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mevastatin and phenyl acetate

mevastatin has been researched along with phenyl acetate in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199015 (71.43)18.7374
1990's4 (19.05)18.2507
2000's2 (9.52)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Endo, A; Hazama-Shimada, Y; Kaneko, I1
Endo, A; Kuroda, M; Tanzawa, K; Tsujita, Y1
Bradfute, DL; Silva, CJ; Simoni, RD1
Gebhardt, R1
Hasegawa, K; Koga, T; Kuroda, M; Shimada, Y; Tsujita, Y; Yamazaki, M1
Buddecke, E; Filipovic, I1
Kumagai, H; Omura, S; Tanaka, H; Tomoda, H1
Mason, JI; Rainey, WE1
BaraƱao, JL; Hammond, JM1
Knight, BL; Patel, DD; Soutar, AK1
Astrand, IM; Chojnacki, T; Dallner, G; Fries, E1
Hatton, J; Middleton, B; White, DA1
Golomb, HM; Saffold, C; West, EJ; Yachnin, S1
Glomset, JA; Habenicht, AJ; Ross, R1
Hoffman, PC; Larson, RA; Richman, CM; Yachnin, S1
Astruc, M; Crastes de Paulet, A; Defay, R; Descomps, B; Roussillon, S1
Akiyama, S; Kuwano, M; Masuda, A1
Nambudiri, AM; Ranganathan, S; Rudney, H1
Michikawa, M; Yanagisawa, K1
Bai, F; Bencharit, S; Edwards, CC; Fleming, CD; Fraga, C; Howard-Williams, EL; Hyatt, JL; Morton, CL; Potter, PM; Redinbo, MR; Tsurkan, L1
Kim, J; Matsuyama, S; Suzuki, T1

Other Studies

21 other study(ies) available for mevastatin and phenyl acetate

ArticleYear
Inhibitory effects on lipid metabolism in cultured cells of ML-236B, a potent inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase.
    European journal of biochemistry, 1978, Jun-15, Volume: 87, Issue:2

    Topics: Acetates; Cells, Cultured; DNA; Fibroblasts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; L Cells; Lipid Metabolism; Lovastatin; Naphthalenes; Oleic Acids; Protein Biosynthesis; RNA; Skin

1978
Inhibition of cholesterol synthesis in vitro and in vivo by ML-236A and ML-236B, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    European journal of biochemistry, 1977, Jul-01, Volume: 77, Issue:1

    Topics: Acetates; Animals; Binding, Competitive; Caprylates; Cholesterol; Fatty Acids; Gallbladder; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Kidney; Kinetics; Lactones; Liver; Lovastatin; Male; Mevalonic Acid; Mice; Naphthalenes; Naphthols; Organ Specificity; Pyrans; Rats; Sterols

1977
Squalene synthase-deficient mutant of Chinese hamster ovary cells.
    The Journal of biological chemistry, 1992, Sep-15, Volume: 267, Issue:26

    Topics: Acetates; Animals; CHO Cells; Cholesterol; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cricetinae; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Flow Cytometry; Hydroxymethylglutaryl CoA Reductases; Lovastatin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mevalonic Acid; Mutagenesis

1992
Inhibition of cholesterol biosynthesis by a water-soluble garlic extract in primary cultures of rat hepatocytes.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:8

    Topics: Acetates; Animals; Anticholesteremic Agents; Cell Survival; Cells, Cultured; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Fatty Acid Synthases; Garlic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Liver; Lovastatin; Male; Mevalonic Acid; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Sterol O-Acyltransferase

1991
Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
    Biochimica et biophysica acta, 1990, Jul-16, Volume: 1045, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Anticholesteremic Agents; Cells, Cultured; Cholesterol; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileum; Kinetics; L Cells; Lens, Crystalline; Liver; Lovastatin; Male; Mice; Mice, Inbred C57BL; Naphthalenes; Pravastatin; Rats; Simvastatin; Spleen

1990
Calmodulin antagonists stimulate LDL receptor synthesis in human skin fibroblasts.
    Biochimica et biophysica acta, 1986, Mar-21, Volume: 876, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Acetates; Acetic Acid; Androstenes; Calcium Chloride; Calmodulin; Cholera Toxin; Cholesterol; Cyclic AMP; Fibroblasts; Humans; Hydroxycholesterols; Lovastatin; Methionine; Mevalonic Acid; Molecular Weight; Naphthalenes; p-Methoxy-N-methylphenethylamine; Receptors, LDL; Skin; Sulfonamides; Trifluoperazine

1986
F-244 specifically inhibits 3-hydroxy-3-methylglutaryl coenzyme A synthase.
    Biochimica et biophysica acta, 1987, Dec-14, Volume: 922, Issue:3

    Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Acetyl-CoA C-Acetyltransferase; Animals; Carbohydrate Sequence; Cell Line; Fatty Acids, Unsaturated; Hydroxymethylglutaryl-CoA Synthase; Lactones; Liver; Lovastatin; Mevalonic Acid; Oxo-Acid-Lyases; Rats; Sterols

1987
Steroidogenesis in the human fetal adrenal: a role for cholesterol synthesized de novo.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 64, Issue:1

    Topics: Acetates; Adrenal Glands; Adrenocorticotropic Hormone; Androstenedione; Cells, Cultured; Cholesterol; Culture Media; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxymethylglutaryl CoA Reductases; Lipoproteins; Lovastatin; Naphthalenes

1987
FSH increases the synthesis and stores of cholesterol in porcine granulosa cells.
    Molecular and cellular endocrinology, 1986, Volume: 44, Issue:3

    Topics: Acetates; Animals; Cell Division; Cells, Cultured; Cholesterol; Female; Follicle Stimulating Hormone; Granulosa Cells; Intracellular Fluid; Lovastatin; Naphthalenes; Progesterone; Swine; Time Factors

1986
Regulation of synthesis and cell content of the low-density-lipoprotein receptor protein in cultured fibroblasts from normal and familial hypercholesterolaemic subjects.
    European journal of biochemistry, 1987, Feb-16, Volume: 163, Issue:1

    Topics: Acetates; Cell Membrane; Cells, Cultured; Cholesterol; Fibroblasts; Humans; Hyperlipoproteinemia Type II; Immunochemistry; Lipoproteins; Lovastatin; Methionine; Naphthalenes; Radioimmunoassay; Receptors, LDL

1987
Inhibition of dolichyl phosphate biosynthesis by compactin in cultured rat hepatocytes.
    European journal of biochemistry, 1986, Mar-03, Volume: 155, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Cells, Cultured; Cholesterol; Cytidine Triphosphate; Dolichol Phosphates; Glycerol; Leucine; Liver; Lovastatin; Male; Naphthalenes; Phospholipids; Phosphorus Radioisotopes; Phosphorylation; Polyisoprenyl Phosphates; Protein Biosynthesis; Rats; Tritium

1986
A mevalonate requirement for maintenance of fatty acid and protein synthesis during hormonally stimulated development of mammary gland in vitro.
    The Journal of biological chemistry, 1984, Aug-25, Volume: 259, Issue:16

    Topics: Acetates; Acetic Acid; Animals; Carbon Radioisotopes; Fatty Acids; Female; Hydroxymethylglutaryl CoA Reductases; Insulin; Leucine; Lovastatin; Mammary Glands, Animal; Mevalonic Acid; Microsomes; Naphthalenes; Organ Culture Techniques; Pregnancy; Prolactin; Protein Biosynthesis; Rabbits; Tritium

1984
Increased cholesterol biosynthesis in leukemic cells from patients with hairy cell leukemia.
    Blood, 1983, Volume: 61, Issue:1

    Topics: Acetates; Adult; B-Lymphocytes; Cells, Cultured; Cholesterol; Concanavalin A; DNA; Female; Humans; Hydroxycholesterols; Leukemia, Hairy Cell; Lovastatin; Male; Mevalonic Acid; Middle Aged; Naphthalenes

1983
Relation of cholesterol and mevalonic acid to the cell cycle in smooth muscle and swiss 3T3 cells stimulated to divide by platelet-derived growth factor.
    The Journal of biological chemistry, 1980, Jun-10, Volume: 255, Issue:11

    Topics: Acetates; Animals; Cell Cycle; Cell Line; Cells, Cultured; Cholesterol; DNA; Growth Substances; Haplorhini; Hydroxycholesterols; Kinetics; Lovastatin; Macaca; Mevalonic Acid; Mice; Mitogens; Muscle, Smooth, Vascular; Naphthalenes; Platelet-Derived Growth Factor; Thymidine

1980
Cholesterol and mevalonic acid are independent requirements for the in vitro proliferation of human bone marrow granulocyte progenitor cells: studies using ML-236B.
    Blood, 1983, Volume: 61, Issue:4

    Topics: Acetates; Cell Division; Cholesterol; DNA; Hematopoietic Stem Cells; Humans; Hydroxycholesterols; Lovastatin; Mevalonic Acid; Naphthalenes; Optical Rotation

1983
DNA and cholesterol biosynthesis in synchronized embryonic rat fibroblasts. II. Effects of sterol biosynthesis inhibitors on cell division.
    Biochimica et biophysica acta, 1983, Aug-17, Volume: 763, Issue:1

    Topics: Acetates; Animals; Cell Cycle; Cells, Cultured; Cholesterol; DNA Replication; Embryo, Mammalian; Fibroblasts; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lovastatin; Naphthalenes; Rats; Thymidine

1983
Chinese hamster cell mutant resistant to ML236B (Compactin) is defective in endocytosis of low-density lipo-protein.
    Molecular and cellular biology, 1982, Volume: 2, Issue:11

    Topics: Acetates; Animals; Cell Line; Clone Cells; Cricetinae; Drug Resistance; Endocytosis; Genes, Regulator; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Ketocholesterols; Lipoproteins, LDL; Lovastatin; Mevalonic Acid; Mutation; Naphthalenes; Sterols

1982
The regulation of ubiquinone synthesis in fibroblasts: the effect of modulators of beta-hydroxy-beta-methylglutaryl-coenzyme A reductase activity.
    Archives of biochemistry and biophysics, 1981, Volume: 210, Issue:2

    Topics: Acetates; Cell Line; Culture Media; Fibroblasts; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Lovastatin; Naphthalenes; Ubiquinone

1981
Inhibition of cholesterol production but not of nonsterol isoprenoid products induces neuronal cell death.
    Journal of neurochemistry, 1999, Volume: 72, Issue:6

    Topics: 3T3 Cells; Acetates; Animals; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Survival; Cerebral Cortex; Cholesterol; Embryo, Mammalian; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lipoproteins, VLDL; Lovastatin; Mevalonic Acid; Mice; Neurons; PC12 Cells; Rabbits; Rats; Rats, Sprague-Dawley; Squalene; Tricarboxylic Acids

1999
Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.
    Journal of molecular biology, 2005, Sep-09, Volume: 352, Issue:1

    Topics: Acetates; Anticholesteremic Agents; Antineoplastic Agents, Hormonal; Carboxylic Ester Hydrolases; Crystallography, X-Ray; Humans; Lovastatin; Models, Molecular; Molecular Sequence Data; Molecular Structure; Phenylglyoxal; Protein Structure, Quaternary; Substrate Specificity; Tamoxifen

2005
4,8-Dimethyldecanal, the aggregation pheromone of Tribolium castaneum, is biosynthesized through the fatty acid pathway.
    Journal of chemical ecology, 2005, Volume: 31, Issue:6

    Topics: Acetates; Aldehydes; Animals; Carbon Radioisotopes; Deuterium; Esters; Fatty Acids; Fatty Acids, Monounsaturated; Gas Chromatography-Mass Spectrometry; Isotope Labeling; Lovastatin; Male; Mevalonic Acid; Pheromones; Propionates; Sesquiterpenes; Tribolium; Volatilization

2005