mianserin has been researched along with demethylmirtazapine in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 13 (54.17) | 29.6817 |
| 2010's | 9 (37.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Dingler, E; Maris, FA; Niehues, S | 1 |
| Greenblatt, DJ; Shader, RI; Störmer, E; von Moltke, LL | 1 |
| Härtter, S; Hiemke, C; Shams, M | 1 |
| Brockmöller, J; Kress, I; Meineke, I; Poser, W; Rüther, E | 1 |
| Baumann, P; Cochard, N; Eap, CB; Jonzier-Perey, M; Paus, E | 1 |
| Ahlner, J; Bengtsson, F; Prochazka, J; Reis, M; Sitsen, A | 1 |
| Aderjan, R; Mattern, R; Pedal, I; Skopp, G; Wenzel, S | 1 |
| Hackett, LP; Ilett, KF; Kohan, R; Kristensen, JH; Rampono, J | 1 |
| Brockmöller, J; Kirchheiner, J; Meineke, I; Steinmetz, H | 1 |
| Baumann, P; Jonzier-Perey, M; Nikisch, G; Paus, E | 1 |
| Aturki, Z; D'Orazio, G; Fanali, S; Raggi, MA; Rocco, A; Scotti, V | 1 |
| Bonato, PS; de Santana, FJ; Lanchote, VL | 1 |
| Hiemke, C; Kircher, T; Leube, D; Milenovic, S; Schlotterbeck, PM; Vehren, T | 1 |
| Ahlner, J; Baumann, P; Bengtsson, F; Dahl, ML; Jonzier-Perey, M; Lind, AB; Powell Golay, K; Reis, M | 1 |
| Bonato, PS; Cesarino, EJ; de Santana, FJ; Jabor, VA; Lanchote, VL | 1 |
| Kumar, KN; Ramakrishna, S; Rao, RN | 1 |
| Giorgi, M; Yun, H | 1 |
| Cao, WQ; Fan, GR; Gao, FY; Li, J; Wen, J; Yang, N; Zhang, WT | 1 |
| Groppe, SE; Gründer, G; Hiemke, C; Paulzen, M; Tauber, SC; Veselinovic, T | 1 |
| Akiyama, K; Aoki, A; Hayashi, Y; Inoue, Y; Ishiguro, S; Kato, K; Shimoda, K; Tsuchimine, S; Ueda, M; Watanabe, T; Yasui-Furukori, N | 1 |
| Aghamohammadhasani, M; Chamsaz, M; Ghorbani, M; Lahoori, NA; Rounaghi, GH; Seyedin, O | 1 |
| Avato, FM; Brandolini, F; Gaudio, RM; Groppi, A; Morini, L; Talarico, A; Vignali, C | 1 |
| Akiyama, K; Hayashi, Y; Inoue, Y; Kato, K; Komahashi-Sasaki, H; Ozeki, Y; Pierce, J; Sasaki, T; Shimoda, K; Shinozaki, M; Tsuchimine, S; Watanabe, T; Yasui-Furukori, N | 1 |
| Ameline, A; Kintz, P; Raul, JS | 1 |
3 trial(s) available for mianserin and demethylmirtazapine
| Article | Year |
|---|---|
High-performance liquid chromatographic assay with fluorescence detection for the routine monitoring of the antidepressant mirtazapine and its demethyl metabolite in human plasma.
Topics: Antidepressive Agents, Tricyclic; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Humans; Indicators and Reagents; Mianserin; Mirtazapine; Quality Control; Reference Standards; Reproducibility of Results; Solvents; Spectrometry, Fluorescence | 1999 |
Chirality in the new generation of antidepressants: stereoselective analysis of the enantiomers of mirtazapine, N-demethylmirtazapine, and 8-hydroxymirtazapine by LC-MS.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Chromatography, Liquid; Female; Humans; Male; Mass Spectrometry; Mianserin; Middle Aged; Mirtazapine; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism | 2004 |
Inter- and intraindividual pharmacokinetic variations of mirtazapine and its N-demethyl metabolite in patients treated for major depressive disorder: a 6-month therapeutic drug monitoring study.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Body Size; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Diazepam; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Mianserin; Mirtazapine; Outpatients; Oxazepam; Prospective Studies; Sex Factors; Smoking; Time Factors; Treatment Refusal | 2005 |
21 other study(ies) available for mianserin and demethylmirtazapine
| Article | Year |
|---|---|
Metabolism of the antidepressant mirtazapine in vitro: contribution of cytochromes P-450 1A2, 2D6, and 3A4.
Topics: Antidepressive Agents, Tricyclic; Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydroxylation; Isoenzymes; Methylation; Mianserin; Microsomes, Liver; Mirtazapine; Oxidation-Reduction; Quinidine; Recombinant Proteins | 2000 |
Therapeutic drug monitoring of the antidepressant mirtazapine and its N-demethylated metabolite in human serum.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Histamine H1 Antagonists; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Sensitivity and Specificity | 2004 |
Therapeutic drug monitoring of mirtazapine and its metabolite desmethylmirtazapine by HPLC with fluorescence detection.
Topics: Adrenergic alpha-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Sensitivity and Specificity; Spectrometry, Fluorescence | 2004 |
Tissue distribution of mirtazapine and desmethylmirtazapine in a case of mirtazapine poisoning.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bile; Brain Chemistry; Forensic Pathology; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Humans; Kidney; Liver; Lung; Male; Mianserin; Mirtazapine; Muscle, Skeletal; Nortriptyline; Sertraline; Suicide; Tissue Distribution | 2006 |
Transfer of the antidepressant mirtazapine into breast milk.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Breast Feeding; Depression, Postpartum; Female; Humans; Infant; Infant, Newborn; Mianserin; Milk, Human; Mirtazapine; Pregnancy | 2007 |
Therapeutic drug monitoring of mirtazapine, desmethylmirtazapine, 8-hydroxymirtazapine, and mirtazapine-N-oxide by enantioselective HPLC with fluorescence detection.
Topics: Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Drug Monitoring; Fluorescence; Humans; Male; Mianserin; Mirtazapine; Quality Control; Stereoisomerism | 2006 |
Mirtazapine enantiomers in blood and cerebrospinal fluid.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Administration Schedule; Humans; Male; Mianserin; Mirtazapine; Severity of Illness Index; Stereoisomerism | 2006 |
Enantioselective separation of the novel antidepressant mirtazapine and its main metabolites by CEC.
Topics: Antidepressive Agents; Capillary Electrochromatography; Humans; Mianserin; Mirtazapine; Stereoisomerism; Vancomycin | 2007 |
Capillary electrophoretic chiral determination of mirtazapine and its main metabolites in human urine after enzymatic hydrolysis.
Topics: Electrophoresis, Capillary; Humans; Hydrolysis; Mianserin; Mirtazapine; Temperature | 2008 |
No influence of dialysis on mirtazapine - a case report.
Topics: Adult; Antidepressive Agents, Tricyclic; Biotransformation; Depressive Disorder; Dialysis Solutions; Female; Humans; Mianserin; Mirtazapine; Renal Dialysis; Renal Insufficiency | 2008 |
Steady-state concentrations of mirtazapine, N-desmethylmirtazapine, 8-hydroxymirtazapine and their enantiomers in relation to cytochrome P450 2D6 genotype, age and smoking behaviour.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Female; Genotype; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Prospective Studies; Smoking; Stereoisomerism | 2009 |
Enantioselective analysis of mirtazapine, demethylmirtazapine and 8-hydroxy mirtazapine in human urine after solid-phase microextraction.
Topics: Antidepressive Agents, Tricyclic; Buffers; Chromatography, Liquid; Humans; Hydrogen-Ion Concentration; Mianserin; Mirtazapine; Osmolar Concentration; Reproducibility of Results; Solid Phase Microextraction; Stereoisomerism; Tandem Mass Spectrometry | 2010 |
Enantiomeric separation of mirtazapine and its metabolite in rat plasma by reverse polar ionic liquid chromatography using fluorescence and polarimetric detectors connected in series.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Linear Models; Mianserin; Mirtazapine; Rats; Rats, Wistar; Reproducibility of Results; Spectrometry, Fluorescence; Stereoisomerism | 2011 |
Pharmacokinetics of mirtazapine and its main metabolites in Beagle dogs: a pilot study.
Topics: Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Dogs; Half-Life; Male; Metabolic Clearance Rate; Mianserin; Mirtazapine; Pilot Projects | 2012 |
Enantioselective separation of mirtazapine and its metabolites by capillary electrophoresis with acetonitrile field-amplified sample stacking and its application.
Topics: Acetonitriles; Administration, Oral; Antidepressive Agents, Tricyclic; beta-Cyclodextrins; Biotransformation; Buffers; Chemical Fractionation; Cyclic N-Oxides; Electrophoresis, Capillary; Humans; Limit of Detection; Male; Mianserin; Mirtazapine; Reproducibility of Results; Stereoisomerism | 2014 |
Distribution pattern of mirtazapine and normirtazapine in blood and CSF.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Blood-Brain Barrier; Female; Humans; Male; Mental Disorders; Mianserin; Middle Aged; Mirtazapine | 2015 |
Factors Affecting Steady-state Plasma Concentrations of Enantiomeric Mirtazapine and its Desmethylated Metabolites in Japanese Psychiatric Patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Antidepressive Agents, Tricyclic; Cytochrome P-450 CYP2D6; Depressive Disorder; Female; Genotype; Humans; Japan; Male; Mianserin; Middle Aged; Mirtazapine; Pharmacogenetics; Young Adult | 2015 |
Development of a novel ultrasonic-assisted magnetic dispersive solid-phase microextraction method coupled with high performance liquid chromatography for determination of mirtazapine and its metabolites in human urine and water samples employing experimen
Topics: Adsorption; Aniline Compounds; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Factor Analysis, Statistical; Fresh Water; Graphite; Healthy Volunteers; Humans; Magnets; Mianserin; Mirtazapine; Nanocomposites; Oxides; Solid Phase Microextraction; Sonication; Water Pollutants, Chemical | 2016 |
Mirtazapine fatal poisoning.
Topics: Antidepressive Agents, Tricyclic; Chromatography, Liquid; Humans; Male; Mass Spectrometry; Mianserin; Middle Aged; Mirtazapine; Suicide | 2017 |
8-Hydroxylation and Glucuronidation of Mirtazapine in Japanese Psychiatric Patients: Significance of the Glucuronidation Pathway of 8-Hydroxy-Mirtazapine.
Topics: Age Factors; Alleles; Anti-Anxiety Agents; Asian People; Cytochrome P-450 CYP2D6; Genotype; Glucuronides; Humans; Hydroxylation; Japan; Mental Disorders; Mianserin; Mirtazapine; Smoking | 2019 |
Evidence of repeated mirtazapine poisoning in children by hair analysis.
Topics: Antidepressive Agents; Child; Child Abuse; Chromatography, Liquid; Forensic Toxicology; Hair; Humans; Mass Spectrometry; Mianserin; Mirtazapine | 2021 |