midazolam has been researched along with clotrimazole in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beck, WT; Schuetz, EG; Schuetz, JD | 1 |
| Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Higashikawa, F; Kaneda, T; Murakami, T; Takano, M | 1 |
| Badger, TM; Chen, Y; Jo, CH; Ronis, MJ; Simpson, P | 1 |
| Baum, CL; Camp, JR; Chan, LN; Jeong, HY; Molokie, RE; Shord, SS; Vasquez, EM; Xie, H | 1 |
1 review(s) available for midazolam and clotrimazole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for midazolam and clotrimazole
| Article | Year |
|---|---|
Effects of oral clotrimazole troches on the pharmacokinetics of oral and intravenous midazolam.
Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Anti-Anxiety Agents; Antifungal Agents; Area Under Curve; Clotrimazole; Cross-Over Studies; Cytochrome P-450 CYP3A; Drug Interactions; Female; Humans; Injections, Intravenous; Male; Metabolic Clearance Rate; Midazolam; Middle Aged | 2010 |
7 other study(ies) available for midazolam and clotrimazole
| Article | Year |
|---|---|
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Cell Line; Clotrimazole; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Primers; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Midazolam; Mixed Function Oxygenases; Molecular Sequence Data; Multigene Family; Phenobarbital; Phenytoin; Polymerase Chain Reaction; Rifampin; Tumor Cells, Cultured; Verapamil | 1996 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine | 2003 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
In-vivo and in-vitro metabolic clearance of midazolam, a cytochrome P450 3A substrate, by the liver under normal and increased enzyme activity in rats.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Aryl Hydrocarbon Hydroxylases; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Activation; In Vitro Techniques; Intestinal Mucosa; Liver; Male; Metabolic Clearance Rate; Microsomes, Liver; Midazolam; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley; Substrate Specificity; Time Factors | 1999 |
Diets containing soy protein isolate increase hepatic CYP3A expression and inducibility in weanling male rats exposed during early development.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Northern; Clotrimazole; Cytochrome P-450 CYP3A; Dexamethasone; Dietary Proteins; DNA Probes; DNA, Complementary; Liver; Male; Midazolam; Oxidoreductases, N-Demethylating; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Soybean Proteins; Testosterone; Transcription, Genetic | 2004 |