midazolam has been researched along with flumazenil in 515 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 105 (20.39) | 18.7374 |
| 1990's | 249 (48.35) | 18.2507 |
| 2000's | 91 (17.67) | 29.6817 |
| 2010's | 53 (10.29) | 24.3611 |
| 2020's | 17 (3.30) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Danhof, M; Mandema, JW; Tukker, E | 1 |
| Bianchi, G; Stenier, P | 1 |
| Mody, I; Otis, TS | 1 |
| Dudchenko, P; Paul, B; Sarter, M | 1 |
| Chollet-Rivier, M; Ravussin, P | 1 |
| Adu-Gyamfi, Y; el-Attar, A; Tawfique, K | 1 |
| Benson, GJ; Gross, ME; Olson, WA; Thurmon, JC; Tranquilli, WJ | 1 |
| Bibbey, D; Green, JR; Haines, DJ | 1 |
| Boone, MS; Emmett-Oglesby, MW; Pugh, SL | 1 |
| Barral, N; Costes, H; Duvaldestin, P; Lebrault, C; Raimbault, E | 1 |
| Chakrabarti, MK; Galletly, DC; Wang, C; Whitwam, JG | 1 |
| Eldar, I; Lieberman, N; Nerubay, J; Perel, A; Shiber, R | 1 |
| Fennelly, ME; Galletly, DC; Powell, H; Whitwam, JG | 1 |
| Baktai, G; Kovács, L; Márialigeti, T; Székely, E | 1 |
| Ilkiw, JE | 1 |
| Askenasi, R; Leduc, D; Lheureux, P; Vranckx, M | 1 |
| Chan, L; Hui, E; Rodrigo, MR | 1 |
| Breheny, FX | 1 |
| Dierks, T; Engelhardt, W; Friess, K; Hartung, E; Sold, M | 1 |
| Ator, NA; Griffiths, RR; Sannerud, CA | 1 |
| Gent, JP; Goodchild, CS; Serrao, JM | 1 |
| Falk, JL; Lau, CE; Tang, M; Vigorito, M | 1 |
| Ball, DM; Glue, P; Nutt, DJ; Wilson, S | 1 |
| Allen, M; Cook, JM; Griffiths, RR; Sannerud, CA | 1 |
| Birch, B; Curran, HV | 1 |
| Barclay, J; Clark, M; Grainger, JK; Holden, C; Kubota, Y; Reyes-Guerra, T; Weaver, J | 1 |
| Friehs, G; Hackl, A; Juettner, FM; Ratzenhofer, B | 1 |
| Birch, BR; Chave, H; Gelister, JS; Miller, RA; Parker, CJ | 1 |
| Besson, JM; Clavier, N; Lombard, MC | 1 |
| Anson, KM; Birch, BR; Cooper, J; Kalmanovitch, DV; Miller, RA | 1 |
| Boysen, K; Crawford, ME; Krintel, JJ; Sonne, NM; Valentin, N; Wegmann, F | 1 |
| Amrein, R; Hetzel, W | 2 |
| Fischer, M; Malchow, H; Mühlhofer, H; Pilot, J; Rohde, H; Saletin, M | 1 |
| Martínez Soto, I; Martinón Sánchez, JM; Peña Guitián, J; Relova Quinteiro, JL; Rivas Pumar, P; Rodríguez Núñez, A | 1 |
| Bell, D; Geller, E; McCloy, R; Miller, R; Park, G; Pearson, R; Whitwam, J | 1 |
| Kaniaris, PK; Sarlis, NJ | 1 |
| De Aguiar, JC; Graeff, FG; Guimarães, FS; Russo, AS | 2 |
| Abay, K; Berberich, E; Duvaldestin, P; Melon, E; Nguyen, JP; Orliaguet, G | 1 |
| Conard, P; Gross, JB; Weller, RS | 1 |
| Cooper, SA; MacAfee, K; McKenna, D; Quinn, PD | 1 |
| Cold, GE; Holdgård, HO; Jensen, S; Johansen, UT; Knudsen, L | 1 |
| Kataja, J; Kaukinen, L; Kaukinen, S | 1 |
| Lenz, K; Loimer, N; Presslich, O; Schmid, R | 1 |
| Bain, O; Kremsner, PG; Laukamm-Josten, U | 1 |
| Doenicke, A; Greim, M; Juhl, G; Rampf, U; Suttmann, H | 1 |
| Hicks, TP; Oka, JI | 1 |
| McCloy, RF; Pearson, RC | 1 |
| Hole, K; Rosland, JH | 1 |
| Smilov, I; Traĭkova, V | 1 |
| Furtwängler, W; Huber, C; Luger, TJ; Morawetz, RF; Schlager, A; Schreithofer, D | 1 |
| Isaac, PA; Okell, RW; Piggott, SE; Roberts, B; Robinson, JO; Rosen, M; Sanders, LD | 1 |
| Baraka, A; Sibai, AM; Sibai, AN | 1 |
| Clapham, MC; Fisher, GC; Hutton, P | 1 |
| Artru, AA | 2 |
| Bill, KM; Clarke, RS; Fee, JP | 1 |
| Bovill, JG; Breimer, LT; Burm, AG; Danhof, M; de Voogt, JW; Hennis, PJ; Spierdijk, J; Vletter, AA | 1 |
| Carter, JA; Collins, S | 1 |
| Fassoulaki, A; Vassiliou, M | 1 |
| Andrew, LJ; Bacon-Shone, J; Gunawardene, WM; Jones, RD; Lawson, AD | 1 |
| Ackerman, BH; Olsen, KM; Pablo, CS | 1 |
| Chan, KH; Chen, CF; Hseu, SS; Lee, TY; Yu, HH | 1 |
| Ashley, N; Dundas, CR; Dunk, AA; Hudson, M; Mowat, G; Norton, AC | 1 |
| Anderson, JA; Ochs, MW; Owsley, TG; Tucker, MR | 1 |
| Ford, MJ; Stolarek, IH | 1 |
| Geller, E; Lauven, P; Thomson, D; Whitwam, J | 1 |
| Whitwam, JG | 3 |
| Bardhan, KD; McCloy, RF; Morris, P; Pearson, RC | 1 |
| Anson, K; Birch, BR; Gelister, J; Miller, RA; Parker, C | 1 |
| Marty, J; Nitenberg, A | 1 |
| Gobeaux, D; Sardnal, F | 1 |
| Camu, F; Claeys, MA; Halim, B; Schneider, I | 1 |
| Nilsson, A | 1 |
| Bell, GD; Carter, AS; Coady, T; Lee, J; Morden, A | 1 |
| Geller, E; Weinbrum, A | 1 |
| Wolff, J | 2 |
| Kulka, PJ; Lauven, PM | 1 |
| Apffelstaedt, C; Kulka, PJ; Lauven, PM; Schüttler, J | 1 |
| Kochs, E; Schulte am Esch, J | 1 |
| Bayer-Berger, M; Chiolero, R; Freeman, J; Godat, L; Ravussin, PA | 1 |
| Dundas, CR; Norton, AC | 1 |
| Pepperman, ML | 1 |
| Davies, CA; Grant, IS; Lawson, JI; Sealey, CM | 1 |
| Falk, JL; Lau, CE; Tang, M | 2 |
| Harrop-Griffiths, AW; Jewkes, DA; Watson, NA | 1 |
| Harvey, PB; Kestin, IG; Nixon, C | 1 |
| Andrews, PJ; Lamont, MC; Wright, DJ | 1 |
| Emmanouil, DE; Quock, RM | 1 |
| Anson, KM; Birch, BR; Clifford, E; Miller, RA | 1 |
| Chakalova, E; Chernev, Ch; Gergova, L; Mincheva-Saeva, M; Smilov, I; Vlaĭkova, M | 1 |
| Hauch, MA; Mallampati, SR; Philip, BK; Simpson, TH | 1 |
| Sabbe, MB; Stevens, CW; Yaksh, TL; Yanez, A | 1 |
| Edwards, M; Gent, JP; Goodchild, CS; Serrao, JM | 1 |
| Deutsch, SI; Huntzinger, JA; Mastropaolo, J; Novitzki, MR; Rosse, RB | 1 |
| Clarke, RS; McKay, AC; McKinney, MS | 1 |
| Birch, B | 1 |
| Fischer, M; Lanius, V; Mühlhofer, H; Rohde, H | 1 |
| Garamvölgyi, G; Hamar, O | 1 |
| Johnston, IG; Restall, J; Robinson, DN | 1 |
| Aceto, E; Barberini, P; D'Alonzo, M; D'Orazio, L; Pinto, G; Reali, R | 1 |
| Freys, G; Jochum, D; Otteni, JC; Ravanello, J; Schaal, JC; Steib, A | 1 |
| Breimer, LT; Burm, AG; Spierdijk, J; Vletter, AA | 1 |
| Luger, TJ; Mitterschiffthaler, G; Morawetz, RF | 1 |
| Pedemonte, M; Velluti, R | 1 |
| Jensen, S; Kirkegaard, L; Knudsen, EB; Knudsen, L; Kruse, A | 1 |
| Birch, BR; Rosenbaum, N | 1 |
| Helmers, JH; van Leeuwen, L; Zuurmond, WW | 1 |
| Fisher, GC; Hutton, P | 1 |
| Hall, RI; Hug, CC; Schwieger, IM; Szlam, F | 1 |
| Blanc, I; Kochs, E; Schulte am Esch, J; Wüst, P | 1 |
| Bursztein, S | 1 |
| Crozier, TA; Kettler, D; Langenbeck, M; Müller, J; Radke, J; Sydow, M | 1 |
| Koot, M; Van Duin, CT; Van Miert, AS | 1 |
| Bathrelou, S; Dimitriou, B; Kottis, G; Triantaphyllidis, A | 1 |
| Bodenham, A; Park, GR | 1 |
| Galletly, DC; Short, TG | 1 |
| Dawson, P; Williams, D | 1 |
| Kulka, PJ; Lauven, PM; Rommelsheim, K; Schwilden, H | 1 |
| Turek, FW; Wee, BE | 1 |
| Cherniack, NS; Deal, EC; Haxhiu, MA; van Lunteren, E | 1 |
| Beauvoir, C; du Cailar, J; Pares-Herbute, N; Peschaud, JL | 1 |
| Lim, AG | 1 |
| Chauvin, M; Costes, H; Duvaldestin, P; Guirimand, F; Lebrault, C | 1 |
| Barakat, T; Clergue, F; Fletcher, D; Laurent, P; Lechat, JP; Viars, P | 1 |
| Catoire, P; Hort-Legrand, C; Vignoli, P | 1 |
| Bougeois, B; Desmonts, JM; Farinotti, R; Servin, F | 1 |
| Beller, JP; Curzola, U; Freys, G; Jochum, D; Otteni, JC; Ravanello, J; Steib, A | 1 |
| Burns, AM; Charlton, GA; Jellicoe, J; Linter, SP | 1 |
| Ikeda, H; Robbins, J | 2 |
| Greiner, AS; Larach, DR | 1 |
| Evans, SM; Johanson, CE | 1 |
| Boyle, WA; Doze, VA; Duncan, S; Shafer, A; White, PF | 1 |
| Slangen, JL; Woudenberg, F | 1 |
| Bremer, H; Tokic, B; Tolksdorf, W | 1 |
| Cook, JM; Griffiths, RR; Sannerud, CA | 1 |
| Garamvölgyi, G; Hamar, O; Kálmán, A | 1 |
| Cooper, SJ; Estall, LB | 1 |
| Bradley, EL; Daghero, AM; Kissin, I | 1 |
| Graeff, FG; Milani, H | 1 |
| Green, S; Hodges, H | 1 |
| Klotz, U | 1 |
| Jensen, S; Kirkegaard, L; Knudsen, L | 1 |
| Hartvig, P; Nilsson, A; Persson, MP | 2 |
| Arnulf, V; Grynne, BH; Hole, A; Nilsen, OG; Raeder, JC | 1 |
| Amrein, R; Hartmann, D; Hetzel, W; Lorscheid, T | 1 |
| Dunton, AW; Leese, P; Pitman, V; Schwam, E; Siegel, J | 1 |
| Barzelai, E; Geller, E; Halpern, P; Lewis, MC; Nevo, Y; Silbiger, A; Sorkine, P | 1 |
| Amrein, R; Bonetti, EP; Gerecke, M; Hetzel, W | 1 |
| Rodgers, RJ; Waters, AJ | 1 |
| Greenblatt, DJ; Lauven, PM; Schwilden, H; Stoeckel, H | 1 |
| Garcha, HS; Rose, IC; Stolerman, IP | 2 |
| Klotz, U; Ludwig, L; Reimann, IW; Ziegler, G | 1 |
| Crul, JF; Driessen, JJ; van der Pol, F; van Egmond, J | 1 |
| DiMicco, JA | 1 |
| Moreau, JL; Pieri, L | 1 |
| Bovill, JG; Breimer, LT; Hennis, PJ; Spierdijk, J | 1 |
| Spealman, RD | 1 |
| Barrett, JE; Witkin, JM | 1 |
| Cook, J; Larscheid, P; Takada, K; Winger, GD; Woods, JH | 1 |
| Braestrup, C; Petersen, EN; Scheel-Krüger, J | 1 |
| Barber, DJ; Cooper, SJ; Gilbert, DB; Moores, WR | 1 |
| Cook, J; Larscheid, P; Takada, K; Winger, G; Woods, JH | 1 |
| Lingjaerde, O | 1 |
| Hicks, TP; Jang, EK; Oka, JI | 1 |
| Brückner, A; Chastonay, P; Forster, A; Gemperle, M; Ricou, B | 1 |
| Carl, P; Clausen, TG; Mikkelsen, BO; Wolff, J | 1 |
| Forster, A; Juge, O; Louis, M; Nahory, A | 1 |
| Alon, E; Baitella, L; Hossli, G | 1 |
| Boas, RA; Close, A; Sage, DJ | 1 |
| Forster, A; Gemperle, M; Rouiller, M | 1 |
| Rodrigo, MR; Rosenquist, JB | 1 |
| Arnulf, V; Grynne, BH; Hole, A; Raeder, JC | 1 |
| Norris, EA; Rauch, RJ; Stolerman, IP | 1 |
| Forrest, P; Galletly, DC | 1 |
| Goodchild, CS; Serrao, JM | 1 |
| Fleischer, JE; Michenfelder, JD; Milde, JH; Moyer, TP | 1 |
| Chiolero, RL; Freeman, J; Ravussin, PA | 1 |
| Lanore, JJ; Manfredi, R; Sockeel, F; Tannières, ML; Vourc'h, G | 1 |
| Davidovich, S; Geller, E; Niv, D; Urca, G | 1 |
| Kretz, FJ; Peisdersky, B | 1 |
| Anderes, JP; Chiolero, RL; de Tribolet, N; Ledermann, P; Ravussin, P | 1 |
| Fournell, A; Freye, E | 1 |
| Bodenham, A; Brownlie, G; Dixon, JS; Park, GR | 1 |
| Hooper, PA; Rosenbaum, NL | 2 |
| Ferguson, AH; Juhl, O; Klausen, NO; Neumann, PB; Sørensen, J | 1 |
| Clapham, GJ; Merry, AF; Walker, JS | 1 |
| Hole, A; Nilsen, OG; Raeder, JC | 1 |
| Bläss, JJ; Kunz, G | 1 |
| Hennis, PJ; Mulder, AJ; Spierdijk, J; van Haastert, FA | 1 |
| Fragen, RJ; Greenblatt, DJ; Reves, JG; Vinik, HR | 1 |
| Audi, EA; Graeff, FG | 1 |
| Falk, JL; Soroka, S; Tang, M | 1 |
| Bichard, AR; Little, HJ | 1 |
| Curtis, DR; Leah, JD; Malik, R | 1 |
| Al-Khudhairi, D; Anderson, DJ; Gordon, G; Grundy, EM; Whitwam, JG | 1 |
| Collins, GI; Gath, I; Hadad, H; Weidenfeld, J | 1 |
| Falk, JL; Tang, M | 1 |
| Cooper, SJ | 1 |
| Haji, A; Ito, Y; Masuda, A; Shakunaga, K; Shibuya, N; Wakasugi, M | 1 |
| Kai, T; Kanaide, H; Kobayashi, S; Nishimura, J; Takahashi, S; Yoshimura, H | 1 |
| Desmonts, JM; Dureuil, B; Molliex, S; Montravers, P | 1 |
| Browne, J; Donnelly, M; Fitzpatrick, G | 1 |
| Mora, CT; Torjman, M; White, PF | 2 |
| Egan, TD; Egan, TE; Fiset, P; Lemmens, HL; Shafer, SL; Stanski, DR | 1 |
| Acri, JB; Witkin, JM; Wong, G | 1 |
| Bauer, TM; Ha, HR; Haberthür, C; Haefeli, WE; Hunkeler, W; Ritz, R; Scollo-Lavizzari, G; Sleight, AJ | 1 |
| Adachi, M; Akatsu, M; Okuaki, A; Sinoda, M; Tase, C; Terashima, M; Watanabe, K | 1 |
| Janvier, G; Malavialle, P | 1 |
| Clergue, F | 1 |
| Bruder, N | 1 |
| Dierks, T; Engelhardt, W; Maurer, K | 1 |
| Lee, AM; McGregor, IS; Westbrook, RF | 1 |
| Miczek, KA; Vivian, JA; Weerts, EM | 1 |
| Hayashi, T; Hill, HF; Lorenz, IH; Luger, TJ | 1 |
| Hardinge, FM | 1 |
| Pesold, C; Treit, D | 3 |
| Hansen, PA; Jensen, AG; Lybecker, H; Møller, JT | 1 |
| Alvarez, FJ; Del Rio, MC; Gomez, JI; Tamayo, E | 1 |
| Bonfiglio, MF; Fisher, LE; Geers, SM; Perch, S | 1 |
| Hanaoka, K; Ide, Y; Nagase, M; Sekiyama, H; Sumida, T; Tagami, M | 1 |
| Ator, NA; Sannerud, CA | 1 |
| Birch, BR; Miller, RA | 1 |
| Claffey, L; Dean, DM; Morris, J; Plourde, G; Trahan, M | 1 |
| Furukawa, Y; Hakoda, T; Hirashima, J; Marumo, S; Nishimura, K; Okawa, M; Tatsumi, K; Uchiyama, M; Yamamoto, T; Yoshino, A | 1 |
| Guldner, J; Holsboer, F; Lauer, CJ; Meschenmoser, C; Pollmächer, T; Steiger, A | 1 |
| Harris, JA; Westbrook, RF | 1 |
| Harris, JA; McGregor, IS; Westbrook, RF | 1 |
| Danish, M; Ross, C | 1 |
| Hayashi, K; Kim, H; Matsunaga, S; Nishimura, R; Sasaki, N; Takeuchi, A; Tamura, H | 1 |
| Jeske, AH; Redden, RJ | 1 |
| Bailine, SH; Bernstein, S; Safferman, A; Vital-Herne, J | 1 |
| Mok, MS; Pregler, JL; Steen, SN | 1 |
| Choi, H; Kano, T; Ohsumi, H; Sakamoto, M; Shibata, Y; Yasumoto, M | 1 |
| Crews, T; Erb, RJ; Leese, PT; Massarella, JW; Melia, AT; Oldfield, N; Patel, IH; Schmitt-Muskus, J; Teller, SB; Zhi, J | 1 |
| Kanayama, T; Kobayashi, M; Koshikawa, N; Murai, T; Takada, K; Tomiyama, K | 1 |
| Borisov, B; Georgiev, S; Iankov, A; Smilov, I | 1 |
| Hamada, T; Ito, Y; Joumura, K; Masuda, A; Shakunaga, K; Wakasugi, M | 1 |
| D'Honneur, G; Duvaldestin, P; el Sayed, A; Lambert, Y; Rimaniol, JM | 1 |
| Garcia de Frias, E; Lopez de Sa, E; Lopez-Herce, J | 1 |
| Ghouri, AF; Ruiz, MA; White, PF | 1 |
| Gin, T; Oh, TE; Short, TG; Tam, YH; Tan, P; Young, KK | 1 |
| McLachlan, RS; Sharpe, MD; Sprenger, H | 1 |
| Hargreaves, J; Pollard, BJ; Roberts, SP | 1 |
| Erskine, R; Langton, JA; Murphy, PJ | 1 |
| Steinhoff, BJ; Stodieck, SR | 1 |
| Hunter, KM; Luyk, NH; Parkinson, R; Zacharias, M | 1 |
| Negus, BH; Street, NE | 1 |
| Furuya, H; Kumano, H; Kuro, M; Okuda, T; Sakaki, T; Shimomura, T; Yomosa, H | 1 |
| Crettenand, G; Forster, A; Klopfenstein, CE; Morel, DR | 1 |
| Ginsberg, B; Glass, PS; Jhaveri, RM; Ossey, K | 1 |
| Chan, K; Jones, RD | 1 |
| Balbachan, O; Broderson, C; Etchepare, S; Segal, E | 1 |
| Flögel, CM; Ritter, JW; Wada, DR; Ward, DS | 1 |
| Alastra, AJ; Cohen, C; Goldberg, SR; Marley, RJ; Sannerud, CA; Serdikoff, SL | 1 |
| Block, RI; el-Zahaby, HM; Ghoneim, MM; Hinrichs, JV; Ping, ST | 1 |
| Finder, RL; Moore, PA | 1 |
| Dorrington, KL; Nagyova, B; Robbins, PA | 1 |
| Andersen, JV; Dalgaard, L; Foged, C; Friberg, L; Holm, S; Lassen, NA; Videbaek, C; Wammen, S | 1 |
| Gallagher, LV; Greene, SA; Keegan, RD; Moore, MP | 1 |
| Crawford, ME; Jensen, FM; Madsen, JB; Toftdahl, DB | 1 |
| Fan, YP; Lee, TS; Wu, Y | 1 |
| Lawrence, K | 1 |
| Biggio, G; Dazzi, L; Gessa, GL; Imperato, A; Obinu, MC | 1 |
| Agarwal, RK; Court, MH; Dodman, NH; Greenblatt, DJ; Kumar, MS | 1 |
| Kanayama, T; Koshikawa, N; Murai, T; Takada, K | 1 |
| Blouin, RT; Conard, PF; Gross, JB; Perreault, S | 1 |
| Brown, AG; Chan, K; Jones, RD; Mya, GH; Roulson, CJ; Smith, ID | 1 |
| Coulthard, P; Mitchell, K; Snowdon, AT; Thomson, PJ | 1 |
| Graybeal, JM; Russell, GB; Vance, WT | 1 |
| Acri, JB; Barrett, JE; Gleeson, S; Witkin, JM; Wong, G | 1 |
| Blanc, P; Carbajal, R; Lenclen, R; Oliver-Martin, M; Paupe, A; Simon, N | 1 |
| Galletly, DC; Robinson, BJ; Williams, TB | 1 |
| Foshee, SL; Thurston, TA; Williams, CG | 1 |
| Fiset, P; Gregg, KM; Minto, CF; Schnider, TW; Shafer, SL | 1 |
| Meier-Abt, PJ; Radovanovic, D; Wyss, PA | 1 |
| Day, TK; Roge, CK | 1 |
| Gallagher, TM; Thakker, P | 1 |
| Johnston, RE | 1 |
| Cooper, SJ; Higgs, S | 3 |
| Blouin, RT; Conard, PF; Gross, JB; Häussler, J; Zandsberg, S | 1 |
| al-Kawas, FH; Benjamin, SB; Fleischer, DE; Gallagher, J; Ginsberg, G; Kankaria, A; Lewis, JH; Nguyen, CC | 1 |
| Feng, J; Kendig, JJ | 1 |
| Acri, JB; Barrett, JE; Gleeson, S; Witkin, JM | 1 |
| File, SE; Gonzalez, LE | 1 |
| Bloomfield, PM; Cunningham, VJ; Gunn, RN; Malizia, AL; Nutt, DJ; Waters, SH; Wilson, SJ | 1 |
| Mariathasan, EA; Stolerman, IP; White, JA | 1 |
| Eklund, A; Gupta, A; Lennmarken, C; Lind, S | 1 |
| Lush, RJ; Mainwaring, CJ; Singer, CR; Smith, JG; Wong, C | 1 |
| Koht, A; Moss, JI | 1 |
| Dohi, S; Furuya, K; Ishizawa, Y; Yamagishi, S | 1 |
| Rushatamukayanunt, W; Tritrakarn, T | 1 |
| Furuya, A; Imamura, M; Kashimoto, S; Kumazawa, T; Nonaka, A | 1 |
| Kanaya, N; Nakae, Y; Namiki, A | 1 |
| Cuparencu, B; Horák, A; Horák, J; Lenghel, A | 1 |
| Todd, KH | 1 |
| Chudnofsky, CR | 1 |
| Hashimoto, Y; Hirota, K; Ishihara, H; Kudo, T; Matsuki, A; Ohtomo, N | 1 |
| Albers, G; Burkhart, K; Hoffman, J; Kelley, M; Liebelt, E; Massarella, J; McCubbin, MM; Shannon, M | 1 |
| Cordell, WH; Heniff, MS; Moore, GP; Nelson, DR; Trout, A | 1 |
| Massanari, M; Novitsky, J; Reinstein, LJ | 1 |
| Rodrigo, MR | 1 |
| Gevers, AM; Hendrickx, A; Macken, E; Rutgeerts, P | 1 |
| Chen, P; Coldwell, SE; Kaufman, E; Kharasch, ED; Mautz, D; Milgrom, P; Ramsay, DS | 1 |
| Kunimatu, T; Kyoda, N; Misaki, T; Oka, S; Tajima, A; Takada, K | 1 |
| Griffiths, RR; Kaminski, BJ; Weerts, EM | 1 |
| Satumae, T; Taguchi, N; Takeshima, R; Watanabe, S | 1 |
| Hesselbjerg, L; Koscielniak-Nielsen, ZJ; Stens-Pedersen, HL | 1 |
| Brandt, MR; France, CP; Gerak, LR | 1 |
| Cutilli, BJ; Saunders, W; Smith, BM | 1 |
| Davis, DP; Hamilton, RS; Webster, TH | 1 |
| Chassard, D | 1 |
| Murata, Y | 1 |
| DeBoer, P; Moor, E; Westerink, BH | 1 |
| File, SE; Gonzalez, LE; Ouagazzal, AM | 1 |
| Honma, Y; Matsuzaki, T; Namiki, A; Tsujiguchi, N; Yamakage, M | 1 |
| Sato, I; Takano, M; Takano, Y | 1 |
| Larson, JS; Lunn, JJ | 1 |
| Aran, G; Guven, H; Kalkan, S; Ozturk, T; Tuncok, Y | 1 |
| Chang, AC; Chen, YK; Solinger, MA; Yang, DT | 1 |
| Langewitz, W; Müller, BU; Ritz, R; Schächinger, H; Strobel, W | 1 |
| Duarte, ID; Francischi, JN; Salgado, JV; Tatsuo, MA; Yokoro, CM | 1 |
| Bergman, J; Paronis, CA | 1 |
| Combes, X; Dhonneur, G; Duvaldestin, P; Leroux, B | 1 |
| Fryzel, S; Gerbasi, F; Hourrigan, J; Masserant, J; Motz, J; Nagelhout, J; Wakefield, F; Wigton, T; Zaglaniczny, KL | 1 |
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| Masaki, Y; Oshima, T; Toyooka, H | 1 |
| Lelas, S; Rowlett, JK; Spealman, RD | 1 |
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| Bowery, N; Castro, AR; Castro-Lopes, JM | 1 |
| Barnett, JL; Chaffee, BW; Elta, GH; Ryan, ML; Walter, V; Wille, RT | 1 |
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| France, CP; Gerak, LR; Lelas, S | 2 |
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| France, CP; Gerak, LR; McMahon, LR | 1 |
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| Carter, L; Cook, JM; France, CP; Gerak, LR; Ma, C; McMahon, LR | 1 |
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| Bailey, PL; Basco, MG; Hayes, JL; Litman, RS; Schwartz, AR; Ward, DS | 1 |
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| France, CP; McMahon, LR | 2 |
| Bertino, JS; Jones, CL; Morrison, AL; Nafziger, AN; Rocci, ML; Rogers, JF | 1 |
| Andjelković, DS; Bokonjić, DR; Obradović, DI; Savić, MM; Ugresić, ND | 1 |
| Coop, A; France, CP; McMahon, LR; Winger, G; Woolverton, WL | 1 |
| Belhassen, B; Glick, A; Weinbroum, AA | 1 |
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| Hong, Z; Lu, SY; Wang, DS; Zhu, HL | 1 |
| Rieger, HJ | 1 |
| Bragulat, E; Coll-Vinent, B; Espinosa, G; Fernández, C; Millá, J; Miró, O; Sala, X; Sánchez, M | 1 |
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| Engler, J; Fairbrother, KJ; Girdler, NM; Hargaden, N; Lyne, JP; Neave, N; Rotherham, NA; Scholey, A; Wesnes, KA | 1 |
| Dehne, MG; Engel, J; Fuchs, M; Gonter, J; Hempelmann, G; Krüll, M; Matejec, R; Menges, T; Mühling, J; Nickolaus, KA; Sablotzki, A; Welters, ID; Wolff, M | 1 |
| Alarcón Fernández, O; Avilés Ruiz, J; Baudet Arteaga, JS; Borja Gutiérrez, E; Borque Barrera, P; Martín Martín, JM; Moreno Sanfiel, M; Sánchez del Río, A | 1 |
| Bokonjić, DR; Cook, JM; Obradović, DI; Sarma, PV; Savić, MM; Ugresić, ND | 1 |
| Forman, SA; Rüsch, D | 1 |
| Brooks, DJ; Cunningham, VJ; Feeney, A; Lingford-Hughes, AR; Nutt, DJ; Stevenson, B; Wilson, SJ | 1 |
| Araki, H; Fujiwara, Y; Shimada, Y | 1 |
| Baburin, I; Hering, S; Hohaus, A; Khom, S; Sieghart, W; Timin, EN | 1 |
| Shin, JE; Yi, SY | 1 |
| Eskandari, MH; Vesal, N | 1 |
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| Cruź, CM; France, CP; Koek, W; McMahon, LR; Weltman, RH | 1 |
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| France, CP; Javors, MA; McMahon, LR | 1 |
| Collier, CB | 1 |
| Antonicoli, S; Bianconi, L; Frongillo, D; Mennuni, M; Molle, G; Rossi, P; Toscano, S; Venturini, E | 1 |
| Capasso, A; Cavallo, F; Raffa, RB | 1 |
| Hecht, M; Kaps, M; Rosengarten, B | 1 |
| Danhof, M; Gunput, RA; Liefaard, LC; Voskuyl, RA | 1 |
| Hikasa, Y; Ueoka, N | 2 |
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| Bracken, S; Ceremuga, TE; Cline, M; Flores, J; McCall, S; Taylor, JE | 1 |
| Hashimoto, A; Ito, K; Jin, XL; Kobayashi, H; Maeda, M; Matsuda, M; Suzuki, T; Takahashi, S; Tamaki, R; Yoshikawa, M | 1 |
| Anseloni, VC; Gold, MS | 1 |
| Canto-de-Souza, A; dos Reis, LM | 1 |
| Adachi, Y; Doi, M; Obata, Y; Sato, S; Suzuki, K | 1 |
| Higuchi, H; Maeda, S; Miyawaki, T; Shimada, M | 1 |
| Béchir, M; Keel, M; Meierhans, R; Stocker, R; Stover, JF | 1 |
| Bertino, JS; Fullerton, T; Lawendy, NM; Ma, JD; Nafziger, AN; Snyder, PJ | 1 |
| Ceremuga, TE; Duncan, R; Jones, P; McCall, S; Moe, N; Raines, T | 1 |
| Barbalho, CA; Canto-de-Souza, A; Nunes-de-Souza, RL | 1 |
| Douglas, SA; Furukawa, K; Hashiba, E; Hirota, K; Kawaguchi, Y; Kudo, M; Kudo, T; Kushikata, T; Ono, T; Yoshida, H | 1 |
| Hayes, CM; Heller, M; Krejci, NC | 1 |
| Darbra, S; Pallarès, M | 1 |
| Creighton, P; Heard, C; Lerman, J | 1 |
| Grant, KA; Helms, CM; Rogers, LS | 1 |
| Chang, YT; Hsing, CH; Huang, BM; Leu, SF; Poon, PW; So, EC | 1 |
| de Freitas, O; Kawano, DF; Pereira, LR; Sankarankutty, AK; Ueta, J | 1 |
| Facco, E; Favero, L; Manani, G; Zanette, G | 1 |
| Cordovil, A; Cury, AF; Fischer, CH; Guimarães, LA; Lira Filho, EB; Monaco, C; Morhy, SS; Naccarato, GA; Rodrigues, AC; Tavares, G; Vieira, ML | 1 |
| Shelton, KL | 1 |
| Gerónimo Pardo, M; Mateo Cerdán, CM; Moreno Salcedo, JM | 1 |
| Kanmura, Y; Moriyama, T; Tsuneyoshi, I | 1 |
| Oppitz, F | 1 |
| McKenzie, WS; Rosenberg, M | 1 |
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| Dickinson, C; Henthorn, KM | 1 |
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| France, CP; Gerak, LR | 3 |
| Ceremuga, TE; Godwin, S; Hitchcock, G; Johnson, M; Jones, W; Leiter, E; McCall, S; Sedgwick, W | 1 |
| Girdler, NM; McCabe, JF; Thorpe, RJ; Wilson, KE | 1 |
| Arroyo-Cózar, M; Gabaldón Conejos, T; Grau Delgado, J | 1 |
| Ceremuga, TE; Franz, M; Haese, C; Henkes, H; Johnson, AD; Kendall, O; LeDoux, J; Legaspi, A; McCall, S; Monroe, J; Williams, D | 1 |
| Huang, MY; Ichinohe, T; Kaneko, Y; Matsuura, N | 1 |
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| Guzman, DS; Lahner, LL; Mans, C; Paul-Murphy, J; Sladky, KK | 1 |
| Aoki, K; Gokan, D; Hirose, N; Iwasaki, K; Kato, J; Ogawa, S; Ogawa, Y; Ueda, K | 1 |
| France, CP; Gerak, LR; Yoon, SS; Zanettini, C | 1 |
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| France, CP; Gerak, LR; Zanettini, C | 1 |
| de Jong, L; Kos-Foekema, HA; Mathus-Vliegen, EM | 1 |
| Ahn, JH; Kang, KJ; Kim, JJ; Kim, S; Lee, JH; Min, BH; Rhee, PL; Tae, CH | 1 |
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| Dewitte, A; Fleureau, C; Germain, A; Joannes-Boyau, O; Ouattara, A; Perrier, V; Rozé, H | 1 |
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| Aoki, K; Iwasaki, K; Kato, J; Ogawa, S; Ogawa, Y; Ueda, K; Yanagida, R | 1 |
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| Bailey, H; Ceremuga, TE; Criss, J; Fried, J; Johnson, AD; Kenner, C; Lathrop, K; Linton, J; Lucia, A; Padron, G; Stailey, O; Taylor, A; Valdivieso, D | 1 |
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33 review(s) available for midazolam and flumazenil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
A clinical double-blind study of flumazenil, antagonist of benzodiazepines, in loco-regional anesthesia.
Topics: Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Preanesthetic Medication; Receptors, GABA-A | 1992 |
Other potentially useful new injectable anesthetic agents.
Topics: Anesthesia; Anesthetics; Animals; Cats; Dogs; Flumazenil; Midazolam; Propofol | 1992 |
Pharmacology of drugs frequently used in ICUs: midazolam and flumazenil.
Topics: Critical Care; Flumazenil; Humans; Intensive Care Units; Midazolam | 1991 |
[Dormicum, aneksat and their use in obstetrical and gynecological operations].
Topics: Anesthesia, Obstetrical; Animals; Anti-Anxiety Agents; Female; Flumazenil; Genital Diseases, Female; Humans; Midazolam; Obstetric Labor Complications; Pregnancy; Pregnancy Complications | 1990 |
The use of midazolam and flumazenil in diagnostic and short surgical procedures.
Topics: Ambulatory Surgical Procedures; Anesthesia, Conduction; Dentistry; Endoscopy; Flumazenil; Humans; Midazolam | 1990 |
The use of midazolam and flumazenil in locoregional anaesthesia: an overview.
Topics: Anesthesia, Conduction; Anesthesia, Local; Flumazenil; Hemodynamics; Humans; Midazolam; Respiration | 1990 |
Autonomic and hormonal responses after the use of midazolam and flumazenil.
Topics: Animals; Catecholamines; Flumazenil; Hormones; Humans; Midazolam; Stress, Physiological; Stress, Psychological | 1990 |
Pharmacology of Dormicum (midazolam) and Anexate (flumazenil).
Topics: Animals; Chemical Phenomena; Chemistry; Flumazenil; Humans; Infusions, Intravenous; Mice; Midazolam; Rats | 1990 |
Resedation.
Topics: Anesthesia Recovery Period; Benzodiazepines; Flumazenil; Half-Life; Humans; Infusions, Intravenous; Midazolam; Postoperative Period | 1990 |
Cerebrovascular and metabolic effects of midazolam and flumazenil.
Topics: Anesthesia, Intravenous; Cerebrovascular Circulation; Flumazenil; Hemodynamics; Humans; Midazolam; Oxygen | 1990 |
Anaesthesia techniques for midazolam and flumazenil--an overview.
Topics: Anesthesia, Intravenous; Flumazenil; Half-Life; Humans; Infusions, Intravenous; Midazolam; Postoperative Period | 1990 |
Midazolam and flumazenil in neuroanaesthesia.
Topics: Anesthesia, Intravenous; Animals; Cerebrovascular Circulation; Evoked Potentials; Flumazenil; Hemodynamics; Humans; Intracranial Pressure; Midazolam | 1990 |
Behavioural pharmacology of food, water and salt intake in relation to drug actions at benzodiazepine receptors.
Topics: Animals; Anti-Anxiety Agents; Appetite; Appetite Depressants; Benzodiazepines; Benzodiazepinones; Carbolines; Chlordiazepoxide; Chlorides; Choice Behavior; Diazepam; Drinking Behavior; Feeding Behavior; Flumazenil; Food Deprivation; Food Preferences; gamma-Aminobutyric Acid; Ion Channels; Midazolam; Picrotoxin; Punishment; Pyrazoles; Receptors, GABA-A; Satiation; Sodium Chloride; Species Specificity | 1985 |
Flumazenil for post-operative recovery after general anaesthesia.
Topics: Anesthesia, General; Double-Blind Method; Flumazenil; Flunitrazepam; Humans; Midazolam; Postoperative Care; Random Allocation; Receptors, GABA-A | 1988 |
Clinical pharmacology of flumazenil.
Topics: Animals; Flumazenil; Flunitrazepam; Humans; Mathematics; Midazolam; Receptors, GABA-A; Sleep | 1988 |
Clinical pharmacology of dormicum (midazolam) and anexate (flumazenil).
Topics: Animals; Biotransformation; Flumazenil; Humans; Midazolam | 1988 |
Benzodiazepines and their antagonists: a pharmacoethological analysis with particular reference to effects on "aggression".
Topics: Aggression; Agonistic Behavior; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Conflict, Psychological; Environment; Flumazenil; Humans; Midazolam; Predatory Behavior; Pyrazoles; Social Behavior; Species Specificity; Time Factors | 1985 |
Midazolam--is antagonism justified?
Topics: Adult; Aged; Cardiovascular Diseases; Flumazenil; Humans; Midazolam; Respiratory Insufficiency | 1988 |
Midazolam: pharmacology and uses.
Topics: Adult; Aged; Aging; Ambulatory Surgical Procedures; Anesthetics; Animals; Benzodiazepines; Benzodiazepinones; Biotransformation; Brain; Chemical Phenomena; Chemistry; Female; Flumazenil; Hemodynamics; Humans; Hypnotics and Sedatives; Hypoxia, Brain; Injections, Intravenous; Kinetics; Male; Midazolam; Middle Aged; Nausea; Preanesthetic Medication; Respiration; Sex Factors; Thrombophlebitis | 1985 |
Narcotic/sedative receptor antagonists.
Topics: Anesthesia, Dental; Anti-Anxiety Agents; Binding, Competitive; Conscious Sedation; Drug Interactions; Emergencies; Flumazenil; Humans; Midazolam; Naloxone; Narcotic Antagonists; Receptors, GABA-A; Receptors, Opioid | 1993 |
Benzodiazepines for intravenous conscious sedation: agonists and antagonists.
Topics: Anesthesia, Dental; Benzodiazepines; Conscious Sedation; Diazepam; Flumazenil; Humans; Injections, Intravenous; Lorazepam; Midazolam | 1993 |
Flumazenil and midazolam in anaesthesia.
Topics: Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Benzodiazepines; Drug Synergism; Endoscopy; Flumazenil; GABA Modulators; Hemodynamics; Humans; Hypnotics and Sedatives; Midazolam | 1995 |
Reversal of midazolam-induced laryngospasm with flumazenil.
Topics: Anti-Anxiety Agents; Antidotes; Conscious Sedation; Electric Countershock; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Laryngismus; Male; Midazolam; Middle Aged; Recurrence; Respiratory Insufficiency; Retreatment | 1998 |
Comparing drugs for short-term sedation.
Topics: Anesthesia; Benzodiazepines; Conscious Sedation; Diazepam; Flumazenil; Humans; Lorazepam; Midazolam; Pain; Propofol | 1994 |
Completion of upper endoscopic procedures despite paradoxical reaction to midazolam: a role for flumazenil?
Topics: Adult; Akathisia, Drug-Induced; Antidotes; Conscious Sedation; Endoscopy, Digestive System; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged | 2000 |
The midazolam-induced paradox phenomenon is reversible by flumazenil. Epidemiology, patient characteristics and review of the literature.
Topics: Aged; Aggression; Anesthesia, Epidural; Anesthesia, Spinal; Anti-Anxiety Agents; Female; Flumazenil; Humans; Hypnotics and Sedatives; Intraoperative Complications; Male; Midazolam; Middle Aged; Postoperative Complications; Psychomotor Agitation; Risk Factors | 2001 |
[Parenteral use of benzodiazepines in dentistry in order to reduce stress in adult patients].
Topics: Adult; Anesthetics; Antidotes; Conscious Sedation; Dental Care; Diazepam; Flumazenil; Humans; Midazolam; Middle Aged; Monitoring, Physiologic; Oximetry; Premedication; Stress, Psychological | 1996 |
Paradoxical reactions to benzodiazepines in intravenous sedation: a report of 2 cases and review of the literature.
Topics: Adult; Anesthesia, Dental; Anti-Anxiety Agents; Antidotes; Conscious Sedation; Dental Anxiety; Female; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Injections, Intravenous; Midazolam; Tooth Extraction | 2002 |
Delayed postoperative agitation in a child after preoperative midazolam.
Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Algorithms; Ambulatory Surgical Procedures; Antidotes; Causality; Child, Preschool; Decision Trees; Drug Monitoring; Emergency Treatment; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Ear Ventilation; Nurse's Role; Nursing Assessment; Parents; Postanesthesia Nursing; Preanesthetic Medication | 2007 |
Midazolam and other benzodiazepines.
Topics: Anesthetics, Intravenous; Animals; Benzodiazepines; Biotransformation; Central Nervous System; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Humans; Lorazepam; Midazolam; Molecular Structure; Receptors, GABA-A; Structure-Activity Relationship | 2008 |
Review of Intranasally Administered Medications for Use in the Emergency Department.
Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics | 2017 |
A Review of the use of Flumazenil for the Reversal of Midazolam Conscious Sedation in Dentistry.
Topics: Anesthesia, Dental; Conscious Sedation; Flumazenil; Humans; Hypnotics and Sedatives; Midazolam | 2017 |
149 trial(s) available for midazolam and flumazenil
| Article | Year |
|---|---|
A clinical double-blind study of flumazenil, antagonist of benzodiazepines, in loco-regional anesthesia.
Topics: Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Preanesthetic Medication; Receptors, GABA-A | 1992 |
Midazolam-flumazenil vs. propofol in ambulatory ENT endoscopic procedures.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthesia Recovery Period; Anesthesia, Intravenous; Awareness; Blood Pressure; Cardiovascular Diseases; Endoscopy; Flumazenil; Heart Rate; Humans; Midazolam; Middle Aged; Otorhinolaryngologic Diseases; Propofol; Risk Factors; Safety; Time Factors | 1992 |
Flumazenil reversal of midazolam sedation for dental procedures.
Topics: Adult; Ambulatory Care; Dentistry, Operative; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam | 1992 |
The effects of flumazenil on alertness and hypoxia in elderly patients after ERCP.
Topics: Aged; Aged, 80 and over; Cholangiopancreatography, Endoscopic Retrograde; Double-Blind Method; Female; Flumazenil; Humans; Hypoxia; Male; Midazolam; Middle Aged; Oxygen; Postoperative Complications; Prospective Studies; Wakefulness | 1992 |
Oxygen consumption after flumazenil reversal.
Topics: Adult; Double-Blind Method; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Oxygen Consumption; Surgical Procedures, Operative | 1992 |
Use of flumazenil for intraoperative arousal during spine fusion.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Arousal; Female; Flumazenil; Humans; Intraoperative Period; Male; Midazolam; Spinal Fusion | 1992 |
Midazolam sedation reversed with flumazenil for cardioversion.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Arrhythmias, Cardiac; Blood Pressure; Double-Blind Method; Electric Countershock; Flumazenil; Heart Rate; Humans; Midazolam; Middle Aged | 1992 |
Use of midazolam ('Dormicum') and flumazenil ('Anexate') in paediatric bronchology.
Topics: Anesthesia; Atropine; Bronchoscopy; Child, Preschool; Chronic Disease; Drug Administration Schedule; Electrocardiography; Feasibility Studies; Female; Fentanyl; Flumazenil; Humans; Infant; Lung Diseases; Male; Midazolam; Nitrous Oxide; Oxygen; Premedication; Pulse; Succinylcholine | 1992 |
Flumazenil reversal of conscious sedation for minor oral surgery.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Conscious Sedation; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Molar, Third; Patient Discharge; Placebos; Sleep Stages; Tooth Extraction; Tooth, Impacted | 1992 |
Reversal of midazolam sedation with flumazenil.
Topics: Double-Blind Method; Drug Evaluation; Female; Flumazenil; Humans; Infusions, Intravenous; Male; Midazolam; Respiration, Artificial; Time Factors | 1992 |
Differentiating the sedative, psychomotor and amnesic effects of benzodiazepines: a study with midazolam and the benzodiazepine antagonist, flumazenil.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Cognition; Double-Blind Method; Emotions; Female; Flicker Fusion; Flumazenil; Humans; Hypnotics and Sedatives; Male; Memory; Midazolam; Psychomotor Performance; Reaction Time | 1991 |
Sedation for day-case urology: an assessment of patient recovery profiles after midazolam and flumazenil.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Conscious Sedation; Cystoscopy; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Psychomotor Performance; Urology | 1991 |
Recovery after total intravenous anaesthesia using combined midazolam/alfentanil infusion and reversal with flumazenil.
Topics: Acoustic Stimulation; Adult; Alfentanil; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Blood Pressure; Female; Flumazenil; Glasgow Coma Scale; Heart Rate; Humans; Infusions, Intravenous; Male; Midazolam; Middle Aged; Nitrous Oxide; Patient Satisfaction; Reaction Time; Respiration | 1991 |
A randomised controlled trial to evaluate the effects of flumazenil after midazolam premedication in outpatients undergoing colonoscopy.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Colonoscopy; Conscious Sedation; Flumazenil; Humans; Injections, Intravenous; Midazolam; Middle Aged | 1991 |
Flumazenil antagonism of midazolam-induced ventilatory depression.
Topics: Adult; Blood Pressure; Double-Blind Method; Flumazenil; Heart Rate; Humans; Injections, Intravenous; Male; Midazolam; Monitoring, Physiologic; Respiration; Respiratory Function Tests; Respiratory Insufficiency | 1991 |
Effects of flumazenil on cerebral blood flow and oxygen consumption after midazolam anaesthesia for craniotomy.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Intravenous; Brain Neoplasms; Cerebrovascular Circulation; Craniotomy; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Oxygen Consumption | 1991 |
Antagonism of benzodiazepine-fentanyl anaesthesia with flumazenil.
Topics: Adult; Anesthesia, Inhalation; Anti-Anxiety Agents; Double-Blind Method; Female; Fentanyl; Flumazenil; Flunitrazepam; Humans; Male; Midazolam; Middle Aged; Preanesthetic Medication; Randomized Controlled Trials as Topic | 1990 |
[Beta activation following the intravenous administration of benzodiazepines and the specific antagonist flumazenil (Ro 15-1788)].
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Beta Rhythm; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Flumazenil; Flunitrazepam; Humans; Injections, Intravenous; Lorazepam; Male; Midazolam; Prospective Studies; Randomized Controlled Trials as Topic; Stimulation, Chemical | 1990 |
[Impairment of the cognitive faculties and the reaction capability caused by midazolam despite reversal using flumazenil].
Topics: Adult; Cognition; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Reaction Time | 1991 |
Reversal of benzodiazepine sedation with the antagonist flumazenil.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Anesthesia, Intravenous; Benzodiazepines; Cognition; Diazepam; Double-Blind Method; Female; Flumazenil; Gastroscopy; Headache; Humans; Male; Memory; Midazolam; Middle Aged; Psychomotor Performance | 1991 |
Comparison of flumazenil with aminophylline to antagonize midazolam in elderly patients.
Topics: Aged; Aged, 80 and over; Aminophylline; Anesthesia, Spinal; Double-Blind Method; Flumazenil; Humans; Male; Midazolam; Middle Aged; Prostate; Time Factors | 1991 |
Psychomotor and clinical assessment of flumazenil as an antagonist of midazolam.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Double-Blind Method; Doxapram; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Psychomotor Performance; Random Allocation | 1991 |
Pharmacokinetic-pharmacodynamic modelling of the interaction between flumazenil and midazolam in volunteers by aperiodic EEG analysis.
Topics: Adult; Drug Interactions; Electroencephalography; Flumazenil; Humans; Male; Midazolam | 1991 |
Antagonism of the hypnotic effect of midazolam in children: a randomized, double-blind study of placebo and flumazenil administered after midazolam-induced anaesthesia.
Topics: Anesthesia Recovery Period; Anesthesia, General; Child; Child, Preschool; Circumcision, Male; Double-Blind Method; Flumazenil; Humans; Male; Midazolam; Phimosis; Placebos; Psychomotor Performance | 1991 |
Postoperative analgesic requirements following flumazenil administration.
Topics: Adult; Analgesics; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Morphine; Pain, Postoperative; Prospective Studies; Therapeutic Equivalency; Time Factors | 1990 |
Flumazenil as an antagonist for midazolam anesthesia in outpatient surgery.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Female; Flumazenil; Humans; Midazolam; Middle Aged | 1990 |
The value of flumazenil in the reversal of midazolam-induced sedation for upper gastrointestinal endoscopy.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Endoscopy, Gastrointestinal; Female; Flicker Fusion; Flumazenil; Humans; Male; Midazolam; Middle Aged; Premedication | 1990 |
The effectiveness of flumazenil in reversing the sedation and amnesia produced by intravenous midazolam.
Topics: Amnesia; Anesthesia, Dental; Anesthesia, General; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Motor Skills; Postoperative Period; Randomized Controlled Trials as Topic; Tooth Extraction | 1990 |
Midazolam and flumazenil in gastroenterology.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Flumazenil; Gastroscopy; Humans; Male; Memory; Midazolam; Middle Aged; Psychomotor Performance; Randomized Controlled Trials as Topic | 1990 |
The role of midazolam and flumazenil in urology.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Cystoscopy; Double-Blind Method; Female; Flumazenil; Humans; Male; Memory; Midazolam; Middle Aged; Pain Measurement; Pilot Projects; Psychomotor Performance; Randomized Controlled Trials as Topic | 1990 |
Midazolam and flumazenil in ophthalmology.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Cornea; Double-Blind Method; Female; Flumazenil; Humans; Intraocular Pressure; Male; Memory; Midazolam; Randomized Controlled Trials as Topic | 1990 |
The respiratory effects of reversing midazolam sedation with flumazenil in the presence or absence of narcotics.
Topics: Anesthesia, Epidural; Blood Pressure; Female; Flumazenil; Heart Rate; Humans; Male; Midazolam; Minor Surgical Procedures; Narcotics; Randomized Controlled Trials as Topic; Respiration; Time Factors | 1990 |
Methohexital vs midazolam/flumazenil anaesthesia during laryngoscopy under jet ventilation.
Topics: Adult; Aged; Anesthesia, Intravenous; Arousal; Blood Pressure; Catecholamines; Consciousness; Female; Flumazenil; Heart Rate; High-Frequency Jet Ventilation; Humans; Laryngoscopy; Male; Methohexital; Midazolam; Middle Aged; Oximetry; Time Factors | 1990 |
Induction agents for day-case anaesthesia. A double-blind comparison of propofol and midazolam antagonised by flumazenil.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Double-Blind Method; Flumazenil; Humans; Male; Midazolam; Propofol; Psychomotor Performance; Randomized Controlled Trials as Topic | 1990 |
Double-blind study of the reversal of midazolam-induced sedation in the intensive care unit with flumazenil (Ro 15-1788): effect on weaning from ventilation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Care; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Randomized Controlled Trials as Topic; Ventilator Weaning | 1990 |
Reversal of midazolam sedation with flumazenil following conservative dentistry.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, General; Anesthesia, Intravenous; Chi-Square Distribution; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Postoperative Period; Psychomotor Performance; Randomized Controlled Trials as Topic | 1990 |
Psychomotor recovery after three methods of sedation during spinal anaesthesia.
Topics: Aged; Anesthesia Recovery Period; Anesthesia, Spinal; Double-Blind Method; Flicker Fusion; Flumazenil; Humans; Male; Memory, Short-Term; Midazolam; Preanesthetic Medication; Propofol; Prostatectomy; Psychomotor Performance; Randomized Controlled Trials as Topic | 1990 |
Flumazenil in the outpatient. A study following midazolam as sedation for upper gastrointestinal endoscopy.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Double-Blind Method; Endoscopy; Flicker Fusion; Flumazenil; Humans; Memory; Midazolam; Middle Aged; Prospective Studies; Psychomotor Performance; Randomized Controlled Trials as Topic; Reaction Time; Time Factors | 1990 |
Day-case surgery: enhanced recovery with flumazenil.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Female; Flumazenil; Humans; Lidocaine; Male; Midazolam; Middle Aged; Postoperative Period; Randomized Controlled Trials as Topic; Urologic Diseases | 1990 |
Flumazenil reverses sedation after midazolam-induced general anesthesia in ambulatory surgery patients.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, General; Double-Blind Method; Female; Flumazenil; Genital Diseases, Female; Humans; Midazolam; Randomized Controlled Trials as Topic | 1990 |
Effect of flumazenil on midazolam-induced amnesia.
Topics: Adult; Amnesia; Dose-Response Relationship, Drug; Flicker Fusion; Flumazenil; Humans; Memory; Midazolam; Time Factors | 1990 |
[Antagonizing the effect of midazolam by flumazenil in gastroscopy: results of a randomized double blind study].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arousal; Double-Blind Method; Female; Flumazenil; Gastroscopy; Humans; Male; Midazolam; Middle Aged; Preanesthetic Medication; Stomach Diseases | 1990 |
Flumazenil in ketamine and midazolam anaesthesia.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Double-Blind Method; Female; Flumazenil; Humans; Ketamine; Midazolam; Middle Aged; Patient Acceptance of Health Care; Postoperative Complications | 1990 |
Recovery from total intravenous anaesthesia. Propofol versus midazolam-flumazenil.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Arousal; Blood Pressure; Eyelashes; Flumazenil; Humans; Memory; Midazolam; Middle Aged; Motor Skills; Propofol; Reflex; Time Factors | 1990 |
Additional subcutaneous administration of flumazenil does not shorten recovery time after midazolam.
Topics: Adult; Double-Blind Method; Female; Flumazenil; Humans; Injections, Subcutaneous; Midazolam; Orientation; Randomized Controlled Trials as Topic; Reaction Time; Time Factors | 1990 |
Flumazenil used for antagonizing the central effects of midazolam and diazepam in outpatients.
Topics: Adult; Aged; Ambulatory Care; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Flumazenil; Gastroscopy; Humans; Male; Midazolam; Middle Aged; Random Allocation | 1989 |
Recovery from fixed-dose midazolam-induced anaesthesia and antagonism with flumazenil for outpatient arthroscopy.
Topics: Adolescent; Adult; Ambulatory Care; Anesthesia Recovery Period; Anesthetics; Arthroscopy; Clinical Trials as Topic; Flumazenil; Humans; Midazolam; Middle Aged; Random Allocation | 1989 |
[Acoustic and somatosensory evoked cortical potentials in sedation with midazolam and drug antagonism with flumazenil].
Topics: Adult; Arousal; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Female; Flumazenil; Hemodynamics; Humans; Male; Midazolam; Reaction Time; Respiration | 1989 |
Residual psychomotor effects following reversal of midazolam sedation with flumazenil.
Topics: Adult; Affect; Dizziness; Flumazenil; Heart Rate; Humans; Hypnotics and Sedatives; Locomotion; Male; Mental Recall; Midazolam; Neuropsychological Tests; Psychomotor Performance | 1989 |
[Does flumazenil, a benzodiazepine antagonist used during the anesthesia recovery period, have an anxiogenic effect?].
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anxiety; Epinephrine; Flumazenil; Humans; Midazolam; Middle Aged; Norepinephrine; Postoperative Complications; Postoperative Period; Psychometrics | 1989 |
Benzodiazepine antagonism does not provoke a stress response.
Topics: Adult; Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Flumazenil; Humans; Midazolam; Middle Aged; Random Allocation; Stress, Physiological | 1989 |
[Postoperative, opiate-induced respiratory depression is not dependent on arousal].
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Arousal; Arthroscopy; Clinical Trials as Topic; Female; Fentanyl; Flumazenil; Humans; Male; Midazolam; Oxygen; Postoperative Complications; Reflex, Startle; Respiration; Vecuronium Bromide | 1989 |
Fentanyl-midazolam-flumazenil anesthesia for induced abortion.
Topics: Abortion, Induced; Adolescent; Adult; Ambulatory Care Facilities; Anesthesia Recovery Period; Diazepam; Drug Therapy, Combination; Female; Fentanyl; Flumazenil; Humans; Ketamine; Meperidine; Midazolam; Pain Measurement; Pregnancy; Random Allocation | 1989 |
Flumazenil used in the antagonizing of diazepam and midazolam sedation in out-patients undergoing gastroscopy.
Topics: Adolescent; Adult; Aged; Diazepam; Double-Blind Method; Flumazenil; Gastroscopy; Humans; Midazolam; Middle Aged; Outpatients; Random Allocation; Receptors, GABA-A; Sleep | 1988 |
Effects of flumazenil on post-operative recovery after total intravenous anesthesia with midazolam and alfentanil.
Topics: Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Female; Fentanyl; Flumazenil; Humans; Hysterectomy; Midazolam; Postoperative Period; Receptors, GABA-A | 1988 |
The use of flumazenil after total i.v. anaesthesia with midazolam in out-patients.
Topics: Anesthesia, Intravenous; Flumazenil; Humans; Midazolam; Middle Aged; Outpatients; Receptors, GABA-A; Sleep | 1988 |
The relationship between dose and duration of action of intravenous flumazenil in reversing sedation induced by a continuous infusion of midazolam.
Topics: Adult; Dose-Response Relationship, Drug; Female; Flumazenil; Humans; Injections, Intravenous; Male; Midazolam; Receptors, GABA-A; Sleep; Time Factors | 1988 |
Pharmacodynamic interaction between midazolam and a specific benzodiazepine antagonist in humans.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Electroencephalography; Flumazenil; Half-Life; Humans; Liver Circulation; Male; Midazolam; Reaction Time | 1985 |
The efficacy of flumazenil versus physostigmine after midazolam-alfentanil anaesthesia in man.
Topics: Adult; Alfentanil; Anesthesia; Anesthesia Recovery Period; Double-Blind Method; Female; Fentanyl; Flumazenil; Humans; Male; Midazolam; Nitrous Oxide; Physostigmine; Random Allocation; Vecuronium Bromide | 1988 |
Clinical evaluation of a specific benzodiazepine antagonist (RO 15-1788). Studies in elderly patients after regional anaesthesia under benzodiazepine sedation.
Topics: Aged; Amnesia; Anesthesia Recovery Period; Anesthesia, Conduction; Benzodiazepines; Drug Evaluation; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Vital Capacity | 1986 |
Ro 15-1788 for postoperative recovery. A randomised clinical trial in patients undergoing minor surgical procedures under midazolam anaesthesia.
Topics: Abortion, Induced; Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Obstetrical; Benzodiazepines; Clinical Trials as Topic; Female; Flumazenil; Humans; Midazolam; Postoperative Period; Pregnancy; Random Allocation | 1986 |
Effects of a specific benzodiazepine antagonist (RO 15-1788) on cerebral blood flow.
Topics: Adult; Benzodiazepines; Cerebrovascular Circulation; Drug Interactions; Electroencephalography; Electromyography; Flumazenil; Hemodynamics; Humans; Male; Midazolam; Regional Blood Flow | 1987 |
Double-blind study of the reversal of midazolam-supplemented general anaesthesia with Ro 15-1788.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Clinical Trials as Topic; Double-Blind Method; Female; Flumazenil; Humans; Midazolam | 1987 |
Reversal of midazolam sedation with anexate.
Topics: Aged; Amnesia; Anesthesia Recovery Period; Anesthesia, Spinal; Flumazenil; Hemodynamics; Humans; Male; Midazolam; Orientation; Time Factors | 1987 |
[Assessment of the efficacy and tolerance of a benzodiazepine antagonist (Ro 15-1788)].
Topics: Adult; Benzodiazepines; Benzodiazepinones; Central Nervous System; Clinical Trials as Topic; Flumazenil; Hemodynamics; Humans; Injections, Intravenous; Male; Midazolam; Respiration | 1987 |
The effect of Ro15-1788 (Anexate) on conscious sedation produced with midazolam.
Topics: Adolescent; Adult; Anesthesia, Dental; Blood Pressure; Flumazenil; Humans; Hypnotics and Sedatives; Midazolam; Postoperative Complications; Tooth Extraction | 1987 |
Total intravenous anaesthesia with midazolam and flumazenil in outpatient clinics. A comparison with isoflurane or thiopentone.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Dilatation and Curettage; Electrocardiography; Female; Flumazenil; Humans; Isoflurane; Male; Midazolam; Middle Aged; Postoperative Complications; Thiopental; Time Factors | 1987 |
Comparison of propofol and antagonised midazolam anaesthesia for day-case surgery.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, General; Anesthesia, Intravenous; Anesthetics; Arousal; Clinical Trials as Topic; Cystoscopy; Double-Blind Method; Female; Flumazenil; Humans; Isoflurane; Male; Midazolam; Middle Aged; Nitrous Oxide; Phenols; Propofol; Psychomotor Performance; Random Allocation | 1987 |
[Clinical evaluation of flumazenil (Anexate) on the recovery parameters following the administration of 3 benzodiazepines (flunitrazepam, midazolam or diazepam].
Topics: Adult; Aged; Analgesics; Anesthesia Recovery Period; Anesthesia, General; Benzodiazepines; Diazepam; Drug Evaluation; Female; Flumazenil; Flunitrazepam; Humans; Male; Midazolam; Middle Aged; Postoperative Period; Prospective Studies; Random Allocation; Respiration | 1987 |
[The effectiveness of the benzodiazepine antagonist Ro 15-1788 after the induction of anesthesia with midazolam].
Topics: Adult; Anesthesia; Anesthesia Recovery Period; Double-Blind Method; Drug Evaluation; Female; Flumazenil; Humans; Memory; Midazolam; Preanesthetic Medication; Random Allocation; Time Factors | 1988 |
[Postoperative reversal of loss of vigilance following midazolam with the use of the antagonist flumazenil (Ro 15-1788). A comparative study with a placebo and the use of EEG-power spectra].
Topics: Adult; Arousal; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Flumazenil; Humans; Midazolam; Postoperative Complications; Random Allocation; Time Factors | 1988 |
The use of flumazenil as an antagonist to midazolam in intravenous sedation for dental procedures.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Dentistry, Operative; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Postoperative Care | 1988 |
Flumazenil in total intravenous anaesthesia using midazolam and fentanyl.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Clinical Trials as Topic; Double-Blind Method; Female; Fentanyl; Flumazenil; Humans; Male; Midazolam; Middle Aged; Random Allocation | 1988 |
Effects of the benzodiazepine antagonist flumazenil on postoperative performance following total intravenous anaesthesia with midazolam and alfentanil.
Topics: Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Cooperative Behavior; Female; Fentanyl; Flumazenil; Humans; Memory; Midazolam; Nitrous Oxide; Orientation; Postoperative Period; Thiopental | 1988 |
Pharmacokinetics of midazolam and alfentanil in outpatient general anesthesia. A study with concomitant thiopentone, flumazenil or placebo administration.
Topics: Adult; Alfentanil; Ambulatory Surgical Procedures; Anesthesia, General; Female; Fentanyl; Flumazenil; Humans; Midazolam; Middle Aged; Nitrous Oxide; Placebos; Preanesthetic Medication; Thiopental; Time Factors | 1988 |
[Effectiveness and tolerance of flumazenil in regional anesthesia with midazolam sedation].
Topics: Adult; Aged; Anesthesia, Epidural; Anesthesia, Spinal; Arousal; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Flumazenil; Humans; Midazolam; Middle Aged; Preanesthetic Medication | 1988 |
Antagonism of midazolam sedation by flumazenil: a placebo-controlled study in patients recovering from intravenous anaesthesia with high doses of midazolam.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Clinical Trials as Topic; Female; Flumazenil; Humans; Male; Midazolam; Placebos; Preanesthetic Medication; Random Allocation | 1988 |
Electrophysiological aspects of benzodiazepine antagonists, Ro 15-1788 and Ro 15-3505.
Topics: Adult; Benzodiazepines; Benzodiazepinones; Electroencephalography; Flumazenil; Humans; Male; Midazolam | 1984 |
Sedative and ventilatory effects of midazolam infusion: effect of flumazenil reversal.
Topics: Adult; Ambulatory Care; Anesthetics, Intravenous; Double-Blind Method; Female; Fentanyl; Flumazenil; Humans; Hypercapnia; Hypnotics and Sedatives; Infusions, Intravenous; Male; Midazolam; Middle Aged; Pulmonary Alveoli; Respiration; Respiratory Dead Space; Sodium Chloride; Tidal Volume | 1995 |
Pharmacodynamic modeling of the electroencephalographic effects of flumazenil in healthy volunteers sedated with midazolam.
Topics: Adult; Electroencephalography; Flumazenil; Fourier Analysis; GABA Modulators; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Models, Biological | 1995 |
[The effect of flumazenil in reversing midazolam, flunitrazepam or diazepam].
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, Spinal; Diazepam; Female; Flumazenil; Flunitrazepam; Hemodynamics; Humans; Male; Midazolam; Middle Aged; Respiration | 1995 |
A random trial comparing recovery after midazolam-alfentanil anesthesia with and without reversal with flumazenil, and standardized neurolept anesthesia for major gynecologic surgery.
Topics: Adult; Aged; Alfentanil; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Double-Blind Method; Female; Flumazenil; Genitalia, Female; Heart Rate; Humans; Midazolam; Middle Aged; Neuroleptanalgesia; Nitrous Oxide; Placebos; Respiration | 1995 |
Comparison of the recovery characteristics of midazolam, alone or antagonised with flumazenil, and thiopental in ASA III-IV patients.
Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Intravenous; Aortography; Cognition; Double-Blind Method; Flumazenil; Humans; Male; Memory; Midazolam; Middle Aged; Orientation; Psychomotor Performance; Sleep Stages; Thiopental; Wakefulness | 1995 |
Sedation with midazolam during regional anaesthesia: is there a role for flumazenil?
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Epidural; Conscious Sedation; Double-Blind Method; Elective Surgical Procedures; Female; Flicker Fusion; Flumazenil; Follow-Up Studies; Humans; Male; Midazolam; Middle Aged; Placebos; Psychomotor Performance; Wakefulness | 1994 |
[Effect of continuous infusion of flumazenil on unexpected postoperative resedation by midazolam].
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Arousal; Female; Flumazenil; Humans; Infusions, Intravenous; Male; Midazolam; Middle Aged | 1994 |
Flumazenil exerts intrinsic activity on sleep EEG and nocturnal hormone secretion in normal controls.
Topics: Adult; Electrocardiography; Electroencephalography; Flumazenil; Growth Hormone; Hormones; Humans; Hydrocortisone; Male; Midazolam; Sleep; Wakefulness | 1994 |
Effectiveness of flumazenil on return of cognitive functions after a general anesthetic.
Topics: Adult; Anesthesia, General; Cognition; Double-Blind Method; Flumazenil; Humans; Memory; Midazolam | 1994 |
The pharmacokinetic-pharmacodynamic (Digit Symbol Substitution Test) relationship of flumazenil in a midazolam steady-state model in healthy volunteers.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Flumazenil; Humans; Male; Midazolam; Psychomotor Performance | 1994 |
Midazolam/propofol but not propofol alone reversibly depress the swallowing reflex.
Topics: Ambulatory Care; Anesthesia, Intravenous; Awareness; Colonoscopy; Deglutition; Depression, Chemical; Double-Blind Method; Drug Combinations; Electromyography; Flumazenil; Humans; Hyoid Bone; Midazolam; Placebos; Propofol; Reaction Time; Reflex | 1994 |
Effect of flumazenil on recovery after midazolam and propofol sedation.
Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Cognition; Conscious Sedation; Female; Flumazenil; Humans; Midazolam; Middle Aged; Monitoring, Intraoperative; Propofol; Psychomotor Performance | 1994 |
The use of midazolam and flumazenil for invasive radiographic procedures.
Topics: Aged; Anesthesia Recovery Period; Angiography; Aortography; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged | 1993 |
The effect of intravenously administered diazepam, midazolam and flumazenil on the sensitivity of upper airway reflexes.
Topics: Adult; Ammonia; Diazepam; Double-Blind Method; Flumazenil; Gagging; Humans; Injections, Intravenous; Male; Midazolam; Reaction Time; Time Factors | 1994 |
Effect of flumazenil on the recovery from intravenous midazolam.
Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Dental; Conscious Sedation; Flicker Fusion; Flumazenil; Humans; Infusions, Intravenous; Midazolam; Molar, Third; Oxygen; Reaction Time; Tooth Extraction | 1994 |
Absence of agonist effects of high-dose flumazenil on ventilation and psychometric performance in human volunteers.
Topics: Adult; Depression, Chemical; Double-Blind Method; Flumazenil; Humans; Injections, Intravenous; Male; Midazolam; Psychomotor Performance; Reference Values; Respiration | 1993 |
Evaluation of flumazenil for reversing the effects of midazolam-induced conscious sedation or general anesthesia.
Topics: Adult; Anesthesia, General; Conscious Sedation; Double-Blind Method; Female; Fentanyl; Flumazenil; Humans; Male; Mental Recall; Midazolam; Middle Aged; Multivariate Analysis; Psychomotor Performance; Wakefulness | 1993 |
The effects of large-dose flumazenil on midazolam-induced ventilatory depression.
Topics: Adolescent; Adult; Depression, Chemical; Double-Blind Method; Flumazenil; Humans; Male; Midazolam; Middle Aged; Respiration | 1993 |
The interactions of midazolam and flumazenil on human memory and cognition.
Topics: Adolescent; Adult; Analysis of Variance; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Flumazenil; Humans; Male; Memory; Midazolam; Prospective Studies | 1993 |
The effect of flumazenil on midazolam-induced depression of the ventilatory response to hypoxia during isohypercarbia.
Topics: Adult; Depression, Chemical; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Flumazenil; Humans; Hypercapnia; Hypoxia; Male; Midazolam; Respiration | 1993 |
Recovery from intravenous sedation with midazolam--the value of flumazenil.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Dental; Chi-Square Distribution; Conscious Sedation; Consciousness; Flumazenil; Humans; Midazolam; Molar, Third; Postoperative Care; Psychomotor Performance; Single-Blind Method; Time Factors; Tooth Extraction | 1993 |
Evaluation of sedation in quail induced by use of midazolam and reversed by use of flumazenil.
Topics: Animals; Anti-Anxiety Agents; Colinus; Consciousness; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Heart; Hypnotics and Sedatives; Lung; Midazolam; Prospective Studies | 1996 |
Effect of flumazenil on ventilatory drive during sedation with midazolam and alfentanil.
Topics: Adult; Alfentanil; Analgesics, Opioid; Antidotes; Benzodiazepines; Carbon Dioxide; Conscious Sedation; Consciousness; Cross-Over Studies; Depression, Chemical; Double-Blind Method; Drug Interactions; Female; Flumazenil; Humans; Hypnotics and Sedatives; Hypoxia; Infusions, Intravenous; Male; Midazolam; Respiration | 1996 |
Flumazenil reversal of psychomotor impairment due to midazolam or diazepam for conscious sedation for upper endoscopy.
Topics: Adult; Aged; Aged, 80 and over; Akathisia, Drug-Induced; Anesthetics, Intravenous; Antidotes; Chi-Square Distribution; Conscious Sedation; Diazepam; Duodenoscopy; Esophagoscopy; Female; Flumazenil; Gastroscopy; Humans; Male; Midazolam; Middle Aged; Treatment Outcome | 1996 |
Benzodiazepine site pharmacokinetic/pharmacodynamic quantification in man: direct measurement of drug occupancy and effects on the human brain in vivo.
Topics: Adult; Benzodiazepines; Brain; Electroencephalography; Flumazenil; GABA Modulators; Humans; Male; Midazolam; Middle Aged; Models, Biological; Receptors, GABA-A; Saccades; Tomography, Emission-Computed | 1996 |
The effects of midazolam and flumazenil on psychomotor function.
Topics: Adjuvants, Anesthesia; Adult; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Humans; Male; Midazolam; Perception; Psychometrics; Psychomotor Performance; Reaction Time | 1997 |
Midazolam-flumazenil topical anaesthesia for microlaryngoscopy with jet ventilation.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Benzodiazepines; Blood Pressure; Child; Double-Blind Method; Flumazenil; High-Frequency Jet Ventilation; Humans; Laryngoscopy; Midazolam; Middle Aged | 1997 |
Safety and efficacy of flumazenil in reversing conscious sedation in the emergency department. Emergency Medicine Conscious Sedation Study Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidotes; Arousal; Conscious Sedation; Consciousness; Dose-Response Relationship, Drug; Double-Blind Method; Emergency Service, Hospital; Female; Flumazenil; Humans; Male; Memory; Midazolam; Middle Aged; Statistics, Nonparametric; Treatment Outcome | 1997 |
Safety and efficacy of flumazenil in the reversal of benzodiazepine-induced conscious sedation. The Flumazenil Pediatric Study Group.
Topics: Adolescent; Antidotes; Benzodiazepines; Child; Child, Preschool; Conscious Sedation; Flumazenil; Humans; Infant; Midazolam; Retrospective Studies | 1997 |
Midazolam versus diazepam in lipid emulsion as conscious sedation for colonoscopy with or without reversal of sedation with flumazenil.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Combined; Anesthetics, Intravenous; Antidotes; Colonoscopy; Conscious Sedation; Diazepam; Double-Blind Method; Fat Emulsions, Intravenous; Female; Flumazenil; Humans; Logistic Models; Male; Midazolam; Middle Aged; Pain; Pain Measurement; Patient Satisfaction | 1998 |
Acute tolerance and reversal of the motor control effects of midazolam.
Topics: Adult; Anti-Anxiety Agents; Double-Blind Method; Drug Tolerance; Female; Flumazenil; GABA Modulators; Heart Rate; Humans; Infusions, Intravenous; Isometric Contraction; Male; Midazolam; Psychomotor Performance | 1998 |
Midazolam-flumazenil versus propofol anaesthesia for scoliosis surgery with wake-up tests.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Antidotes; Arousal; Child; Drug Costs; Evoked Potentials, Somatosensory; Female; Flumazenil; Humans; Intraoperative Care; Intubation, Intratracheal; Male; Memory; Midazolam; Monitoring, Intraoperative; Naloxone; Narcotic Antagonists; Pain; Postoperative Care; Propofol; Prospective Studies; Psychomotor Performance; Scoliosis; Spinal Cord; Wakefulness | 1998 |
Impact of flumazenil on recovery after outpatient endoscopy: a placebo-controlled trial.
Topics: Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Benzodiazepines; Chi-Square Distribution; Conscious Sedation; Cost-Benefit Analysis; Double-Blind Method; Endoscopy, Gastrointestinal; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Placebos; Prospective Studies | 1999 |
Postoperative obstructive apnea.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Diaphragm; Electromyography; Flumazenil; GABA Modulators; Humans; Male; Midazolam; Muscle Contraction; Muscle Tonus; Postoperative Complications; Preoperative Care; Respiratory Muscles; Sleep Apnea Syndromes | 1999 |
The effect of flumazenil on patient recovery and discharge following ambulatory surgery.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthetics, Intravenous; Antidotes; Convalescence; Double-Blind Method; Female; Flumazenil; Humans; Length of Stay; Male; Midazolam; Middle Aged; Prospective Studies | 1999 |
Flumazenil antagonizes midazolam-induced airway narrowing during nasal breathing in humans.
Topics: Adult; Airway Obstruction; Airway Resistance; Anti-Anxiety Agents; Apnea; Female; Flumazenil; GABA Modulators; Humans; Male; Midazolam; Snoring | 1999 |
Flumazenil discrimination by humans under a two-response and a novel-response procedure.
Topics: Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Humans; Male; Midazolam; Psychomotor Performance; Triazolam | 1999 |
Pharmacoeconomic evaluation of flumazenil for routine outpatient EGD.
Topics: Adult; Ambulatory Care; Anesthesia Recovery Period; Attitude of Health Personnel; Cost-Benefit Analysis; Double-Blind Method; Endoscopy, Gastrointestinal; Female; Flumazenil; Hospital Charges; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Patient Satisfaction; Recovery Room; Time Factors | 2000 |
Cardiovascular response and stress reaction to flumazenil injection in patients under infusion with midazolam.
Topics: Acute Disease; Adolescent; Adult; Aged; Antidotes; Conscious Sedation; Consciousness; Drug Monitoring; Epinephrine; Female; Flumazenil; GABA Modulators; Hemodynamics; Humans; Hydrocortisone; Hypnotics and Sedatives; Infusions, Intravenous; Injections, Intravenous; Male; Midazolam; Middle Aged; Norepinephrine; Prospective Studies; Stress, Physiological; Sulfotransferases | 2000 |
The effects of midazolam and flumazenil on psychomotor function and alertness in human volunteers.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetics, Intravenous; Arousal; Conscious Sedation; Cross-Over Studies; Double-Blind Method; Female; Flumazenil; GABA Modulators; Humans; Male; Midazolam; Psychomotor Performance; Reaction Time | 2000 |
Physostigmine reversal of midazolam-induced electroencephalographic changes in healthy subjects.
Topics: Adult; Analysis of Variance; Antidotes; Brain; Cholinesterase Inhibitors; Chromatography, Liquid; Cross-Over Studies; Double-Blind Method; Electroencephalography; Flumazenil; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Midazolam; Physostigmine; Reference Values | 2000 |
Flumazenil abolishes midazolam-induced increase in the work of nasal breathing.
Topics: Adult; Air Pressure; Airway Resistance; Anesthetics, Intravenous; Antidotes; Female; Flumazenil; Humans; Laryngeal Masks; Male; Midazolam; Respiratory Function Tests; Respiratory Mechanics; Work of Breathing | 2000 |
Effect of flumazenil on electroencephalographic patterns induced by midazolam.
Topics: Adolescent; Adult; Electroencephalography; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam | 2000 |
A comparison of intramuscular ketamine with high dose intramuscular midazolam with and without intranasal flumazenil in children before suturing.
Topics: Administration, Intranasal; Child; Child, Preschool; Conscious Sedation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emergency Service, Hospital; Female; Flumazenil; Humans; Infant; Injections, Intramuscular; Ketamine; Male; Midazolam; Sutures; Wounds and Injuries | 2001 |
The effects of flumazenil on sleepiness, task performance and nocturnal sleep after anesthesia with midazolam.
Topics: Adult; Anesthetics, Intravenous; Disorders of Excessive Somnolence; Flumazenil; GABA Modulators; Humans; Male; Midazolam; Polysomnography; Sleep Stages | 2001 |
A small dose of midazolam decreases the time to achieve hypnosis without delaying emergence during short-term propofol anesthesia.
Topics: Adjuvants, Anesthesia; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flumazenil; GABA Modulators; Hemodynamics; Humans; Male; Midazolam; Middle Aged; Propofol; Prospective Studies | 2001 |
Use of dynamic negative airway pressure (DNAP) to assess sedative-induced upper airway obstruction.
Topics: Adult; Air Pressure; Airway Obstruction; Arousal; Carbon Dioxide; Female; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Male; Midazolam; Ventilators, Negative-Pressure | 2002 |
Short-term effects of intravenous benzodiazepines on autonomic neurocardiac regulation in humans: a comparison between midazolam, diazepam, and lorazepam.
Topics: Adult; Autonomic Nervous System; Benzodiazepines; Diazepam; Female; Flumazenil; Heart; Heart Rate; Humans; Injections, Intravenous; Lorazepam; Male; Midazolam; Middle Aged; Preanesthetic Medication; Prospective Studies | 2002 |
The effect of intravenous administration of variable-dose flumazenil after fixed-dose ketamine and midazolam in healthy cats.
Topics: Anesthetics, Intravenous; Animals; Antidotes; Behavior, Animal; Cats; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; Injections, Intravenous; Ketamine; Male; Midazolam; Reference Values | 2002 |
A randomised, controlled trial of cognitive and psychomotor recovery from midazolam sedation following reversal with oral flumazenil.
Topics: Administration, Oral; Adult; Affect; Anesthesia Recovery Period; Antidotes; Attention; Cognition; Conscious Sedation; Cross-Over Studies; Dental Anxiety; Double-Blind Method; Flumazenil; Humans; Hypnotics and Sedatives; Memory, Short-Term; Midazolam; Middle Aged; Postoperative Care; Psychometrics; Psychomotor Performance; Reaction Time | 2002 |
Flumazenil reduces midazolam-induced cognitive impairment without altering pharmacokinetics.
Topics: Adult; Anti-Anxiety Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, Liquid; Cognition; Cross-Over Studies; Cytochrome P-450 CYP3A; Double-Blind Method; Drug Interactions; Flumazenil; Humans; Infusions, Intravenous; Liver; Male; Mass Spectrometry; Midazolam; Middle Aged; Oxidoreductases, N-Demethylating; Phenotype; Reference Values; Time Factors | 2002 |
Sedation for cardioversion in the emergency department: analysis of effectiveness in four protocols.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Clinical Protocols; Conscious Sedation; Drug Therapy, Combination; Electric Countershock; Emergency Medical Services; Etomidate; Female; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Myoclonus; Outcome and Process Assessment, Health Care; Propofol; Prospective Studies; Treatment Outcome | 2003 |
A randomised crossover trial of post-operative cognitive and psychomotor recovery from benzodiazepine sedation: effects of reversal with flumazenil over a prolonged recovery period.
Topics: Adolescent; Adult; Affect; Anesthesia Recovery Period; Antidotes; Attention; Choice Behavior; Cognition; Cross-Over Studies; Double-Blind Method; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Memory; Midazolam; Middle Aged; Placebos; Prospective Studies; Psychomotor Performance; Reaction Time | 2002 |
[Utility of routine use of reversion after sedation in outpatient colonoscopy].
Topics: Ambulatory Surgical Procedures; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Meperidine; Midazolam; Middle Aged; Prospective Studies | 2005 |
GABA-benzodiazepine receptor function in alcohol dependence: a combined 11C-flumazenil PET and pharmacodynamic study.
Topics: Adult; Alcoholism; Analysis of Variance; Blood Pressure; Brain; Case-Control Studies; Competitive Bidding; Electroencephalography; Flumazenil; GABA Modulators; Heart Rate; Humans; Image Processing, Computer-Assisted; Male; Midazolam; Middle Aged; Pain Measurement; Positron-Emission Tomography; Receptors, GABA-A; Saccades; Severity of Illness Index; Sleep; Test Anxiety Scale; Time Factors; Tritium | 2005 |
Effect of flumazenil on recovery from sevoflurane anesthesia in children premedicated with oral midazolam before undergoing herniorrhaphy with or without caudal analgesia.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool; Digestive System Surgical Procedures; Double-Blind Method; Female; Flumazenil; GABA Modulators; Herniorrhaphy; Humans; Hypnotics and Sedatives; Infant; Male; Methyl Ethers; Midazolam; Preanesthetic Medication; Psychomotor Agitation; Sevoflurane | 2005 |
Midazolam for patients undergoing upper gastrointestinal endoscopy: a prospective, single-blind and randomized study to determine the appropriate amount and time of initiation of endoscopy.
Topics: Analysis of Variance; Antidotes; Double-Blind Method; Female; Flumazenil; Gastroscopy; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Midazolam; Middle Aged; Patient Satisfaction; Prospective Studies; Single-Blind Method; Time Factors; Treatment Outcome | 2005 |
Sedative effects of midazolam and xylazine with or without ketamine and detomidine alone following intranasal administration in Ring-necked Parakeets.
Topics: Administration, Intranasal; Adrenergic alpha-Antagonists; Animals; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Female; Flumazenil; Heart Rate; Hypnotics and Sedatives; Imidazoles; Ketamine; Male; Midazolam; Parakeets; Prospective Studies; Respiration; Time Factors; Treatment Outcome; Xylazine; Yohimbine | 2006 |
Clinical evaluation of intranasal benzodiazepines, alpha-agonists and their antagonists in canaries.
Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Behavior, Animal; Benzodiazepines; Canaries; Diazepam; Drug Therapy, Combination; Female; Flumazenil; Hypnotics and Sedatives; Imidazoles; Male; Midazolam; Prospective Studies; Xylazine; Yohimbine | 2006 |
Effect of flumazenil on disturbance of equilibrium function induced by midazolam.
Topics: Adult; Anesthesia, Dental; Conscious Sedation; Delayed Emergence from Anesthesia; Diagnosis, Computer-Assisted; Dose-Response Relationship, Drug; Double-Blind Method; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Injections, Intravenous; Midazolam; Postural Balance; Prospective Studies; Young Adult | 2008 |
Effect of intravenous flumazenil on oral midazolam pharmacokinetics and pharmacodynamics for use as a cytochrome P450 3A probe.
Topics: Administration, Oral; Adult; Cross-Over Studies; Cytochrome P-450 CYP3A; Double-Blind Method; Drug Interactions; Female; Flumazenil; GABA Modulators; Humans; Injections, Intravenous; Male; Maze Learning; Midazolam; Middle Aged; Neuropsychological Tests; Phenotype; Sex Factors; Therapeutic Equivalency | 2009 |
Midazolam increases bite force during intravenous sedation.
Topics: Adult; Anesthesia, Intravenous; Awareness; Bite Force; Blood Pressure; Conscious Sedation; Cross-Over Studies; Electroencephalography; Flumazenil; GABA Modulators; Hand Strength; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Muscle Strength; Oxygen; Respiration | 2012 |
Sedation and physiologic response to manual restraint after intranasal administration of midazolam in Hispaniolan Amazon parrots (Amazona ventralis).
Topics: Administration, Intranasal; Amazona; Animals; Antidotes; Behavior, Animal; Body Temperature; Cross-Over Studies; Flumazenil; Hypnotics and Sedatives; Midazolam; Respiratory Physiological Phenomena; Restraint, Physical; Time Factors | 2012 |
The combined effects of midazolam and propofol sedation on muscle power.
Topics: Adult; Bite Force; Conscious Sedation; Consciousness Monitors; Cross-Over Studies; Flumazenil; Hand Strength; Humans; Hypnotics and Sedatives; Injections, Intravenous; Male; Midazolam; Muscle Strength; Muscle Strength Dynamometer; Muscle, Skeletal; Neuropsychological Tests; Propofol; Sample Size; Stroop Test | 2013 |
Injection anaesthesia with fentanyl-midazolam-medetomidine in adult female mice: importance of antagonization and perioperative care.
Topics: Analgesics; Anesthetics, Combined; Animals; Body Temperature; Female; Fentanyl; Flumazenil; Heart Rate; Imidazoles; Injections, Intraperitoneal; Medetomidine; Mice; Mice, Inbred C57BL; Midazolam; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Perioperative Care | 2016 |
Inhalation of 50% Oxygen Does Not Impair Respiratory Depression During Midazolam Sedation.
Topics: Adult; Antidotes; Capnography; Conscious Sedation; Cross-Over Studies; Female; Flumazenil; Healthy Volunteers; Humans; Hypnotics and Sedatives; Male; Midazolam; Oximetry; Oxygen; Respiratory Insufficiency; Respiratory Rate; Single-Blind Method; Tidal Volume | 2016 |
Efficacy and safety of flumazenil injection for the reversal of midazolam sedation after elective outpatient endoscopy.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Conscious Sedation; Elective Surgical Procedures; Endoscopy, Gastrointestinal; Female; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Injections, Intravenous; Male; Midazolam; Middle Aged; Pain, Postoperative; Prospective Studies; Young Adult | 2018 |
Use of Rodent Sedation Tests to Evaluate Midazolam and Flumazenil in Green Iguanas (
Topics: Animals; Antidotes; Female; Flumazenil; Hypnotics and Sedatives; Iguanas; Laboratory Animal Science; Male; Midazolam | 2019 |
Evaluation of alfaxalone and midazolam with or without flumazenil reversal in Egyptian fruit bats (Rousettus aegyptiacus).
Topics: Animals; Chiroptera; Flumazenil; Male; Midazolam; Pregnanediones | 2021 |
EVALUATION OF THE EFFECTS OF MIDAZOLAM AND FLUMAZENIL IN THE BALL PYTHON (
Topics: Animals; Boidae; Cross-Over Studies; Female; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Midazolam | 2019 |
A Pharmacokinetic-Pharmacodynamic Study of Intravenous Midazolam and Flumazenil in Adult New Zealand White-Californian Rabbits (
Topics: Administration, Intravenous; Animals; Cross-Over Studies; Flumazenil; Midazolam; Prospective Studies; Rabbits | 2021 |
334 other study(ies) available for midazolam and flumazenil
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
In vivo characterization of the pharmacodynamic interaction of a benzodiazepine agonist and antagonist: midazolam and flumazenil.
Topics: Animals; Benzodiazepines; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Flumazenil; Male; Midazolam; Models, Biological; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Modulation of decay kinetics and frequency of GABAA receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Anesthetics, Local; Animals; Calcium Channels; Evoked Potentials; Flumazenil; Hippocampus; Kinetics; Lidocaine; Mathematics; Meglumine; Membrane Potentials; Midazolam; Models, Neurological; Neurons; Pentobarbital; Probability; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA-A; Synapses; Tetrodotoxin | 1992 |
Dissociation between the effects of benzodiazepine receptor agonists on behavioral vigilance and responsitivity.
Topics: Animals; Anti-Anxiety Agents; Arousal; Behavior, Animal; Carbolines; Chlordiazepoxide; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Agonists; Male; Midazolam; Rats; Rats, Sprague-Dawley | 1992 |
IFDAS Research Council Report 1988-91: Midazolam.
Topics: Anesthesia, Dental; Conscious Sedation; Drug Combinations; Flumazenil; Humans; Midazolam; Nalbuphine; Pentazocine; Societies, Dental | 1992 |
Yohimbine/flumazenil antagonism of hemodynamic alterations induced by a combination of midazolam, xylazine, and butorphanol in dogs.
Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Butorphanol; Cardiac Output; Dogs; Female; Flumazenil; Heart Rate; Hemodynamics; Male; Midazolam; Stroke Volume; Vascular Resistance; Xylazine; Yohimbine | 1992 |
Tolerance, cross-tolerance and withdrawal in rats made dependent on diazepam.
Topics: Animals; Chlordiazepoxide; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Drug Tolerance; Flumazenil; Male; Midazolam; Pentylenetetrazole; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1992 |
Relative effects of intrathecal administration of fentanyl and midazolam on A delta and C fibre reflexes.
Topics: Anesthesia, Spinal; Animals; Dogs; Electric Stimulation; Fentanyl; Flumazenil; Kidney; Midazolam; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Reflex; Sympathetic Nervous System; Tibial Nerve | 1992 |
Flumazenil in mixed benzodiazepine/tricyclic antidepressant overdose: a placebo-controlled study in the dog.
Topics: Amitriptyline; Animals; Arrhythmias, Cardiac; Dogs; Drug Interactions; Drug Overdose; Electrocardiography; Female; Flumazenil; Heart; Male; Midazolam; Placebos; Seizures | 1992 |
EEG and auditory evoked potential P300 compared with psychometric tests in assessing vigilance after benzodiazepine sedation and antagonism.
Topics: Adult; Arousal; Conscious Sedation; Electroencephalography; Evoked Potentials, Auditory, Brain Stem; Female; Flumazenil; Humans; Male; Midazolam; Psychometrics | 1992 |
Comparison of the discriminative stimulus effects of midazolam after intracranial and peripheral administration in the rat.
Topics: Animals; Discrimination Learning; Flumazenil; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Midazolam; Rats; Receptors, GABA-A | 1991 |
Reversal by naloxone of spinal antinociceptive effects of fentanyl, ketocyclazocine and midazolam.
Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Ethylketocyclazocine; Fentanyl; Flumazenil; Injections, Spinal; Lumbar Vertebrae; Male; Midazolam; Naloxone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Sensory Thresholds | 1991 |
Midazolam withdrawal and discriminative motor control: effects of FG 7142 and Ro 15-1788.
Topics: Animals; Brain Chemistry; Carbolines; Discrimination, Psychological; Dose-Response Relationship, Drug; Drinking Behavior; Flumazenil; GABA-A Receptor Antagonists; Male; Midazolam; Rats; Reinforcement Schedule; Substance Withdrawal Syndrome; Substance-Related Disorders | 1991 |
Pharmacology of saccadic eye movements in man. 1. Effects of the benzodiazepine receptor ligands midazolam and flumazenil.
Topics: Adult; Dose-Response Relationship, Drug; Electrooculography; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam; Receptors, GABA-A; Saccades | 1991 |
Behavioral effects of benzodiazepine ligands in non-dependent, diazepam-dependent and diazepam-withdrawn baboons.
Topics: Animals; Behavior, Animal; Benzodiazepines; Carbolines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Ligands; Male; Midazolam; Papio; Receptors, GABA-A; Social Behavior; Substance Withdrawal Syndrome; Substance-Related Disorders | 1991 |
I.F.D.A.S. Research Council Report 1988-91.
Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, Dental; Blood Pressure; Conscious Sedation; Female; Flumazenil; Heart Rate; Humans; Male; Midazolam; Middle Aged; Respiration | 1991 |
Short-term anesthesia with midazolam and flumazenil during intraluminal afterloading of esophageal and bronchial neoplasms in ill, inoperable patients.
Topics: Anesthesia, Intravenous; Bronchial Neoplasms; Esophageal Neoplasms; Flumazenil; Humans; Iridium Radioisotopes; Midazolam; Palliative Care | 1990 |
Transurethral resection of prostate under sedation and local anesthesia (sedoanalgesia). Experience in 100 patients.
Topics: Aged; Anesthesia, Local; Conscious Sedation; Flumazenil; Humans; Lidocaine; Male; Midazolam; Prostatectomy; Prostatic Hyperplasia; Time Factors; Urethral Obstruction; Urinary Retention | 1991 |
Benzodiazepines and pain: effects of midazolam on the activities of nociceptive non-specific dorsal horn neurons in the rat spinal cord.
Topics: Analysis of Variance; Animals; Electric Stimulation; Flumazenil; Male; Midazolam; Nerve Fibers; Neurons; Nociceptors; Pain; Physical Stimulation; Rats; Rats, Inbred Strains; Spinal Cord; Time Factors | 1992 |
[Use of flumazenil to reverse the effects of midazolam in children].
Topics: Adolescent; Age Factors; Anxiety; Child; Child, Preschool; Flumazenil; Humans; Hypnotics and Sedatives; Infant; Midazolam | 1991 |
Antagonism of benzodiazepine sedation with flumazenil.
Topics: Anesthesia Recovery Period; Flumazenil; Humans; Midazolam | 1991 |
Physostigmine is equipotent to flumazenil only in excessive doses, while naloxone is ineffective in reversing midazolam anesthesia.
Topics: Animals; Flumazenil; Male; Midazolam; Naloxone; Physostigmine; Rats; Rats, Inbred Strains | 1991 |
Anxiolytic effect of midazolam microinjected into the dorsal periaqueductal grey area of rats.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Drug Synergism; Electric Stimulation; Flumazenil; Male; Microinjections; Midazolam; Periaqueductal Gray; Rats; Rats, Inbred Strains | 1991 |
[Anesthesia for thalamic stimulations: value of flumazenil].
Topics: Adult; Aged; Anesthesia, General; Electric Stimulation; Flumazenil; Humans; Intraoperative Period; Male; Midazolam; Middle Aged; Neuralgia; Parkinson Disease; Stereotaxic Techniques; Thalamus; Tremor | 1991 |
Reversing intravenous sedation with flumazenil.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Awareness; Cognition; Conscious Sedation; Consciousness; Female; Flumazenil; Humans; Male; Mental Recall; Meperidine; Midazolam; Middle Aged; Placebos; Psychomotor Performance; Time Factors | 1991 |
Rapid transition from methadone maintenance to naltrexone.
Topics: Flumazenil; Humans; Methadone; Midazolam; Naltrexone; Substance Withdrawal Syndrome | 1990 |
The effect of the benzodiazepine antagonist flumazenil on microfilariae of Monanema martini in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Filarioidea; Flumazenil; Microfilariae; Midazolam; Movement | 1990 |
Benzodiazepines and synaptic processing in the spatial domain within the cat's primary somatosensory cortex.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Cats; Diazepam; Electric Stimulation; Electrophysiology; Female; Flumazenil; Fluphenazine; gamma-Aminobutyric Acid; Male; Midazolam; Physical Stimulation; Somatosensory Cortex; Space Perception; Synapses | 1990 |
Which agent and how to deliver it? A review of benzodiazepine sedation and its reversal in endoscopy.
Topics: Analgesics, Opioid; Anti-Anxiety Agents; Conscious Sedation; Diazepam; Endoscopy, Gastrointestinal; Flumazenil; Humans; Midazolam | 1990 |
Benzodiazepine-induced antagonism of opioid antinociception may be abolished by spinalization or blockade of the benzodiazepine receptor.
Topics: Analgesics; Animals; Anti-Anxiety Agents; Diazepam; Flumazenil; Male; Mice; Midazolam; Morphine; Narcotics; Nordazepam; Psychomotor Performance; Reaction Time; Receptors, GABA-A; Receptors, Opioid; Skin Temperature; Spinal Cord | 1990 |
Flumazenil in intensive care. The duration of arousal after an assessment dose.
Topics: Adult; Aged; Aged, 80 and over; Arousal; Conscious Sedation; Critical Care; Drug Administration Schedule; Female; Flumazenil; Hemodynamics; Humans; Male; Midazolam; Middle Aged; Time Factors; Ventilator Weaning | 1991 |
Intraocular pressure in anaesthetized dogs given flumazenil with and without prior administration of midazolam.
Topics: Anesthesia, Inhalation; Animals; Aqueous Humor; Blood Pressure; Dogs; Flumazenil; Injections, Intravenous; Intraocular Pressure; Midazolam; Ocular Hypertension | 1991 |
Resedation after bolus administration of midazolam to an infant and its reversal by flumazenil.
Topics: Anesthesia; Flumazenil; Hematoma, Subdural; Humans; Infant; Male; Midazolam | 1991 |
[Flumazenil and respiratory depression induced by midazolam-fentanyl or midazolam-nalbuphine combinations].
Topics: Adult; Anesthesia, Intravenous; Depression, Chemical; Female; Fentanyl; Flumazenil; Humans; Mastectomy; Midazolam; Nalbuphine; Respiration | 1991 |
The value of flumazenil in the reversal of midazolam-induced sedation for upper gastrointestinal endoscopy.
Topics: Endoscopy, Gastrointestinal; Flumazenil; Humans; Midazolam; Premedication | 1990 |
The rate of CSF formation, resistance to reabsorption of CSF, and aperiodic analysis of the EEG following administration of flumazenil to dogs.
Topics: Anesthesia, Inhalation; Animals; Cerebrospinal Fluid; Cerebrospinal Fluid Pressure; Dogs; Electroencephalography; Flumazenil; Halothane; Midazolam; Nitrous Oxide | 1990 |
Acute dystonia induced by midazolam and abolished by flumazenil.
Topics: Acute Disease; Adolescent; Dystonia; Flumazenil; Humans; Male; Midazolam | 1990 |
Midazolam and flumazenil--the agonist-antagonist concept for sedation and anaesthesia. Proceedings of an international symposium. Sardinia, April 1989.
Topics: Anesthesia; Flumazenil; Humans; Midazolam | 1990 |
Midazolam and flumazenil: the agonist-antagonist concept for sedation and anaesthesia.
Topics: Anesthesia, Intravenous; Cerebrovascular Circulation; Flumazenil; Humans; Intracranial Pressure; Memory; Midazolam | 1990 |
The use of midazolam and flumazenil in cardiovascular diagnostic and therapeutic procedures.
Topics: Cardiovascular Diseases; Coronary Circulation; Female; Flumazenil; Humans; Male; Midazolam; Myocardium | 1990 |
Speed of reversal of midazolam-induced respiratory depression by flumazenil--a study in patients undergoing upper G.I. endoscopy.
Topics: Adult; Aged; Aged, 80 and over; Blood Gas Monitoring, Transcutaneous; Female; Flumazenil; Gastroscopy; Humans; Infusions, Intravenous; Male; Midazolam; Middle Aged; Plethysmography; Respiratory Insufficiency; Time Factors | 1990 |
[Flumazenil and peroperative awakening in surgery of scoliosis].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Child; Female; Fentanyl; Flumazenil; Hemodynamics; Humans; Intraoperative Care; Male; Midazolam; Middle Aged; Paralysis; Scoliosis | 1990 |
Motor performance decrement by midazolam: antagonism by Ro 15-1788 and CGS 8216.
Topics: Animals; Benzodiazepines; Drug Interactions; Flumazenil; Male; Midazolam; Motor Activity; Pyrazoles; Rats | 1990 |
Midazolam and flumazenil in the anaesthetic management of trigeminal nerve thermocoagulation.
Topics: Alfentanil; Blood Pressure; Electrocoagulation; Flicker Fusion; Flumazenil; Heart Rate; Humans; Midazolam; Middle Aged; Time Factors; Trigeminal Nerve; Trigeminal Neuralgia | 1990 |
Effects of benzodiazepine agonist, inverse agonist and antagonist drugs in the mouse staircase test.
Topics: Animals; Anxiety; Behavior, Animal; Carbolines; Flumazenil; Male; Mice; Mice, Inbred ICR; Midazolam; Motor Activity | 1990 |
[Anesthesia with dormicum-aneksat in obstetrical-gynecological operations].
Topics: Adolescent; Adult; Aged; Anesthesia, Endotracheal; Anesthesia, Intravenous; Anesthesia, Obstetrical; Drug Evaluation; Female; Fentanyl; Flumazenil; Humans; Midazolam; Middle Aged; Minor Surgical Procedures; Preanesthetic Medication; Pregnancy | 1990 |
Interaction of midazolam and morphine in the spinal cord of the rat.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electromyography; Flumazenil; Injections, Spinal; Male; Midazolam; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Spinal Cord | 1990 |
On the mechanism by which midazolam causes spinally mediated analgesia.
Topics: Analgesia, Epidural; Animals; Bicuculline; Cyclazocine; Dose-Response Relationship, Drug; Electric Stimulation; Ethylketocyclazocine; Fentanyl; Flumazenil; Male; Midazolam; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds | 1990 |
Profound stress-induced alterations in flurazepam's antiseizure efficacy can be attenuated.
Topics: Animals; Carbolines; Clonazepam; Cold Temperature; Diazepam; Dose-Response Relationship, Drug; Electroshock; Flumazenil; Flurazepam; Male; Mice; Mice, Inbred Strains; Midazolam; Seizures; Stress, Psychological | 1990 |
Subcutaneous flumazenil and recovery from midazolam.
Topics: Anesthesia Recovery Period; Anesthesia, General; Flumazenil; Humans; Midazolam | 1990 |
Fentanyl-midazolam-flumazenil anaesthesia during induced abortion.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Female; Fentanyl; Flumazenil; Humans; Ketamine; Midazolam | 1990 |
[Midazolam and flumazenil in anesthesia for microsurgery of the eye].
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthesia, Local; Female; Flumazenil; Humans; Male; Microsurgery; Midazolam; Middle Aged; Ophthalmologic Surgical Procedures | 1990 |
High-performance liquid chromatographic assay to determine midazolam and flumazenil simultaneously in human plasma.
Topics: Chromatography, High Pressure Liquid; Flumazenil; Humans; Kinetics; Male; Microchemistry; Midazolam | 1990 |
Differential effects of benzodiazepines on cochlear and auditory nerve responses.
Topics: Action Potentials; Animals; Chlordiazepoxide; Cochlear Microphonic Potentials; Evoked Potentials, Auditory; Flumazenil; Guinea Pigs; Midazolam; Pentobarbital; Vestibulocochlear Nerve | 1986 |
'Dental sedation. A review'.
Topics: Anesthesia, Dental; Flumazenil; Humans; Midazolam; Preanesthetic Medication | 1989 |
Cardiovascular responses to flumazenil-induced arousal after arterial surgery.
Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Arousal; Arteries; Arteriosclerosis; Blood Pressure; Flumazenil; Heart Rate; Humans; Midazolam; Middle Aged | 1989 |
Anesthetic interactions of midazolam and fentanyl: is there acute tolerance to the opioid?
Topics: Anesthesia, Inhalation; Animals; Dogs; Drug Interactions; Enflurane; Fentanyl; Flumazenil; Male; Midazolam; Naloxone; Pulmonary Alveoli; Respiration | 1989 |
Use of hospital beds.
Topics: Ambulatory Surgical Procedures; Anesthesia, Local; Flumazenil; Humans; Midazolam | 1989 |
Sedation and reversal of sedation in intensive care.
Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Blood Pressure; Carbon Dioxide; Diazepam; Female; Flumazenil; Heart Rate; Humans; Male; Midazolam; Middle Aged; Postoperative Period; Preanesthetic Medication; Respiration | 1989 |
[Hemodynamic effects of the benzodiazepine antagonist flumazenil following laparotomy under total intravenous anesthesia using midazolam].
Topics: Adult; Anesthesia, Intravenous; Benzodiazepines; Female; Flumazenil; Humans; Laparotomy; Male; Midazolam; Middle Aged | 1989 |
Appetite-modulating drugs in dwarf goats, with special emphasis on benzodiazepine-induced hyperphagia and its antagonism by flumazenil and RO 15-3505.
Topics: Animals; Anti-Anxiety Agents; Appetite Regulation; Azepines; Benzodiazepines; Benzodiazepinones; Body Weight; Diazepam; Female; Flumazenil; Goats; Hyperphagia; Ivermectin; Male; Midazolam; Time Factors | 1989 |
Flumazenil in reversal of the central effects of midazolam used as induction agent in general anesthesia.
Topics: Adult; Anesthesia, General; Female; Flumazenil; Humans; Midazolam; Middle Aged; Resuscitation | 1989 |
Reversal of prolonged sedation using flumazenil in critically ill patients.
Topics: Aged; Critical Care; Female; Flumazenil; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Midazolam; Middle Aged; Prospective Studies; Time Factors | 1989 |
An unusual result with flumazenil.
Topics: Acute Kidney Injury; Critical Care; Female; Flumazenil; Humans; Midazolam; Middle Aged; Nervous System Diseases | 1989 |
[The efficacy of the benzodiazepine antagonist flumazenil (Ro 15-1788) based on the EEG of mechanically ventilated intensive care patients].
Topics: Adult; Aged; Arousal; Benzodiazepines; Coma; Critical Care; Electroencephalography; Flumazenil; Humans; Midazolam; Middle Aged; Pirinitramide; Respiration, Artificial | 1989 |
Midazolam, a short-acting benzodiazepine, resets the circadian clock of the hamster.
Topics: Animals; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Flumazenil; Male; Mesocricetus; Midazolam; Motor Activity; Time Factors | 1989 |
Benzodiazepines acting on ventral surface of medulla cause airway dilation.
Topics: Animals; Atropine; Blood Pressure; Cats; Diazepam; Female; Flumazenil; Lung; Male; Medulla Oblongata; Midazolam; Muscle Relaxation; Muscle, Smooth; Phrenic Nerve; Trachea | 1989 |
Death after flumazenil.
Topics: Aged; Aged, 80 and over; Antidotes; Female; Flumazenil; Humans; Midazolam; Respiratory Insufficiency | 1989 |
[Antagonism of the effects of midazolam by flumazenil on the consumption of oxygen by the body].
Topics: Anesthesia; Flumazenil; Humans; Lorazepam; Midazolam; Oxygen Consumption; Postoperative Period; Preanesthetic Medication | 1989 |
[Respiratory effect of flumazenil after anesthesia with midazolam].
Topics: Adult; Anesthesia; Flumazenil; Humans; Male; Midazolam; Respiration; Respiratory Function Tests; Spirometry | 1989 |
[The antagonism and elimination by midazolam of the blink reflex].
Topics: Blinking; Flumazenil; Humans; Midazolam; Reflex | 1989 |
[The effects of flumazenil given for resuscitation from midazolam anesthesia in patients over 80 years of age].
Topics: Aged; Aged, 80 and over; Anesthesia; Flumazenil; Humans; Midazolam; Postoperative Period | 1989 |
[Comparative study of resuscitation from intravenous anesthesia with the exclusive use of propofol or midazolam and flumazenil].
Topics: Adult; Anesthesia, Intravenous; Drug Combinations; Flumazenil; Humans; Male; Midazolam; Postoperative Period; Propofol | 1989 |
Anaesthesia for diagnostic rigid bronchoscopy: sequential midazolam/flumazenil compared with intermittent thiopentone.
Topics: Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Bronchoscopy; Consciousness; Female; Flumazenil; Humans; Male; Midazolam; Succinylcholine; Thiopental; Time Factors | 1989 |
Benzodiazepines and the mammalian retina. I. Autoradiographic localisation of receptor sites and the lack of effect on the electroretinogram.
Topics: Animals; Benzodiazepines; Body Weight; Cats; Flumazenil; Flunitrazepam; Flurazepam; Membrane Potentials; Midazolam; Photic Stimulation; Rats; Receptors, GABA-A; Retina | 1989 |
Benzodiazepines and the mammalian retina. II. Actions on retinal ganglion cells.
Topics: Action Potentials; Animals; Benzodiazepines; Cats; Female; Flumazenil; Flurazepam; Male; Midazolam; Photic Stimulation; Rats; Receptors, GABA-A; Retina; Retinal Ganglion Cells | 1989 |
The effect of benzodiazepine receptor antagonism by flumazenil on the MAC of halothane in the rat.
Topics: Anesthesia, Inhalation; Animals; Flumazenil; Halothane; Male; Midazolam; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Receptors, GABA-A; Respiration | 1989 |
Discriminative stimulus properties of midazolam in the pigeon.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Buspirone; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Midazolam; Pentobarbital; Pyridazines | 1989 |
Discriminative stimulus properties of midazolam: comparison with other benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Discrimination, Psychological; Flumazenil; Male; Midazolam; Rats; Rats, Inbred Strains | 1989 |
Behavioral differentiation of benzodiazepine ligands after repeated administration in baboons.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Carbolines; Drug Tolerance; Flumazenil; Injections, Intramuscular; Male; Midazolam; Papio; Substance Withdrawal Syndrome | 1989 |
Midazolam antagonizes the analgesic effect of morphine in rats.
Topics: Animals; Flumazenil; Male; Midazolam; Morphine; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds | 1987 |
GABA-benzodiazepine modulation of aversion in the medial hypothalamus of the rat.
Topics: Animals; Avoidance Learning; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Flumazenil; Hypothalamus, Middle; Isoxazoles; Male; Microinjections; Midazolam; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Are the effects of benzodiazepines on discrimination and punishment dissociable?
Topics: Amygdala; Animals; Behavior, Animal; Benzodiazepines; Carbolines; Chlordiazepoxide; Discrimination, Psychological; Ethanolamines; Flumazenil; gamma-Aminobutyric Acid; Midazolam; Punishment; Pyrazoles; Rats; Receptors, GABA-A | 1987 |
Drug interactions and clinical pharmacokinetics of flumazenil.
Topics: Anti-Anxiety Agents; Benzodiazepines; Biological Availability; Drug Interactions; Ethanol; Flumazenil; Flunitrazepam; Half-Life; Humans; Liver; Lorazepam; Midazolam; Receptors, GABA-A; Tomography, Emission-Computed | 1988 |
Proceedings of the International Symposium on the Uses of Midazolam and Flumazenil in Intensive Care. Saint-Paul-de Vence, France, October 16, 1986.
Topics: Critical Care; Flumazenil; Humans; Midazolam; Pain | 1988 |
Midazolam infusion and the benzodiazepine antagonist flumazenil for sedation of intensive care patients.
Topics: Adult; Aged; Critical Care; Flumazenil; Hemodynamics; Humans; Infusions, Intravenous; Midazolam; Middle Aged; Respiration | 1988 |
The effects of a benzodiazepine antagonist Ro 15-1788 in the presence of stable concentrations of midazolam.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Female; Flumazenil; Humans; Hypnotics and Sedatives; Infusions, Parenteral; Injections, Intravenous; Male; Midazolam; Psychomotor Performance; Sleep; Time Factors | 1985 |
Midazolam cue in rats: generalization tests with anxiolytic and other drugs.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Cues; Dose-Response Relationship, Drug; Flumazenil; Generalization, Stimulus; Male; Midazolam; Pentobarbital; Rats | 1985 |
Effects of two benzodiazepines and a benzodiazepine antagonist on neuromuscular blockade in the anaesthetized cat.
Topics: Animals; Blood Pressure; Cats; Diazepam; Drug Interactions; Drug Synergism; Female; Flumazenil; Male; Midazolam; Neuromuscular Blocking Agents; Neuromuscular Junction; Pancuronium; Sciatic Nerve; Vecuronium Bromide | 1987 |
Evidence for control of cardiac vagal tone by benzodiazepine receptors.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Atropine; Chlordiazepoxide; Flumazenil; Heart; Heart Rate; Male; Midazolam; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vagus Nerve | 1987 |
Effects of an intrathecally administered benzodiazepine receptor agonist, antagonist and inverse agonist on morphine-induced inhibition of a spinal nociceptive reflex.
Topics: Animals; Anti-Anxiety Agents; Azepines; Flumazenil; Injections, Spinal; Male; Midazolam; Morphine; Nociceptors; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A | 1988 |
Midazolam antagonism.
Topics: Aged; Drug Combinations; Flumazenil; Gastroscopy; Humans; Midazolam | 1988 |
Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.
Topics: Animals; Azabicyclo Compounds; Barbital; Benzodiazepines; Benzodiazepinones; Buspirone; Caffeine; Chlordiazepoxide; Cinanserin; Clozapine; Conditioning, Operant; Cyproheptadine; Diazepam; Diphenhydramine; Discrimination Learning; Electroshock; Flumazenil; Male; Midazolam; Muscimol; Nordazepam; Pentobarbital; Piperazines; Pyridazines; Pyrimidines; Saimiri; Tripelennamine | 1985 |
Behavioral effects and benzodiazepine antagonist activity of Ro 15-1788 (flumazepil) in pigeons.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Columbidae; Conditioning, Psychological; Dose-Response Relationship, Drug; Flumazenil; Male; Midazolam; Punishment | 1985 |
Discriminative and aversive stimulus effects of beta-carboline ethyl ester in rhesus monkeys.
Topics: Animals; Avoidance Learning; Benzodiazepines; Benzodiazepinones; Carbolines; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Macaca mulatta; Methohexital; Midazolam | 1986 |
Evidence that the anticonflict effect of midazolam in amygdala is mediated by the specific benzodiazepine receptors.
Topics: Amygdala; Animals; Benzodiazepines; Benzodiazepinones; Carbolines; Conflict, Psychological; Flumazenil; Male; Midazolam; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Benzodiazepine receptor ligands and the consumption of a highly palatable diet in non-deprived male rats.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Carbolines; Drug Interactions; Feeding Behavior; Flumazenil; Ligands; Male; Midazolam; Pyrazoles; Rats; Receptors, GABA-A | 1985 |
Discriminative and aversive properties of beta-carboline-3-carboxylic acid ethyl ester, a benzodiazepine receptor inverse agonist, in rhesus monkeys.
Topics: Animals; Avoidance Learning; Benzodiazepines; Benzodiazepinones; Carbolines; Discrimination Learning; Flumazenil; Histamine; Macaca mulatta; Methohexital; Midazolam; Receptors, GABA-A | 1986 |
Effects of the benzodiazepine receptor ligands midazolam, Ro 15-1788, and Ro 5-4864, alone and in combinations, on platelet serotonin uptake.
Topics: Benzodiazepines; Benzodiazepinones; Blood Platelets; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Humans; In Vitro Techniques; Kinetics; Midazolam; Receptors, GABA-A; Serotonin | 1986 |
Benzodiazepine receptor involvement in the control of receptive field size and responsiveness in primary somatosensory cortex.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Cats; Diazepam; Female; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; Male; Midazolam; Neurons; Receptors, GABA-A; Sensory Thresholds; Somatosensory Cortex; Touch | 1986 |
Midazolam cue in rats: effects of Ro 15-1788 and picrotoxin.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Male; Midazolam; Nicotine; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A | 1986 |
Discriminative stimulus effects of a nicotine-midazolam mixture in rats.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Male; Mecamylamine; Midazolam; Nicotine; Rats | 1987 |
Intrathecal midazolam in the rat: evidence for spinally-mediated analgesia.
Topics: Action Potentials; Analgesia; Animals; Flumazenil; Injections, Spinal; Male; Midazolam; Pain Measurement; Ranidae; Rats; Rats, Inbred Strains; Sciatic Nerve; Sensory Thresholds; Spinal Cord | 1987 |
Cerebral effects of high-dose midazolam and subsequent reversal with Ro 15-1788 in dogs.
Topics: Animals; Brain; Cerebrovascular Circulation; Dogs; Drug Combinations; Electrocardiography; Flumazenil; Midazolam; Nitrous Oxide; Oxygen Consumption | 1988 |
[Use of flumazenil (RO 15-1788) after prolonged infusion of midazolam in anesthesia for intracranial surgery].
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Brain Diseases; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Postoperative Period; Time Factors | 1988 |
RO 15-1788 produces naloxone-reversible analgesia in the rat.
Topics: Analgesics; Animals; Flumazenil; Injections, Intraperitoneal; Injections, Intraventricular; Male; Midazolam; Naloxone; Pain; Rats | 1988 |
The effects of midazolam reversal by RO 15-1788 on cerebral perfusion pressure in patients with severe head injury.
Topics: Adult; Cerebrovascular Circulation; Coma; Craniocerebral Trauma; Female; Flumazenil; Humans; Intracranial Pressure; Male; Midazolam; Middle Aged; Monitoring, Physiologic | 1988 |
Reversal of sedation by prolonged infusion of flumazenil (Anexate, Ro 15-1788).
Topics: Adult; Flumazenil; Humans; Infusions, Intravenous; Male; Midazolam; Time Factors | 1988 |
Midazolam and discriminative motor control: chronic administration, withdrawal and modulation by the antagonist Ro 15-1788.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Male; Midazolam; Motor Activity; Rats; Substance Withdrawal Syndrome | 1988 |
The reversal of midazolam sedation with the benzodiazepine antagonist flumazenil (Anexate).
Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Benzodiazepines; Drug Evaluation; Drug Interactions; Endoscopy; Flumazenil; Humans; Midazolam | 1988 |
The effects of flumazenil, a new benzodiazepine antagonist, on the reversal of midazolam sedation and amnesia in dental patients.
Topics: Adolescent; Adult; Anesthesia, Dental; Double-Blind Method; Female; Flumazenil; Humans; Male; Memory; Mental Recall; Midazolam; Middle Aged; Placebos; Preanesthetic Medication; Tooth Extraction | 1988 |
Benzodiazepine receptors in the periaqueductal grey mediate anti-aversive drug action.
Topics: Animals; Avoidance Learning; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Electric Stimulation; Electrodes, Implanted; Escape Reaction; Flumazenil; Male; Midazolam; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reinforcement, Psychology | 1984 |
Agonistic action of a benzodiazepine antagonist: effects of Ro 15-1788 and midazolam on hypertonic NaCl intake.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Drinking Behavior; Flumazenil; Kinetics; Male; Midazolam; Osmolar Concentration; Rats; Sodium Chloride | 1983 |
Differential effects of the benzodiazepine antagonist Ro 15-1788 after "general anaesthetic" doses of benzodiazepines in mice.
Topics: Anesthesia, General; Anesthetics; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Convulsants; Diazepam; Flumazenil; Flurazepam; Male; Mice; Mice, Inbred Strains; Midazolam; Reflex | 1984 |
Actions of midazolam in the spinal cord of the cat.
Topics: Afferent Pathways; Animals; Benzodiazepines; Benzodiazepinones; Cats; Flumazenil; gamma-Aminobutyric Acid; Interneurons; Midazolam; Norepinephrine; Reflex; Spinal Cord | 1983 |
Antagonism of the effects of midazolam on phrenic nerve activity in the dog by Ro 15-1788 and Ro 15-3505.
Topics: Action Potentials; Anesthetics; Animals; Benzodiazepines; Benzodiazepinones; Blood Pressure; Dogs; Flumazenil; Midazolam; Phrenic Nerve; Time Factors | 1984 |
Midazolam-induced increase in NaCl solution ingestion: differential effect of the benzodiazepine antagonists Ro 15-1788 and CGS 8216.
Topics: Animals; Appetite; Benzodiazepines; Benzodiazepinones; Drug Interactions; Flumazenil; Male; Midazolam; Pyrazoles; Rats; Sodium Chloride | 1984 |
Specific benzodiazepine antagonist RO15-1788 and thirst-induced drinking in the rat.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Drinking Behavior; Drug Antagonism; Flumazenil; Male; Midazolam; Rats; Water Deprivation | 1982 |
Differences in midazolam-induced breathing patterns in healthy volunteers.
Topics: Abdominal Muscles; Adult; Body Height; Body Weight; Conscious Sedation; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam; Oxygen; Reference Values; Respiration; Sex Factors; Snoring; Thorax; Unconsciousness | 1995 |
Effects of midazolam on intracellular Ca2+ and tension in airway smooth muscles.
Topics: Animals; Anti-Anxiety Agents; Calcium; Drug Interactions; Flumazenil; Fluorometry; GABA Modulators; In Vitro Techniques; Intracellular Fluid; Ion Transport; Isoquinolines; Midazolam; Muscle Contraction; Muscle, Smooth; Potassium; Swine; Trachea | 1995 |
[Effects of midazolam on respiratory drive in healthy volunteers].
Topics: Adjuvants, Anesthesia; Adult; Airway Resistance; Electromyography; Flumazenil; Humans; Intercostal Muscles; Lung Volume Measurements; Male; Midazolam; Respiration; Respiratory Center | 1995 |
Anaesthesia for thyroplasty.
Topics: Anesthesia; Flumazenil; Humans; Larynx; Midazolam; Vocal Cord Paralysis | 1995 |
Stereospecific transduction of behavioral effects via diazepam-insensitive GABAA receptors.
Topics: Animals; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Columbidae; Diazepam; Discrimination Learning; Flumazenil; GABA Modulators; Imidazoles; Male; Midazolam; Oxadiazoles; Radioligand Assay; Receptors, GABA-A; Sensitivity and Specificity; Stereoisomerism | 1995 |
Prolonged sedation due to accumulation of conjugated metabolites of midazolam.
Topics: Aged; Aged, 80 and over; Animals; Coma; Electroencephalography; Female; Flumazenil; Glucuronates; Humans; Liver Function Tests; Male; Midazolam; Middle Aged; Prospective Studies; Rats; Receptors, GABA-A; Renal Insufficiency | 1995 |
[Sedation for diagnostic and therapeutic procedures in interventional radiology].
Topics: Conscious Sedation; Flumazenil; Humans; Hypnotics and Sedatives; Midazolam; Radiology, Interventional | 1995 |
[Use of midazolam in the patient with cardiac, neurologic or respiratory disease and the aged].
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics; Cardiac Surgical Procedures; Conscious Sedation; Flumazenil; Heart Diseases; Humans; Hypnotics and Sedatives; Lung Diseases, Obstructive; Midazolam; Neurosurgery | 1995 |
[Use of midazolam in neurosurgery].
Topics: Anesthesia, General; Anesthetics; Central Nervous System; Craniotomy; Flumazenil; Humans; Midazolam; Neurosurgery | 1995 |
Equivalent dipoles of FFT data visualize drug interaction at benzodiazepine receptors.
Topics: Adult; Attention; Brain; Electroencephalography; Electrophysiology; Female; Flumazenil; GABA-A Receptor Antagonists; Humans; Male; Midazolam; Receptors, GABA-A | 1993 |
Stress-induced changes in respiratory quotient, energy expenditure and locomotor activity in rats: effects of midazolam.
Topics: Animals; Carbon Dioxide; Conditioning, Operant; Electroshock; Energy Metabolism; Flumazenil; Male; Midazolam; Motor Activity; Oxygen Consumption; Photic Stimulation; Rats; Rats, Wistar; Reinforcement, Psychology; Respiratory Mechanics; Stress, Psychological | 1994 |
Defeat engenders pentylenetetrazole-appropriate responding in rats: antagonism by midazolam.
Topics: Agonistic Behavior; Animals; Anxiety; Conditioning, Operant; Discrimination, Psychological; Flumazenil; Generalization, Stimulus; Male; Midazolam; Pentylenetetrazole; Rats; Reinforcement Schedule; Social Behavior | 1994 |
Mechanisms of the influence of midazolam on morphine antinociception at spinal and supraspinal levels in rats.
Topics: Analgesia; Animals; Drug Interactions; Flumazenil; Injections, Intraventricular; Male; Midazolam; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Reaction Time; Spinal Cord | 1994 |
Flumazenil to reverse midazolam sedation.
Topics: Bronchoscopy; Conscious Sedation; Fiber Optic Technology; Flumazenil; Humans; Midazolam | 1995 |
The central and basolateral amygdala differentially mediate the anxiolytic effects of benzodiazepines.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Flumazenil; Injections; Male; Midazolam; Rats; Rats, Sprague-Dawley | 1995 |
Simultaneous determination of midazolam and flumazenil concentrations in human plasma by gas chromatography.
Topics: Chromatography, Gas; Flumazenil; Humans; Midazolam; Reproducibility of Results | 1995 |
Intravenous midazolam suppresses noxiously evoked activity of spinal wide dynamic range neurons in cats.
Topics: Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Evoked Potentials; Female; Flumazenil; Heart Rate; Infusions, Intravenous; Male; Midazolam; Neurons; Spinal Cord | 1995 |
Drug discrimination analysis of midazolam under a three-lever procedure: I. Dose-dependent differences in generalization and antagonism.
Topics: Animals; Caffeine; Cocaine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Male; Methocarbamol; Midazolam; Morphine; Pentobarbital; Rats; Rats, Sprague-Dawley | 1995 |
Walk-in, walk-out day case genito-scrotal surgery with sedation reversal. A survey of patient attitudes and morbidity.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, General; Attitude to Health; Conscious Sedation; Flumazenil; Follow-Up Studies; Genitalia, Male; Humans; Male; Midazolam; Middle Aged; Morbidity; Pain, Postoperative; Patient Satisfaction; Surveys and Questionnaires | 1994 |
Effects of midazolam and naloxone in rats tested for sensitivity/reactivity to formalin pain in a familiar, novel or aversively conditioned environment.
Topics: Analgesia; Animals; Conditioning, Operant; Conditioning, Psychological; Environment; Extinction, Psychological; Flumazenil; Formaldehyde; Male; Midazolam; Naloxone; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Reinforcement, Psychology | 1994 |
Role of benzodiazepine receptors located in the dorsal periaqueductal grey of rats in anxiety.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Anxiety; Appetite Depressants; Carbolines; Diazepam; Dose-Response Relationship, Drug; Exploratory Behavior; Flumazenil; Male; Microinjections; Midazolam; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, GABA-A | 1993 |
Low and high doses of midazolam differentially affect hypoalgesia in rats conditioned to a heat stressor.
Topics: Analgesia; Animals; Behavior, Animal; Conditioning, Psychological; Dose-Response Relationship, Drug; Fear; Flumazenil; Hot Temperature; Male; Midazolam; Naloxone; Pain Measurement; Rats; Rats, Wistar; Stress, Psychological | 1993 |
The article on midazolam.
Topics: Conscious Sedation; Flumazenil; Humans; Midazolam | 1994 |
Antagonistic effects of atipamezole and flumazenil on medetomidine-midazolam induced sedation in laboratory pigs.
Topics: Adrenergic alpha-Antagonists; Animals; Animals, Laboratory; Arousal; Body Temperature; Castration; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Heart Rate; Hypnotics and Sedatives; Imidazoles; Medetomidine; Midazolam; Swine; Time Factors | 1993 |
Flumazenil reversal of benzodiazepine-induced sedation for a patient with severe pre-ECT anxiety.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Electroconvulsive Therapy; Flumazenil; Humans; Lorazepam; Male; Midazolam; Schizophrenia | 1994 |
Effects of midazolam and flumazenil on carotid sinus baroreflex control of circulation in rabbits.
Topics: Animals; Baroreflex; Blood Pressure; Carotid Arteries; Carotid Sinus; Depression, Chemical; Flumazenil; Heart Rate; Hemodynamics; Midazolam; Rabbits | 1994 |
Opposite effects of midazolam and beta-carboline-3-carboxylate ethyl ester on the release of dopamine from rat nucleus accumbens measured by in vivo microdialysis.
Topics: Adenosine; Animals; Carbolines; Dopamine; Dose-Response Relationship, Drug; Flumazenil; Ligands; Male; Microdialysis; Midazolam; Nucleus Accumbens; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrodotoxin; Theobromine; Xanthines | 1994 |
[The use of midazolam and flumazenil for short-term anesthesia in terminating an early pregnancy].
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Drug Evaluation; Female; Flumazenil; Humans; Midazolam; Pregnancy; Pregnancy Trimester, First; Time Factors | 1993 |
[Flumazenil antagonism of midazolam-induced respiratory depression].
Topics: Adult; Depression, Chemical; Flumazenil; Humans; Male; Midazolam; Respiration | 1994 |
Reversal of midazolam sedation with rectal flumazenil in children.
Topics: Administration, Rectal; Child; Child, Preschool; Flumazenil; Humans; Infant; Midazolam; Time Factors | 1994 |
Midazolam and flumazenil pharmacokinetics and pharmacodynamics following simultaneous administration to human volunteers.
Topics: Adult; Anxiety; Awareness; Flicker Fusion; Flumazenil; Half-Life; Humans; Male; Midazolam; Protein Binding; Psychomotor Performance; Receptors, GABA-A; Sleep Stages | 1994 |
Flumazenil as a diagnostic tool in the differential diagnosis of coma in a critically ill patient.
Topics: Aged; Bacterial Infections; Coma; Critical Illness; Diagnosis, Differential; Diazepam; Flumazenil; Hepatic Encephalopathy; Humans; Lorazepam; Male; Midazolam | 1994 |
Temporary abolition of seizure activity by flumazenil in a case of valproate-induced non-convulsive status epilepticus.
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Electroencephalography; Evoked Potentials; Female; Flumazenil; Humans; Midazolam; Phenobarbital; Seizures; Status Epilepticus; Valproic Acid | 1993 |
The septum and amygdala differentially mediate the anxiolytic effects of benzodiazepines.
Topics: Amygdala; Animals; Anxiety; Avoidance Learning; Brain; Flumazenil; Infusions, Parenteral; Learning; Male; Midazolam; Organ Specificity; Rats; Rats, Sprague-Dawley | 1994 |
Midazolam-opioid combination and postoperative upper airway obstruction in children.
Topics: Adenoidectomy; Airway Obstruction; Anesthesia, Intravenous; Child; Flumazenil; Humans; Male; Midazolam; Morphine; Positive-Pressure Respiration; Postoperative Complications; Preanesthetic Medication; Tonsillectomy | 1994 |
Effects of flumazenil during administration of midazolam on pial vessel diameter and regional cerebral blood flow in cats.
Topics: Animals; Arterioles; Blood Pressure; Carbon Dioxide; Cats; Cerebrovascular Circulation; Craniotomy; Flumazenil; Hydrogen-Ion Concentration; Laser-Doppler Flowmetry; Midazolam; Pia Mater; Vasodilation; Venules | 1993 |
Simultaneous determination of flumazenil, midazolam and metabolites in human biological fluids by liquid chromatography.
Topics: Child; Chromatography, High Pressure Liquid; Flumazenil; Humans; Indicators and Reagents; Midazolam; Spectrophotometry, Ultraviolet | 1993 |
[Flumazenil, a benzodiazepine antagonist, in endoscopic premedication].
Topics: Adult; Aged; Dose-Response Relationship, Drug; Endoscopy, Gastrointestinal; Female; Flumazenil; Humans; Male; Midazolam; Middle Aged; Premedication | 1993 |
Tolerance to the behavioral effects of chlordiazepoxide: pharmacological and biochemical selectivity.
Topics: Amphetamine; Animals; Behavior, Animal; Caffeine; Carbolines; Chlordiazepoxide; Chlorides; Chlorine; Dose-Response Relationship, Drug; Drug Tolerance; Flumazenil; gamma-Aminobutyric Acid; Male; Midazolam; Morphine; Pentobarbital; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sensitivity and Specificity; Stimulation, Chemical | 1993 |
Effects of midazolam and flumazenil on ventilation during sustained hypoxia in humans.
Topics: Adult; Analysis of Variance; Brain Stem; Flumazenil; gamma-Aminobutyric Acid; Humans; Hypoxia; Infusions, Intravenous; Male; Midazolam; Pulmonary Gas Exchange; Respiration; Time Factors | 1993 |
Benzodiazepine receptor equilibrium constants for flumazenil and midazolam determined in humans with the single photon emission computer tomography tracer [123I]iomazenil.
Topics: Adolescent; Adult; Binding Sites; Blood Proteins; Chromatography, High Pressure Liquid; Flumazenil; Humans; Male; Midazolam; Protein Binding; Receptors, GABA-A | 1993 |
Does flumazenil antagonize midazolam-induced depression of ventilatory response to hypoxia?
Topics: Depression, Chemical; Flumazenil; Humans; Hypoxia; Midazolam; Respiration, Artificial | 1994 |
Antagonism by flumazenil of midazolam-induced changes in quantitative electroencephalographic data from isoflurane-anesthetized dogs.
Topics: Anesthesia, General; Animals; Blood Pressure; Body Temperature; Dogs; Electroencephalography; Female; Flumazenil; Heart Rate; Isoflurane; Midazolam | 1993 |
Direct spinal effect of intrathecal and extradural midazolam on visceral noxious stimulation in rabbits.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; Injections, Epidural; Injections, Intramuscular; Injections, Spinal; Midazolam; Motor Neurons; Rabbits; Reflex; Sensory Thresholds; Spinal Cord; Viscera | 1993 |
Can flumazenil antagonize cardiac responses induced by midazolam.
Topics: Animals; Flumazenil; Heart; In Vitro Techniques; Midazolam; Rabbits | 1993 |
Reversal of midazolam sedation.
Topics: Akathisia, Drug-Induced; Conscious Sedation; Critical Care; Flumazenil; Humans; Midazolam; Substance Withdrawal Syndrome | 1993 |
Inhibition of hippocampal acetylcholine release by benzodiazepines: antagonism by flumazenil.
Topics: Acetylcholine; Analysis of Variance; Animals; Diazepam; Drug Interactions; Flumazenil; Hippocampus; Male; Midazolam; Rats; Rats, Sprague-Dawley | 1993 |
Effect of midazolam infusion and flumazenil administration on epinephrine arrhythmogenicity in dogs anesthetized with halothane.
Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Dogs; Epinephrine; Female; Flumazenil; Halothane; Hemodynamics; Infusions, Intravenous; Male; Midazolam; Time Factors | 1993 |
Effects of midazolam and flunitrazepam on the release of dopamine from rat striatum measured by in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dialysis; Dopamine; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; Homovanillic Acid; Male; Midazolam; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1993 |
Pharmacokinetics of flumazenil and midazolam.
Topics: Child; Child, Preschool; Circumcision, Male; Flumazenil; Half-Life; Humans; Male; Midazolam; Psychomotor Performance; Time Factors | 1993 |
Attenuation of midazolam-induced EEG activation in rats by both flumazenil and hyperbaric oxygen.
Topics: Anesthetics, Intravenous; Animals; Electroencephalography; Evoked Potentials, Somatosensory; Flumazenil; GABA Modulators; Hyperbaric Oxygenation; Hyperoxia; Midazolam; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
Behavioral and biochemical characterization of benzodiazepine receptor partial agonists in pigeons.
Topics: Animals; Anti-Anxiety Agents; Columbidae; Discrimination Learning; Flumazenil; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Male; Midazolam; Punishment | 1996 |
Rectal flumazenil to reverse midazolam sedation in children.
Topics: Administration, Rectal; Antidotes; Child; Child, Preschool; Flumazenil; Humans; Hypnotics and Sedatives; Infant; Midazolam | 1996 |
Periodic cardiovascular and ventilatory activity during midazolam sedation.
Topics: Adult; Blood Pressure; Conscious Sedation; Flumazenil; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Photoplethysmography; Respiration; Stimulation, Chemical | 1996 |
Reversal of a paradoxical reaction to midazolam with flumazenil.
Topics: Adult; Akathisia, Drug-Induced; Anesthetics, Intravenous; Antidotes; Flumazenil; GABA Modulators; Humans; Male; Midazolam | 1996 |
Semilinear canonical correlation applied to the measurement of the electroencephalographic effects of midazolam and flumazenil reversal.
Topics: Adult; Anti-Anxiety Agents; Electroencephalography; Flumazenil; Humans; Midazolam; Statistics as Topic | 1996 |
[Acute overdose of Zolpidem (Stilnox)].
Topics: Adolescent; Adult; Aged; Antidotes; Coma; Drug Overdose; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Pyridines; Retrospective Studies; Triazolam; Zolpidem | 1996 |
Flumazenil reverses paradoxical reaction to midazolam in a child.
Topics: Antidotes; Child; Flumazenil; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Midazolam | 1996 |
Effect of midazolam with and without flumazenil on conditioned hypoalgesia.
Topics: Animals; Conditioning, Psychological; Drug Combinations; Flumazenil; Learning; Male; Midazolam; Pain Measurement; Rats; Rats, Wistar; Reaction Time | 1996 |
Increased food intake following injection of the benzodiazepine receptor agonist midazolam into the IVth ventricle.
Topics: Animals; Anti-Anxiety Agents; Cerebral Ventricles; Dose-Response Relationship, Drug; Eating; Flumazenil; GABA Modulators; Hyperphagia; Injections, Intraventricular; Male; Microinjections; Midazolam; Rats; Stimulation, Chemical | 1996 |
Hyperphagia induced by direct administration of midazolam into the parabrachial nucleus of the rat.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Cerebral Ventricles; Feeding Behavior; Flumazenil; GABA Modulators; Hyperphagia; Injections, Intraventricular; Male; Midazolam; Motor Activity; Pons; Rats; Sucrose | 1996 |
Synergistic interactions between midazolam and alfentanil in isolated neonatal rat spinal cord.
Topics: Alfentanil; Analgesics, Opioid; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Flumazenil; Hypnotics and Sedatives; Midazolam; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord | 1996 |
The neuroanatomical specificity of the anxiolytic effects of intra-septal infusions of midazolam.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Exploratory Behavior; Flumazenil; GABA Modulators; Injections; Male; Maze Learning; Midazolam; Rats; Rats, Sprague-Dawley; Septum Pellucidum | 1996 |
Blockade of behavioral effects of bretazenil by flumazenil and ZK 93,426 in pigeons.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Carbolines; Columbidae; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; GABA Antagonists; GABA Modulators; Male; Midazolam; Punishment; Receptors, GABA | 1997 |
A five minute experience in the elevated plus-maze alters the state of the benzodiazepine receptor in the dorsal raphe nucleus.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Interpersonal Relations; Male; Maze Learning; Midazolam; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1997 |
Antagonism of AND and AND-OR drug mixture discriminations in rats.
Topics: Animals; Anti-Anxiety Agents; Association Learning; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Flumazenil; GABA Modulators; Mecamylamine; Midazolam; Motivation; Nicotine; Nicotinic Antagonists; Rats; Reinforcement Schedule; Substance-Related Disorders | 1997 |
The role of midazolam-induced sedation in bone marrow aspiration/trephine biopsies.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Antidotes; Awareness; Bone Marrow; Conscious Sedation; Contraindications; Female; Flumazenil; Headache; Humans; Hypertension; Hypnotics and Sedatives; Hypotension; Male; Midazolam; Middle Aged; Nausea; Pain; Respiratory Insufficiency; Seizures; Sleep Stages; Trephining | 1996 |
Midazolam-induced rapid changes in licking behaviour: evidence for involvement of endogenous opioid peptides.
Topics: Animals; Drug Interactions; Feeding Behavior; Flumazenil; Male; Midazolam; Naloxone; Opioid Peptides; Rats | 1997 |
Does midazolam cause retrograde amnesia, and can flumazenil reverse that amnesia?
Topics: Amnesia, Retrograde; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Benzodiazepines; Flumazenil; GABA Modulators; Humans; Male; Midazolam; Middle Aged | 1997 |
Non-GABAergic effects of midazolam, diazepam and flumazenil on voltage-dependent ion currents in NG108-15 cells.
Topics: Animals; Calcium Channels; Diazepam; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Glioma; Hybrid Cells; Ion Channels; Membrane Potentials; Midazolam; Neuroblastoma; Patch-Clamp Techniques; Potassium Channels; Receptors, GABA-A; Sodium Channels | 1997 |
Mechanism of the negative inotropic effect of midazolam and diazepam in cultured foetal mouse cardiac myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Anxiety Agents; Calcium; Calcium Channel Agonists; Cells, Cultured; Depression, Chemical; Diazepam; Female; Fetal Heart; Flumazenil; GABA-A Receptor Antagonists; Heart Rate, Fetal; Hypnotics and Sedatives; Mice; Mice, Inbred ICR; Midazolam; Pregnancy; Ryanodine; Sarcoplasmic Reticulum | 1997 |
The direct effects of diazepam and midazolam on myocardial depression in cultured rat ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Anxiety Agents; Cells, Cultured; Depression, Chemical; Diazepam; Flumazenil; Heart; Heart Rate; Midazolam; Rats | 1997 |
Effects of midazolam on glycemia and serum lipids in rats.
Topics: Aminophylline; Animals; Anti-Anxiety Agents; Blood Glucose; Drug Interactions; Fenofibrate; Flumazenil; GABA Modulators; Hypolipidemic Agents; Isoquinolines; Lipids; Male; Midazolam; Phosphodiesterase Inhibitors; Rats; Rats, Wistar | 1996 |
A significant difference is one that makes a difference.
Topics: Anesthetics, Intravenous; Antidotes; Benzodiazepines; Clinical Trials as Topic; Conscious Sedation; Emergency Medicine; Emergency Service, Hospital; Flumazenil; Humans; Midazolam; Pain; Practice Guidelines as Topic; United States | 1997 |
Midazolam reverses histamine-induced bronchoconstriction in dogs.
Topics: Anesthetics, Intravenous; Animals; Bronchi; Bronchoconstriction; Bronchoscopy; Dogs; Epinephrine; Flumazenil; GABA Modulators; Histamine; Histamine Antagonists; Midazolam | 1997 |
Comparison of routes of flumazenil administration to reverse midazolam-induced respiratory depression in a canine model.
Topics: Administration, Rectal; Administration, Sublingual; Animals; Antidotes; Cross-Over Studies; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Flumazenil; Hypnotics and Sedatives; Injections, Intramuscular; Injections, Intravenous; Midazolam; Random Allocation; Respiratory Insufficiency; Time Factors | 1997 |
Paradoxical reactions in children associated with midazolam use during endoscopy.
Topics: Adjuvants, Anesthesia; Adolescent; Adolescent Behavior; Aggression; Akathisia, Drug-Induced; Anti-Anxiety Agents; Antidotes; Child; Child Behavior; Child, Preschool; Crying; Drug Monitoring; Endoscopy; Female; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Infant; Infant Behavior; Male; Meperidine; Midazolam; Orientation; Psychomotor Agitation; Tachycardia; Time Factors | 1997 |
Use of inhalational and intravenous sedation in dentistry.
Topics: Accidents; Anesthesia, Dental; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Anxiety Agents; Antidotes; Cause of Death; Computers; Conscious Sedation; Dental Care; Diazepam; Drug Overdose; Emergencies; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Iatrogenic Disease; Infusion Pumps; Isoflurane; Midazolam; Nitrous Oxide; Oxygen; Practice Guidelines as Topic; Propofol; United Kingdom | 1997 |
Timing and side effects of flumazenil for dental outpatients receiving intravenous sedation with midazolam.
Topics: Adult; Ambulatory Care; Anesthesia, Dental; Anti-Anxiety Agents; Conscious Sedation; Drug Evaluation; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Injections, Intravenous; Male; Midazolam; Middle Aged; Pilot Projects; Time Factors | 1997 |
Stable low-rate midazolam self-injection with concurrent physical dependence under conditions of long-term continuous availability in baboons.
Topics: Animals; Anti-Anxiety Agents; Feeding Behavior; Flumazenil; Male; Midazolam; Papio; Self Administration; Substance Withdrawal Syndrome; Substance-Related Disorders | 1998 |
Opisthotonos after flumazenil administered to antagonize midazolam previously administered to treat developing local anesthetic toxicity.
Topics: Adolescent; Flumazenil; Humans; Male; Midazolam; Seizures | 1998 |
Studies on benzodiazepines and opioids administered alone and in combination in rhesus monkeys: ventilation and drug discrimination.
Topics: Animals; Benzodiazepines; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Female; Flumazenil; Macaca mulatta; Male; Midazolam; Morphine; Naltrexone; Narcotics; Respiration | 1998 |
Oral midazolam: pediatric conscious sedation.
Topics: Administration, Oral; Anesthesia, Dental; Child; Child, Preschool; Conscious Sedation; Dental Anxiety; Dental Care for Children; Diazepam; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Midazolam | 1998 |
[Risk of confusion in Hypnovel and Anexate packaging (Roche)].
Topics: Drug Packaging; Equipment Safety; Flumazenil; Midazolam | 1997 |
[Effects of anesthetics on somatosensory evoked potentials by median nerve stimulation in human--analyses after single administration in volunteers].
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Electric Stimulation; Evoked Potentials, Somatosensory; Flumazenil; Humans; Male; Median Nerve; Midazolam; Naloxone; Nitrous Oxide; Propofol; Reaction Time; Thiopental | 1998 |
GABA receptors and benzodiazepine binding sites modulate hippocampal acetylcholine release in vivo.
Topics: Acetylcholine; Animals; Benzodiazepines; Binding Sites; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Hippocampus; Ligands; Male; Midazolam; Rats; Rats, Wistar; Receptors, GABA; Septum Pellucidum | 1998 |
Stimulation of benzodiazepine receptors in the dorsal hippocampus and median raphé reveals differential GABAergic control in two animal tests of anxiety.
Topics: Animals; Anxiety; Behavior, Animal; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Male; Maze Learning; Microinjections; Midazolam; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, GABA-A; Social Behavior | 1998 |
Inhibitory effects of diazepam and midazolam on Ca2+ and K+ channels in canine tracheal smooth muscle cells.
Topics: Anesthetics, Intravenous; Animals; Calcium Channel Blockers; Calcium Channels; Diazepam; Dogs; Electrophysiology; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Isoquinolines; Midazolam; Muscle, Smooth; Patch-Clamp Techniques; Potassium Channel Blockers; Trachea | 1999 |
[The effect of midazolam on the memory during cesarean section and the modulation by flumazenil].
Topics: Adult; Amnesia, Retrograde; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthesia, Spinal; Anti-Anxiety Agents; Cesarean Section; Female; Flumazenil; Humans; Memory; Midazolam; Nitrous Oxide; Pregnancy | 1999 |
Midazolams cardiac depressant effects and their lack of reversal by flumazenil in isolated rabbit hearts.
Topics: Anesthetics, Intravenous; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; GABA Modulators; Heart; Heart Rate; In Vitro Techniques; Male; Midazolam; Rabbits; Ventricular Function, Left; Ventricular Pressure | 1999 |
Midazolam effects on prepulse inhibition of the acoustic blink reflex.
Topics: Acoustic Stimulation; Adult; Anti-Anxiety Agents; Blinking; Dose-Response Relationship, Drug; Electromyography; Flumazenil; Humans; Male; Midazolam; Reflex, Startle | 1999 |
Midazolam-induced hyperalgesia in rats: modulation via GABA(A) receptors at supraspinal level.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Central Nervous System Depressants; Dose-Response Relationship, Drug; Drug Combinations; Ethanol; Flumazenil; GABA Antagonists; GABA Modulators; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Midazolam; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1999 |
Apparent pA2 values of benzodiazepine antagonists and partial agonists in monkeys.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Carbolines; Dose-Response Relationship, Drug; Electroshock; Feeding Behavior; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Kinetics; Male; Midazolam; Receptors, GABA-A; Reinforcement Schedule; Saimiri | 1999 |
[Persisting respiratory depression following intrathecal administration of morphine and simultaneous sedation with midazolam].
Topics: Aged; Analgesics, Opioid; Flumazenil; Humans; Hypnotics and Sedatives; Injections, Spinal; Intubation, Intratracheal; Male; Midazolam; Morphine; Naloxone; Narcotic Antagonists; Respiration, Artificial; Respiratory Insufficiency | 1999 |
Discriminative stimulus effects of zolpidem in squirrel monkeys: comparison with conventional benzodiazepines and sedative-hypnotics.
Topics: Animals; Benzodiazepines; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Hypnotics and Sedatives; Male; Midazolam; Pyridines; Saimiri; Zolpidem | 1999 |
Baclofen and midazolam alter c-fos induction by peripheral noxious or innocuous stimulation in the spinal cord of normal and monoarthritic rats.
Topics: Animals; Arthritis, Experimental; Baclofen; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Genes, fos; Male; Midazolam; Organophosphorus Compounds; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Stimulation, Chemical | 1999 |
Conscious sedation: is there a need for improvement?
Topics: Conscious Sedation; Costs and Cost Analysis; Endoscopy, Gastrointestinal; Flumazenil; Humans; Meperidine; Midazolam; Nitrous Oxide; Patient Satisfaction | 2000 |
Discriminative-stimulus effects of triazolam and midazolam in rhesus monkeys.
Topics: Animals; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Generalization, Stimulus; Hypnotics and Sedatives; Macaca mulatta; Male; Midazolam; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Triazolam | 1999 |
Effects of midazolam in the spinal nerve ligation model of neuropathic pain in rats.
Topics: Animals; Cold Temperature; Electrophysiology; Evoked Potentials; Flumazenil; GABA Modulators; Injections, Spinal; Injections, Subcutaneous; Ligation; Male; Midazolam; Nerve Fibers; Nerve Fibers, Myelinated; Pain; Pain Measurement; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2000 |
Mice lacking the long splice variant of the gamma 2 subunit of the GABA(A) receptor are more sensitive to benzodiazepines.
Topics: Alternative Splicing; Animals; Azides; Benzodiazepines; Brain; Carbolines; Diazepam; Drug Resistance; Female; Flumazenil; GABA Modulators; Genetic Variation; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Midazolam; Pyridines; Receptors, GABA-A; Sleep; Zolpidem | 2000 |
Antagonism of the discriminative stimulus effects of positive gamma-aminobutyric acid(A) modulators in rhesus monkeys discriminating midazolam.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Diazepam; Discrimination Learning; Drug Antagonism; Female; Flumazenil; GABA Modulators; Macaca mulatta; Male; Midazolam; Receptors, GABA-A | 2000 |
Role of flumazenil for paradoxical reaction to midazolam during endoscopic procedures in children.
Topics: Adolescent; Adult; Child; Child, Preschool; Conscious Sedation; Endoscopy, Gastrointestinal; Female; Flumazenil; Humans; Male; Midazolam; Patient Compliance | 2000 |
Flumazenil's reversal of myoclonic-like movements associated with midazolam in term newborns.
Topics: Female; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Infant, Newborn; Male; Midazolam; Myoclonus | 2001 |
High-dose flumazenil potentiates the hypnotic activity of propofol, but not that of thiopental, in ddY mice.
Topics: Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Synergism; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Male; Mice; Midazolam; Propofol; Thiopental | 2001 |
Different types of GABA(A) receptors may mediate the anticonflict and response rate-decreasing effects of zaleplon, zolpidem, and midazolam in squirrel monkeys.
Topics: Acetamides; Animals; Carbolines; Dose-Response Relationship, Drug; Flumazenil; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; Hypnotics and Sedatives; Male; Midazolam; Pyridines; Pyrimidines; Reaction Time; Receptors, GABA-A; Saimiri; Zolpidem | 2001 |
Potency of positive gamma-aminobutyric acid(A) modulators to substitute for a midazolam discriminative stimulus in untreated monkeys does not predict potency to attenuate a flumazenil discriminative stimulus in diazepam-treated monkeys.
Topics: Animals; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Macaca mulatta; Male; Midazolam; Receptors, GABA-A; Steroids | 2001 |
Discriminative stimulus effects of benzodiazepine (BZ)(1) receptor-selective ligands in rhesus monkeys.
Topics: Acetamides; Animals; Carbolines; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Ligands; Macaca mulatta; Midazolam; Pyridines; Pyrimidines; Receptors, GABA-A; Zolpidem | 2002 |
[Parenteral sedation in oral surgical procedures].
Topics: Antidotes; Benzodiazepines; Conscious Sedation; Diazepam; Flumazenil; Humans; Hypoxia; Infusions, Parenteral; Midazolam; Monitoring, Physiologic; Oral Surgical Procedures; Oximetry | 1996 |
Flumazenil recovers diaphragm muscle dysfunction caused by midazolam in dogs.
Topics: Anesthetics, Intravenous; Animals; Antidotes; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Flumazenil; Hemodynamics; Male; Midazolam; Muscle Contraction; Muscle, Skeletal; Muscular Diseases | 2002 |
Stereoselective discriminative stimulus effects of zopiclone in rhesus monkeys.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Macaca mulatta; Male; Midazolam; Piperazines; Stereoisomerism; Substance Withdrawal Syndrome | 2003 |
Discriminative stimulus effects of positive GABAA modulators and other anxiolytics, sedatives, and anticonvulsants in untreated and diazepam-treated monkeys.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Macaca mulatta; Male; Midazolam; Receptors, GABA-A; Steroids | 2003 |
The influence of midazolam and flumazenil on rat brain slices oxygen consumption.
Topics: Animals; Anti-Anxiety Agents; Brain Chemistry; Cerebral Cortex; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Midazolam; Neurotransmitter Agents; Oxygen Consumption; Rats; Receptors, GABA-A | 2003 |
Evaluation of the reinforcing and discriminative stimulus effects of 1,4-butanediol and gamma-butyrolactone in rhesus monkeys.
Topics: 4-Butyrolactone; Animals; Butylene Glycols; Discrimination Learning; Flumazenil; GABA Modulators; Injections, Intravenous; Macaca mulatta; Male; Midazolam; Pentobarbital; Receptors, GABA-A; Reinforcement, Psychology; Self Administration | 2003 |
Flumazenil is innocuous in a paroxysmal supraventricular tachycardia and radiofrequency ablation: a paediatric case report and review of the literature.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Intravenous; Catheter Ablation; Flumazenil; GABA Modulators; Humans; Male; Midazolam; Morphine; Tachycardia, Paroxysmal; Tachycardia, Supraventricular | 2003 |
Flumazenil reverses a paradoxical reaction to intravenous midazolam in a child with uneventful prior exposure to midazolam.
Topics: Anesthetics, Intravenous; Antidotes; Child; Female; Flumazenil; Humans; Midazolam; Time Factors | 2003 |
Biphasic action of midazolam on GABAA receptor-mediated responses in rat sacral dorsal commissural neurons.
Topics: Animals; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Antagonists; Midazolam; Neurons; Protein Kinase C; Rats; Receptors, GABA-A; Sacrum; Spinal Nerve Roots | 2003 |
[Once more: the care duty of the physician in ambulatory administration of sedatives. Decision of the Federal Court, 4/8/2003-VI ZR 265/02].
Topics: Accidents, Traffic; Automobile Driving; Flumazenil; Germany; Humans; Hypnotics and Sedatives; Injections, Intravenous; Malpractice; Midazolam; Outpatients | 2003 |
Reversible anesthesia of captive California sea lions (Zalophus californianus) with medetomidine, midazolam, butorphanol, and isoflurane.
Topics: Anesthetics, Combined; Anesthetics, Inhalation; Animals; Antidotes; Butorphanol; Dose-Response Relationship, Drug; Female; Flumazenil; Heart Rate; Hypnotics and Sedatives; Imidazoles; Immobilization; Isoflurane; Medetomidine; Midazolam; Naltrexone; Narcotic Antagonists; Narcotics; Respiration; Sea Lions; Time Factors | 2004 |
GABAA receptor modulation of trigeminovascular nociceptive neurotransmission by midazolam is antagonized by flumazenil.
Topics: Animals; Cats; Drug Interactions; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Midazolam; Migraine Disorders; Nociceptors; Receptors, GABA-A; Synaptic Transmission; Trigeminal Nuclei | 2004 |
Bidirectional effects of benzodiazepine binding site ligands in the elevated plus-maze: differential antagonism by flumazenil and beta-CCt.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding Sites; Carbolines; Drug Interactions; Flumazenil; GABA Modulators; Ligands; Male; Maze Learning; Mice; Midazolam; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Zolpidem | 2004 |
Benzodiazepine receptor-dependent modulation of neutrophil (PMN) free amino- and alpha-keto acid profiles or immune functions.
Topics: Adult; Amino Acids; Benzodiazepinones; Cells, Cultured; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Hydrogen Peroxide; Isoquinolines; Keto Acids; Male; Midazolam; Naloxone; Neutrophils; Peroxidase; Receptors, GABA-A; Superoxides | 2005 |
Bidirectional effects of benzodiazepine binding site ligands in the passive avoidance task: differential antagonism by flumazenil and beta-CCt.
Topics: Animals; Avoidance Learning; Binding Sites; Carbolines; Dose-Response Relationship, Drug; Electroshock; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Ligands; Male; Memory; Midazolam; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, GABA-A | 2005 |
Bidirectional effects of benzodiazepine binding site ligands on active avoidance acquisition and retention: differential antagonism by flumazenil and beta-CCt.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Benzodiazepines; Binding Sites; Carbolines; Convulsants; Dose-Response Relationship, Drug; Flumazenil; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; Habituation, Psychophysiologic; Injections, Intraperitoneal; Ligands; Male; Midazolam; Motor Activity; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Retention, Psychology; Zolpidem | 2005 |
Classic benzodiazepines modulate the open-close equilibrium in alpha1beta2gamma2L gamma-aminobutyric acid type A receptors.
Topics: Algorithms; Animals; Benzodiazepines; Binding Sites; Carbolines; Cattle; Electrophysiology; Flumazenil; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Ligands; Midazolam; Oocytes; Patch-Clamp Techniques; Plasmids; Xenopus laevis | 2005 |
Negative GABA(A) modulators attenuate the discriminative stimulus effects of benzodiazepines and the neuroactive steroid pregnanolone in rhesus monkeys.
Topics: Animals; Benzodiazepines; Carbolines; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; Macaca mulatta; Male; Midazolam; Pregnanolone; Receptors, GABA-A; Serotonin Antagonists; Serotonin Receptor Agonists | 2005 |
Pharmacological properties of GABAA receptors containing gamma1 subunits.
Topics: Animals; Azepines; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Midazolam; Oocytes; Protein Subunits; Pyrazoles; Receptors, GABA-A; Triazolam; Xenopus laevis | 2006 |
Acute and chronic effects of ramelteon in rhesus monkeys (Macaca mulatta): dependence liability studies.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzodiazepines; Conditioning, Classical; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Indenes; Macaca mulatta; Male; Methylcellulose; Midazolam; Neuropsychological Tests; Receptors, Melatonin; Substance-Related Disorders; Time Factors | 2006 |
Flumazenil mimics whereas midazolam abolishes ischemic preconditioning in a rabbit heart model of ischemia-reperfusion.
Topics: Animals; Disease Models, Animal; Flumazenil; Heart Rate; Ischemic Preconditioning, Myocardial; Midazolam; Myocardial Reperfusion Injury; Rabbits | 2006 |
Changes in relative potency among positive GABA(A) receptor modulators upon discontinuation of chronic benzodiazepine treatment in rhesus monkeys.
Topics: Animals; Behavior, Animal; Benzodiazepines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Lorazepam; Macaca mulatta; Male; Midazolam; Pentobarbital; Pregnanediones; Pregnanolone; Receptors, GABA-A; Substance Withdrawal Syndrome | 2007 |
Unplanned 'unconsciousness' at Caesarean section: hysteria or drug reaction?
Topics: Adult; Amides; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthetics, Intravenous; Anesthetics, Local; Antidotes; Blood Pressure; Central Nervous System Stimulants; Cesarean Section; Diagnosis, Differential; Elective Surgical Procedures; Ephedrine; Female; Flumazenil; Humans; Hysteria; Meperidine; Midazolam; Naloxone; Narcotic Antagonists; Pregnancy; Ropivacaine; Unconsciousness | 2007 |
Fast cardiologist-administered midazolam for electrical cardioversion of atrial fibrillation.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthetics, Intravenous; Atrial Fibrillation; Cardiology; Conscious Sedation; Dose-Response Relationship, Drug; Electric Countershock; Female; Flumazenil; GABA Modulators; Heart Rate; Humans; Injections, Intravenous; Male; Midazolam; Middle Aged; Oxygen; Physician's Role; Research Design; Treatment Outcome | 2007 |
Flumazenil-sensitive dose-related physical dependence in planarians produced by two benzodiazepine and one non-benzodiazepine benzodiazepine-receptor agonists.
Topics: Analysis of Variance; Animals; Benzodiazepines; Clorazepate Dipotassium; Dose-Response Relationship, Drug; Flumazenil; GABA Agonists; GABA Modulators; Locomotion; Midazolam; Planarians; Pyridines; Receptors, GABA-A; Reproducibility of Results; Substance Withdrawal Syndrome; Substance-Related Disorders; Zolpidem | 2007 |
Brain activity affects dynamic but not static autoregulation.
Topics: Animals; Blood Flow Velocity; Blood Volume; Brain; Carotid Artery, Internal; Cerebrovascular Circulation; Constriction, Pathologic; Electric Stimulation; Evoked Potentials, Somatosensory; Flumazenil; Forelimb; GABA Modulators; Homeostasis; Hyperemia; Laser-Doppler Flowmetry; Male; Midazolam; Neural Inhibition; Rats; Rats, Inbred Strains | 2007 |
Decreased Efficacy of GABAA-receptor modulation by midazolam in the kainate model of temporal lobe epilepsy.
Topics: Animals; Autoradiography; Beta Rhythm; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Flumazenil; Injections, Intraperitoneal; Kainic Acid; Midazolam; Rats; Receptors, GABA-A; Status Epilepticus; Treatment Outcome; Tritium | 2007 |
Antagonistic effects of atipamezole, flumazenil and 4-aminopyridine against anaesthesia with medetomidine, midazolam and ketamine combination in cats.
Topics: 4-Aminopyridine; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Arousal; Body Temperature; Cats; Dose-Response Relationship, Drug; Flumazenil; Heart Rate; Imidazoles; Injections, Intravenous; Injections, Subcutaneous; Ketamine; Male; Medetomidine; Midazolam | 2008 |
Partial antagonization of midazolam-medetomidine-ketamine in cats--atipamezole versus combined atipamezole and flumazenil.
Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Heart Rate; Imidazoles; Injections, Intravenous; Injections, Subcutaneous; Ketamine; Male; Medetomidine; Midazolam; Respiration; Time Factors | 2007 |
Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Catecholamines; Corticosterone; Dimethyl Sulfoxide; Disease Models, Animal; Double-Blind Method; Drug Evaluation, Preclinical; Flavonoids; Flumazenil; Male; Maze Learning; Midazolam; Passiflora; Phytotherapy; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2007 |
Rectal Flumazenil can save the day.
Topics: Administration, Rectal; Anesthesia Recovery Period; Anti-Anxiety Agents; Antidotes; Cataract; Cataract Extraction; Female; Flumazenil; Humans; Infant; Midazolam; Monitoring, Physiologic; Oximetry; Tonometry, Ocular | 2008 |
Investigation of the anxiolytic effects of linalool, a lavender extract, in the male Sprague-Dawley rat.
Topics: Acyclic Monoterpenes; Animals; Anti-Anxiety Agents; Antidotes; Anxiety; Behavior, Animal; Disease Models, Animal; Drug Evaluation, Preclinical; Epinephrine; Flumazenil; GABA Modulators; Lavandula; Locomotion; Male; Maze Learning; Midazolam; Monoterpenes; Motor Skills; Multivariate Analysis; Norepinephrine; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2008 |
Midazolam attenuates the antinociception induced by d-serine or morphine at the supraspinal level in rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Injections, Intraventricular; Male; Midazolam; Morphine; Pain Measurement; Rats; Rats, Wistar; Serine; Spinal Cord | 2008 |
Inflammation-induced shift in the valence of spinal GABA-A receptor-mediated modulation of nociception in the adult rat.
Topics: Animals; Antineoplastic Agents; Flumazenil; Freund's Adjuvant; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hyperalgesia; Inflammation; Injections, Spinal; Isoquinolines; Male; Midazolam; Muscimol; Nociceptors; Pain Measurement; Pain Threshold; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Signal Transduction; Spinal Cord | 2008 |
Intra-periaqueductal gray matter injections of midazolam fail to alter anxiety in plus-maze experienced mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Avoidance Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Fear; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Maze Learning; Mice; Midazolam; Neural Inhibition; Periaqueductal Gray; Receptors, GABA-A; Synaptic Transmission | 2008 |
[Patient awakening from anesthesia was re-sedated by administration of flumazenil].
Topics: Aged, 80 and over; Anesthesia Recovery Period; Drug Synergism; Female; Flumazenil; Humans; Hypnotics and Sedatives; Midazolam; Propofol | 2008 |
Reduced midazolam clearance must be considered in prolonged coma.
Topics: Adult; Anesthetics, Intravenous; Antidotes; Cholinesterase Inhibitors; Coma; Flumazenil; Humans; Male; Metabolic Clearance Rate; Midazolam; Naloxone; Narcotic Antagonists; Physostigmine; Time | 2008 |
Investigation of the anxiolytic effects of luteolin, a lemon balm flavonoid in the male Sprague-Dawley rat.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Drug Therapy, Combination; Flumazenil; GABA Modulators; Luteolin; Male; Midazolam; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2009 |
Similar anxiolytic-like effects following intra-amygdala infusions of benzodiazepine receptor agonist and antagonist: evidence for the release of an endogenous benzodiazepine inverse agonist in mice exposed to elevated plus-maze test.
Topics: Amygdala; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Catheterization; Exploratory Behavior; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Maze Learning; Mice; Microinjections; Midazolam; Motor Activity | 2009 |
The effects of benzodiazepines on urotensin II-stimulated norepinephrine release from rat cerebrocortical slices.
Topics: Animals; Benzodiazepines; Benzoxazoles; Calcium Signaling; Cell Line; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; GABA-A Receptor Agonists; Humans; Hypnotics and Sedatives; In Vitro Techniques; Male; Midazolam; Naphthyridines; Norepinephrine; Orexin Receptors; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, GABA-A; Receptors, Neuropeptide; Transfection; Urea; Urotensins | 2009 |
Paradoxical reaction to midazolam reversed with flumazenil in a patient undergoing tumescent liposuction.
Topics: Antidotes; Axilla; Female; Flumazenil; GABA-A Receptor Antagonists; Humans; Hyperhidrosis; Hypnotics and Sedatives; Lipectomy; Midazolam; Middle Aged; Psychomotor Agitation | 2009 |
Neonatal allopregnanolone increases novelty-directed locomotion and disrupts behavioural responses to GABA(A) receptor modulators in adulthood.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Exploratory Behavior; Flumazenil; GABA Modulators; Isoxazoles; Lorazepam; Male; Maze Learning; Midazolam; Motor Activity; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A | 2009 |
Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations.
Topics: Adjuvants, Anesthesia; Administration, Intranasal; Anesthesia, Dental; Antidotes; Child, Preschool; Dental Restoration, Temporary; Female; Flumazenil; Humans; Laryngismus; Midazolam; Naloxone; Narcotic Antagonists; Oxygen; Sufentanil; Treatment Outcome | 2009 |
Antagonism of the ethanol-like discriminative stimulus effects of ethanol, pentobarbital, and midazolam in cynomolgus monkeys reveals involvement of specific GABA(A) receptor subtypes.
Topics: Animals; Azides; Benzodiazepines; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; Female; Flumazenil; Macaca fascicularis; Male; Midazolam; Pentobarbital; Protein Subunits; Receptors, GABA-A | 2009 |
The effect of midazolam on mouse Leydig cell steroidogenesis and apoptosis.
Topics: Anesthetics; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Cells, Cultured; Flumazenil; Gene Expression; Indoles; Isoquinolines; Leydig Cells; Male; Maleimides; Mice; Mice, Inbred C57BL; Midazolam; Protein Kinase C; Protein Kinase Inhibitors; Steroids; Sulfonamides | 2010 |
Midazolam-related drug interactions: detection of risk situations to the patient safety in a brazilian teaching hospital.
Topics: Antihypertensive Agents; Central Nervous System Depressants; Cytochrome P-450 CYP3A; Drug Interactions; Flumazenil; GABA Modulators; Humans; Medical Order Entry Systems; Midazolam | 2009 |
Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations: comment.
Topics: Administration, Intranasal; Antidotes; Child; Child Behavior; Conscious Sedation; Deep Sedation; Dental Restoration, Permanent; Flumazenil; Humans; Hypnotics and Sedatives; Midazolam; Naloxone; Narcotic Antagonists | 2010 |
Safety of transesophageal echocardiography in adults: study in a multidisciplinary hospital.
Topics: Aged; Anesthetics, Intravenous; Brazil; Conscious Sedation; Dose-Response Relationship, Drug; Echocardiography, Transesophageal; Feasibility Studies; Female; Flumazenil; Hospitals, General; Humans; Hypoxia; Male; Midazolam; Middle Aged; Mitral Valve Insufficiency; Multivariate Analysis; Prospective Studies; Risk Factors; Stroke Volume | 2009 |
Pharmacological characterization of the discriminative stimulus of inhaled 1,1,1-trichloroethane.
Topics: Administration, Inhalation; Animals; Binding Sites; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flumazenil; Male; Mice; Mice, Inbred Strains; Midazolam; Morphine; Phencyclidine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Receptors, Opioid, mu; Signal Transduction; Trichloroethanes | 2010 |
[Transient decerebrate rigidity from hypoxemia during administration of propofol, midazolam-flumazenil, and remifentanil-naloxone].
Topics: Airway Obstruction; Anesthetics, Intravenous; Bradycardia; Cardiotonic Agents; Cholangiopancreatography, Endoscopic Retrograde; Choledocholithiasis; Decerebrate State; Flumazenil; GABA Agonists; Humans; Hypnotics and Sedatives; Hypoxia; Intraoperative Complications; Intubation, Intratracheal; Male; Midazolam; Middle Aged; Naloxone; Piperidines; Propofol; Remifentanil; Sleep Apnea, Obstructive | 2010 |
Effects of a novel benzodiazepine derivative, JM-1232(-), on human gastroepiploic artery in vitro.
Topics: Dose-Response Relationship, Drug; Endothelium, Vascular; Flumazenil; GABA Modulators; Gastroepiploic Artery; Humans; In Vitro Techniques; Isoindoles; Midazolam; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Narcotic Antagonists; Norepinephrine; Piperazines; Potassium; Propofol; Structure-Activity Relationship; Vasoconstrictor Agents | 2011 |
[Case report: a 65-year-old man loses consciousness after colonoscopy].
Topics: Aged; Ambulatory Care; Anesthetics, Intravenous; Atropine; Bradycardia; Cholinergic Antagonists; Colonoscopy; Conscious Sedation; Diagnosis, Differential; Emergency Medical Services; Flumazenil; GABA Modulators; Hospitals, Rural; Humans; Hypnotics and Sedatives; Male; Midazolam; Muscarinic Antagonists; Propofol; Telephone; Unconsciousness | 2010 |
Paradoxical reaction following administration of a benzodiazepine.
Topics: Adolescent; Anesthesia, Dental; Anesthetics, Intravenous; Antidotes; Female; Flumazenil; GABA-A Receptor Antagonists; Humans; Hypnotics and Sedatives; Midazolam; Molar, Third; Premedication; Psychomotor Agitation; Tooth Extraction; Tooth, Impacted | 2010 |
Comparing the discriminative stimuli produced by either the neuroactive steroid pregnanolone or the benzodiazepine midazolam in rats.
Topics: Animals; Behavior, Animal; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; GABA Modulators; Male; Midazolam; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2011 |
The use of flumazenil after midazolam-induced conscious sedation.
Topics: Adult; Anesthesia, Dental; Anesthetics, Intravenous; Antidotes; Conscious Sedation; Dental Audit; Flumazenil; Humans; Midazolam; Prospective Studies | 2010 |
The fallacy of a lifesaving sublingual injection of flumazenil.
Topics: Anesthesia Recovery Period; Antidotes; Benzodiazepines; Conscious Sedation; Drug Overdose; Flumazenil; GABA Modulators; Humans; Hypnotics and Sedatives; Hypoxia, Brain; Injections; Injections, Intramuscular; Injections, Intravenous; Midazolam; Receptors, GABA-A; Respiration, Artificial; Triazolam | 2011 |
Chronic benzodiazepine treatment does not alter interactions between positive GABA(A) modulators and flumazenil or pentylenetetrazole in monkeys.
Topics: Animals; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Female; Flumazenil; GABA Modulators; Macaca mulatta; Male; Midazolam; Pentylenetetrazole; Receptors, GABA-A | 2011 |
Evaluation of the anxiolytic properties of myristicin, a component of nutmeg, in the male Sprague-Dawley rat.
Topics: Allylbenzene Derivatives; Animals; Anti-Anxiety Agents; Anxiety; Benzyl Compounds; Dioxolanes; Drug Evaluation, Preclinical; Flumazenil; GABA Modulators; Male; Maze Learning; Midazolam; Myristica; Nurse Anesthetists; Pyrogallol; Rats | 2011 |
Complications associated with intravenous midazolam sedation in anxious dental patients.
Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthetics, Intravenous; Child; Clinical Audit; Conscious Sedation; Drug Overdose; Female; Flumazenil; GABA Modulators; Humans; Male; Midazolam; Middle Aged; Prospective Studies; Regression Analysis; Respiratory Insufficiency; Statistics, Nonparametric; Syncope; Young Adult | 2011 |
Quantitative analyses of antagonism: combinations of midazolam and either flunitrazepam or pregnanolone in rhesus monkeys discriminating midazolam.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; Flunitrazepam; Macaca mulatta; Midazolam; Pregnanolone; Receptors, GABA-A | 2012 |
Hiccups induced by midazolam during sedation in flexible bronchoscopy.
Topics: Adenocarcinoma; Bronchoscopy; Conscious Sedation; Female; Flumazenil; GABA Modulators; Hiccup; Humans; Hypnotics and Sedatives; Lung Neoplasms; Metoclopramide; Midazolam; Middle Aged | 2012 |
Evaluation of the anxiolytic properties of tetrahydropalmatine, a Corydalis yanhusuo compound, in the male Sprague-Dawley rat.
Topics: Animals; Anti-Anxiety Agents; Corydalis; Drug Therapy, Combination; Drugs, Chinese Herbal; Flumazenil; GABA Modulators; Male; Maze Learning; Midazolam; Motor Skills; Multivariate Analysis; Phytotherapy; Prospective Studies; Rats; Rats, Sprague-Dawley | 2011 |
Postoperative global amnesia reversed with flumazenil.
Topics: Amnesia; Analgesics; Anesthesia, General; Cholangiopancreatography, Endoscopic Retrograde; Desflurane; Diabetes Mellitus, Type 2; Fentanyl; Flumazenil; GABA Modulators; Humans; Hydromorphone; Isoflurane; Male; Midazolam; Middle Aged; Pancreatitis; Postoperative Complications; Propofol | 2012 |
Antagonistic effect of flumazenil after midazolam sedation on arterial-cardiac baroreflex.
Topics: Adult; Baroreflex; Electrocardiography; Electroencephalography; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam; Systole | 2013 |
Acute tolerance to chlordiazepoxide qualitatively changes the interaction between flumazenil and pregnanolone and not the interaction between flumazenil and midazolam in rhesus monkeys discriminating midazolam.
Topics: Animals; Benzodiazepines; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Female; Flumazenil; GABA Modulators; Macaca mulatta; Midazolam; Pregnanolone | 2013 |
Discriminative stimulus effects of pregnanolone in rhesus monkeys.
Topics: Animals; Conditioning, Operant; Data Interpretation, Statistical; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flumazenil; Flunitrazepam; GABA Modulators; Gonadal Steroid Hormones; Hypnotics and Sedatives; Isoxazoles; Macaca mulatta; Male; Midazolam; Pregnanolone; Receptors, GABA-A; Reinforcement Schedule | 2014 |
Quantitative pharmacological analyses of the interaction between flumazenil and midazolam in monkeys discriminating midazolam: Determination of the functional half life of flumazenil.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Electroshock; Female; Flumazenil; GABA Modulators; Half-Life; Macaca mulatta; Male; Midazolam | 2014 |
Significant and safe shortening of the recovery time after flumazenil-reversed midazolam sedation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Conscious Sedation; Endoscopy, Digestive System; Feasibility Studies; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Patient Satisfaction; Recovery of Function; Young Adult | 2014 |
Paradoxical reaction to midazolam in patients undergoing endoscopy under sedation: Incidence, risk factors and the effect of flumazenil.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Endoscopy, Gastrointestinal; Female; Flumazenil; Hostility; Humans; Hyperkinesis; Hypnotics and Sedatives; Incidence; Male; Meperidine; Midazolam; Middle Aged; Narcotics; Prospective Studies; Risk Factors; Sex Factors; Young Adult | 2014 |
Reducing risk of overdose with midazolam injection in adults: an evaluation of change in clinical practice to improve patient safety in England.
Topics: Antidotes; Dose-Response Relationship, Drug; Drug Overdose; England; Flumazenil; Health Knowledge, Attitudes, Practice; Humans; Hypnotics and Sedatives; Injections; Medication Errors; Midazolam; Patient Safety; Risk Reduction Behavior; Safety Management; State Medicine | 2015 |
Effects in cats of atipamezole, flumazenil and 4-aminopyridine on stress-related neurohormonal and metabolic responses induced by medetomidine, midazolam and ketamine.
Topics: 4-Aminopyridine; Anesthesia; Anesthetics, Combined; Animals; Arousal; Cats; Dose-Response Relationship, Drug; Flumazenil; Imidazoles; Ketamine; Medetomidine; Midazolam; Respiration | 2015 |
Effect of flumazenil on diaphragm electrical activation during weaning from mechanical ventilation after acute respiratory distress syndrome.
Topics: Adult; Aged; Aged, 80 and over; Blood Gas Analysis; Diaphragm; Electrophysiological Phenomena; Female; Flumazenil; GABA Modulators; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Respiratory Distress Syndrome; Tidal Volume; Ventilator Weaning | 2015 |
Successful flumazenil reversal of paradoxical reaction to midazolam in a child.
Topics: Akathisia, Drug-Induced; Anti-Anxiety Agents; Antidotes; Child, Preschool; Delirium; Female; Flumazenil; Humans; Midazolam | 2015 |
The Effects of Flumazenil After Midazolam Sedation on Cerebral Blood Flow and Dynamic Cerebral Autoregulation in Healthy Young Males.
Topics: Adult; Arterial Pressure; Cerebrovascular Circulation; Conscious Sedation; Consciousness Monitors; Electroencephalography; Flumazenil; GABA Modulators; Healthy Volunteers; Homeostasis; Humans; Hypnotics and Sedatives; Male; Midazolam; Respiratory Mechanics; Ultrasonography, Doppler, Transcranial; Young Adult | 2015 |
Risk Factors and Outcomes of Reversal Agent Use in Moderate Sedation During Endoscopy and Colonoscopy.
Topics: Age Factors; Anti-Arrhythmia Agents; Antidotes; Atropine; Body Mass Index; Bradycardia; Case-Control Studies; Colonoscopy; Conscious Sedation; Female; Fentanyl; Flumazenil; Health Status; Humans; Hypnotics and Sedatives; Hypotension; Hypoxia; Male; Midazolam; Middle Aged; Naloxone; Narcotic Antagonists; Sex Factors; Treatment Outcome | 2016 |
Antiseizure Activity of Midazolam in Mice Lacking δ-Subunit Extrasynaptic GABA(A) Receptors.
Topics: Animals; Anticonvulsants; Brain Chemistry; Female; Flumazenil; GABA Modulators; Hippocampus; Hypnotics and Sedatives; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Midazolam; Neurotransmitter Agents; Receptors, GABA-A; Seizures | 2015 |
GABAA-benzodiazepine receptors in the dorsomedial (Dm) telencephalon modulate restraint-induced antinociception in the fish Leporinus macrocephalus.
Topics: Analysis of Variance; Animals; Fishes; Flumazenil; Formaldehyde; GABA Modulators; Locomotion; Microinjections; Midazolam; Nociception; Pain; Pain Measurement; Receptors, GABA-A; Restraint, Physical; Telencephalon | 2015 |
Evaluation of the anxiolytic and antidepressant effects of asiatic acid, a compound from Gotu kola or Centella asiatica, in the male Sprague Dawley rat.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Centella; Depression; Disease Models, Animal; Flumazenil; Male; Midazolam; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Plant Preparations; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triterpenes | 2015 |
Emergence delirium with transient associative agnosia and expressive aphasia reversed by flumazenil in a pediatric patient.
Topics: Adjuvants, Anesthesia; Agnosia; Anesthesia, General; Aphasia, Broca; Child; Delirium; Female; Flumazenil; GABA-A Receptor Antagonists; Humans; Midazolam; Postoperative Complications | 2015 |
Conscious Sedation Using Midazolam and Sequential Flumazenil in Cirrhotic Patients for Prophylactic Endoscopic Variceal Ligation.
Topics: Adult; Aged; Aged, 80 and over; Antidotes; Conscious Sedation; Esophageal and Gastric Varices; Esophagoscopy; Female; Flumazenil; Gastrointestinal Hemorrhage; Humans; Hypnotics and Sedatives; Ligation; Liver Cirrhosis; Male; Midazolam; Middle Aged; Patient Satisfaction; Prophylactic Surgical Procedures | 2015 |
Comparing the discriminative stimulus effects of modulators of GABAA receptors containing α4-δ subunits with those of gaboxadol in rats.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Flumazenil; GABA Agonists; GABA Modulators; Isoxazoles; Male; Midazolam; Pregnanolone; Protein Subunits; Rats; Receptors, GABA-A | 2016 |
Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas.
Topics: Adult; Brain Neoplasms; Female; Flumazenil; GABA Modulators; Glioma; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Motor Disorders; Upper Extremity | 2019 |
Pharmacologic Unmasking of Neurologic Deficits: A Stress Test for the Brain.
Topics: Brain; Exercise Test; Flumazenil; Glioma; Humans; Midazolam; Upper Extremity | 2019 |
Benzodiazepines Suppress Neuromodulatory Effects of Pudendal Nerve Stimulation on Rat Bladder Nociception.
Topics: Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Female; Flumazenil; GABA Modulators; Midazolam; Motor Neurons; Muscle Contraction; Muscle, Smooth; Nociception; Pudendal Nerve; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Urinary Bladder | 2020 |
Adverse Drug Reaction: Midazolam-Induced Extrapyramidal Symptoms: A Case Report.
Topics: Basal Ganglia Diseases; Brachial Plexus Block; Female; Flumazenil; Fracture Fixation, Internal; GABA Modulators; Humans; Hypnotics and Sedatives; Midazolam; Middle Aged; Open Fracture Reduction; Radius Fractures; Treatment Outcome; Ultrasonography, Interventional | 2020 |
Postoperative expressive aphasia associated with intravenous midazolam administration: a 5-year retrospective case-control study.
Topics: Aged; Aphasia, Broca; Case-Control Studies; Double-Blind Method; Female; Flumazenil; Humans; Male; Midazolam; Retrospective Studies | 2020 |
Re-sleeping after reversal of remimazolam by flumazenil.
Topics: Benzodiazepines; Double-Blind Method; Flumazenil; Hypnotics and Sedatives; Midazolam | 2021 |
[Paradoxical reactions associated with midazolam conscious sedation].
Topics: Conscious Sedation; Cross-Sectional Studies; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam | 2021 |
Predicting the amount of flumazenil needed to antagonize remimazolam.
Topics: Benzodiazepines; Flumazenil; Humans; Hypnotics and Sedatives; Midazolam | 2021 |
Reversal effects of atipamezole, flumazenil, and 4-aminopyridine on bradycardia and increases in blood pressures induced by medetomidine, midazolam, and ketamine in isoflurane-anesthetized cats.
Topics: 4-Aminopyridine; Animals; Blood Pressure; Bradycardia; Cat Diseases; Cats; Flumazenil; Heart Rate; Imidazoles; Isoflurane; Ketamine; Medetomidine; Midazolam; Prospective Studies | 2022 |
Midazolam-Induced Hiccups Reversed by Flumazenil: A Case Report.
Topics: Flumazenil; Hiccup; Humans; Midazolam | 2021 |
High-Dose Benzodiazepines Positively Modulate GABA
Topics: Animals; Animals, Outbred Strains; Benzodiazepines; Clonazepam; Diazepam; Female; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Midazolam; Receptors, GABA-A; Xenopus laevis | 2021 |
Posttraumatic midazolam administration does not influence brain damage after experimental traumatic brain injury.
Topics: Animals; Benzodiazepines; Brain; Brain Injuries; Brain Injuries, Traumatic; Flumazenil; Humans; Mice; Midazolam; RNA, Messenger | 2022 |
Evaluation of maximum dose intravenous midazolam used in dental intravenous sedation: a West of Scotland regional audit.
Topics: Administration, Intravenous; Anesthesia, Dental; Conscious Sedation; Flumazenil; Humans; Hypnotics and Sedatives; Midazolam | 2022 |
Comparison of two injectable anaesthetic protocols in Egyptian fruit bats (Rousettus aegyptiacus) undergoing gonadectomy.
Topics: Anesthetics; Animals; Butorphanol; Castration; Chiroptera; Chlorides; Dexmedetomidine; Flumazenil; Hypnotics and Sedatives; Isoflurane; Ketamine; Midazolam; Sodium | 2022 |
Remimazolam should be antagonized by an adequate flumazenil.
Topics: Benzodiazepines; Flumazenil; Hypnotics and Sedatives; Midazolam | 2023 |
Re-sedation after a large dose of flumazenil.
Topics: Anesthesia; Benzodiazepines; Flumazenil; Midazolam | 2023 |
Reply to "Re-sedation after a large dose of flumazenil".
Topics: Anesthesia; Flumazenil; Midazolam | 2023 |