Page last updated: 2024-08-24

mevastatin and atorvastatin

mevastatin has been researched along with atorvastatin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (70.59)29.6817
2010's4 (23.53)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Aparna, V; Chakraborti, AK; Gopalakrishnan, B; Kumar, R; Sobhia, ME; Thilagavathi, R1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Baret, E; Briolant, S; Fontaine, A; Fusai, T; Henry, M; Mosnier, J; Pradines, B; Rogier, C; Torrentino-Madamet, M1
Egbert, M; Keserű, GM; Vajda, S; Whitty, A1
Hamakubo, T; Inoue, K; Kitahara, M; Kodama, T; Morikawa, S; Nakagawa, S; Saito, Y; Suganami, H; Umetani, M; Yamazaki, H1
Edvinsson, L; Stenman, E; Xu, CB1
Aicher, A; Assmus, B; Dimmeler, S; Haendeler, J; Hofmann, WK; Rössig, L; Spyridopoulos, I; Urbich, C; Zeiher, AM1
Bernier, L; Chamberland, A; Davignon, J; Dubuc, G; Prat, A; Seidah, NG; Wassef, H1
Dimmeler, S; Haendeler, J; Hoffmann, J; Zeiher, AM1
Brummendorf, TH; Dimmeler, S; Haendeler, J; Oh, H; Schneider, MD; Spyridopoulos, I; Urbich, C; Zeiher, AM1
Goez, P; Hagelgans, A; Hempel, U; Heyne, B; Jaross, W; Menschikowski, M; Neumeister, V; Siegert, G1
Crespo, MJ; Quidgley, JA1
George, J; Keren, G; Luboshits, G; Mausner-Fainberg, K; Maysel-Auslender, S; Mor, A; Rubinstein, A1
Tuğlu, MI; Vural, K1
Bosch, J; García-Cardeña, G; García-Pagán, JC; Gracia-Sancho, J; Hide, D; Marrone, G; Rosado, E; Russo, L1
Bai, Y; Chan, C; Chang, X; Cheng, N; Cheng, Z; Lu, Y; Zhao, Y1
Abderrahmani, A; Andrew, T; Boutry, R; Canouil, M; Crouch, H; Froguel, P; Khamis, A; Lobbens, S; Mathew, S; Tamanini, F1

Reviews

1 review(s) available for mevastatin and atorvastatin

ArticleYear
Efficacy and safety of long-term treatment with statins for coronary heart disease: A Bayesian network meta-analysis.
    Atherosclerosis, 2016, Volume: 254

    Topics: Anticholesteremic Agents; Atorvastatin; Bayes Theorem; Coronary Disease; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Kidney Diseases; Lipids; Lovastatin; Muscles; Network Meta-Analysis; Patient Safety; Pravastatin; Quinolines; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome

2016

Other Studies

16 other study(ies) available for mevastatin and atorvastatin

ArticleYear
Three-dimensional quantitative structure (3-D QSAR) activity relationship studies on imidazolyl and N-pyrrolyl heptenoates as 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) inhibitors by comparative molecular similarity indices analysis (CoMSIA).
    Bioorganic & medicinal chemistry letters, 2005, Feb-15, Volume: 15, Issue:4

    Topics: Binding Sites; Crystallography, X-Ray; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Inhibitory Concentration 50; Models, Molecular; Protein Conformation; Pyrroles; Quantitative Structure-Activity Relationship

2005
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Atorvastatin is 10-fold more active in vitro than other statins against Plasmodium falciparum.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Animals; Antimalarials; Atorvastatin; Dose-Response Relationship, Drug; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Inhibitory Concentration 50; Malaria, Falciparum; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrroles; Structure-Activity Relationship

2007
Why Some Targets Benefit from beyond Rule of Five Drugs.
    Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22

    Topics: Binding Sites; Drug Discovery; Ligands; Molecular Weight; Protein Binding

2019
Relative induction of mRNA for HMG CoA reductase and LDL receptor by five different HMG-CoA reductase inhibitors in cultured human cells.
    Journal of atherosclerosis and thrombosis, 2000, Volume: 7, Issue:3

    Topics: Atorvastatin; Cell Line; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lovastatin; Pravastatin; Pyrroles; Quinolines; Receptors, LDL; RNA, Messenger; Simvastatin

2000
Reduction of bFGF-induced smooth muscle cell proliferation and endothelin receptor mRNA expression by mevastatin and atorvastatin.
    Biochemical pharmacology, 2002, Aug-01, Volume: 64, Issue:3

    Topics: Animals; Anticholesteremic Agents; Aorta; Atorvastatin; Cell Division; Cerebral Arteries; Drug Interactions; Endothelin Receptor Antagonists; Fibroblast Growth Factor 2; Heptanoic Acids; Lovastatin; Male; Muscle, Smooth; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors

2002
HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes.
    Circulation research, 2003, May-16, Volume: 92, Issue:9

    Topics: Atorvastatin; Cell Cycle Proteins; Cell Division; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Endothelium, Vascular; Gene Expression Profiling; Gene Expression Regulation; Genes, cdc; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukocytes, Mononuclear; Lovastatin; Oligonucleotide Array Sequence Analysis; Pyrroles; Signal Transduction; Stem Cells; Telomerase; Tumor Suppressor Proteins

2003
Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:8

    Topics: Alitretinoin; Animals; Atorvastatin; Base Sequence; Cell Line; Cholesterol; Consensus Sequence; DNA-Binding Proteins; Gene Expression Regulation; Hepatocytes; Heptanoic Acids; Homeostasis; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver X Receptors; Lovastatin; Mevalonic Acid; Mice; Orphan Nuclear Receptors; Promoter Regions, Genetic; Proprotein Convertase 9; Proprotein Convertases; Pyridines; Pyrroles; Quinolines; Rats; Receptors, Cytoplasmic and Nuclear; Regulatory Sequences, Nucleic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sequence Homology, Nucleic Acid; Serine Endopeptidases; Simvastatin; Sp1 Transcription Factor; Species Specificity; Sterol Regulatory Element Binding Protein 2; Transcription Factors; Tretinoin

2004
Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins.
    Circulation, 2004, Aug-17, Volume: 110, Issue:7

    Topics: Amino Acid Substitution; Antioxidants; Atorvastatin; Cells, Cultured; Cysteine; Endothelial Cells; Endothelium, Vascular; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mutagenesis, Site-Directed; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Pyrroles; Reactive Oxygen Species; Recombinant Fusion Proteins; S-Nitrosothiols; Simvastatin; Thioredoxins; Transfection; Umbilical Veins

2004
Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.
    Circulation, 2004, Nov-09, Volume: 110, Issue:19

    Topics: Adenoviridae; Amino Acid Sequence; Atorvastatin; Cell Movement; Cells, Cultured; Cellular Senescence; Checkpoint Kinase 2; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Flow Cytometry; Genetic Vectors; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Situ Hybridization, Fluorescence; Interleukin-4; Lovastatin; Macrophage Colony-Stimulating Factor; Molecular Sequence Data; Protein Serine-Threonine Kinases; Pyrroles; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Telomere; Telomeric Repeat Binding Protein 2; Vascular Endothelial Growth Factor A

2004
Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells.
    Biochimica et biophysica acta, 2005, Apr-15, Volume: 1733, Issue:2-3

    Topics: Amides; Aorta; Atorvastatin; Bacterial Proteins; Bacterial Toxins; Butadienes; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Drug Synergism; Flavonoids; Group II Phospholipases A2; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Janus Kinase 2; Lovastatin; Myocytes, Smooth Muscle; NF-kappa B; Nitriles; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyridines; Pyrroles; RNA Stability; Up-Regulation

2005
Statins decrease serotonin-induced contractions in coronary arteries of swine in vitro.
    Pharmacology, 2006, Volume: 76, Issue:3

    Topics: Animals; Atorvastatin; Coronary Vessels; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lovastatin; Male; Pravastatin; Pyrroles; Serotonin; Simvastatin; Swine; Time Factors; Vasoconstriction

2006
The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells.
    Atherosclerosis, 2008, Volume: 197, Issue:2

    Topics: Adult; Animals; Atorvastatin; Forkhead Transcription Factors; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Mice; Mice, Inbred C57BL; Pravastatin; Pyrroles; T-Lymphocytes, Regulatory; Up-Regulation

2008
Neurotoxic effect of statins on mouse neuroblastoma NB2a cell line.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:9

    Topics: Animals; Atorvastatin; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Neurites; Neuroblastoma; Pyrroles

2011
The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial-stellate cell deactivation induced by statins.
    Journal of hepatology, 2013, Volume: 58, Issue:1

    Topics: Animals; Atorvastatin; Cell Communication; Disease Models, Animal; Endothelial Cells; Gene Expression; Hepatic Stellate Cells; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Kruppel-Like Transcription Factors; Liver; Liver Circulation; Liver Cirrhosis, Experimental; Lovastatin; Male; Paracrine Communication; Pyrroles; Rats; Rats, Wistar; Simvastatin; Stress, Mechanical

2013
Histone deacetylase 9 promoter hypomethylation associated with adipocyte dysfunction is a statin-related metabolic effect.
    Clinical epigenetics, 2020, 05-14, Volume: 12, Issue:1

    Topics: Adipogenesis; Atorvastatin; ATP Binding Cassette Transporter, Subfamily G, Member 1; Cell Line; DNA Methylation; Epigenesis, Genetic; Histone Deacetylases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Lovastatin; Promoter Regions, Genetic; Repressor Proteins; Stem Cells

2020