mianserin and buspirone

mianserin has been researched along with buspirone in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.00)18.7374
1990's5 (20.00)18.2507
2000's9 (36.00)29.6817
2010's9 (36.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Glennon, RA1
Amlaiky, N; Hen, R; Plassat, JL1
Arrang, JM; Diaz, J; Leurs, R; Ruat, M; Schwartz, JC; Tardivel-Lacombe, J; Traiffort, E1
Dokhan, R; el Ahmad, Y; Laurent, E; Maillet, P; Ollivier, R; Talab, A; Teste, JF; Tran, G1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Ali, W; Głuch-Lutwin, M; Handzlik, J; Jastrzębska-Więsek, M; Kieć-Kononowicz, K; Kucwaj-Brysz, K; Kurczab, R; Latacz, G; Lubelska, A; Mordyl, B; Nasim, MJ; Partyka, A; Satała, G; Siwek, A; Sudoł, S; Wesołowska, A; Więcek, M; Łażewska, D1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Podsadni, P; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J1
Ishibashi, Y; Ishima, T; Nakagawa, Y; Takashima, T; Yoshii, T1
Poyurovsky, M; Weizman, A2
Fava, M1
Andreev, BV; Kudriashova, MF1
Barreau, S; Belzung, C; Calatayud, F; Le Guisquet, AM1
Benyamina, A; Blecha, L; Lecacheux, M; Lukasiewcz, M; Reynaud, M1
Grubb, MF; Humphreys, WG; Josephs, JL1
Bielefeldt, K; Szigethy, E; Thorkelson, G1

Reviews

4 review(s) available for mianserin and buspirone

ArticleYear
Central serotonin receptors as targets for drug research.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin

1987
New approaches to the treatment of refractory depression.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 1

    Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Drug Therapy, Combination; Humans; Lithium; Mianserin; Mirtazapine; Monoamine Oxidase Inhibitors; Morpholines; Pindolol; Piperazines; Reboxetine; Selective Serotonin Reuptake Inhibitors; Thyroxine; Triazoles; Triiodothyronine

2000
Pharmacotherapy and psychotherapy in cannabis withdrawal and dependence.
    Expert review of neurotherapeutics, 2008, Volume: 8, Issue:3

    Topics: Behavior Therapy; Buspirone; Cannabinoids; Cognitive Behavioral Therapy; Combined Modality Therapy; Dronabinol; Humans; Marijuana Abuse; Mianserin; Mirtazapine; Motivation; Piperidines; Psychotherapy; Psychotropic Drugs; Pyrazoles; Randomized Controlled Trials as Topic; Rimonabant; Substance Withdrawal Syndrome

2008
Empirically Supported Use of Psychiatric Medications in Adolescents and Adults with IBD.
    Inflammatory bowel diseases, 2016, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Affect; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Bupropion; Buspirone; Depression; Gastrointestinal Tract; Humans; Immunity; Inflammatory Bowel Diseases; Mianserin; Mirtazapine; Pain; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Young Adult

2016

Trials

1 trial(s) available for mianserin and buspirone

ArticleYear
Serotonergic agents in the treatment of acute neuroleptic-induced akathisia: open-label study of buspirone and mianserin.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:5

    Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Buspirone; Female; Humans; Male; Mianserin; Middle Aged; Schizophrenia; Serotonin Agents

1997

Other Studies

20 other study(ies) available for mianserin and buspirone

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Sep-15, Volume: 90, Issue:18

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; CHO Cells; Cricetinae; Cyclic AMP; DNA; Genomic Library; Kinetics; Lysergic Acid Diethylamide; Mianserin; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Rats; Receptors, Serotonin; Restriction Mapping; Serotonin; Serotonin Receptor Agonists; Transfection

1993
New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands.
    Journal of medicinal chemistry, 1997, Mar-14, Volume: 40, Issue:6

    Topics: Adenylyl Cyclases; Animals; Behavior, Animal; Binding, Competitive; Colforsin; Cyclic AMP; Electrophysiology; Enzyme Activation; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Piperazines; Protein Binding; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship

1997
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physical binding pocket induction for affinity prediction.
    Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19

    Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT
    European journal of medicinal chemistry, 2019, Sep-15, Volume: 178

    Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Image Processing, Computer-Assisted; Ligands; Locomotion; Models, Molecular; Molecular Structure; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship

2019
Synthesis of new 5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Ligands; Male; Mice; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Receptor, Serotonin, 5-HT1A; RNA-Binding Proteins; Structure-Activity Relationship; Tryptamines

2019
Involvement of GABA(B) receptor systems in action of antidepressants: baclofen but not bicuculline attenuates the effects of antidepressants on the forced swim test in rats.
    Brain research, 1996, Feb-19, Volume: 709, Issue:2

    Topics: Animals; Antidepressive Agents; Baclofen; Bicuculline; Buspirone; Desipramine; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Male; Mianserin; Motor Activity; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Swimming; Volition

1996
[Neuropharmacological analysis of participation of the serotoninergic system in hyperalgesia in neurotized rats].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2000, Volume: 86, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Buspirone; Fluoxetine; Hyperalgesia; Male; Mianserin; Neurotic Disorders; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists

2000
Serotonin-based pharmacotherapy for acute neuroleptic-induced akathisia: a new approach to an old problem.
    The British journal of psychiatry : the journal of mental science, 2001, Volume: 179

    Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Buspirone; Clinical Trials as Topic; Cyproheptadine; Humans; Mianserin; Ritanserin; Serotonin Agents

2001
An investigation of the mechanisms responsible for acute fluoxetine-induced anxiogenic-like effects in mice.
    Behavioural pharmacology, 2001, Volume: 12, Issue:3

    Topics: Animals; Anxiety; Arousal; Buspirone; Diazepam; Exploratory Behavior; Fluoxetine; Humans; Male; Mianserin; Mice; Mice, Inbred BALB C; Motor Activity; Quinolines; Receptors, Dopamine; Receptors, Neurotransmitter; Social Environment

2001
A semi-automated method for the integrated evaluation of half-life and metabolic soft spots of discovery compounds.
    Bioanalysis, 2012, Volume: 4, Issue:14

    Topics: Animals; Automation; Biotransformation; Buspirone; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Dogs; Drug Evaluation, Preclinical; Half-Life; Humans; Mianserin; Microsomes, Liver; Mirtazapine; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Verapamil

2012