mevalonic acid and 3,3-dimethylallyl pyrophosphate

mevalonic acid has been researched along with 3,3-dimethylallyl pyrophosphate in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.00)18.7374
1990's2 (8.00)18.2507
2000's7 (28.00)29.6817
2010's10 (40.00)24.3611
2020's4 (16.00)2.80

Authors

AuthorsStudies
Deneris, ES; Mead, JF; Stein, RA2
Knani, M; Rohmer, M; Sahm, H; Simonin, P; Sutter, B1
Fliesler, SJ; Keller, RK1
Boronat, A; Campos, N; Grosdemange-Billiard, C; Hoeffler, JF; Maldonado, C; María Lois, L; Rodríguez-Concepción, M; Rohmer, M1
Boronat, A; Campos, N; Gallego, F; Lois, LM; Rodríguez-Concepción, M; Sauret-Güeto, S1
Altincicek, B; Beck, E; Hintz, M; Jomaa, H; Kollas, AK; Sanderbrand, S; Wiesner, J1
Lichtenthaler, HK; Zeidler, J1
de Ruyck, J; Wouters, J1
Demmer, U; Duin, EC; Ermler, U; Hintz, M; Jomaa, H; No, JH; Oldfield, E; Rekittke, I; Röhrich, R; Troschke, K; Warkentin, E; Wiesner, J; Xu, W1
Auriola, S; Jauhiainen, M; Mönkkönen, H; Mönkkönen, J; Räikkönen, J1
Determan, MK; Hershey, DM; Lowry, L; Morrone, D; Peters, RJ; Xu, M1
Choi, ES; Chung, YR; Keasling, JD; Kim, JY; Kim, SW; Shah, AA; Wang, C; Yoon, SH1
Chang, WC; Liu, HW; Liu, P; Song, H1
Chen, X; Stephanopoulos, G; Too, HP; Zhang, C; Zhou, K; Zou, R1
Formighieri, C; Melis, A1
Baranwal, S; Krystal, G; Majumdar, AP; Pandak, WM; Patel, BB; Patel, NJ; Rodriguez-Agudo, D; Sharon, C1
Dudareva, N; Gutensohn, M; Henry, LK; Noel, JP; Thomas, ST1
Kim, SW; Wang, C; Yang, L; Zhou, J1
Bai, Z; Bi, HR; Fan, LH; Liu, CL; Tan, TW1
Darii, E; de Berardinis, V; Duquesne, K; Iacazio, G; Mariage, A; Peruch, F; Petit, JL; Rico, J1
Baysal, C; Capell, T; Christou, P; Drapal, M; Fraser, PD; Gao, L; Jin, X; Medina, V; Ni, X; Sheng, Y; Shi, L; Zhu, C1
Hemmi, H; Kitsuwa, K; Komeyama, M; Nakayama, A; Okamura, H; Saito, K; Shinada, T; Yasuno, Y1
Couillaud, J; Duquesne, K; Iacazio, G; Leydet, L1
Cao, X; Tang, F; Wang, J; Zhang, Y1

Reviews

3 review(s) available for mevalonic acid and 3,3-dimethylallyl pyrophosphate

ArticleYear
Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes.
    Current protein & peptide science, 2008, Volume: 9, Issue:2

    Topics: Acyl Coenzyme A; Animals; Bacteria; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Enzymes; Fungi; Hemiterpenes; Humans; Mevalonic Acid; Organophosphorus Compounds; Plants; Terpenes

2008
Current development in isoprenoid precursor biosynthesis and regulation.
    Current opinion in chemical biology, 2013, Volume: 17, Issue:4

    Topics: Animals; Biosynthetic Pathways; Hemiterpenes; Humans; Mevalonic Acid; Organophosphorus Compounds; Terpenes

2013
The Terpene Mini-Path, a New Promising Alternative for Terpenoids Bio-Production.
    Genes, 2021, 12-10, Volume: 12, Issue:12

    Topics: Erythritol; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Terpenes

2021

Other Studies

22 other study(ies) available for mevalonic acid and 3,3-dimethylallyl pyrophosphate

ArticleYear
Acid-catalyzed formation of isoprene from a mevalonate-derived product using a rat liver cytosolic fraction.
    The Journal of biological chemistry, 1985, Feb-10, Volume: 260, Issue:3

    Topics: Adenosine Triphosphate; Animals; Butadienes; Cytosol; Hemiterpenes; Hydrochloric Acid; Hydrogen-Ion Concentration; Kinetics; Liver; Mevalonic Acid; Organophosphorus Compounds; Pentanes; Rats

1985
In vitro biosynthesis of isoprene from mevalonate utilizing a rat liver cytosolic fraction.
    Biochemical and biophysical research communications, 1984, Sep-17, Volume: 123, Issue:2

    Topics: Adenosine Triphosphate; Animals; Breath Tests; Butadienes; Cytosol; Female; Hemiterpenes; In Vitro Techniques; Liver; Magnesium; Male; Mevalonic Acid; Organophosphorus Compounds; Pentanes; Rats; Rats, Inbred Strains; Time Factors

1984
Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate.
    The Biochemical journal, 1993, Oct-15, Volume: 295 ( Pt 2)

    Topics: Bacteria; Carbon Isotopes; Hemiterpenes; Magnetic Resonance Spectroscopy; Mevalonic Acid; Organophosphorus Compounds; Polyisoprenyl Phosphates; Terpenes

1993
Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway.
    Biochemical and biophysical research communications, 1999, Dec-20, Volume: 266, Issue:2

    Topics: Alendronate; Alkyl and Aryl Transferases; Animals; Chromatography, High Pressure Liquid; Cytosol; Geranyltranstransferase; Hemiterpenes; Kinetics; Liver; Male; Mevalonic Acid; Organophosphorus Compounds; Polyisoprenyl Phosphates; Rats; Rats, Sprague-Dawley; Sesquiterpenes

1999
Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli.
    FEBS letters, 2000, May-19, Volume: 473, Issue:3

    Topics: Arabinose; Carbon-Carbon Double Bond Isomerases; Escherichia coli; Hemiterpenes; Mevalonic Acid; Mutagenesis, Insertional; Organophosphorus Compounds; Polymerase Chain Reaction

2000
Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis.
    The Biochemical journal, 2001, Jan-01, Volume: 353, Issue:Pt 1

    Topics: Bacterial Proteins; Carbon-Carbon Double Bond Isomerases; Carboxy-Lyases; Chromosomes, Bacterial; DNA, Recombinant; Erythritol; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genes, Bacterial; Genes, Essential; Genes, Fungal; Genes, Lethal; Genetic Engineering; Hemiterpenes; Humans; Mevalonic Acid; Nucleotidyltransferases; Operon; Organophosphorus Compounds; Phenotype; Phosphorus-Oxygen Lyases; Phosphotransferases (Alcohol Group Acceptor); Phosphotransferases (Phosphate Group Acceptor); Polyisoprenyl Phosphates; Recombination, Genetic; Sugar Phosphates

2001
GcpE is involved in the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli.
    Journal of bacteriology, 2001, Volume: 183, Issue:8

    Topics: Amino Acid Sequence; Bacterial Proteins; Enzymes; Erythritol; Escherichia coli; Gene Deletion; Genetic Complementation Test; Hemiterpenes; Mevalonic Acid; Molecular Sequence Data; Organophosphorus Compounds; Sugar Phosphates

2001
Biosynthesis of 2-methyl-3-buten-2-ol emitted from needles of Pinus ponderosa via the non-mevalonate DOXP/MEP pathway of isoprenoid formation.
    Planta, 2001, Volume: 213, Issue:2

    Topics: Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Pentanols; Pinus; Pinus ponderosa; Terpenes; Xylulose

2001
Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway.
    Journal of the American Chemical Society, 2008, Dec-24, Volume: 130, Issue:51

    Topics: Amino Acid Sequence; Animals; Bacteria; Catalysis; Evolution, Molecular; Hemiterpenes; Mevalonic Acid; Models, Chemical; Molecular Conformation; Molecular Sequence Data; Organophosphorus Compounds; Oxidoreductases; Plasmodium falciparum; Sequence Homology, Amino Acid; Terpenes

2008
Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Oct-01, Volume: 877, Issue:27

    Topics: Adenosine Triphosphate; Breast Neoplasms; Cell Line, Tumor; Chromatography, Liquid; Drug Stability; Hemiterpenes; Humans; Linear Models; Mevalonic Acid; Organophosphorus Compounds; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2009
Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering.
    Applied microbiology and biotechnology, 2010, Volume: 85, Issue:6

    Topics: Diterpenes; Erythritol; Escherichia coli; Genetic Engineering; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Sugar Phosphates

2010
Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway.
    Biotechnology and bioengineering, 2010, Oct-15, Volume: 107, Issue:3

    Topics: Culture Media; Escherichia coli; Farnesol; Gene Dosage; Gene Expression; Geranyltranstransferase; Hemiterpenes; Metabolic Networks and Pathways; Mevalonic Acid; Organophosphorus Compounds; Plasmids; Polyisoprenyl Phosphates; Sesquiterpenes

2010
Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Alkyl and Aryl Transferases; Geranyltranstransferase; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds; Polycyclic Sesquiterpenes; Polyisoprenyl Phosphates; Research Design; Sesquiterpenes

2013
Carbon partitioning to the terpenoid biosynthetic pathway enables heterologous β-phellandrene production in Escherichia coli cultures.
    Archives of microbiology, 2014, Volume: 196, Issue:12

    Topics: Biosynthetic Pathways; Carbon; Cyclohexane Monoterpenes; Cyclohexenes; Erythritol; Escherichia coli; Escherichia coli Proteins; Hemiterpenes; Lavandula; Mevalonic Acid; Monoterpenes; Organophosphorus Compounds; Picea; Recombinant Proteins; Sugar Phosphates; Synechocystis; Terpenes; Transformation, Bacterial

2014
Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo.
    Oncotarget, 2015, Jun-20, Volume: 6, Issue:17

    Topics: Animals; Apoptosis; Carbon-Carbon Double Bond Isomerases; Cell Proliferation; Colorectal Neoplasms; HCT116 Cells; Hemiterpenes; Humans; Mevalonic Acid; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; Organophosphorus Compounds; Polyisoprenyl Phosphates; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; RNA, Messenger; Sesquiterpenes; Spheroids, Cellular; Terpenes; TOR Serine-Threonine Kinases; Transplantation, Heterologous; Tumor Cells, Cultured

2015
Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Aug-11, Volume: 112, Issue:32

    Topics: Arabidopsis; Arabidopsis Proteins; Archaea; Cytosol; Gene Expression Regulation, Plant; Gene Knockout Techniques; Genes, Plant; Hemiterpenes; Kinetics; Metabolic Networks and Pathways; Mevalonic Acid; Nicotiana; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Plants, Genetically Modified; Plastids; Polyisoprenyl Phosphates; Sequence Homology, Amino Acid; Sesquiterpenes; Terpenes

2015
Combinatorial engineering of hybrid mevalonate pathways in Escherichia coli for protoilludene production.
    Microbial cell factories, 2016, Jan-19, Volume: 15

    Topics: Escherichia coli; Geranyltranstransferase; Hemiterpenes; Mevalonic Acid; Organophosphorus Compounds

2016
Engineering and manipulation of a mevalonate pathway in Escherichia coli for isoprene production.
    Applied microbiology and biotechnology, 2019, Volume: 103, Issue:1

    Topics: Alkyl and Aryl Transferases; Butadienes; Carboxy-Lyases; Enterococcus faecalis; Escherichia coli; Fermentation; Gene Expression Regulation, Bacterial; Hemiterpenes; Industrial Microbiology; Metabolic Engineering; Mevalonic Acid; Microorganisms, Genetically-Modified; Organophosphorus Compounds; Populus; Recombinant Proteins

2019
Exploring natural biodiversity to expand access to microbial terpene synthesis.
    Microbial cell factories, 2019, Feb-01, Volume: 18, Issue:1

    Topics: Archaea; Bacteria; Batch Cell Culture Techniques; Biodiversity; Carotenoids; Erythritol; Escherichia coli; Hemiterpenes; Metabolic Engineering; Mevalonic Acid; Organophosphorus Compounds; Terpenes

2019
The subcellular localization of two isopentenyl diphosphate isomerases in rice suggests a role for the endoplasmic reticulum in isoprenoid biosynthesis.
    Plant cell reports, 2020, Volume: 39, Issue:1

    Topics: Carbon-Carbon Double Bond Isomerases; Carotenoids; Chlorophyll; Endoplasmic Reticulum; Gene Expression Regulation, Plant; Hemiterpenes; Mevalonic Acid; Mitochondria; Organophosphorus Compounds; Oryza; Peroxisomes; Plant Leaves; Plants, Genetically Modified; Plastids; Terpenes

2020
Total Synthesis and Structure Confirmation of
    Journal of natural products, 2021, 10-22, Volume: 84, Issue:10

    Topics: Aeropyrum; Hemiterpenes; Hydro-Lyases; Mevalonic Acid; Molecular Structure; Organophosphates; Organophosphorus Compounds; Terpenes

2021
Enhancement of linalool production in Saccharomyces cerevisiae by utilizing isopentenol utilization pathway.
    Microbial cell factories, 2022, Oct-15, Volume: 21, Issue:1

    Topics: Acyclic Monoterpenes; Carbon; Diphosphates; DNA Copy Number Variations; Geranyltranstransferase; Hemiterpenes; Metabolic Engineering; Mevalonic Acid; Monoterpenes; Organophosphorus Compounds; Pentanols; Saccharomyces cerevisiae

2022