mianserin and metergoline

mianserin has been researched along with metergoline in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199014 (48.28)18.7374
1990's11 (37.93)18.2507
2000's3 (10.34)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glennon, RA1
Andrews, PR; Craik, DJ; Martin, JL1
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Amlaiky, N; Hen, R; Plassat, JL1
Arrang, JM; Diaz, J; Leurs, R; Ruat, M; Schwartz, JC; Tardivel-Lacombe, J; Traiffort, E1
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR1
Boess, FG; Meyer, V; Monsma, FJ; Sleight, AJ; Zwingelstein, C1
Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP1
Bentley, J; Boess, FG; Bös, M; Bourson, A; Riemer, C; Sleight, AJ1
Benhamú, B; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Porras, E; Ramos, JA1
Benhamú, B; Campillo, M; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Olivella, M; Pardo, L; Porras, E; Ramos, JA; Soto, LJ1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Aulakh, CS; Hill, JL; Murphy, DL1
Bennett, GW; Lighton, C; Marsden, CA1
Chojnacka-Wójcik, E; Jaros, T; Kłodzińska, A; Maj, J1
Hole, DR; Hunter, AJ; Wilson, CA1
Trulson, ME1
Fuller, RW; Snoddy, HD1
Berge, OG1
Cella, SG; Mantegazza, P; Morgese, M; Müller, EE; Picotti, GB1
Invernizzi, R; Samanin, R; Spampinato, U1
Jones, RS1
Berge, OG; Fasmer, OB; Hole, K1
Heym, J; Jacobs, BL; Rasmussen, K1
Broekkamp, CL; Garrigou, D; LLoyd, KG1
Ghazi-Khansari, M; Rezayat, M; Sajedian, M; Zarrindast, MR1

Reviews

1 review(s) available for mianserin and metergoline

ArticleYear
Central serotonin receptors as targets for drug research.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin

1987

Other Studies

28 other study(ies) available for mianserin and metergoline

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Sep-15, Volume: 90, Issue:18

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; CHO Cells; Cricetinae; Cyclic AMP; DNA; Genomic Library; Kinetics; Lysergic Acid Diethylamide; Mianserin; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Rats; Receptors, Serotonin; Restriction Mapping; Serotonin; Serotonin Receptor Agonists; Transfection

1993
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature

1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity

1996
Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor.
    Molecular pharmacology, 1997, Volume: 52, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cloning, Molecular; Cricetinae; Dogs; Drug Interactions; Ergolines; Guinea Pigs; Humans; Kidney; Ligands; Lysergic Acid Diethylamide; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin; Threonine; Tryptamines

1997
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
    British journal of pharmacology, 1997, Volume: 122, Issue:1

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid

1997
The 5-hydroxytryptamine6 receptor-selective radioligand [3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum.
    Molecular pharmacology, 1998, Volume: 54, Issue:3

    Topics: Aminopyridines; Animals; Binding Sites; Corpus Striatum; HeLa Cells; Humans; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Swine; Tritium

1998
First pharmacophoric hypothesis for 5-HT7 antagonism.
    Bioorganic & medicinal chemistry letters, 2000, May-15, Volume: 10, Issue:10

    Topics: Animals; Cell Membrane; Drug Design; Drug Evaluation, Preclinical; Hypothalamus; Models, Molecular; Rats; Receptors, Serotonin; Reproducibility of Results; Serotonin Antagonists; Structure-Activity Relationship

2000
Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.
    Journal of medicinal chemistry, 2003, Dec-18, Volume: 46, Issue:26

    Topics: Animals; Binding, Competitive; Computer Simulation; Drug Design; Hypothalamus; In Vitro Techniques; Lactams; Ligands; Male; Models, Molecular; Molecular Conformation; Naphthalenes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides; Thiazoles

2003
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Effects of various serotonin receptor subtype-selective antagonists alone and on m-chlorophenylpiperazine-induced neuroendocrine changes in rats.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2

    Topics: Animals; Corticosterone; Ergolines; Male; Metergoline; Mianserin; Neurosecretory Systems; Piperazines; Prolactin; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone

1992
Increase in levels and ex vivo release of thyrotrophin-releasing hormone (TRH) in specific regions of the CNS of the rat by chronic treatment with antidepressants.
    Neuropharmacology, 1985, Volume: 24, Issue:5

    Topics: Amitriptyline; Animals; Antidepressive Agents; Central Nervous System; Clomipramine; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Metergoline; Mianserin; Rats; Rats, Inbred Strains; Serotonin; Thyrotropin-Releasing Hormone

1985
Exploratory hypoactivity induced by m-trifluoromethylphenylpiperazine (TFMPP) and m-chlorophenylpiperazine (m-CPP).
    Journal of neural transmission. Parkinson's disease and dementia section, 1989, Volume: 1, Issue:3

    Topics: Animals; Ergolines; Exploratory Behavior; Male; Metergoline; Mianserin; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone

1989
Studies into the dual effects of serotonergic pharmacological agents on female sexual behaviour in the rat: preliminary evidence that endogenous 5HT is stimulatory.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:1

    Topics: 5-Hydroxytryptophan; Adrenalectomy; Alanine; Animals; Castration; Cinanserin; Female; Ketanserin; Metergoline; Methysergide; Mianserin; Piperidines; Progesterone; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Sexual Behavior, Animal; Zimeldine

1985
Dissociations between the effects of hallucinogens on behavior and raphe unit activity in behaving cats.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:2

    Topics: Animals; Apomorphine; Behavior, Animal; Cats; Chlorpromazine; Dextroamphetamine; Electroencephalography; Electromyography; Electrooculography; Electrophysiology; Female; Hallucinogens; Haloperidol; Male; Metergoline; Mianserin; Neurons; Raphe Nuclei; Receptors, Serotonin; Serotonin Antagonists

1986
Elevation of serum corticosterone concentrations in rats by pergolide and other dopamine agonists.
    Endocrinology, 1981, Volume: 109, Issue:4

    Topics: Animals; Antiparkinson Agents; Corticosterone; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Ergolines; Haloperidol; Male; Metergoline; Mianserin; Pergolide; Rats; Rats, Inbred Strains; Spiperone

1981
Effects of 5-HT receptor agonists and antagonists on a reflex response to radiant heat in normal and spinally transected rats.
    Pain, 1982, Volume: 13, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Circadian Rhythm; Hot Temperature; Male; Metergoline; Methiothepin; Mianserin; Neurotransmitter Agents; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Serotonin; Serotonin Antagonists; Spinal Cord

1982
Presynaptic alpha 2 -adrenergic stimulation leads to growth hormone release in the dog.
    Life sciences, 1984, Jan-30, Volume: 34, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Clemastine; Clonidine; Dogs; Drug Interactions; Female; Growth Hormone; Male; Metergoline; Mianserin; Synapses; Triazoles; Yohimbine

1984
Evidence of serotonin involvement in the effect of morphine on dopamine metabolism in the rat nucleus accumbens but not in the striatum.
    Pharmacological research communications, 1984, Volume: 16, Issue:5

    Topics: Animals; Corpus Striatum; Dopamine; Fenclonine; Homovanillic Acid; Male; Metergoline; Mianserin; Morphine; Nucleus Accumbens; Rats; Septal Nuclei; Serotonin; Serotonin Antagonists

1984
Responses of cortical neurones to stimulation of the nucleus raphé medianus: a pharmacological analysis of the role of indoleamines.
    Neuropharmacology, 1982, Volume: 21, Issue:6

    Topics: 5,7-Dihydroxytryptamine; Animals; Brain Stem; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Fenclonine; Male; Metergoline; Methysergide; Mianserin; Neural Inhibition; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Synaptic Transmission; Tryptamines

1982
Serotonin receptor antagonists induce hyperalgesia without preventing morphine antinociception.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:5

    Topics: Analgesics; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Male; Metergoline; Mianserin; Morphine; Naloxone; Nociceptors; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Serotonin

1983
Some behavioral effects of hallucinogens are mediated by a postsynaptic serotonergic action: evidence from single unit studies in freely moving cats.
    European journal of pharmacology, 1984, May-18, Volume: 101, Issue:1-2

    Topics: Animals; Apomorphine; Behavior, Animal; Cats; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Female; Hallucinogens; Ketanserin; Lisuride; Lysergic Acid Diethylamide; Metergoline; Mianserin; Piperidines; Receptors, Serotonin; Serotonin Antagonists; Synapses

1984
Serotonin-mimetic and antidepressant drugs on passive avoidance learning by olfactory bulbectomised rats.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13, Issue:5

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Clonidine; Ergolines; Fenfluramine; Fluoxetine; Imipramine; Male; Metergoline; Mianserin; Olfactory Bulb; Quipazine; Rats; Serotonin; Serotonin Antagonists

1980
Effects of 5-HT receptor antagonists on morphine-induced tolerance in mice.
    European journal of pharmacology, 1995, Feb-06, Volume: 273, Issue:3

    Topics: Analgesics; Animals; Delayed-Action Preparations; Drug Tolerance; Injections, Subcutaneous; Male; Metergoline; Methysergide; Mianserin; Mice; Morphine; Pain Measurement; Ritanserin; Serotonin Antagonists

1995