mexiletine and ouabain

mexiletine has been researched along with ouabain in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's3 (27.27)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campillo, NE; Guerra, A; Páez, JA1
Bigger, JT; Bordiuk, J; Lau, YH; Swistel, D; Weld, FM1
Fukami, M; Hashimoto, T; Itoh, Y; Koike, H; Kumakura, S; Miyake, S; Mizuno, H; Shiga, H; Shimoji, Y; Yorikane, R1
Jaszlits, L; Kürthy, M; Rabloczky, G; Toldy, L; Varró, A; Zubovics, Z1
Sakai, K; Takagi, M; Yamazaki, T1
Gasparík, J; Hesek, D; Hudcovicová, E; Jezek, L; Mahrla, Z; Nosál, R; Rybár, A; Urbánková, G1
Kitagawa, H; Kohei, H; Takeda, F1
Almotrefi, AA; Baker, JB1
Benes, L; Cernusková, L; Csöllei, J; Svec, P; Tumová, I1
Awaji, T; Hashimoto, K1
Hideg, K; Kalai, T; Kuppusamy, P; Li, H; Xu, KY; Zhou, L; Zweier, JL1

Other Studies

11 other study(ies) available for mexiletine and ouabain

ArticleYear
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Electrophysiological effects of mexiletine (Kö1173) on ovine cardiac Purkinje fibers.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 210, Issue:2

    Topics: Action Potentials; Animals; Cardiac Pacing, Artificial; Cattle; Heart Conduction System; In Vitro Techniques; Mexiletine; Ouabain; Propylamines; Purkinje Fibers; Sheep; Time Factors

1979
Antiarrhythmic and cardiovascular profiles of the fused indole compound (3aR,12R,12aR,12bS)-12-amino-2,3,3a,4,11,12,12a,12b-octahydro-10-hydrox yisoquino [2,1,8-lma]carbazol-5(1H)-one hydrochloride 1.5 hydrate.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:11

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbazoles; Chloroform; Disopyramide; Dogs; Female; Flecainide; Heart; Heart Conduction System; Hemodynamics; Isoquinolines; Lidocaine; Male; Mexiletine; Mice; Mice, Inbred ICR; Myocardial Contraction; Ouabain

1991
Pharmacological investigation of a new anti-arrhythmic agent, GYKI-23 107.
    Drugs under experimental and clinical research, 1987, Volume: 13, Issue:1

    Topics: Aconitum; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Chemical Phenomena; Chemistry; Dogs; Female; Hemodynamics; Lidocaine; Male; Mexiletine; Mice; Ouabain; Propylamines; Rats

1987
Antiarrhythmic effects of a novel diamine derivative, AN-132, on several animal models of cardiac arrhythmias.
    The Tohoku journal of experimental medicine, 1987, Volume: 151, Issue:4

    Topics: Aconitine; Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chloroform; Disopyramide; Dogs; Epinephrine; Ethylenediamines; Female; Guinea Pigs; Halothane; Male; Mexiletine; Ouabain; Propafenone; Rats; Rats, Inbred Strains

1987
[Preclinical study of the pharmacodynamic and toxicologic effects of the antiarrhythmic agent, mexiletine].
    Bratislavske lekarske listy, 1986, Volume: 85, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Dogs; Female; Guinea Pigs; Heart Rate; Lethal Dose 50; Male; Mexiletine; Mice; Ouabain; Propylamines

1986
Inhibition of sympathetic nervous system by mexiletine, an antiarrhythmic agent, and its antagonism against ouabain.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:1A

    Topics: Animals; Aorta, Thoracic; Arrhythmias, Cardiac; Electric Stimulation; Epinephrine; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Mexiletine; Muscle Contraction; Muscle, Smooth, Vascular; Nicotine; Norepinephrine; Ouabain; Portal Vein; Potassium Chloride; Propylamines; Pulmonary Artery; Rabbits; Rats; Rats, Inbred Strains; Sympatholytics; Tyramine

1985
The antifibrillatory potency of aprindine, mexiletine, tocainide and lignocaine compared on Langendorff-perfused hearts of rabbits and guinea-pigs.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:11

    Topics: Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart; In Vitro Techniques; Indenes; Lidocaine; Male; Mexiletine; Ouabain; Perfusion; Propylamines; Rabbits; Tocainide; Ventricular Fibrillation

1980
Carbamate analogues of tocainide.
    Die Pharmazie, 1994, Volume: 49, Issue:9

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Carbamates; Cardiac Complexes, Premature; Epinephrine; Guinea Pigs; Mexiletine; Ouabain; Rats; Tocainide

1994
Antiarrhythmic effects of combined application of class I antiarrhythmic drugs; addition of low-dose mexiletine-enhanced antiarrhythmic effects of disopyramide and aprindine in various-rate canine ventricular tachycardias.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Blood Pressure; Coronary Vessels; Disopyramide; Dogs; Drug Interactions; Drug Synergism; Electrophysiology; Female; Heart Rate; Infusions, Intravenous; Male; Mexiletine; Ouabain; Tachycardia, Ventricular

1993
A pyrroline derivative of mexiletine offers marked protection against ischemia/reperfusion-induced myocardial contractile dysfunction.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Binding, Competitive; Coronary Circulation; Dose-Response Relationship, Drug; Female; Hydroxyl Radical; Mexiletine; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Ouabain; Oxidation-Reduction; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Ventricular Dysfunction, Left; Ventricular Pressure

2000