Page last updated: 2024-08-23

mezlocillin and metronidazole

mezlocillin has been researched along with metronidazole in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199026 (68.42)18.7374
1990's5 (13.16)18.2507
2000's6 (15.79)29.6817
2010's0 (0.00)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Abri, O; Gemperle, A; Hopfenmüller, W; Kraas, E; Langmark, H; Löhde, E; Scholz, L1
Heizmann, WR; Nagy, E; Werner, H1
Bittner, R; Butters, M; Kapfer, X; Rampf, W1
Brown, M; Conn, G; Davidson, PM; McClure, A; Murray, WR; Porteous, C; Rawluk, D; Scott, R1
Dickinson, IK; Griggs, NJ; Kelleher, JP; Moat, N; Rimmer, DM; Stubbs, RS1
Cann, KJ; Crawfurd, E; George, C; Payne-James, J; Rogers, TR; Watkins, RM1
Diamond, T; Hanna, WA; Mulholland, CK; Parks, TG1
Cole, DS; Rowe-Jones, DC1
Anagnostou, M; Bleier, R; Borneff, M; Geyer, G; Hartmetz, G; Roser, F1
Heymann, H; Jung, D; Mendel, V1
Burkardt, F; Grundmann, R; Koelschbach, D; Scholl, H1
Bawdon, RE; Cushing, RD; Ledgerwood, AM; Lucas, CE; Sugawa, C; Wallace, JR1
Esch, B; Wenzel, M1
Graf, D; Höllwarth, M; Kurz, R; Sauer, H1
Berker-von-Schlichting, C; Hancke, E; Jensen, JC; Marklein, G; Stute, H; Voigt, U1
Krasemann, C; Mendling, W1
Cheng, N; Chow, AW; Whiting, JL1
García Díaz, S; García Fernández, S; Jiménez García, A; Ortega Bevia, JM; Prada Lorenzo, D1
Lefrock, JL; Weber, SJ1
Ambrose, NS; Burdon, DW; Keighley, MR1
Daschner, FD1
Höffler, U; Niederau, W; Pape, W; Pulverer, G; Schaal, KP1
Schmidt, C; Walden, M; Wenzel, M1
Jacob, G; McIntosh, GS; Noone, P; Townell, NH1
Alexander-Williams, J; Ambrose, NS; Keighley, MR1
Chandrasekar, PH; Chokkavelu, V; Kannangara, DW; Le Frock, JL; Rolston, KV1
Guthy, E1
Bunke, HJ; Düsel, W; Meyer, G; Schultheis, A1
Debus, S; Kozuschek, W; Mittelkötter, U; Niedmann, M; Reith, HB1
Betriu, C; Gómez, M; Palau, ML; Picazo, JJ; Sánchez, A1
Beger, HG; Ebeling, P; Isenmann, R; Schwarz, M; Thomsen, J; Weikert, E1
Beger, HG; Gaus, W; Isenmann, R; Schwarz, M; Thomsen, J1
Hofmann, G; Kujath, P; Rauh, V; Weisser, C1
Haller, IE; Heisler, S; Helmke, C; Hunger, R; Kirbach, J; Kobelt, E; Lünse, S; Mantke, R; Meyer, J; Paasch, C; Schildberg, C1

Trials

17 trial(s) available for mezlocillin and metronidazole

ArticleYear
[Comparative analysis of mezlocillin/metronidazole and amoxicillin/clavulanic acid as "one shot" preventive antibiotic administration in colorectal interventions].
    Zentralblatt fur Chirurgie, 1992, Volume: 117, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Clavulanic Acids; Colectomy; Colorectal Neoplasms; Female; Humans; Infusions, Intravenous; Male; Metronidazole; Mezlocillin; Middle Aged; Surgical Wound Infection

1992
[Duration of the preventive use of antibiotics in colorectal surgery--single administration versus short-term prevention].
    Langenbecks Archiv fur Chirurgie, 1989, Volume: 374, Issue:5

    Topics: Aged; Colonic Neoplasms; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Mezlocillin; Microbial Sensitivity Tests; Middle Aged; Premedication; Prospective Studies; Randomized Controlled Trials as Topic; Rectal Neoplasms; Risk Factors; Surgical Wound Infection

1989
Peri-incisional mezlocillin versus rectal-metronidazole for wound infection prophylaxis.
    The Journal of hospital infection, 1985, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Appendectomy; Bacteroides fragilis; Bacteroides Infections; Child; Clinical Trials as Topic; Escherichia coli Infections; Female; Humans; Injections, Intramuscular; Male; Metronidazole; Mezlocillin; Middle Aged; Prospective Studies; Random Allocation; Rectum; Suppositories; Surgical Wound Infection

1985
Single dose mezlocillin versus three dose cefuroxime plus metronidazole for the prophylaxis of wound infection after large bowel surgery.
    The Journal of hospital infection, 1987, Volume: 9, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Colon; Drug Therapy, Combination; Female; Humans; Intestine, Large; Male; Metronidazole; Mezlocillin; Middle Aged; Premedication; Prospective Studies; Random Allocation; Rectum; Surgical Wound Infection

1987
A trial of mezlocillin versus cefuroxime with or without metronidazole for the prevention of wound sepsis after biliary and gastrointestinal surgery.
    The Journal of hospital infection, 1988, Volume: 12, Issue:3

    Topics: Biliary Tract Diseases; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Male; Metronidazole; Mezlocillin; Prospective Studies; Random Allocation; Surgical Wound Infection

1988
A prospective randomized trial to compare triple dose mezlocillin with triple dose cefuroxime plus metronidazole as prophylaxis in colorectal surgery.
    The Journal of hospital infection, 1988, Volume: 12, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Colonic Diseases; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Mezlocillin; Middle Aged; Premedication; Prospective Studies; Random Allocation; Rectal Diseases; Surgical Wound Infection

1988
[Bacteriological, clinical, and pharmacokinetic studies of perioperative antibiotic prophylaxis in head and neck surgery].
    Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. Serie B, Umwelthygiene, Krankenhaushygiene, Arbeitshygiene, praventive Medizin, 1987, Volume: 183, Issue:4

    Topics: Adult; Aged; Bacterial Infections; Female; Humans; Intraoperative Period; Laryngectomy; Male; Metronidazole; Mezlocillin; Middle Aged; Mouth; Mouth Neoplasms; Pharyngeal Neoplasms; Pharynx; Postoperative Complications; Premedication; Trachea; Tracheotomy

1987
Single-shot antibiotic prophylaxis in colon surgery.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Bacteria; Ceftizoxime; Clinical Trials as Topic; Colonic Neoplasms; Diverticulitis; Humans; Metronidazole; Mezlocillin; Moxalactam; Peritoneal Cavity; Postoperative Complications; Prospective Studies; Random Allocation; Rectal Neoplasms; Surgical Wound Infection; Urinary Tract Infections

1987
One versus three doses of metronidazole/mezlocillin for antibiotic prophylaxis in colon surgery.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Clinical Trials as Topic; Colonic Diseases; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Mezlocillin; Middle Aged; Postoperative Complications; Prospective Studies; Random Allocation; Surgical Wound Infection

1987
[Antibiotic treatment of perforated appendicitis in childhood--a prospective study].
    Zeitschrift fur Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft fur Kinderchirurgie = Surgery in infancy and childhood, 1986, Volume: 41, Issue:1

    Topics: Anti-Bacterial Agents; Appendectomy; Appendicitis; Child; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Female; Humans; Intestinal Perforation; Male; Metronidazole; Mezlocillin; Peritonitis; Premedication; Prospective Studies; Random Allocation; Rupture, Spontaneous; Sulfanilamides; Surgical Wound Infection; Trimethoprim

1986
[Antimicrobial chemoprevention in colorectal interventions: a single parenteral dose at the start of surgery is adequate].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1986, Volume: 57, Issue:6

    Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Bacterial Infections; Bacteriological Techniques; Colonic Diseases; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Metronidazole; Mezlocillin; Middle Aged; Neomycin; Premedication; Random Allocation; Rectal Diseases; Surgical Wound Infection

1986
A prospective randomized trial to compare mezlocillin and metronidazole with cefuroxime and metronidazole as prophylaxis in elective colorectal operations.
    The Journal of hospital infection, 1983, Volume: 4, Issue:4

    Topics: Adolescent; Adult; Aged; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Clostridium; Colon; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Mezlocillin; Middle Aged; Premedication; Pseudomonas aeruginosa; Random Allocation; Rectum; Surgical Wound Infection

1983
[Systemic mezlocillin prevention in elective colon surgery].
    Die Medizinische Welt, 1983, Sep-02, Volume: 34, Issue:35

    Topics: Aged; Clinical Trials as Topic; Colonic Diseases; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Mezlocillin; Middle Aged; Premedication; Surgical Wound Infection

1983
Prevention of post-appendicectomy sepsis by mezlocillin and metronidazole: a prospective, randomized, double-blind trial.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Appendectomy; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Metronidazole; Mezlocillin; Middle Aged; Premedication; Random Allocation; Surgical Wound Infection

1984
Audit of sepsis in operations for inflammatory bowel disease.
    Diseases of the colon and rectum, 1984, Volume: 27, Issue:9

    Topics: Abscess; Adult; Colitis, Ulcerative; Crohn Disease; Female; Gentamicins; Humans; Male; Metronidazole; Mezlocillin; Middle Aged; Moxalactam; Prospective Studies; Streptococcal Infections; Surgical Wound Infection

1984
[Modification of laparotomy wound healing in colon surgery by local antibiotic administration].
    Zentralblatt fur Chirurgie, 1996, Volume: 121 Suppl

    Topics: Antibiotic Prophylaxis; Colonic Diseases; Drug Implants; Drug Therapy, Combination; Gentamicins; Humans; Metronidazole; Mezlocillin; Prospective Studies; Surgical Wound Infection; Wound Healing

1996
Efficacy of oral ofloxacin for single-dose perioperative prophylaxis in general surgery--a controlled randomized clinical study.
    Langenbeck's archives of surgery, 2001, Volume: 386, Issue:6

    Topics: Administration, Oral; Anti-Infective Agents; Antibiotic Prophylaxis; Colon; Female; Humans; Injections, Intravenous; Male; Metronidazole; Mezlocillin; Middle Aged; Ofloxacin; Pancreas; Surgical Wound Infection

2001

Other Studies

21 other study(ies) available for mezlocillin and metronidazole

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Effect of daptomycin, metronidazole and mezlocillin combinations on mixed bacterial cultures involving facultative and anaerobic bacteria.
    Scandinavian journal of infectious diseases, 1991, Volume: 23, Issue:2

    Topics: Bacteriological Techniques; Bacteroides fragilis; Colony Count, Microbial; Daptomycin; Drug Therapy, Combination; Escherichia coli; Gram-Positive Bacteria; Metronidazole; Mezlocillin; Peptides

1991
Single dose mezlocillin versus three dose cefuroxime plus metronidazole for prophylaxis in large bowel surgery.
    The Journal of hospital infection, 1988, Volume: 12, Issue:2

    Topics: Cefotaxime; Colon; Drug Therapy, Combination; Humans; Infection Control; Metronidazole; Mezlocillin; Postoperative Complications

1988
Assessment of antimicrobial penetrance into the pancreatic juice in humans.
    Surgery, gynecology & obstetrics, 1986, Volume: 162, Issue:4

    Topics: Acute Disease; Cholangiopancreatography, Endoscopic Retrograde; Chromatography, High Pressure Liquid; Drug Combinations; Drug Evaluation; Humans; Metronidazole; Mezlocillin; Pancreatic Diseases; Pancreatic Ducts; Pancreatic Juice; Pancreatic Pseudocyst; Pancreatitis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Open study of different perioperative prophylactic regimens with mezlocillin/metronidazole in proctectomy.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Aged; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Mezlocillin; Postoperative Complications; Rectal Diseases

1987
[Bacteriologic findings and therapeutic consequences in adnexitis].
    Geburtshilfe und Frauenheilkunde, 1986, Volume: 46, Issue:7

    Topics: Adolescent; Adult; Aged; Bacteria; Bacterial Infections; Bacteriological Techniques; Drug Therapy, Combination; Female; Humans; Metronidazole; Mezlocillin; Microbial Sensitivity Tests; Middle Aged; Pelvic Inflammatory Disease

1986
Interactions of ciprofloxacin with clindamycin, metronidazole, cefoxitin, cefotaxime, and mezlocillin against gram-positive and gram-negative anaerobic bacteria.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:9

    Topics: Bacteria, Anaerobic; Cefotaxime; Cefoxitin; Ciprofloxacin; Drug Interactions; Drug Synergism; Gram-Negative Anaerobic Bacteria; Gram-Positive Bacteria; In Vitro Techniques; Metronidazole; Mezlocillin

1987
[Antibiotic prophylaxis in biliary surgery. Indications and results].
    Revista espanola de las enfermedades del aparato digestivo, 1985, Volume: 68, Issue:2

    Topics: Bacterial Infections; Biliary Tract Surgical Procedures; Cholecystitis; Cholestasis; Drug Administration Schedule; Female; Humans; Male; Metronidazole; Mezlocillin; Middle Aged; Postoperative Complications; Premedication

1985
Antibiotic therapy for anaerobic infections.
    American family physician, 1985, Volume: 31, Issue:4

    Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Bacteroides Infections; Carbenicillin; Cephalosporins; Chloramphenicol; Clindamycin; Humans; Metronidazole; Mezlocillin; Penicillin G; Ticarcillin

1985
Combination effect of mezlocillin plus metronidazole against enterococci, Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa and indole-positive proteus strains.
    Infection, 1982, Volume: 10, Issue:2

    Topics: Bacteria; Metronidazole; Mezlocillin; Microbial Sensitivity Tests; Penicillins

1982
[Antibiotic treatment of human actinomykoses (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1982, Aug-27, Volume: 107, Issue:34

    Topics: Actinomycosis; Ampicillin; Cefotaxime; Cefoxitin; Clindamycin; Metronidazole; Mezlocillin; Microbial Sensitivity Tests; Minocycline; Penicillin G; Penicillins

1982
Comparative efficacy of four antibiotics in anaerobic pulmonary infection. An experimental model in rabbits.
    Chemotherapy, 1984, Volume: 30, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; Bacteroides Infections; Cefoxitin; Eubacterium; Fusobacterium Infections; Male; Metronidazole; Mezlocillin; Microbial Sensitivity Tests; Moxalactam; Peptococcus; Pneumonia; Rabbits

1984
Surgical aspects in the management of peritonitis.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 100

    Topics: Aged; Aminoglycosides; Bacterial Infections; Cefoxitin; Drainage; Humans; Intraoperative Care; Isotonic Solutions; Metronidazole; Mezlocillin; Peritonitis; Postoperative Care; Ringer's Solution; Surgical Wound Infection; Therapeutic Irrigation

1984
[Surgical revision of the pilonidal sinus with single shot antibiosis].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1995, Volume: 66, Issue:3

    Topics: Abscess; Adult; Bacterial Infections; Drug Therapy, Combination; Humans; Infusions, Intravenous; Male; Metronidazole; Mezlocillin; Pilonidal Sinus; Postoperative Complications; Premedication; Recurrence; Sulbactam; Suture Techniques; Wound Healing

1995
In-vitro susceptibilities of species of the Bacteroides fragilis group to newer beta-lactam agents.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:1

    Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacteroides fragilis; beta-Lactamase Inhibitors; Cefoxitin; Ceftizoxime; Chloramphenicol; Clavulanic Acid; Clindamycin; Drug Therapy, Combination; Enzyme Inhibitors; Imipenem; Metronidazole; Mezlocillin; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Species Specificity; Sulbactam; Tazobactam; Thienamycins; Ticarcillin

1999
Pharmacokinetic basis for oral perioperative prophylaxis with ofloxacin in general surgery.
    Infection, 2001, Volume: 29, Issue:4

    Topics: Administration, Oral; Anti-Infective Agents; Antibiotic Prophylaxis; Humans; Injections, Intravenous; Metronidazole; Mezlocillin; Ofloxacin; Penicillins; Preoperative Care; Risk Factors; Treatment Outcome

2001
Comparative study of mezlocillin in combination with metronidazole in patients with perforation of the inflamed appendix.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Anti-Infective Agents; Appendectomy; Appendicitis; Bacteria; Bacterial Infections; Controlled Clinical Trials as Topic; Humans; Metronidazole; Mezlocillin; Peritonitis; Surgical Wound Infection

1989
Optimal timing for antimicrobial prophylaxis to reduce surgical site infections: a retrospective analysis of 531 patients.
    Scientific reports, 2023, 06-09, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Cefuroxime; Colorectal Neoplasms; Humans; Metronidazole; Mezlocillin; Piperacillin; Retrospective Studies; Sulbactam; Surgical Wound Infection; Tazobactam

2023