Page last updated: 2024-08-23

mezlocillin and tobramycin

mezlocillin has been researched along with tobramycin in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199016 (69.57)18.7374
1990's2 (8.70)18.2507
2000's4 (17.39)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Bale, M; Barrett, M; Cabezudo, I; Pfaller, MA; Wenzel, RP1
Ramirez-Ronda, CH; Rivera-Vazquez, CR; Rodriguez, JR; Saavedra, S1
Chastagner, P; Flamant, F; Hartmann, O; Kalifa, C; Lemerle, J; Patte, C; Tancrede, C1
Cohen, MS; Faubion, C; Gordon, LI; McMahan, R; Murphy, RL; Pegram, PS; Phair, JP; Saviteer, S; Washton, H1
Cesari, C; Cimino, M; Fenner, J; Rotstein, C; Winkey, K1
Watanakunakorn, C1
Mellinghoff, D; Shah, PM; Stille, W1
Carpenter, T; Chambers, HF; Hackbarth, CJ; Kapusnik, JE; Sande, MA1
Brooks, GF; Mordenti, J; Ries, C; Tseng, A; Unadkat, N1
Heimann, G1
Amgwerd, R; Rauh, G; Sonnabend, W1
Hellriegel, KP; Kindler, J; Kress, M; Wittenberg, C1
Aznar, J; Iglesias, MC; Martin, E; Nogales, MC; Perea, EJ1
Bodey, GP; Issell, BF1
Pickering, LK; Rutherford, I1
Henderson, JL; Kline, BJ; Polk, RE1
Eder, W; Förstl, H; Lang, M; Ruckdeschel, G1
Danko, LS; Greenberg, RN; Meade, DW1

Trials

4 trial(s) available for mezlocillin and tobramycin

ArticleYear
A comparative analysis of aztreonam + clindamycin versus tobramycin + clindamycin or amikacin + mezlocillin in the treatment of gram-negative lower respiratory tract infections.
    Chemotherapy, 1989, Volume: 35 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Amikacin; Aztreonam; Bacterial Infections; Clindamycin; Clinical Trials as Topic; Cross Infection; Drug Therapy, Combination; Gram-Negative Bacteria; Humans; Male; Mezlocillin; Middle Aged; Pneumonia; Random Allocation; Tobramycin

1989
Prospective comparative trial of short course (four day) and continuous tobramycin in combination with cefoperazone or mezlocillin in febrile, granulocytopenic patients.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Agranulocytosis; Bacterial Infections; Cefoperazone; Drug Therapy, Combination; Female; Fever; Humans; Leukocyte Count; Male; Mezlocillin; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Tobramycin

1989
Cefoperazone plus piperacillin versus mezlocillin plus tobramycin as empiric therapy for febrile episodes in neutropenic patients.
    The American journal of medicine, 1988, Jul-25, Volume: 85, Issue:1A

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Cefoperazone; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fever; Humans; Male; Mezlocillin; Middle Aged; Neutropenia; Piperacillin; Prospective Studies; Random Allocation; Tobramycin

1988
Empiric antibiotic treatment of infections in myelosuppressed cancer patients. Preliminary results.
    Infection, 1982, Volume: 10 Suppl 3

    Topics: Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Cefamandole; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Leukemia; Lymphoma; Mezlocillin; Middle Aged; Neoplasms; Penicillins; Prospective Studies; Random Allocation; Sisomicin; Tobramycin

1982

Other Studies

19 other study(ies) available for mezlocillin and tobramycin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
In vitro comparison of mezlocillin and piperacillin plus tobramycin or gentamicin versus 100 gram-negative nosocomial bloodstream isolates.
    American journal of infection control, 1990, Volume: 18, Issue:4

    Topics: Drug Synergism; Drug Therapy, Combination; Gentamicins; Gram-Negative Bacteria; Hospitals, University; Humans; Mezlocillin; Microbial Sensitivity Tests; Piperacillin; Tobramycin

1990
Role of parenteral antibiotherapy in gastrointestinal tract flora suppression. A study in children treated with high-dose chemotherapy and autologous bone marrow transplantation.
    Bone marrow transplantation, 1989, Volume: 4, Issue:4

    Topics: Adolescent; Agranulocytosis; Bone Marrow Transplantation; Cefotaxime; Child; Child, Preschool; Digestive System; Dose-Response Relationship, Drug; Drug Combinations; Feces; Female; Gentamicins; Gram-Positive Bacteria; Humans; Infusions, Parenteral; Male; Mezlocillin; Moxalactam; Sulfamethizole; Suppression, Genetic; Tobramycin; Transplantation, Autologous; Trimethoprim

1989
Effects of inoculum size on the activity of carboxy- and ureido-penicillins and effects of combinations of ureido-penicillins with aminoglycosides against resistant Pseudomonas aeruginosa.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 17, Issue:1

    Topics: Azlocillin; Carbenicillin; Dose-Response Relationship, Drug; Drug Combinations; Gentamicins; Mezlocillin; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Piperacillin; Pseudomonas aeruginosa; Ticarcillin; Tobramycin

1986
[Ciprofloxacin in combination with other antimicrobial substances].
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:3

    Topics: Anti-Bacterial Agents; Azlocillin; Bacteria; Ciprofloxacin; Drug Interactions; Imipenem; Mezlocillin; Microbial Sensitivity Tests; Thienamycins; Tobramycin

1988
Single, large, daily dosing versus intermittent dosing of tobramycin for treating experimental pseudomonas pneumonia.
    The Journal of infectious diseases, 1988, Volume: 158, Issue:1

    Topics: Animals; Drug Therapy, Combination; Guinea Pigs; Mezlocillin; Neutropenia; Pneumonia; Pseudomonas Infections; Tobramycin

1988
Vancomycin-induced neutropenia complicating bone marrow recovery in a patient with leukemia. Case report and review of the literature.
    The American journal of medicine, 1986, Volume: 80, Issue:2

    Topics: Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Humans; Infusions, Parenteral; Leukemia, Myeloid; Male; Mezlocillin; Neutropenia; Tobramycin; Vancomycin

1986
Renal toxicity of aminoglycosides in the neonatal period.
    Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4

    Topics: Acetylglucosaminidase; Aminoglycosides; Aminopeptidases; Ampicillin; Anti-Bacterial Agents; CD13 Antigens; Child, Preschool; gamma-Glutamyltransferase; Gentamicins; Glucuronidase; Humans; Infant; Infant, Newborn; Kidney; Kidney Tubules; Kinetics; Mezlocillin; Sepsis; Tobramycin

1983
[Mezlocillin in the antibiotic therapy of severe bacterial infections in visceral surgery].
    Infection, 1982, Volume: 10 Suppl 3

    Topics: Abdomen; Adult; Aged; Bacterial Infections; Empyema; Fatty Acids; Female; Humans; Intestinal Diseases; Male; Mezlocillin; Middle Aged; Penicillins; Postoperative Complications; Surgical Wound Infection; Thoracic Surgery; Tobramycin

1982
Synergy between cefotaxime, cefsulodin, azlocillin, mezlocillin and aminoglycosides against carbenicillin resistant or sensitive Pseudomonas aeruginosa.
    The Journal of antimicrobial chemotherapy, 1980, Volume: 6, Issue:4

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Azlocillin; Carbenicillin; Cefotaxime; Cefsulodin; Cephalosporins; Dibekacin; Drug Synergism; Gentamicins; Mezlocillin; Penicillin Resistance; Penicillins; Pseudomonas aeruginosa; Sisomicin; Tobramycin

1980
Mezlocillin for treatment of infections in cancer patients.
    Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Aged; Bacteria; Bacterial Infections; Drug Synergism; Humans; Immunosuppression Therapy; Mezlocillin; Microbial Sensitivity Tests; Middle Aged; Neoplasms; Neutropenia; Penicillins; Tobramycin

1980
Effect of concentration and time upon inactivation of tobramycin, gentamicin, netilmicin and amikacin by azlocillin, carbenicillin, mecillinam, mezlocillin and piperacillin.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:2

    Topics: Amdinocillin; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Azlocillin; Carbenicillin; Gentamicins; Mezlocillin; Netilmicin; Penicillins; Piperacillin; Time Factors; Tobramycin

1981
In vitro inactivation of gentamicin, tobramycin, and netilmicin by carbenicillin, azlocillin, or mezlocillin.
    American journal of hospital pharmacy, 1981, Volume: 38, Issue:8

    Topics: Anti-Bacterial Agents; Azlocillin; Carbenicillin; Chemistry, Pharmaceutical; Drug Incompatibility; Gentamicins; Mezlocillin; Netilmicin; Penicillins; Temperature; Tobramycin

1981
Septicemia caused by Kingella kingae.
    European journal of clinical microbiology, 1984, Volume: 3, Issue:3

    Topics: Acute Disease; Female; Gastroenteritis; Humans; Mezlocillin; Middle Aged; Neisseriaceae; Sepsis; Tobramycin

1984
Comparison of the synergic activity of aztreonam or tobramycin plus piperacillin or mezlocillin.
    The Journal of antimicrobial chemotherapy, 1993, Volume: 32, Issue:2

    Topics: Aztreonam; Drug Synergism; Drug Therapy, Combination; Humans; Mezlocillin; Microbial Sensitivity Tests; Piperacillin; Tobramycin

1993