midazolam and lu 208075

midazolam has been researched along with lu 208075 in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	4 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Burhenne, J; Haefeli, WE; Hellwig, R; Hoffmann, MM; Markert, C; Mikus, G; Weiss, J	1
Burhenne, J; Haefeli, WE; Hellwig, R; Hoffmann, MM; Kalafut, P; Kastner, IM; Markert, C; Mikus, G; Schweizer, Y; Weiss, J	1

Reviews

1 review(s) available for midazolam and lu 208075

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for midazolam and lu 208075

Article	Year
Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1. European journal of clinical pharmacology, 2013, Volume: 69, Issue:10 Topics: Administration, Oral; Adult; Area Under Curve; Clarithromycin; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Administration Schedule; Drug Interactions; Female; Gene Frequency; Humans; Liver-Specific Organic Anion Transporter 1; Male; Metabolic Clearance Rate; Midazolam; Nontherapeutic Human Experimentation; Organic Anion Transporters; Phenylpropionates; Polymorphism, Genetic; Pyridazines	2013
The effect of induction of CYP3A4 by St John's wort on ambrisentan plasma pharmacokinetics in volunteers of known CYP2C19 genotype. Basic & clinical pharmacology & toxicology, 2015, Volume: 116, Issue:5 Topics: Administration, Oral; Adult; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Drug Administration Schedule; Enzyme Induction; Female; Genotype; Germany; Healthy Volunteers; Herb-Drug Interactions; Humans; Hypericum; Male; Midazolam; Pharmacogenetics; Phenotype; Phenylpropionates; Plant Extracts; Pyridazines	2015

Article

Year

Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1.

European journal of clinical pharmacology, 2013, Volume: 69, Issue:10

Topics: Administration, Oral; Adult; Area Under Curve; Clarithromycin; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Administration Schedule; Drug Interactions; Female; Gene Frequency; Humans; Liver-Specific Organic Anion Transporter 1; Male; Metabolic Clearance Rate; Midazolam; Nontherapeutic Human Experimentation; Organic Anion Transporters; Phenylpropionates; Polymorphism, Genetic; Pyridazines

2013

The effect of induction of CYP3A4 by St John's wort on ambrisentan plasma pharmacokinetics in volunteers of known CYP2C19 genotype.

Basic & clinical pharmacology & toxicology, 2015, Volume: 116, Issue:5

Topics: Administration, Oral; Adult; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Drug Administration Schedule; Enzyme Induction; Female; Genotype; Germany; Healthy Volunteers; Herb-Drug Interactions; Humans; Hypericum; Male; Midazolam; Pharmacogenetics; Phenotype; Phenylpropionates; Plant Extracts; Pyridazines

2015

Other Studies

1 other study(ies) available for midazolam and lu 208075

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010