midazolam and cyclosporine

midazolam has been researched along with cyclosporine in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (10.26)	18.2507
2000's	17 (43.59)	29.6817
2010's	18 (46.15)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Dai, R; Liu, Y; She, M; Wu, Z	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Watkins, PB	1
Barr, DM; Hartwell, PS; Kunze, KL; Marsh, CL; McVicar, JP; Podoll, TD; Raisys, VA; Shen, DD; Thummel, KE; Trager, WF	1
Gonzalez, FJ; Korzekwa, KR; Nemec, J; Relling, MV; Schuetz, EG; Schuetz, JD	1
Bannon, P; De Maeght, S; L'Ecuyer, L; Villeneuve, JP	1
Davis, CL; Marsh, CL; Paine, MF; Raisys, VA; Shen, DD; Thummel, KE	1
Murakami, T; Nagai, J; Nasu, R; Sanemasa, M; Takano, M; Yumoto, R	1
Bigler, L; Follath, F; Ha, HR; Kozlik, P; Stieger, B	1
Dresser, GK; Kim, RB; Schwarz, UI; Wilkinson, GR	1
Cook, J; Hurst, SI; Williams, JA	1
Beijnen, JH; Schellens, JH; Schinkel, AH; Smit, JW; Sparidans, RW; van der Kruijssen, CM; van Herwaarden, AE; Wagenaar, E	1
Drewe, J; Gutmann, H; Huwyler, J; Wright, MB	1
Chalasani, NP; Gorski, JC; Hall, SD; Malireddy, SR; Pinto, AG	1
Johnson, TN; Thomson, M	1
Guengerich, FP; Murayama, N; Okada, Y; Shimizu, M; Yamazaki, H; Yanagida, C	1
de Hoon, J; Meersseman, W; Spriet, I; von Winckelmann, S; Willems, L; Wilmer, A	1
Fujimoto, K; Fukushima, K; Ito, Y; Kokuhu, T; Okamoto, M; Sugioka, N; Takada, K; Tanaka, Y; Yoshimura, N	1
Akashi, H; Kida, M; Mori, M; Mori, N; Murakami, T; Yokooji, T; Yoshihara, S	1
Bi, XL; Chen, LT; Di, LQ; Du, Q; Zhou, W	1
de Jonge, H; de Loor, H; Kuypers, DR; Vanrenterghem, Y; Verbeke, K	1
Amundsen, R; Åsberg, A; Christensen, H; Ohm, IK	1
Liu, L; Liu, X; Sai, Y; Wang, D; Wang, J; Xia, S; Xue, W	1
Aspeslet, LJ; Foster, RT; Freitag, DG; Huizinga, RB; Larouche, R; Ling, SY; Mayo, PR	1
Belhabib, G; Combes, A; Corvol, E; Farinotti, R; Fernandez, C; Fillâtre, P; Hasni, N; Lemaitre, F; Leprince, P; Leven, C; Luyt, CE	1
de Jonge, H; de Loor, H; Kuypers, DR; Vanhove, T; Verbeke, K	1
Kato, Y; Kogi, T; Masuo, Y; Nakamichi, N; Taguchi, T	1
Adeloye, T; Dennison, J; Endo, T; Johnston, A; Puri, A; Sahgal, O; Warrington, S	1

Reviews

4 review(s) available for midazolam and cyclosporine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
A significant drug-metabolizing role for CYP3A5? Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:12 Topics: Animals; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Microsomes, Liver; Midazolam; Pharmaceutical Preparations	2003
Intestinal metabolism and transport of drugs in children: the effects of age and disease. Journal of pediatric gastroenterology and nutrition, 2008, Volume: 47, Issue:1 Topics: Aging; Biological Availability; Child; Cyclosporine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gastrointestinal Transit; Humans; Intestinal Absorption; Intestine, Small; Liver; Midazolam; Tissue Distribution	2008
Mini-series: II. clinical aspects. clinically relevant CYP450-mediated drug interactions in the ICU. Intensive care medicine, 2009, Volume: 35, Issue:4 Topics: Acute Disease; Analgesics, Opioid; Anti-Bacterial Agents; Anticonvulsants; Benzodiazepines; Catecholamines; Chronic Disease; Critical Care; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Monitoring; Humans; Immunosuppressive Agents; Intensive Care Units; Midazolam; Tacrolimus	2009

Trials

3 trial(s) available for midazolam and cyclosporine

Article	Year
Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects. Clinical pharmacology and therapeutics, 2003, Volume: 73, Issue:1 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Cross-Over Studies; Cyclosporine; Cytochrome P-450 CYP3A; Drug Administration Schedule; Enzyme Induction; Female; Gene Expression Regulation; Genes, MDR; Humans; Hypericum; Intestinal Mucosa; Liver; Male; Midazolam; Middle Aged; Oxidoreductases, N-Demethylating; Plant Preparations; Reference Values; Terfenadine	2003
Cytochrome P450 3A and P-glycoprotein drug-drug interactions with voclosporin. British journal of clinical pharmacology, 2014, Volume: 77, Issue:6 Topics: Adolescent; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcineurin Inhibitors; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Drug Interactions; Female; Humans; Ketoconazole; Male; Midazolam; Middle Aged; Verapamil	2014
Amenamevir: Studies of Potential CYP3A-Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers. Clinical pharmacology in drug development, 2018, Volume: 7, Issue:8 Topics: Adolescent; Adult; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Healthy Volunteers; Humans; Male; Midazolam; Middle Aged; Oxadiazoles; Ritonavir; Young Adult	2018

Other Studies

32 other study(ies) available for midazolam and cyclosporine

Article	Year
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine	2003
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors. Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:3 Topics: Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Molecular Structure; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index	2014
Grapefruit juice interactions with drugs. The Medical letter on drugs and therapeutics, 1995, Aug-18, Volume: 37, Issue:955 Topics: Beverages; Caffeine; Citrus; Cyclosporine; Estrogens; Felodipine; Food-Drug Interactions; Humans; Midazolam; Nifedipine; Terfenadine	1995
Cyclosporine and liver transplantation: will the midazolam test make blood level monitoring obsolete? Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:3 Topics: Cyclosporine; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Humans; Liver; Liver Transplantation; Midazolam; Mixed Function Oxygenases	1995
Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:1 Topics: Cyclosporine; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Liver; Liver Transplantation; Metabolic Clearance Rate; Midazolam; Mixed Function Oxygenases	1994
O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. Molecular pharmacology, 1994, Volume: 45, Issue:2 Topics: Biotransformation; Catalysis; Catechols; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Etoposide; Humans; Methylation; Microsomes, Liver; Midazolam; Mixed Function Oxygenases; Teniposide	1994
Prediction of cyclosporine clearance in liver transplant recipients by the use of midazolam as a cytochrome P450 3A probe. Clinical pharmacology and therapeutics, 2000, Volume: 67, Issue:3 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Gas Chromatography-Mass Spectrometry; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Midazolam; Middle Aged; Oxidoreductases, N-Demethylating; Predictive Value of Tests	2000
Can oral midazolam predict oral cyclosporine disposition? European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 12, Issue:1 Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Metabolic Clearance Rate; Midazolam; Middle Aged; Oxidoreductases, N-Demethylating	2000
Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:2 Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biliary Tract; Blotting, Western; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Erythromycin; Intestinal Absorption; Intestines; Liver; Male; Midazolam; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar; Rhodamine 123; Substrate Specificity; Verapamil	2001
Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone. Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:5 Topics: Amiodarone; Animals; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Chromatography, High Pressure Liquid; Cimetidine; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ketoconazole; Kinetics; Microsomes, Liver; Midazolam; Models, Chemical; Oxidoreductases, N-Demethylating; Protein Isoforms; Quinidine; Rabbits; Rifampin; Time Factors	2001
Midazolam and cyclosporin a metabolism in transgenic mice with liver-specific expression of human CYP3A4. Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:7 Topics: Animals; Base Sequence; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA Primers; Humans; Liver; Male; Mice; Mice, Transgenic; Midazolam	2005
Induction of cytochrome P450 3A4 and P-glycoprotein by the isoxazolyl-penicillin antibiotic flucloxacillin. Current drug metabolism, 2006, Volume: 7, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Floxacillin; Genes, MDR; Hepatocytes; Humans; Hypnotics and Sedatives; Immunosuppressive Agents; LLC-PK1 Cells; Mice; Mice, Transgenic; Microsomes, Liver; Midazolam; Penicillins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine	2006
Altered first-pass effects in a liver transplant recipient explained intraindividual variation in calcineurin inhibitor concentrations: a case report. Transplantation proceedings, 2008, Volume: 40, Issue:5 Topics: Adult; Biopsy; Calcineurin Inhibitors; Cholangitis, Sclerosing; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Intestine, Small; Liver Transplantation; Male; Mass Spectrometry; Midazolam; Tacrolimus	2008
Drug interactions of thalidomide with midazolam and cyclosporine A: heterotropic cooperativity of human cytochrome P450 3A5. Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:1 Topics: Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Kinetics; Liver; Midazolam; Thalidomide	2009
Comparison of pharmacokinetics of cyclosporine A in cadaveric and living-related renal transplant recipients and in an experimental rat model of renal failure. Drug metabolism letters, 2009, Volume: 3, Issue:3 Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Animals; Area Under Curve; Child; Cyclosporine; Cytochrome P-450 CYP3A; Disease Models, Animal; Drug Monitoring; Duodenum; Female; Graft Rejection; Humans; Immunosuppressive Agents; Injections, Intravenous; Intestinal Absorption; Kidney Transplantation; Living Donors; Male; Midazolam; Middle Aged; Rats; Rats, Wistar; Renal Insufficiency; Reperfusion Injury; Retrospective Studies; Substrate Specificity; Young Adult	2009
Interaction of Rhei Rhizoma extract with cytochrome P450 3A and efflux transporters in rats. Die Pharmazie, 2010, Volume: 65, Issue:5 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carrier Proteins; Cyclosporine; Cytochrome P-450 CYP3A; Dinitrochlorobenzene; GABA Modulators; Glutathione; Immunosuppressive Agents; Indicators and Reagents; Intestinal Mucosa; Intestines; Liver; Male; Microsomes, Liver; Midazolam; Plant Extracts; Rats; Rats, Sprague-Dawley; Rheum; Rhodamine 123	2010
[Intestinal absorption of forsythoside A by rat circulation in situ]. Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:11 Topics: Animals; Colon; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Duodenum; Edetic Acid; Glycosides; Hydrogen-Ion Concentration; Ileum; Intestinal Absorption; Jejunum; Male; Mannitol; Midazolam; Rats; Rats, Sprague-Dawley	2010
In vivo CYP3A activity is significantly lower in cyclosporine-treated as compared with tacrolimus-treated renal allograft recipients. Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:3 Topics: Adult; Calcineurin; Calcineurin Inhibitors; Case-Control Studies; Cyclosporine; Cytochrome P-450 CYP3A; Drug Interactions; Female; Genotype; Humans; Immunosuppressive Agents; Kidney Transplantation; Liver; Male; Midazolam; Polymorphism, Single Nucleotide; Polypharmacy; Tacrolimus; Transplantation, Homologous	2011
Cyclosporine A- and tacrolimus-mediated inhibition of CYP3A4 and CYP3A5 in vitro. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:4 Topics: Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Immunosuppressive Agents; In Vitro Techniques; Microsomes, Liver; Midazolam; Nonlinear Dynamics; Substrate Specificity; Tacrolimus; Time Factors	2012
A semi-physiologically-based pharmacokinetic model characterizing mechanism-based auto-inhibition to predict stereoselective pharmacokinetics of verapamil and its metabolite norverapamil in human. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Nov-20, Volume: 50, Issue:3-4 Topics: Calcium Channel Blockers; Cyclosporine; Cytochrome P-450 CYP3A; Drug Interactions; Gastric Mucosa; Humans; Intestine, Small; Liver; Microsomes, Liver; Midazolam; Models, Biological; Simvastatin; Stereoisomerism; Verapamil	2013
Propofol, midazolam, vancomycin and cyclosporine therapeutic drug monitoring in extracorporeal membrane oxygenation circuits primed with whole human blood. Critical care (London, England), 2015, Feb-12, Volume: 19 Topics: Anti-Infective Agents; Blood; Critical Illness; Cyclosporine; Drug Monitoring; Extracorporeal Membrane Oxygenation; Humans; Hypnotics and Sedatives; Midazolam; Models, Biological; Polyvinyl Chloride; Propofol; Vancomycin	2015
Progressive decline in tacrolimus clearance after renal transplantation is partially explained by decreasing CYP3A4 activity and increasing haematocrit. British journal of clinical pharmacology, 2015, Volume: 80, Issue:3 Topics: Area Under Curve; Calcineurin Inhibitors; Cyclosporine; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Graft Rejection; Hematocrit; Humans; Kidney Transplantation; Longitudinal Studies; Male; Metabolic Clearance Rate; Midazolam; Middle Aged; Tacrolimus	2015
Characterization of Long-Lasting Oatp Inhibition by Typical Inhibitor Cyclosporine A and In Vitro-In Vivo Discrepancy in Its Drug Interaction Potential in Rats. Journal of pharmaceutical sciences, 2016, Volume: 105, Issue:7 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Cyclosporine; Drug Interactions; Hepatocytes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Midazolam; Organic Anion Transporters; Pravastatin; Protein Binding; Rats; Rats, Sprague-Dawley	2016