mianserin and clozapine

mianserin has been researched along with clozapine in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (8.00)	18.7374
1990's	13 (26.00)	18.2507
2000's	21 (42.00)	29.6817
2010's	12 (24.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B	1
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP	1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR	1
Amlaiky, N; Hen, R; Plassat, JL	1
Arrang, JM; Diaz, J; Leurs, R; Ruat, M; Schwartz, JC; Tardivel-Lacombe, J; Traiffort, E	1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR	1
Boess, FG; Meyer, V; Monsma, FJ; Sleight, AJ; Zwingelstein, C	1
Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB	1
Egan, CT; Herrick-Davis, K; Teitler, M	1
Bentley, J; Boess, FG; Bös, M; Bourson, A; Riemer, C; Sleight, AJ	1
Conklin, DS; Fitzgerald, LW; Hartig, PR; Iyer, G; Kostich, WA; Krause, CM; Largent, BL; Marshall, AP; Patterson, JP; Tran, DP	1
Benhamú, B; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Porras, E; Ramos, JA	1
Topliss, JG; Yoshida, F	1
Itoh, H; Muramatsu, I; Taniguchi, T; Yoshio, R	1
Andersen, K; Balle, T; Larsen, AK; Liljefors, T; Perregaard, J; Ramirez, MT; Søby, KK	1
Glennon, RA	1
Benhamú, B; Campillo, M; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Olivella, M; Pardo, L; Porras, E; Ramos, JA; Soto, LJ	1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D	1
Alonso, JM; Andrés, JI; Cid, JM; Díaz, A; Fernández, J; Gil, P; Iturrino, L; Megens, A; Sipido, VK; Trabanco, AA	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Andres-Mach, M; Czuczwar, S; Dawidowski, M; Herold, F; Kleps, J; Mazurek, A; Mazurek, AP; Nowak, G; Pluciński, F; Stachowicz, K; Stefanowicz, J; Szewczyk, B; Sławińska, A; Słowiński, T; Wolska, I; Łuszczki, JJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Frølund, B; Gloriam, DE; Isberg, V; Jensen, AA; Krall, J; Krogsgaard-Larsen, P; Pedersen, MH; Plath, N; Stensbøl, TB; Wellendorph, P	1
Andres-Mach, M; Bączek, T; Belka, M; Czuczwar, SJ; Gomółka, AE; Herold, F; Jastrzębska-Więsek, M; Nowak, G; Partyka, A; Siwek, A; Stefanowicz, J; Słowiński, T; Turło, J; Ulenberg, S; Wesołowska, A; Wróbel, MZ; Zagaja, M; Żołnierek, M; Łuszczki, JJ	1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J; Ulenberg, S	1
Ali, W; Głuch-Lutwin, M; Handzlik, J; Jastrzębska-Więsek, M; Kieć-Kononowicz, K; Kucwaj-Brysz, K; Kurczab, R; Latacz, G; Lubelska, A; Mordyl, B; Nasim, MJ; Partyka, A; Satała, G; Siwek, A; Sudoł, S; Wesołowska, A; Więcek, M; Łażewska, D	1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Podsadni, P; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J	1
Cools, AR	1
Dourish, CT	1
Buckland, PR; McGuffin, P; Oretti, RG; Spurlock, G	1
Deutch, AY; Fitzgerald, LW; Gasic, G; Heinemann, SF; Nestler, EJ	1
Alsayegh, L; Backstrom, JR; Berry, SA; Friedman, L; Roth, BL; Sanders-Bush, E; Willins, DL	1
Davidson, C; Ellinwood, EH; Lazarus, C; Lee, TH; Xiong, X	1
Iverson, S; Uetrecht, JP; Zahid, N	1
Canale, A; Crucitti, D; D'Arrigo, C; Malara, G; Muscatello, MR; Spina, E; Torre, DL; Zoccali, R	1
Di Chiara, G; Frau, R; Valentini, V	1
Cedro, C; Di Rosa, AE; La Torre, D; Meduri, M; Muscatello, MR; Neri, P; Spina, E; Zoccali, R	1
Heiser, P; Krieg, JC; Singh, S; Vedder, H	1
Appel, H; Fiedler, U; Jockers-Scherübl, MC; Klein, JP; Quante, A	1
Bajbouj, M; Danker-Hopfe, H; Gallinat, J; Hellen, F; Lang, UE; Lisanby, SH; Neu, P; Vesper, J	1
Biondi, M; Delle Chiaie, R; Fiorentini, S; Salviati, M	1
Chaput, C; Mannoury La Cour, C; Millan, MJ; Touzard, M	1
Lin, D; Lin, GY; Pan, XJ; Wang, XB; Wang, XQ; Wu, JZ; Xiang, Z	1

Reviews

1 review(s) available for mianserin and clozapine

Article	Year
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14 Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists	2003

Trials

3 trial(s) available for mianserin and clozapine

Article	Year
The effect of mirtazapine augmentation of clozapine in the treatment of negative symptoms of schizophrenia: a double-blind, placebo-controlled study. International clinical psychopharmacology, 2004, Volume: 19, Issue:2 Topics: Adrenergic alpha-Antagonists; Adult; Antipsychotic Agents; Clozapine; Double-Blind Method; Drug Synergism; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Psychiatric Status Rating Scales; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT3; Schizophrenia; Serotonin Antagonists; Time Factors; Treatment Outcome	2004
Motor cortex excitability after vagus nerve stimulation in major depression. Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2 Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid	2007
Add-on mirtazapine enhances effects on cognition in schizophrenic patients under stabilized treatment with clozapine. Experimental and clinical psychopharmacology, 2007, Volume: 15, Issue:6 Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Chronic Disease; Clozapine; Cognition; Cognition Disorders; Diagnostic and Statistical Manual of Mental Disorders; Drug Synergism; Female; Humans; Male; Mianserin; Mirtazapine; Schizophrenia; Time Factors	2007

Other Studies

46 other study(ies) available for mianserin and clozapine

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists. Journal of medicinal chemistry, 1984, Volume: 27, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction	1984
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Molecular pharmacology, 1993, Volume: 43, Issue:3 Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection	1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24 Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection	1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Molecular pharmacology, 1993, Volume: 44, Issue:2 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists	1993
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation. Proceedings of the National Academy of Sciences of the United States of America, 1993, Sep-15, Volume: 90, Issue:18 Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; CHO Cells; Cricetinae; Cyclic AMP; DNA; Genomic Library; Kinetics; Lysergic Acid Diethylamide; Mianserin; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Rats; Receptors, Serotonin; Restriction Mapping; Serotonin; Serotonin Receptor Agonists; Transfection	1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. Journal of neurochemistry, 1996, Volume: 66, Issue:1 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity	1996
Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor. Molecular pharmacology, 1997, Volume: 52, Issue:3 Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cloning, Molecular; Cricetinae; Dogs; Drug Interactions; Ergolines; Guinea Pigs; Humans; Kidney; Ligands; Lysergic Acid Diethylamide; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin; Threonine; Tryptamines	1997
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1 Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine	1998
Creation of a constitutively activated state of the 5-hydroxytryptamine2A receptor by site-directed mutagenesis: inverse agonist activity of antipsychotic drugs. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1 Topics: Animals; Antipsychotic Agents; COS Cells; Mutagenesis, Site-Directed; Phosphatidylinositols; Protein Conformation; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship	1998
The 5-hydroxytryptamine6 receptor-selective radioligand [3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum. Molecular pharmacology, 1998, Volume: 54, Issue:3 Topics: Aminopyridines; Animals; Binding Sites; Corpus Striatum; HeLa Cells; Humans; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Swine; Tritium	1998
High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action. Journal of neurochemistry, 1999, Volume: 72, Issue:5 Topics: Amphetamines; Binding, Competitive; Cell Line; Ergolines; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hydrolysis; Isomerism; Ligands; Models, Biological; Phosphatidylinositols; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone	1999
First pharmacophoric hypothesis for 5-HT7 antagonism. Bioorganic & medicinal chemistry letters, 2000, May-15, Volume: 10, Issue:10 Topics: Animals; Cell Membrane; Drug Design; Drug Evaluation, Preclinical; Hypothalamus; Models, Molecular; Rats; Receptors, Serotonin; Reproducibility of Results; Serotonin Antagonists; Structure-Activity Relationship	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes. Japanese journal of pharmacology, 2001, Volume: 86, Issue:2 Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dogs; Humans; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists	2001
Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists. Journal of medicinal chemistry, 2003, Jan-16, Volume: 46, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Azoles; Brain; Cell Line; Cricetinae; Humans; Imidazoles; In Vitro Techniques; Indoles; Pyridines; Pyrimidines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship; Triazoles	2003
Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives. Journal of medicinal chemistry, 2003, Dec-18, Volume: 46, Issue:26 Topics: Animals; Binding, Competitive; Computer Simulation; Drug Design; Hypothalamus; In Vitro Techniques; Lactams; Ligands; Male; Models, Molecular; Molecular Conformation; Naphthalenes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides; Thiazoles	2003
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2 Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists	2004
Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents. Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Furans; Heterocyclic Compounds, 4 or More Rings; Humans; In Vitro Techniques; Mice; Psychotropic Drugs; Radioligand Assay; Rats; Stereoisomerism; Structure-Activity Relationship	2005
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Synthesis and biological investigation of potential atypical antipsychotics with a tropane core. Part 1. European journal of medicinal chemistry, 2011, Volume: 46, Issue:9 Topics: Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Mice; Models, Molecular; Radioligand Assay; Rats; Receptors, Neurotransmitter; Structure-Activity Relationship; Tropanes	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Azepines; Biological Availability; Cognition; Drug Design; HEK293 Cells; Humans; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists	2013
Synthesis and biological investigation of new equatorial (β) stereoisomers of 3-aminotropane arylamides with atypical antipsychotic profile. Bioorganic & medicinal chemistry, 2016, 09-15, Volume: 24, Issue:18 Topics: Animals; Antipsychotic Agents; Benzene Derivatives; Dopamine D2 Receptor Antagonists; Male; Mice; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin 5-HT2 Receptor Antagonists; Stereoisomerism; Structure-Activity Relationship; Tropanes	2016
Synthesis of novel pyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT European journal of medicinal chemistry, 2019, Mar-15, Volume: 166 Topics: Animals; Chemistry Techniques, Synthetic; Drug Design; Ligands; Mice; Pyrimidines; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Tryptamines	2019
Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT European journal of medicinal chemistry, 2019, Sep-15, Volume: 178 Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Image Processing, Computer-Assisted; Ligands; Locomotion; Models, Molecular; Molecular Structure; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship	2019
Synthesis of new 5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT European journal of medicinal chemistry, 2019, Oct-15, Volume: 180 Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Ligands; Male; Mice; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Receptor, Serotonin, 5-HT1A; RNA-Binding Proteins; Structure-Activity Relationship; Tryptamines	2019
The nucleus accumbens and antidepressants: modulation of ergometrine-induced hyperactivity by typical and atypical antidepressants and neuroleptics in rats. Psychopharmacology, 1987, Volume: 92, Issue:3 Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Clorgyline; Clozapine; Desipramine; Ergonovine; Male; Mianserin; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Sulpiride; Zimeldine	1987
Behavioural effects of acute and chronic beta-phenylethylamine administration in the rat: evidence for the involvement of 5-hydroxytryptamine. Neuropharmacology, 1981, Volume: 20, Issue:11 Topics: Animals; Behavior, Animal; Clozapine; Crowding; Haloperidol; Male; Methysergide; Mianserin; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin	1981
Lack of effect of antipsychotic and antidepressant drugs on glutamate receptor mRNA levels in rat brains. Neuroscience letters, 1994, Aug-15, Volume: 177, Issue:1-2 Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Base Sequence; Brain Chemistry; Citalopram; Clozapine; Gene Expression Regulation; Haloperidol; Male; Mianserin; Molecular Sequence Data; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Schizophrenia; Sulpiride	1994
Regulation of cortical and subcortical glutamate receptor subunit expression by antipsychotic drugs. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:3 Pt 2 Topics: Animals; Antipsychotic Agents; Benzazepines; Cerebral Cortex; Clozapine; Corpus Striatum; Dopamine; Dopamine Antagonists; Gene Expression Regulation; Haloperidol; Humans; Limbic System; Male; Mesencephalon; Mianserin; Models, Neurological; Oxidopamine; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Salicylamides; Schizophrenia; Serotonin; Substantia Nigra	1995
Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo. Neuroscience, 1999, Volume: 91, Issue:2 Topics: 3T3 Cells; Animals; Antipsychotic Agents; Benzodiazepines; Cell Line; Clozapine; Dendrites; Fluorobenzenes; Haloperidol; Mianserin; Mice; Olanzapine; Piperidines; Pirenzepine; Prefrontal Cortex; Pyramidal Cells; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Recombinant Proteins; Risperidone; Ritanserin; Serotonin Antagonists; Transfection	1999
5-HT2 receptor antagonists given in the acute withdrawal from daily cocaine injections can reverse established sensitization. European journal of pharmacology, 2002, Oct-25, Volume: 453, Issue:2-3 Topics: Animals; Behavior, Animal; Clozapine; Cocaine; Injections; Ketanserin; Male; Mianserin; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Substance Withdrawal Syndrome	2002
Predicting drug-induced agranulocytosis: characterizing neutrophil-generated metabolites of a model compound, DMP 406, and assessing the relevance of an in vitro apoptosis assay for identifying drugs that may cause agranulocytosis. Chemico-biological interactions, 2002, Nov-10, Volume: 142, Issue:1-2 Topics: Agranulocytosis; Antipsychotic Agents; Apoptosis; Benzodiazepines; Chromatography, High Pressure Liquid; Chromatography, Liquid; Clozapine; Cyanides; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Hypochlorous Acid; Mass Spectrometry; Mianserin; Neutrophils; Nuclear Medicine; Olanzapine; Pirenzepine	2002
Lack of a pharmacokinetic interaction between mirtazapine and the newer antipsychotics clozapine, risperidone and olanzapine in patients with chronic schizophrenia. Pharmacological research, 2003, Volume: 48, Issue:4 Topics: Administration, Oral; Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clinical Trials as Topic; Clozapine; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Italy; Male; Mianserin; Middle Aged; Mirtazapine; Olanzapine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Time Factors	2003
Noradrenaline transporter blockers raise extracellular dopamine in medial prefrontal but not parietal and occipital cortex: differences with mianserin and clozapine. Journal of neurochemistry, 2004, Volume: 88, Issue:4 Topics: Analysis of Variance; Animals; Cerebral Cortex; Clozapine; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Extracellular Space; Male; Mianserin; Microdialysis; Morpholines; Neural Pathways; Norepinephrine Plasma Membrane Transport Proteins; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Reboxetine; Serotonin Antagonists; Symporters; Time Factors	2004
Effects of different antipsychotics and the antidepressant mirtazapine on glucose transporter mRNA levels in human blood cells. Journal of psychiatric research, 2006, Volume: 40, Issue:4 Topics: Actins; Analysis of Variance; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Blood Cells; Clozapine; Glucose Transporter Type 3; Glucose Transporter Type 4; Glucose Transporter Type 5; Haloperidol; Humans; Mianserin; Mirtazapine; Olanzapine; RNA, Messenger; U937 Cells	2006
Massive creatine kinase elevations with quetiapine: report of two cases. Pharmacopsychiatry, 2006, Volume: 39, Issue:1 Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Creatine Kinase; Depressive Disorder, Major; Dibenzothiazepines; Humans; Male; Mianserin; Mirtazapine; Olanzapine; Pain; Psychotic Disorders; Quetiapine Fumarate	2006
An immunocapture/scintillation proximity analysis of G alpha q/11 activation by native serotonin (5-HT)2A receptors in rat cortex: blockade by clozapine and mirtazapine. Synapse (New York, N.Y.), 2009, Volume: 63, Issue:2 Topics: Adrenergic alpha-Antagonists; Amphetamines; Animals; Cerebral Cortex; Clozapine; GTP-Binding Protein alpha Subunits, Gq-G11; Male; Mianserin; Mirtazapine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Scintillation Counting; Serotonin Antagonists; Serotonin Receptor Agonists	2009
[Simultaneous determination of clozapine, olanzapine and mirtazapine in human plasma by LC-MS/MS]. Fa yi xue za zhi, 2009, Volume: 25, Issue:2 Topics: Benzodiazepines; Chromatography, Liquid; Clozapine; Forensic Toxicology; Humans; Mianserin; Mirtazapine; Olanzapine; Tandem Mass Spectrometry	2009