mianserin and mesulergine

mianserin has been researched along with mesulergine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.29)18.7374
1990's20 (57.14)18.2507
2000's9 (25.71)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glennon, RA1
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Amlaiky, N; Hen, R; Plassat, JL1
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR1
Egan, C; Herrick-Davis, K; Teitler, M1
Boess, FG; Meyer, V; Monsma, FJ; Sleight, AJ; Zwingelstein, C1
Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP1
Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB1
Bentley, J; Boess, FG; Bös, M; Bourson, A; Riemer, C; Sleight, AJ1
Benhamú, B; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Porras, E; Ramos, JA1
Andersen, K; Balle, T; Larsen, AK; Liljefors, T; Perregaard, J; Ramirez, MT; Søby, KK1
Benhamú, B; Campillo, M; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Olivella, M; Pardo, L; Porras, E; Ramos, JA; Soto, LJ1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D1
Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R1
Esterle, TM; Sanders-Bush, E1
Aulakh, CS; Hill, JL; Murphy, DL1
Chojnacka-Wójcik, E; Jaros, T; Kłodzińska, A; Maj, J1
Curzon, G; Kennett, GA1
Palacios, JM; Pazos, A; Probst, A1
Markstein, R; Palacios, JM; Pazos, A1
Barker, EL; Sanders-Bush, E; Schmidt, D; Westphal, RS1
Gregory, CM; Pranzatelli, MR1
Di Scala, G; Hoyer, D; Rigo, M; Rocha, B; Sandner, G1
Akiyoshi, J; Fujii, I; Isogawa, K; Nagayama, H; Yamada, K1
Hartman, JL; Northup, JK1
Elliott, JM; Newton, RA1
Boess, FG; Bourson, A; Kapps, V; Rudler, A; Sleight, AJ; Zwingelstein, C1
Grinde, E; Herrick-Davis, K; Niswender, CM1
Ebersole, BJ; Rosendorff, A; Sealfon, SC1
Clifton, PG; Dourish, CT; Kennett, GA; Lee, MD; Somerville, EM1
Christopoulos, A; Devlin, MG; Guida, E; Ryan, OM; Sexton, PM; Smith, NJ1
Ackley, DC; Holbert, JK; Hu, XE; Kim, N; Klopfenstein, SR; Méndez-Andino, JL; Meyers, KM; Mitchell, MC; Mittelstadt, SW; Mumin, RN; Paris, JL; Reizes, O; Wos, JA1
Haleem, DJ; Shireen, E1

Reviews

1 review(s) available for mianserin and mesulergine

ArticleYear
Central serotonin receptors as targets for drug research.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin

1987

Other Studies

34 other study(ies) available for mianserin and mesulergine

ArticleYear
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature

1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity

1996
Activating mutations of the serotonin 5-HT2C receptor.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: Animals; Binding Sites; COS Cells; Ergolines; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Lysine; Methysergide; Mianserin; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylinositols; Point Mutation; Protein Conformation; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serine; Serotonin; Serotonin Antagonists; Signal Transduction; Transfection

1997
Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor.
    Molecular pharmacology, 1997, Volume: 52, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cloning, Molecular; Cricetinae; Dogs; Drug Interactions; Ergolines; Guinea Pigs; Humans; Kidney; Ligands; Lysergic Acid Diethylamide; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin; Threonine; Tryptamines

1997
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
    British journal of pharmacology, 1997, Volume: 122, Issue:1

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid

1997
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1

    Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine

1998
The 5-hydroxytryptamine6 receptor-selective radioligand [3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum.
    Molecular pharmacology, 1998, Volume: 54, Issue:3

    Topics: Aminopyridines; Animals; Binding Sites; Corpus Striatum; HeLa Cells; Humans; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Swine; Tritium

1998
First pharmacophoric hypothesis for 5-HT7 antagonism.
    Bioorganic & medicinal chemistry letters, 2000, May-15, Volume: 10, Issue:10

    Topics: Animals; Cell Membrane; Drug Design; Drug Evaluation, Preclinical; Hypothalamus; Models, Molecular; Rats; Receptors, Serotonin; Reproducibility of Results; Serotonin Antagonists; Structure-Activity Relationship

2000
Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists.
    Journal of medicinal chemistry, 2003, Jan-16, Volume: 46, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Azoles; Brain; Cell Line; Cricetinae; Humans; Imidazoles; In Vitro Techniques; Indoles; Pyridines; Pyrimidines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship; Triazoles

2003
Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.
    Journal of medicinal chemistry, 2003, Dec-18, Volume: 46, Issue:26

    Topics: Animals; Binding, Competitive; Computer Simulation; Drug Design; Hypothalamus; In Vitro Techniques; Lactams; Ligands; Male; Models, Molecular; Molecular Conformation; Naphthalenes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides; Thiazoles

2003
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004
Physical binding pocket induction for affinity prediction.
    Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19

    Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A

2009
Serotonin agonists increase transferrin levels via activation of 5-HT1C receptors in choroid plexus epithelium.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:12

    Topics: Amino Acid Isomerases; Animals; Blotting, Northern; Carrier Proteins; Cells, Cultured; Choroid Plexus; Cyclosporins; Epithelium; Ergolines; Fibroblasts; Kinetics; Male; Mianserin; Peptidylprolyl Isomerase; Phosphatidylinositols; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; RNA Probes; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Thymidine; Time Factors; Transferrin

1992
Effects of various serotonin receptor subtype-selective antagonists alone and on m-chlorophenylpiperazine-induced neuroendocrine changes in rats.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2

    Topics: Animals; Corticosterone; Ergolines; Male; Metergoline; Mianserin; Neurosecretory Systems; Piperazines; Prolactin; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiperone

1992
Exploratory hypoactivity induced by m-trifluoromethylphenylpiperazine (TFMPP) and m-chlorophenylpiperazine (m-CPP).
    Journal of neural transmission. Parkinson's disease and dementia section, 1989, Volume: 1, Issue:3

    Topics: Animals; Ergolines; Exploratory Behavior; Male; Metergoline; Mianserin; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone

1989
Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors.
    Psychopharmacology, 1988, Volume: 96, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Ergolines; Feeding Behavior; Food Deprivation; Indoles; Male; Mianserin; Motor Activity; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tropisetron

1988
Serotonin receptors in the human brain--III. Autoradiographic mapping of serotonin-1 receptors.
    Neuroscience, 1987, Volume: 21, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Aged; Aged, 80 and over; Autoradiography; Brain; Ergolines; Female; Humans; Male; Mianserin; Middle Aged; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1987
Serotonin-1C sites in the choroid plexus are not linked in a stimulatory or inhibitory way to adenylate cyclase.
    Brain research, 1986, Aug-13, Volume: 380, Issue:1

    Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cerebral Cortex; Choroid Plexus; Colforsin; Cyclic AMP; Dopamine; Ergolines; Hippocampus; Histamine; Kinetics; Mianserin; Rats; Receptors, Serotonin; Serotonin; Swine

1986
Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands.
    The Journal of biological chemistry, 1994, Apr-22, Volume: 269, Issue:16

    Topics: 3T3 Cells; Animals; Antiparkinson Agents; Cell Membrane; Cells, Cultured; Choroid Plexus; Cloning, Molecular; DNA, Complementary; DOM 2,5-Dimethoxy-4-Methylamphetamine; Epithelium; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Lysergic Acid Diethylamide; Mianserin; Mice; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Transfection

1994
High and low affinity 5-HT2 and 5-HT1C binding sites: responses to neonatal 5,7-DHT lesions in rat brain.
    Cytobios, 1993, Volume: 75, Issue:302-303

    Topics: 5,7-Dihydroxytryptamine; Analysis of Variance; Animals; Animals, Newborn; Binding Sites; Brain Neoplasms; Brain Stem; Cerebellum; Cerebral Cortex; Diencephalon; Dose-Response Relationship, Drug; Ergolines; Female; Hippocampus; Injections, Intraperitoneal; Mianserin; Pregnancy; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin; Time Factors; Tritium

1993
Effect of 5,7-dihydroxytryptamine lesion on mianserin-induced conditioned place aversion and on 5-hydroxytryptamine1C receptors in the rat brain.
    Neuroscience, 1993, Volume: 56, Issue:3

    Topics: 5,7-Dihydroxytryptamine; Animals; Antiparkinson Agents; Autoradiography; Brain Chemistry; Carbolines; Conditioning, Operant; Ergolines; In Situ Hybridization; Male; Mianserin; Rats; Receptors, GABA-A; Receptors, Serotonin; RNA, Messenger; Transcription, Genetic

1993
Effects of antidepressants on intracellular Ca2+ mobilization in CHO cells transfected with the human 5-HT2C receptors.
    Biological psychiatry, 1996, Jun-15, Volume: 39, Issue:12

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Calcium; Calcium Channels; CHO Cells; Cricetinae; Ergolines; Humans; Intracellular Fluid; Mianserin; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Transfection

1996
Functional reconstitution in situ of 5-hydroxytryptamine2c (5HT2c) receptors with alphaq and inverse agonism of 5HT2c receptor antagonists.
    The Journal of biological chemistry, 1996, Sep-13, Volume: 271, Issue:37

    Topics: Animals; Binding, Competitive; Cattle; Cell Line; Decapodiformes; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Ketanserin; Mianserin; Photoreceptor Cells, Invertebrate; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Cell Surface; Receptors, Serotonin; Recombinant Proteins; Serotonin

1996
Mianserin-induced down-regulation of human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors stably expressed in the human neuroblastoma cell line SH-SY5Y.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: Cell Membrane; DNA, Complementary; Down-Regulation; Ergolines; Humans; Ketanserin; Kinetics; Mianserin; Neuroblastoma; Phosphatidylinositols; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serotonin; Time Factors; Transfection; Tumor Cells, Cultured

1997
Correlation between 5-HT7 receptor affinity and protection against sound-induced seizures in DBA/2J mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:6

    Topics: Acoustic Stimulation; Animals; Anticonvulsants; CHO Cells; Cricetinae; Ergolines; Male; Methysergide; Mianserin; Mice; Mice, Inbred DBA; Receptors, Serotonin; Seizures; Serotonin Antagonists

1997
Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction.
    Journal of neurochemistry, 1999, Volume: 73, Issue:4

    Topics: Animals; COS Cells; Ergolines; Humans; Inositol Phosphates; Kinetics; Mianserin; Mutagenesis, Site-Directed; Pargyline; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; RNA Editing; Serotonin; Serotonin Antagonists; Signal Transduction; Transfection

1999
Conserved helix 7 tyrosine functions as an activation relay in the serotonin 5HT(2C) receptor.
    Brain research. Molecular brain research, 2000, Dec-08, Volume: 84, Issue:1-2

    Topics: Amino Acid Motifs; Amphetamines; Binding, Competitive; Cell Line; Conserved Sequence; Ergolines; Humans; Indoles; Inositol Phosphates; Ligands; Mianserin; Mutation; Protein Structure, Secondary; Pyridines; Quipazine; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection; Tyrosine

2000
Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor agonist mCPP in 5-HT1B receptor knockout mice.
    Psychopharmacology, 2004, Volume: 176, Issue:1

    Topics: Animals; Binding Sites; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Eating; Ergolines; Fenfluramine; Genotype; Injections, Intraperitoneal; Injections, Subcutaneous; Isomerism; Mianserin; Mice; Mice, Knockout; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Satiation; Satiety Response; Serotonin 5-HT2 Receptor Agonists; Species Specificity; Spiperone; Spiro Compounds; Time Factors; Tritium; United Kingdom

2004
Regulation of serotonin 5-HT2C receptors by chronic ligand exposure.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: Algorithms; Analysis of Variance; Animals; Binding, Competitive; Cell Membrane; Chlorpromazine; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Ergolines; Humans; Indoles; Indophenol; Inositol Phosphates; Kinetics; Ligands; Lisuride; Mianserin; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium; Tryptamines

2004
Aminomethyl tetrahydronaphthalene biphenyl carboxamide MCH-R1 antagonists--Increasing selectivity over hERG.
    Bioorganic & medicinal chemistry letters, 2007, Feb-01, Volume: 17, Issue:3

    Topics: Biphenyl Compounds; ERG1 Potassium Channel; Ergolines; Ether-A-Go-Go Potassium Channels; Humans; Indicators and Reagents; Mianserin; Naphthalenes; Potassium Channel Blockers; Receptor, Serotonin, 5-HT2C; Receptors, Somatostatin; Serotonin Antagonists; Structure-Activity Relationship

2007
Reversal of haloperidol-induced motor deficits by mianserin and mesulergine in rats.
    Pakistan journal of pharmaceutical sciences, 2011, Volume: 24, Issue:1

    Topics: Animals; Antipsychotic Agents; Catalepsy; Dopamine Agonists; Dyskinesia, Drug-Induced; Ergolines; Haloperidol; Male; Mianserin; Motor Activity; Parkinson Disease, Secondary; Psychomotor Performance; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors

2011