midazolam and antipyrine

midazolam has been researched along with antipyrine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's2 (13.33)18.2507
2000's6 (40.00)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coassolo, P; Lavé, T; Schneider, G1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Crevoisier, C; Himberg, JJ; Pentikäinen, PJ; Välisalmi, L1
Birnie, GG; Brodie, MJ; Cook, A; MacGilchrist, AJ; Murray, T; Scobie, G; Watkinson, G1
Allen, JG; Altman, JF; White, SM1
Alderson, J; Allen, JG; Galloway, DB; Hallett, C1
Mäenpää, J; Pelkonen, O; Raunio, H; Rautio, A; Taavitsainen, P1
Iwaki, M; Kawase, A; Tanino, T; Tsuji, A; Uno, S1

Reviews

1 review(s) available for midazolam and antipyrine

ArticleYear
Inhibition and induction of human cytochrome P450 (CYP) enzymes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1998, Volume: 28, Issue:12

    Topics: Antipyrine; Citalopram; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Humans; Inactivation, Metabolic; Liver; Midazolam; Smoking; Substrate Specificity

1998

Other Studies

14 other study(ies) available for midazolam and antipyrine

ArticleYear
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
    Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25

    Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats

1999
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Pharmacokinetics of midazolam following intravenous and oral administration in patients with chronic liver disease and in healthy subjects.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:3

    Topics: Administration, Oral; Adult; Aged; Antipyrine; Half-Life; Humans; Injections, Intravenous; Liver Cirrhosis; Male; Metabolic Clearance Rate; Midazolam; Middle Aged

1989
Pharmacokinetics and pharmacodynamics of intravenous midazolam in patients with severe alcoholic cirrhosis.
    Gut, 1986, Volume: 27, Issue:2

    Topics: Adult; Antipyrine; Benzodiazepines; Endoscopy; Flicker Fusion; Half-Life; Humans; Hypnotics and Sedatives; Indocyanine Green; Kinetics; Liver Cirrhosis, Alcoholic; Midazolam; Middle Aged; Preanesthetic Medication; Reaction Time

1986
The effect of midazolam administration on the pharmacokinetics of antipyrine in the rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:7

    Topics: Animals; Antipyrine; Dose-Response Relationship, Drug; Half-Life; Kinetics; Male; Metabolic Clearance Rate; Midazolam; Rats

1987
The effect of midazolam (Hypnovel) administration on antipyrine pharmacokinetics in humans.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:7

    Topics: Adult; Antipyrine; Female; Humans; Kinetics; Male; Midazolam; Middle Aged

1987
Decreased intestinal CYP3A and P-glycoprotein activities in rats with adjuvant arthritis.
    Drug metabolism and pharmacokinetics, 2007, Volume: 22, Issue:4

    Topics: Animals; Antipyrine; Arthritis, Experimental; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blotting, Western; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Diffusion Chambers, Culture; Female; Fluorescent Dyes; In Vitro Techniques; Intestinal Mucosa; Intestines; Microsomes; Midazolam; Ranitidine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger

2007