Page last updated: 2024-08-23

mezlocillin and oxacillin

mezlocillin has been researched along with oxacillin in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199030 (76.92)18.7374
1990's5 (12.82)18.2507
2000's2 (5.13)29.6817
2010's2 (5.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Lim, SP; Nikaido, H1
Anderson, KC; Kellogg, GE; Sarkar, A1
Chyský, V; Hullmann, R2
Adam, D; Bauer, W1
Kurz, R1
Schöch, G1
Elies, W; Hermes, H1
Karhoff, HL; König, HJ; Mewe, R1
Maier, H; Schlegel, P; Zerfowski, M1
Burroughs, SF; Johnson, GJ1
Hallfeldt, K; Mandelkow, H; Rolle, A; Schweiberer, L; Thetter, O1
Engel, K; Wildfeuer, A1
Gerlach, K; Pape, H1
Dumbach, J; Spitzer, W1
Elies, W1
Bonini, W; Broffoni, T; De Lalla, F1
Gerlach, KL; Reuter, HD; Thiele, S; Walz, C1
Bardua, R; Blenk, H; Koch, A; Lenz, J; Marohl, K2
Bardua, R; Koch, A; Lenz, J; Marohl, K1
Meier, J1
Huk, I; Rotter, M; Schemper, M; Schiessel, R; Starlinger, M; Wewalka, G; Wunderlich, M1
Stütz, G1
Adam, D; Brandstätter, G; Chyský, V; Kratochvil, P1
Endler, M; Kraft, A; Wewalka, G1
Adam, D; Bordt, J; Holzgreve, W; Wagner, H1
Hadid, D1
Berghoff, D; Reynders-Frederix, V; Schassan, HH; Wittmann, DH1
Amir-Moazami, B; Engel, K; Hahn, T; Karschnia, R1
Grundmann, R; Kraume, R1
Belli, L; Freylejer, A; Gandolfo, S; Ginesín, LM; Ríos, JF1
Menz, G1
Adam, D; Chyský, V; Wilhelm, K1
Kampf, D1
Fischer-Brügge, U; Reinel, D1
Jansen, W1

Trials

12 trial(s) available for mezlocillin and oxacillin

ArticleYear
[Therapy with an antibiotic combination mezlocillin/oxacillin and clinical experience/First communication: Adults (author's transl)].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:12a

    Topics: Adult; Bacterial Infections; Clinical Trials as Topic; Drug Combinations; Female; Humans; Male; Mezlocillin; Middle Aged; Oxacillin; Penicillins

1979
[Pharmacokinetic studies with a combination of mezlocillin-oxacillin].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:12a

    Topics: Adult; Drug Combinations; Female; Humans; Kinetics; Male; Mezlocillin; Middle Aged; Oxacillin; Penicillins; Time Factors

1979
[Perioperative preventive use of antibiotics in neurosurgery. Experience with a fixed antibiotic combination of mezlocillin and oxacillin (optocillin)].
    Neurochirurgia, 1991, Volume: 34, Issue:1

    Topics: Central Nervous System Diseases; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Mezlocillin; Microbial Sensitivity Tests; Oxacillin; Premedication; Risk Factors; Surgical Wound Infection

1991
[Perioperative preventive use of antibiotics in thoracic surgery--results of a controlled randomized study with optocillin].
    Pneumologie (Stuttgart, Germany), 1990, Volume: 44 Suppl 1

    Topics: Drug Administration Schedule; Drug Therapy, Combination; Humans; Lung Diseases; Mezlocillin; Oxacillin; Premedication; Randomized Controlled Trials as Topic; Risk Factors; Surgical Wound Infection

1990
Perioperative systemic antibiotics for prophylaxis of infections in breast surgery: sulbactam/ampicillin versus mezlocillin/oxacillin.
    Supplement to International journal of gynecology and obstetrics, 1989, Volume: 2

    Topics: Adult; Ampicillin; Breast; Drug Therapy, Combination; Female; Humans; Mezlocillin; Middle Aged; Oxacillin; Premedication; Prospective Studies; Randomized Controlled Trials as Topic; Sulbactam; Surgical Wound Infection

1989
Perioperative antibiotic prophylaxis in mandibular fracture treatment.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Clinical Trials as Topic; Humans; Mandibular Fractures; Mezlocillin; Oxacillin; Prospective Studies; Random Allocation; Surgical Wound Infection

1987
Short-term antibiotic prophylaxis in elective oral and maxillofacial surgery with mezlocillin and oxacillin.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Adolescent; Adult; Aged; Bacteria; Child; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Male; Maxillofacial Prosthesis; Mezlocillin; Middle Aged; Mouth Diseases; Oxacillin; Sepsis; Surgical Wound Infection

1987
Results of antibiotic prophylaxis in head and neck surgery.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Bacterial Infections; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Humans; Male; Mezlocillin; Middle Aged; Oxacillin; Prospective Studies; Random Allocation; Surgical Wound Infection

1987
Systemic chemoprophylaxis in pacemaker surgery: a prospective randomized study.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Aged; Clinical Trials as Topic; Drug Administration Schedule; Humans; Mezlocillin; Oxacillin; Pacemaker, Artificial; Prospective Studies; Random Allocation; Surgical Wound Infection

1987
Postoperative infections in colonic surgery after enteral bacitracin-neomycin-clindamycin or parenteral mezlocillin-oxacillin prophylaxis.
    The Journal of hospital infection, 1984, Volume: 5, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Bacitracin; Clindamycin; Clinical Trials as Topic; Colonic Diseases; Drug Therapy, Combination; Humans; Infusions, Parenteral; Mezlocillin; Middle Aged; Neomycin; Oxacillin; Premedication; Surgical Wound Infection; Therapeutic Irrigation

1984
[Advantages and hazards of preventing infection following cesarean section--clinical and bacteriologic results of a high-dosage treatment with mezlocillin and oxacillin short-term preventive following clamping of the umbilical cord].
    Geburtshilfe und Frauenheilkunde, 1984, Volume: 44, Issue:3

    Topics: Cesarean Section; Clinical Trials as Topic; Constriction; Female; Humans; Mezlocillin; Oxacillin; Pregnancy; Premedication; Prospective Studies; Surgical Wound Infection; Time Factors; Umbilical Cord

1984
Fixed combination mezlocillin/oxacillin injected intramuscularly. Comparative study of local tolerability compared with ampicillin and determination of effectiveness and tolerability in the treatment of surgical and urinary tract infections.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:10

    Topics: Adolescent; Adult; Ampicillin; Drug Combinations; Female; Humans; Injections, Intramuscular; Male; Mezlocillin; Middle Aged; Oxacillin; Penicillins; Surgical Wound Infection; Urinary Tract Infections

1980

Other Studies

27 other study(ies) available for mezlocillin and oxacillin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Bacterial Outer Membrane Proteins; beta-Lactamases; Cephalosporins; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Kinetics; Lipoproteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Penicillins; Plasmids

2010
Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics.
    European journal of medicinal chemistry, 2012, Volume: 52

    Topics: Anti-Bacterial Agents; beta-Lactams; Computational Biology; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; Ligands; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Regression Analysis; Thermodynamics

2012
[Experience with the combination mezlocillin/oxacillin in severe bacterial infections in a children's surgical ward (author's transl)].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:12a

    Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Cross Infection; Drug Combinations; Female; Humans; Infant; Male; Mezlocillin; Oxacillin; Penicillins

1979
[Clinical studies with a mezlocillin-oxacillin combination in a children's intensive care ward].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:12a

    Topics: Bacterial Infections; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units; Male; Mezlocillin; Oxacillin; Penicillins

1979
[Therapy with an antibiotic combination mezlocillin/oxacillin and clinical experience/Second communication: Children (author's transl)].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:12a

    Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Male; Mezlocillin; Oxacillin; Penicillins

1979
[Early complications following stapedectomy--surgical or conservative treatment?].
    HNO, 1990, Volume: 38, Issue:2

    Topics: Adult; Auditory Threshold; Bone Conduction; Cefotiam; Dexamethasone; Follow-Up Studies; Granuloma; Hearing Loss; Hearing Loss, Conductive; Hearing Loss, Sensorineural; Humans; Hydroxyethyl Starch Derivatives; Meniere Disease; Mezlocillin; Nystagmus, Pathologic; Oxacillin; Postoperative Complications; Prospective Studies; Stapes Surgery

1990
[Excretion of beta-lactam antibiotics in human parotid saliva].
    HNO, 1991, Volume: 39, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Cefotaxime; Cefotiam; Half-Life; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Mezlocillin; Microbial Sensitivity Tests; Oxacillin; Parotid Gland; Saliva

1991
Beta-lactam antibiotic-induced platelet dysfunction: evidence for irreversible inhibition of platelet activation in vitro and in vivo after prolonged exposure to penicillin.
    Blood, 1990, Apr-01, Volume: 75, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Carbon Radioisotopes; Collagen; Epinephrine; Humans; In Vitro Techniques; Kinetics; Mezlocillin; Oxacillin; Penicillins; Platelet Activation; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Radioisotope Dilution Technique; Serotonin

1990
[Induced aggregation ex vivo in mandibular surgical interventions with preventive use of Optocillin].
    Medizinische Klinik (Munich, Germany : 1983), 1988, Feb-26, Volume: 83, Issue:4

    Topics: Adolescent; Adult; Bone Plates; Drug Combinations; Female; Fracture Fixation, Internal; Humans; Male; Mandibular Fractures; Mezlocillin; Middle Aged; Oxacillin; Platelet Aggregation; Premedication; Surgical Wound Infection

1988
The results of perioperative prophylaxis in thoracic surgery.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Bacteria; Drug Therapy, Combination; Humans; Mezlocillin; Microbial Sensitivity Tests; Oxacillin; Surgical Wound Infection; Thoracic Surgery

1987
Critical evaluation of common clinical parameters of postoperative pneumonia after thoracic surgery with perioperative prophylaxis.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Drug Therapy, Combination; Female; Humans; Male; Mezlocillin; Middle Aged; Oxacillin; Pneumonia; Postoperative Complications; Thoracic Surgery; Thoracotomy

1987
Perioperative prophylaxis and postoperative treatment of pneumonia with oxacillin and acylureidopenicillin in thoracic surgery.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Cross Infection; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Mezlocillin; Middle Aged; Oxacillin; Pneumonia; Postoperative Complications; Surgical Wound Infection; Thoracic Surgery

1987
[Experiences with a set antibiotic combination of mezlocillin and oxacillin (Optocillin) in jaw surgery].
    ZWR, 1985, Volume: 94, Issue:5

    Topics: Bacteria; Drug Combinations; Humans; Intraoperative Care; Mezlocillin; Orthognathic Surgical Procedures; Oxacillin

1985
[Use of a mezlocillin and oxacillin combination in surgery].
    Die Medizinische Welt, 1982, Jul-02, Volume: 33, Issue:26

    Topics: Adolescent; Adult; Aged; Bacterial Infections; Child; Cross Infection; Drug Therapy, Combination; Female; Humans; Male; Mezlocillin; Middle Aged; Oxacillin; Penicillins; Surgical Procedures, Operative

1982
[Mezlocillin and oxacillin concentrations in the bile of the choledochus].
    Infection, 1982, Volume: 10 Suppl 3

    Topics: Aged; Bile; Common Bile Duct; Female; Humans; Male; Mezlocillin; Middle Aged; Oxacillin; Penicillins

1982
[Antibiotic concentrations in wound secretions and bone during the simultaneous administration of mezlocillin and oxacillin].
    Infection, 1982, Volume: 10 Suppl 3

    Topics: Aged; Bone and Bones; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Mezlocillin; Middle Aged; Oxacillin; Penicillins; Surgical Wound Infection; Wounds and Injuries

1982
[Penetration of mezlocillin and oxacillin into the glandular and adipose tissue of the breast after simultaneous intravenous infusion. A pharmacokinetic study].
    Geburtshilfe und Frauenheilkunde, 1983, Volume: 43, Issue:1

    Topics: Adipose Tissue; Adolescent; Adult; Aged; Breast; Drug Combinations; Female; Humans; Infusions, Parenteral; Mastectomy; Mezlocillin; Middle Aged; Oxacillin; Penicillins; Postoperative Complications; Preoperative Care; Tissue Distribution

1983
[Mezlocillin or the combination preparation mezlocillin/oxacillin 2:1 in diseases in pediatric surgery. Clinical experiences].
    Die Medizinische Welt, 1983, Feb-25, Volume: 34, Issue:8

    Topics: Adolescent; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Combinations; Humans; Infant; Infant, Newborn; Mezlocillin; Microbial Sensitivity Tests; Oxacillin; Penicillins; Staphylococcal Infections; Surgical Wound Infection

1983
[Use of hydroxyapatite for determination of antibiotic concentrations in bone].
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Bone and Bones; Chromatography; Durapatite; Female; Humans; Hydroxyapatites; Kinetics; Male; Mezlocillin; Oxacillin; Penicillins

1983
[Perioperative antibiotic prophylaxis and the risk of wound infection in kidney transplantation].
    Fortschritte der Medizin, 1984, Dec-20, Volume: 102, Issue:47-48

    Topics: Adolescent; Adult; Bacteriological Techniques; Child; Drug Combinations; Female; Humans; Kidney Transplantation; Male; Mezlocillin; Middle Aged; Oxacillin; Premedication; Prospective Studies; Risk; Surgical Wound Infection; Urinary Tract Infections

1984
[The effect of a mezlocillin-oxacillin combination on ADP-induced thrombocyte aggregation in vitro].
    Die Medizinische Welt, 1981, Oct-16, Volume: 32, Issue:42

    Topics: Adenosine Diphosphate; Adult; Drug Combinations; Humans; Male; Mezlocillin; Oxacillin; Penicillins; Platelet Aggregation

1981
Antibiotic concentrations in blood and tissue. Intraoperative ischemia as a model for the determination of tissue concentrations using mezlocillin and oxacillin as examples.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:11

    Topics: Adult; Anti-Bacterial Agents; Female; Hemoglobins; Humans; Intraoperative Period; Ischemia; Male; Mezlocillin; Models, Biological; Oxacillin; Penicillins; Time Factors; Tissue Distribution

1981
Effects of mezlocillin on the pharmacokinetics of oxacillin and dicloxacillin.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 11 Suppl C

    Topics: Adult; Aged; Dicloxacillin; Drug Interactions; Humans; Kidney Diseases; Kinetics; Mezlocillin; Middle Aged; Models, Biological; Oxacillin

1983
[Effectiveness of a mezlocillin-oxacillin combination in the treatment of gonorrhea].
    Die Medizinische Welt, 1983, Oct-07, Volume: 34, Issue:40

    Topics: Adolescent; Adult; Drug Administration Schedule; Drug Combinations; Gonorrhea; Humans; Injections, Intravenous; Male; Mezlocillin; Oxacillin; Penicillins

1983
[Treatment of severe respiratory and urinary tract infections in older patients].
    Fortschritte der Medizin, 1980, Jan-10, Volume: 98, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Drug Combinations; Female; Humans; Male; Mezlocillin; Oxacillin; Penicillin Resistance; Penicillins; Respiratory Tract Infections; Urinary Tract Infections

1980