Page last updated: 2024-08-24

mibefradil and ethosuximide

mibefradil has been researched along with ethosuximide in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (61.54)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Adarayan, ED; Ballard, JE; Barrow, JC; Bock, MG; Bunting, PB; Connolly, TM; DiLella, AG; Doran, SM; Fox, SV; Graufelds, VK; Hartman, GD; Koblan, KS; Kraus, RL; Kuo, Y; Lindsley, CW; Magee, MM; Marino, MJ; Nuss, CE; Prueksaritanont, T; Renger, JJ; Reynolds, IJ; Rittle, KE; Schlegel, KA; Shipe, WD; Shu, Y; Tang, C; Uebele, VN; Vargas, HM; Woltmann, RF; Yang, FV; Yang, ZQ; Zrada, MM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Du Nguyen, H; Horaguchi, Y; Kasanami, Y; Kawabata, A; Kitamura, S; Nishikawa, H; Okada, T; Sekiguchi, F; Toyooka, N; Tsubota, M; Yamaoka, S; Yoshida, S1
Antepohl, W; Haaf, O; Herzig, S; Huber, I; Matthes, J; Striessnig, J1
Dogrul, A; Gardell, LR; Lai, J; Ossipov, MH; Porreca, F; Tulunay, FC1
Barton, ME; Eberle, EL; Shannon, HE1
Castro-Alamancos, MA; Rigas, P; Tawara-Hirata, Y1
Chen, CC; Cheng, JK; Chiou, LC; Lin, CS; Yang, JR1
Broicher, T; Budde, T; Kanyshkova, T; Meuth, P; Meuth, SG; Munsch, T; Pape, HC; Seidenbecher, T1
Chang, YF; Chen, YL; Cheng, JK; Hung, YC; Lin, CS; Shiue, SJ; Tsaur, ML; Wang, SW; Wang, TY; Wang, YC1
Aceto, R; Bootman, MD; Chandler, S; Crea, F; Matheou, C; Mather, R; Pucci, P; Rietdorf, K; Rigas, SH; Silvestri, R; Venalainen, E; Wang, Y1

Other Studies

13 other study(ies) available for mibefradil and ethosuximide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Discovery of 1,4-substituted piperidines as potent and selective inhibitors of T-type calcium channels.
    Journal of medicinal chemistry, 2008, Oct-23, Volume: 51, Issue:20

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Cardiovascular System; Drug Evaluation, Preclinical; Humans; Molecular Structure; Piperidines; Rats; Structure-Activity Relationship

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Design and synthesis of novel anti-hyperalgesic agents based on 6-prenylnaringenin as the T-type calcium channel blockers.
    Bioorganic & medicinal chemistry, 2018, 08-15, Volume: 26, Issue:15

    Topics: Action Potentials; Analgesics; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; Drug Design; Flavonoids; HEK293 Cells; Humans; Inhibitory Concentration 50; Male; Mice; Neuralgia; Patch-Clamp Techniques; Structure-Activity Relationship

2018
Pharmacodynamic interaction between mibefradil and other calcium channel blockers.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:6

    Topics: Amlodipine; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Cell Membrane; Dihydropyridines; Drug Interactions; Ethosuximide; Female; Gallopamil; Humans; In Vitro Techniques; Isradipine; Male; Mibefradil; Myocardial Contraction; Perfusion; Radioligand Assay; Rats; Rats, Wistar; Ventricular Pressure

2000
Reversal of experimental neuropathic pain by T-type calcium channel blockers.
    Pain, 2003, Volume: 105, Issue:1-2

    Topics: Administration, Topical; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Dose-Response Relationship, Drug; Ethosuximide; Foot; Hot Temperature; Injections, Intraperitoneal; Injections, Spinal; Ligation; Male; Mibefradil; Neuralgia; Rats; Rats, Sprague-Dawley; Spinal Nerves; Touch; Wounds, Nonpenetrating

2003
The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil.
    European journal of pharmacology, 2005, Oct-03, Volume: 521, Issue:1-3

    Topics: Animals; Anticonvulsants; Behavior, Animal; Calcium Channel Blockers; Calcium Channels, T-Type; Dose-Response Relationship, Drug; Ethosuximide; Hyperalgesia; Male; Mibefradil; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Time Factors; Trimethadione

2005
Resonance (approximately 10 Hz) of excitatory networks in motor cortex: effects of voltage-dependent ion channel blockers.
    The Journal of physiology, 2007, Jan-01, Volume: 578, Issue:Pt 1

    Topics: Anesthetics, Local; Animals; Calcium Channel Blockers; Electrophysiology; Ethosuximide; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ion Channels; Magnesium; Mibefradil; Mice; Motor Cortex; Neocortex; Phenytoin; Potassium Channel Blockers; Potassium Channels; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Riluzole; Sodium Channel Blockers; Tetrodotoxin

2007
Effects of intrathecal injection of T-type calcium channel blockers in the rat formalin test.
    Behavioural pharmacology, 2007, Volume: 18, Issue:1

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; Dose-Response Relationship, Drug; Ethosuximide; Formaldehyde; Hindlimb; Injections, Spinal; Long-Term Potentiation; Male; Mibefradil; Neural Inhibition; Neuronal Plasticity; Nickel; Nociceptors; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Cord

2007
T-current related effects of antiepileptic drugs and a Ca2+ channel antagonist on thalamic relay and local circuit interneurons in a rat model of absence epilepsy.
    Neuropharmacology, 2007, Volume: 53, Issue:3

    Topics: Animals; Animals, Newborn; Anticonvulsants; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Ethosuximide; Interneurons; Membrane Potentials; Mibefradil; Patch-Clamp Techniques; Rats; Rats, Inbred ACI; Thalamus

2007
Chronic intrathecal infusion of mibefradil, ethosuximide and nickel attenuates nerve ligation-induced pain in rats.
    British journal of anaesthesia, 2015, Volume: 115, Issue:1

    Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Disease Models, Animal; Ethosuximide; Ligation; Male; Mibefradil; Neuralgia; Nickel; Rats; Rats, Sprague-Dawley

2015
T-type calcium channels drive the proliferation of androgen-receptor negative prostate cancer cells.
    The Prostate, 2019, Volume: 79, Issue:13

    Topics: Calcium Channel Blockers; Calcium Channels, T-Type; Cell Line, Tumor; Cell Proliferation; Ethosuximide; Humans; Male; Mibefradil; Molecular Targeted Therapy; PC-3 Cells; Prognosis; Prostatic Neoplasms; Receptors, Androgen; Up-Regulation

2019