Page last updated: 2024-08-24

mibefradil and itraconazole

mibefradil has been researched along with itraconazole in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A1
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Azimi, I; Denny, WA; Flanagan, JU; Inserra, M; Monteith, GR; Stevenson, RJ; Vetter, I1
Jacobson, TA1

Trials

1 trial(s) available for mibefradil and itraconazole

ArticleYear
Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors.
    The American journal of cardiology, 2004, Nov-01, Volume: 94, Issue:9

    Topics: Adolescent; Adult; Anticholesteremic Agents; Antiprotozoal Agents; Area Under Curve; Atorvastatin; Biomarkers; Calcium Channel Blockers; Clarithromycin; Creatine Kinase; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Itraconazole; Male; Mibefradil; Middle Aged; Pravastatin; Protein Synthesis Inhibitors; Pyrroles; Simvastatin; Verapamil

2004

Other Studies

4 other study(ies) available for mibefradil and itraconazole

ArticleYear
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
    Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine

2003
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca
    Bioorganic & medicinal chemistry, 2017, 01-01, Volume: 25, Issue:1

    Topics: Calcium Channel Blockers; Cell Line, Tumor; Databases, Chemical; Drug Stability; Fluorescence; HEK293 Cells; High-Throughput Screening Assays; Humans; ORAI1 Protein; Stereoisomerism; Structure-Activity Relationship; Triazoles

2017