosamines; Recombinant Proteins; Salmonella typhimurium; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

2001
Do multiple cytochrome P450 isoforms contribute to parathion metabolism in man?
    Archives of toxicology, 2003, Volume: 77, Issue:6

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Insecta; Mephenytoin; Microsomes, Liver; Midazolam; NADP; Nifedipine; Nitrophenols; Paclitaxel; Paraoxon; Parathion; Testosterone

2003
Bioactivation of a novel 2-methylindole-containing dual chemoattractant receptor-homologous molecule expressed on T-helper type-2 cells/D-prostanoid receptor antagonist leads to mechanism-based CYP3A inactivation: glutathione adduct characterization and p
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:5

    Topics: Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biocatalysis; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Glutathione; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Indinavir; Indoles; Kinetics; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Microsomes, Liver; Midazolam; Models, Biological; Molecular Structure; NADP; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Tandem Mass Spectrometry

2010
Interaction of lapatinib with cytochrome P450 3A5.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:7

    Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dealkylation; Humans; Hydroxylation; Lapatinib; Midazolam; NADP; Protein Kinase Inhibitors; Quinazolines; Testosterone

2012
Reversible, time-dependent inhibition of CYP3A-mediated metabolism of midazolam and tacrolimus by telaprevir in human liver microsomes.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2015, Volume: 18, Issue:1

    Topics: Antiviral Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Immunosuppressive Agents; Inhibitory Concentration 50; Microsomes, Liver; Midazolam; NADP; Oligopeptides; Tacrolimus; Time Factors

2015
Importance of the Unstirred Water Layer and Hepatocyte Membrane Integrity In Vitro for Quantification of Intrinsic Metabolic Clearance.
    Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:3

    Topics: Animals; Biological Transport; Cell Membrane Permeability; Cytochrome P-450 Enzyme System; Hepatocytes; Kinetics; Liver; Male; Metabolic Clearance Rate; Midazolam; NADP; Propranolol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Saquinavir; Water

2018