Page last updated: 2024-08-24

mevastatin and y 27632

mevastatin has been researched along with y 27632 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Bertoglio, J; Blaie, S; Bolla, M; Boquet, P; Créminon, C; Degraeve, F; Habib, A; Lévy-Toledano, S; Quéré, I1
Corey, DA; Elmer, HL; Kelley, TJ; Kraynack, NC1
Budzyn, K; Marley, PD; Sobey, CG1
Goez, P; Hagelgans, A; Hempel, U; Heyne, B; Jaross, W; Menschikowski, M; Neumeister, V; Siegert, G1
Betta, PG; Bosia, A; Ghigo, D; Orecchia, S; Pescarmona, G; Riganti, C1
Aldieri, E; Betta, PG; Bosia, A; Gazzano, E; Ghigo, D; Orecchia, S; Pescarmona, G; Riganti, C; Silvagno, F1

Other Studies

7 other study(ies) available for mevastatin and y 27632

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins.
    The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50

    Topics: Amides; Aorta; Apoptosis; Bacterial Proteins; Bacterial Toxins; Blotting, Northern; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Dactinomycin; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoprostenol; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inhibitory Concentration 50; Interleukin-1; Isoenzymes; Leucine; Lovastatin; Membrane Proteins; Mevalonic Acid; Muscle, Smooth; Nucleic Acid Synthesis Inhibitors; Prostaglandin-Endoperoxide Synthases; Protein Prenylation; Pyridines; rho GTP-Binding Proteins; Time Factors

2001
Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 283, Issue:3

    Topics: Amides; Dimethylallyltranstransferase; Enzyme Inhibitors; Epithelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Lovastatin; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Pulmonary Alveoli; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger; Signal Transduction; Transcription Factor AP-1; Tumor Cells, Cultured

2002
Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 287, Issue:2

    Topics: Amides; Animals; Anticholesteremic Agents; Aorta, Thoracic; Cholesterol; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Lovastatin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Vasoconstriction

2004
Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells.
    Biochimica et biophysica acta, 2005, Apr-15, Volume: 1733, Issue:2-3

    Topics: Amides; Aorta; Atorvastatin; Bacterial Proteins; Bacterial Toxins; Butadienes; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Drug Synergism; Flavonoids; Group II Phospholipases A2; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Janus Kinase 2; Lovastatin; Myocytes, Smooth Muscle; NF-kappa B; Nitriles; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyridines; Pyrroles; RNA Stability; Up-Regulation

2005
Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma.
    International journal of cancer, 2006, Jul-01, Volume: 119, Issue:1

    Topics: Amides; Antibiotics, Antineoplastic; Bacterial Proteins; Bacterial Toxins; Blotting, Western; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mesothelioma; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Pyridines; Simvastatin

2006
Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition.
    American journal of respiratory cell and molecular biology, 2007, Volume: 36, Issue:6

    Topics: Active Transport, Cell Nucleus; Amides; Animals; Asbestos, Crocidolite; Cattle; Cell Line, Tumor; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Humans; I-kappa B Kinase; Isoenzymes; Lovastatin; Mesothelioma; Mevalonic Acid; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Proto-Oncogene Proteins c-akt; Pyridines; rho GTP-Binding Proteins; Second Messenger Systems; Terpenes

2007