Compounds > mibefradil

Page last updated: 2024-08-24

mibefradil and caffeine

mibefradil has been researched along with caffeine in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (6.67)	18.2507
2000's	5 (33.33)	29.6817
2010's	9 (60.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Coassolo, P; Lavé, T; Schneider, G	1
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Campillo, NE; Guerra, A; Páez, JA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN	1
Brain, KL; Cunnane, TC; Cuprian, AM; Williams, DJ	1
Kito, Y; Sanders, KM; Ward, SM	1
Hu, X; Huang, J; Lu, L; Luo, Z; Ye, Z	1

Other Studies

15 other study(ies) available for mibefradil and caffeine

Article	Year
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques. Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25 Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently. Chemical biology & drug design, 2016, Volume: 88, Issue:6 Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain	2016
The sources and sequestration of Ca(2+) contributing to neuroeffector Ca(2+) transients in the mouse vas deferens. The Journal of physiology, 2003, Dec-01, Volume: 553, Issue:Pt 2 Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels, T-Type; Calcium Signaling; Chelating Agents; Electric Stimulation; Electrophysiology; In Vitro Techniques; Indoles; Male; Mibefradil; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Models, Biological; Muscle Contraction; Muscle, Smooth; Nickel; Prazosin; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Ryanodine; Thapsigargin; Vas Deferens	2003
Pacemaker potentials generated by interstitial cells of Cajal in the murine intestine. American journal of physiology. Cell physiology, 2005, Volume: 288, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Biological Clocks; Caffeine; Calcium Channel Blockers; Central Nervous System Stimulants; Electrophysiology; Glyburide; In Vitro Techniques; Intestine, Small; Membrane Potentials; Mibefradil; Mice; Mice, Inbred BALB C; Myocytes, Smooth Muscle; Nifedipine; Pinacidil; Vasodilator Agents	2005
Electrical stimulation induces calcium-dependent release of NGF from cultured Schwann cells. Glia, 2010, Volume: 58, Issue:5 Topics: Analysis of Variance; Animals; Animals, Newborn; Biophysics; Botulinum Toxins, Type A; Cadmium Chloride; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Chelating Agents; Cytochalasins; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Estrenes; Exocytosis; Mibefradil; Neomycin; Nerve Growth Factor; Nocodazole; Phosphodiesterase Inhibitors; Protein Synthesis Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; S100 Proteins; Schwann Cells; Tubulin Modulators	2010