Compounds > midazolam

midazolam and alpha-naphthoflavone

midazolam has been researched along with alpha-naphthoflavone in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Dai, R; Liu, Y; She, M; Wu, Z1
Chen, F; Chen, W; Lan, L; Li, B; Li, J; Liu, Y; Mao, F; Ni, S; Wei, H; Zhu, J1
Hall, SD; Mäenpää, J; Ring, BJ; Strom, SC; Wrighton, SA1
Bigler, L; Follath, F; Ha, HR; Kozlik, P; Stieger, B1
Emoto, C; Iketaki, H; Nakajima, M; Satoh, T; Shimada, N; Shimizu, R; Suzuki, S; Yamasaki, S; Yamazaki, H; Yokoi, T1
Allen, KE; Cameron, MD; Campbell, AP; Kunze, KL; Nelson, SD; Roberts, AG; Schuman, JT; Wen, B1
Abbasi, A; Dangi, B; Davydov, DR; Davydova, NY; Maldonado, MA; Vavilov, NE; Zgoda, VG1

Other Studies

7 other study(ies) available for midazolam and alpha-naphthoflavone

ArticleYear
The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors.
    Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:3

    Topics: Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Molecular Structure; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2011
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity.
    Journal of medicinal chemistry, 2018, 01-11, Volume: 61, Issue:1

    Topics: Animals; Drug Design; Enzyme Inhibitors; ERG1 Potassium Channel; HEK293 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Methicillin-Resistant Staphylococcus aureus; Mice; Oxidoreductases; Rats; Safety; Solubility; Structure-Activity Relationship; Water

2018
Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone.
    Pharmacogenetics, 1998, Volume: 8, Issue:2

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Benzene Derivatives; Benzoflavones; Buffers; Calcium Chloride; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Magnesium Chloride; Microsomes, Liver; Midazolam; NADP; Oxidoreductases, N-Demethylating; Terfenadine; Testosterone

1998
Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone.
    Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:5

    Topics: Amiodarone; Animals; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Chromatography, High Pressure Liquid; Cimetidine; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ketoconazole; Kinetics; Microsomes, Liver; Midazolam; Models, Chemical; Oxidoreductases, N-Demethylating; Protein Isoforms; Quinidine; Rabbits; Rifampin; Time Factors

2001
Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:5

    Topics: Animals; Benzoflavones; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythromycin; GABA Modulators; Gastrointestinal Agents; Histamine H1 Antagonists; Humans; Inhibitory Concentration 50; Intestines; Kinetics; Mice; Microsomes; Microsomes, Liver; Midazolam; Mixed Function Oxygenases; Nifedipine; Oxygen; Protein Binding; Steroid Hydroxylases; Terfenadine; Testosterone; Vasodilator Agents

2001
Cooperative binding of midazolam with testosterone and alpha-naphthoflavone within the CYP3A4 active site: a NMR T1 paramagnetic relaxation study.
    Biochemistry, 2005, Nov-01, Volume: 44, Issue:43

    Topics: Benzoflavones; Binding Sites; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Heme; Kinetics; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Midazolam; Protons; Testosterone

2005
Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4.
    Archives of biochemistry and biophysics, 2021, 02-15, Volume: 698

    Topics: Amino Acid Sequence; Amitriptyline; Benzoflavones; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Enzyme Activators; Ethanol; Female; Humans; Ivermectin; Male; Microsomes, Liver; Midazolam; Nitrophenols; Quinolines

2021