mexiprostil has been researched along with alprostadil in 12 studies
| Studies (mexiprostil) | Trials (mexiprostil) | Recent Studies (post-2010) (mexiprostil) | Studies (alprostadil) | Trials (alprostadil) | Recent Studies (post-2010) (alprostadil) |
|---|---|---|---|---|---|
| 13 | 4 | 0 | 7,136 | 864 | 761 |
| Protein | Taxonomy | mexiprostil (IC50) | alprostadil (IC50) |
|---|---|---|---|
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 2.3 | |
| Solute carrier organic anion transporter family member 2B1 | Rattus norvegicus (Norway rat) | 0.0358 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (91.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hall, TJ; Heckel, C | 1 |
| Dammann, HG; Leucht, U; Müller, P; Simon, B | 1 |
| Ciabatti, R; Padova, G; Pelizzi, G; Tarzia, G | 1 |
| Bianchi Porro, G; Fuccella, L; Lazzaroni, M; Petrillo, M; Sassella, D | 1 |
| Dammann, HG; Müller, P; Simon, B | 1 |
| Battaglia, F; Cellentani, M; Ciabatti, R; Depaoli, A; Galliani, G; Guzzi, U; Padova, G; Schiatti, P; Spina, G | 1 |
| Coruzzi, G; Poli, E | 1 |
| Gallico, L; Glässer, A; Schiatti, P; Selva, D; Spina, G | 1 |
| Bertaccini, G; Scarpignato, C; Signorini, GC; Spina, G | 1 |
| Ciabatti, R; Colombo, G; Galliani, G; Glässer, A; Guzzi, U; Luzzani, F | 1 |
| Adami, M; Bertaccini, G; Coruzzi, G; Glässer, A; Poli, E | 1 |
| Bardoni, A; Castellani, AA; Glässer, A; Pallavicini, G; Profumo, A; Schiatti, P | 1 |
3 trial(s) available for mexiprostil and alprostadil
| Article | Year |
|---|---|
An alprostadil analogue and human gastric secretion. A double-blind placebo-controlled study of the effects of a capsule and tablet formulation.
Topics: Adult; Alprostadil; Anti-Ulcer Agents; Capsules; Double-Blind Method; Gastric Acid; Gastric Mucosa; Humans; Male; Pentagastrin; Placebos; Prostaglandins E, Synthetic; Tablets; Time Factors | 1989 |
Gastric antisecretory and cytoprotective activity of MDL 646, a 16-methyl-16-methoxy prostaglandin E1 analog in man.
Topics: Administration, Oral; Adult; Aged; Alprostadil; Anti-Ulcer Agents; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Humans; Male; Middle Aged; Prostaglandins E, Synthetic | 1987 |
An alprostadil analogue and human gastric secretion. A double-blind placebo-controlled study of the effects of a tablet and lyovial formulation.
Topics: Adult; Alprostadil; Anti-Ulcer Agents; Double-Blind Method; Gastric Acid; Gastric Mucosa; Humans; Male; Pentagastrin; Prostaglandins E, Synthetic; Tablets | 1987 |
9 other study(ies) available for mexiprostil and alprostadil
| Article | Year |
|---|---|
Lack of effect of verapamil and MDL 646, a cytoprotective PGE1 analogue on cyclosporin A nephrotoxicity in vitro.
Topics: Alprostadil; Animals; Anti-Ulcer Agents; Cattle; Cell Division; Cells, Cultured; Cyclosporins; Kidney Diseases; Prostaglandins E, Synthetic; Swine; Verapamil | 1990 |
X-ray structure determination of mexiprostil, a new gastroprotective 16-methoxy-16-methyl-PGE1 analogue.
Topics: Alprostadil; Anti-Ulcer Agents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Prostaglandins E, Synthetic; X-Ray Diffraction | 1988 |
Structure-activity studies of 16-methoxy-16-methyl prostaglandins.
Topics: Alprostadil; Antidiarrheals; Fertility; Gastric Acid; Molecular Conformation; Prostaglandins E, Synthetic; Prostaglandins F, Synthetic; Structure-Activity Relationship | 1986 |
[Action of a new synthetic prostaglandin on gastroesophageal motility of the rat].
Topics: Alprostadil; Animals; Gastrointestinal Motility; In Vitro Techniques; Prostaglandins E; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1982 |
MDL-646, a new synthetic E1-prostaglandin with local protective effects on the gastric mucosa.
Topics: Alprostadil; Animals; Anti-Ulcer Agents; Blood Pressure; Ethanol; Gastric Juice; Gastric Mucosa; Heart Rate; Indomethacin; Male; Prostaglandins E; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Stomach Ulcer | 1984 |
Action of MDL 646, a new synthetic prostaglandin, on gastric acid secretion of some experimental animals.
Topics: Alprostadil; Animals; Bethanechol Compounds; Cats; Chemical Phenomena; Chemistry; Depression, Chemical; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Gastric Acid; Gastric Acidity Determination; Histamine; Pentagastrin; Prostaglandins E; Prostaglandins E, Synthetic; Rats; Species Specificity | 1983 |
Studies on the luteolytic activity of MDL-646, a new gastroprotective PGE1 analogue, in the hamster.
Topics: Abortion, Spontaneous; Alprostadil; Animals; Anti-Ulcer Agents; Corpus Luteum; Cricetinae; Dinoprostone; Female; Mesocricetus; Pregnancy; Progesterone; Prostaglandins E; Prostaglandins E, Synthetic; Structure-Activity Relationship | 1984 |
Effect of MDL 646, a new synthetic prostaglandin, on gastroesophageal motility of the rat.
Topics: Alprostadil; Animals; Esophagogastric Junction; Esophagus; Female; Gastrointestinal Motility; Prostaglandins E; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Stomach | 1983 |
Protection of rat gastric mucosa against ethanol injury by the new synthetic prostaglandin MDL 646.
Topics: Alprostadil; Animals; Anti-Ulcer Agents; Ethanol; Gastric Mucosa; Glycoproteins; Male; Necrosis; Prostaglandins E, Synthetic; Proteins; Rats; Rats, Inbred Strains; Stomach Diseases | 1984 |