mianserin and prazosin

mianserin has been researched along with prazosin in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199017 (48.57)18.7374
1990's10 (28.57)18.2507
2000's5 (14.29)29.6817
2010's3 (8.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Janssen, CG; Laduron, PM; Thijssen, JB; Van Dun, J; Wouters, W1
Andrews, PR; Craik, DJ; Martin, JL1
Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
Topliss, JG; Yoshida, F1
Andersen, K; Balle, T; Larsen, AK; Liljefors, T; Perregaard, J; Ramirez, MT; Søby, KK1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Roba, J; van Dorsser, W1
Maj, J; Rogóz, Z; Skuza, G; Sowińska, H1
Barker, EL; Burris, KD; Sanders-Bush, E1
Maj, J; Rogóz, Z; Skuza, G1
De Boer, T; De Vos, CJ; Tonnaer, JA; Van Delft, AM1
Koyama, T; Mikuni, M; Mori, H; Yamashita, I1
Badia, A; Claro, E; García, A; Picatoste, F; Sallés, J1
Maura, G; Pittaluga, A; Raiteri, M; Ulivi, M1
Bockaert, J; Lafon-Cazal, M1
de Boer, TH; de Vos, CJ; Maura, G; Pinder, RM; Raiteri, M; Wieringa, J1
Kayaalp, SO; Tuncer, M; Uma, S1
Barbaz, B; Bernard, P; Braunwalder, A; Kim, HS; Liebman, JM; Lovell, RA; Robson, RD; Stone, G; Wasley, JW; Welch, J1
de Vries, JB; Dijkstra, D; Hazelhoff, B; Horn, AS; Mulder, TB; Timmermans, P; Wynberg, H1
Desai, M; Finn, BM; Gavin, T; Patt, SL; Rodebaugh, RK; Watthey, JW1
Curtis-Prior, PB; Tan, S1
Appia, F; Chariot, J; Pascaud, X; Rozé, C; Vaille, C1
Dwoskin, LP; Sparber, SB1
Ageel, AM; Alhaider, AA; Ginawi, OT1
Cai, B; Matsumoto, K; Ohta, H; Watanabe, H1
de Boer, TH; Nefkens, F; van Delft, AM; van Helvoirt, A1
Criscuolo, M; Ficarra, G; Genazzani, AR; Guo, AL; Nappi, RE; Petraglia, F; Salvestroni, C; Trentini, GP1
Marwood, JF; Okoro, EO1
Barnes, JM; Barnes, NM; Ge, J; Towers, P1
Dlaboga, D; Dziedzicka-Wasylewska, M; Maj, J; Rogoz, Z; Wrobel, A1
Imanishi, T; Inoue, T; Kakui, N; Kitamura, K; Koyama, T; Yamauchi, M; Yokoyama, F1
Barbosa-Méndez, S; Matus-Ortega, M; Salazar-Juárez, A1

Other Studies

35 other study(ies) available for mianserin and prazosin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
In vitro labeling of serotonin-S2 receptors: synthesis and binding characteristics of [3H]-7-aminoketanserin.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Frontal Lobe; Guinea Pigs; Ketanserin; Kinetics; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin

1986
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists.
    Journal of medicinal chemistry, 2003, Jan-16, Volume: 46, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Azoles; Brain; Cell Line; Cricetinae; Humans; Imidazoles; In Vitro Techniques; Indoles; Pyridines; Pyrimidines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship; Triazoles

2003
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Modification by antihypertensive drugs of amphetamine-induced stereotypy in rats.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 242, Issue:2

    Topics: Animals; Antihypertensive Agents; Behavior; Clonidine; Dextroamphetamine; Drug Interactions; Humans; Male; Mianserin; Prazosin; Rats; Stereotyped Behavior; Yohimbine

1979
Effects of MK-801 and antidepressant drugs in the forced swimming test in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1992, Volume: 2, Issue:1

    Topics: Animals; Antidepressive Agents; Citalopram; Depression; Dizocilpine Maleate; Haloperidol; Imipramine; Male; Mianserin; Motor Activity; Prazosin; Rats; Rats, Inbred Strains; Swimming

1992
Phosphoinositide hydrolysis linked 5-HT2 receptors in fibroblasts from choroid plexus.
    Brain research, 1991, Jun-28, Volume: 552, Issue:2

    Topics: Animals; Cells, Cultured; Choroid Plexus; DOM 2,5-Dimethoxy-4-Methylamphetamine; Fibroblasts; Haloperidol; Hydrolysis; Inositol Phosphates; Ketanserin; Lysergic Acid Diethylamide; Male; Mianserin; Phosphatidylinositols; Prazosin; Rabbits; Receptors, Serotonin; Serotonin; Spiperone

1991
Antidepressant drugs increase the locomotor hyperactivity induced by MK-801 in rats.
    Journal of neural transmission. General section, 1991, Volume: 85, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Citalopram; Dizocilpine Maleate; Drug Interactions; Haloperidol; Imipramine; Male; Mianserin; Motor Activity; Prazosin; Rats; Rats, Inbred Strains

1991
Neurochemical studies with the potential antipsychotic compound trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H- dibenz[2,3:6,7]oxepino[4,5-c]pyrrolidine maleate.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Autonomic Nervous System; Benzazepines; Brain Chemistry; Corpus Striatum; Cyclic AMP; Dibenzocycloheptenes; Dibenzoxepins; Heterocyclic Compounds, 4 or More Rings; In Vitro Techniques; Male; Membranes; Mianserin; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes; Yohimbine

1990
Epinephrine stimulates inositol phospholipid metabolism by activating alpha-2 adrenergic receptors in human platelets.
    Life sciences, 1989, Volume: 44, Issue:11

    Topics: Blood Platelets; Bucladesine; Cyclic GMP; Epinephrine; Humans; Inositol; Inositol Phosphates; Mianserin; Prazosin; Receptors, Adrenergic, alpha; Sugar Phosphates; Yohimbine

1989
Differential effects of chronic treatment with mianserin and protryptiline on rat brain cortical alpha 1-adrenoceptors.
    Brain research, 1989, Oct-02, Volume: 498, Issue:2

    Topics: Animals; Cerebral Cortex; Dibenzocycloheptenes; In Vitro Techniques; Male; Mianserin; Norepinephrine; Phosphatidylinositols; Prazosin; Protriptyline; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors

1989
Enhancement of endogenous GABA release from rat synaptosomal preparations is mediated by alpha 2-adrenoceptors pharmacologically different from alpha 2-autoreceptors.
    European journal of pharmacology, 1988, Nov-15, Volume: 157, Issue:1

    Topics: Animals; Clonidine; gamma-Aminobutyric Acid; Hippocampus; Male; Mianserin; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine

1988
Pharmacological characterization of octopamine-sensitive adenylate cyclase in the flight muscle of Locusta migratoria L.
    European journal of pharmacology, 1985, Dec-10, Volume: 119, Issue:1-2

    Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Catecholamines; Chlorphenamidine; Chlorpromazine; Flight, Animal; Grasshoppers; In Vitro Techniques; Male; Metoclopramide; Mianserin; Muscles; Octopamine; Phentolamine; Prazosin; Receptors, Adrenergic; Receptors, Biogenic Amine; Serotonin; Synephrine; Tyramine

1985
Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, Org 3770 and its enantiomers.
    Neuropharmacology, 1988, Volume: 27, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Autonomic Nervous System; Binding, Competitive; Cerebral Cortex; Corpus Striatum; In Vitro Techniques; Male; Mianserin; Mirtazapine; Norepinephrine; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Stereoisomerism; Synaptosomes; Yohimbine

1988
The subtype of serotonin (5-HT) receptors in the rat pulmonary artery.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 288, Issue:2

    Topics: Animals; Female; In Vitro Techniques; Ketanserin; Male; Methysergide; Mianserin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Pizotyline; Prazosin; Pulmonary Artery; Rats; Receptors, Serotonin

1987
CGS 7525A, a new, centrally active alpha 2 adrenoceptor antagonist.
    Life sciences, 1983, Jan-24, Volume: 32, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Benzodiazepines; Chemical Phenomena; Chemistry; Clonidine; Male; Mesencephalon; Mianserin; Norepinephrine; Prazosin; Quinones; Rats; Rats, Inbred Strains; Spiperone; Yohimbine

1983
The hydroxy-hexanydronaphthoxazines: a new group of very potent and selective dopamine agonists.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:9

    Topics: 4-Butyrolactone; Animals; Binding, Competitive; Brain Chemistry; Chemical Phenomena; Chemistry; Clonidine; Dopamine; Ergolines; Homovanillic Acid; Humans; In Vitro Techniques; Mianserin; Oxazines; Prazosin; Rats; Receptors, Adrenergic; Receptors, Serotonin; Stereotyped Behavior

1984
Synthesis and biological properties of thiophene ring analogues of mianserin.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:8

    Topics: Animals; Brain; Dibenzazepines; Histamine Release; Mianserin; Mice; Prazosin

1983
Comparative effects of RX 781094, mianserin, yohimbine, rauwolscine and prazosin in reversing clonidine inhibition of MIX-stimulated lipolysis in hamster isolated white fat cells.
    Pharmacological research communications, 1984, Volume: 16, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Dioxanes; Epididymis; Idazoxan; In Vitro Techniques; Lipolysis; Male; Mianserin; Prazosin; Theophylline; Yohimbine

1984
Clonidine inhibition of pancreatic secretion in rats: a possible central site of action.
    European journal of pharmacology, 1981, Dec-17, Volume: 76, Issue:4

    Topics: Animals; Clonidine; Deoxyglucose; Gastric Juice; Male; Mianserin; Pancreas; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1981
Comparison of yohimbine, mianserin, chlorpromazine and prazosin as antagonists of the suppressant effect of clonidine on operant behavior.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Animals; Behavior, Animal; Chlorpromazine; Clonidine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Male; Mianserin; Prazosin; Rats; Rats, Inbred Strains; Yohimbine

1983
The quipazine- and TFMPP-increased conditioned avoidance response in rats: role of 5HT1C/5-HT2 receptors.
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: Animals; Avoidance Learning; Conditioning, Operant; Ketanserin; Male; Mianserin; Nadolol; Pindolol; Piperazines; Prazosin; Quipazine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reference Values; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Tropanes

1993
Biphasic effects of typical antidepressants and mianserin, an atypical antidepressant, on aggressive behavior in socially isolated mice.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:3

    Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Clomipramine; Male; Maprotiline; Mianserin; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Selective Serotonin Reuptake Inhibitors; Social Isolation; Yohimbine

1993
Differences in modulation of noradrenergic and serotonergic transmission by the alpha-2 adrenoceptor antagonists, mirtazapine, mianserin and idazoxan.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Corpus Striatum; Dioxanes; Hippocampus; Idazoxan; Imidazoles; Male; Mianserin; Mirtazapine; Norepinephrine; Prazosin; Rats; Rats, Wistar; Serotonin; Tetrodotoxin

1996
Adrenergic and serotoninergic receptors mediate the immunological activation of corticosterone secretion in male rats.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1996, Volume: 10, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Corticosterone; Immune System; Lipopolysaccharides; Male; Mianserin; Pindolol; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Serotonin; Serotonin Antagonists

1996
Effects of 5HT2 receptor antagonists on responses to potassium depolarization in rat isolated aorta.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:1

    Topics: Animals; Aorta, Thoracic; Cinnarizine; Cyproheptadine; Diltiazem; Drug Synergism; Felodipine; Female; In Vitro Techniques; Ketanserin; Male; Mianserin; Muscle Contraction; Nifedipine; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reproducibility of Results; Ritanserin; Serotonin Antagonists; Verapamil

1997
Distribution of S(-)-zacopride-insensitive [125I]R(+)-zacopride binding sites in the rat brain and peripheral tissues.
    European journal of pharmacology, 1997, Aug-13, Volume: 332, Issue:3

    Topics: Animals; Autoradiography; Benzamides; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; In Vitro Techniques; Iodine Radioisotopes; Male; Mianserin; Prazosin; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Stereoisomerism; Sulpiride; Tissue Distribution

1997
Effect of repeated treatment with mirtazapine on the central alpha1-adrenergic receptors.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2002, Volume: 53, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aggression; Animals; Antidepressive Agents, Tricyclic; Binding, Competitive; Cerebral Cortex; Exploratory Behavior; Male; Methoxamine; Mianserin; Mice; Mirtazapine; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1

2002
Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and alpha1-adrenergic receptor.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 92, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Conditioning, Classical; Fear; Male; Mianserin; Mirtazapine; Prazosin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-1

2009
Synergistic interactions between mirtazapine and prazosin prevent the induction and expression of behavioral sensitization to cocaine in rats.
    Physiology & behavior, 2017, Oct-15, Volume: 180

    Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Locomotion; Male; Mianserin; Mirtazapine; Prazosin; Rats; Rats, Wistar

2017