metyrapone and nadp
metyrapone has been researched along with nadp in 93 studies
Research
Studies (93)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 71 (76.34) | 18.7374 |
| 1990's | 17 (18.28) | 18.2507 |
| 2000's | 5 (5.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Grundlin, R; Moldéus, P; Orrenius, S; Vadi, H | 1 |
| Lemm, U; Wenzel, M | 1 |
| Belvedere, G; Cantoni, L; Garattini, S; Mussini, E; Pachecka, J; Salmona, M | 1 |
| Klinger, W; Muller, D | 1 |
| Prochukhanov, RA; Rostovtseva, TI | 1 |
| Ivanetich, KM; Lucas, SA; Marsh, JA | 1 |
| Bloemendal, H; Goos, CM; Henderson, PT; Vermorken, AJ | 1 |
| Feller, DR; Fowble, JW; Miller, DD; Son, OS | 1 |
| Grudin, R; Moldèus, P; Orrenius, S; Vadi, H | 1 |
| Beckett, AH; Gorrod, JW; Temple, DJ | 1 |
| Aoyagi, K; Ishikawa, T; Nagase, S; Narita, M; Sakamoto, M; Takemura, K | 1 |
| Gebel, T; Maser, E | 1 |
| Hasunuma, K; Tamura, Y; Terano, T; Yoshida, S | 1 |
| DeGray, JA; Mason, RP; Rao, DN | 1 |
| Ruse, MJ; Waring, RH | 1 |
| Bray, TM; Chen, GM; Janzen, EG; McCay, PB | 1 |
| Chen, NQ; Holtzman, JL; Srivastava, SP | 1 |
| Blair, IA; Jajoo, HK; Klunk, LJ; Mayol, RF | 1 |
| Maser, E; Netter, KJ | 1 |
| Duverger-van Bogaert, M; Stecca, C | 1 |
| Bertetta, C; Bossart, GD; Brown, JW; Carballeira, A; Fishman, LM | 1 |
| Hamid, AB; Smith, JE | 1 |
| Kammerer, RC; Lampe, MA | 1 |
| Coleman, JB; Condie, LW; Lamb, RG | 1 |
| Athar, M; Bickers, DR; Mukhtar, H | 1 |
| Diehl, H; Schröder, U | 1 |
| Smith, AG; Stewart, FP | 1 |
| Colca, J; Comens, PG; Jakschik, B; McDaniel, ML; Turk, J; Wolf, BA | 1 |
| Berlin, T; Larsson, R; Moldéus, P; Olsson, LI; Ross, D | 1 |
| Wickramasinghe, SN | 1 |
| Inoue, T; Kishi, T; Niwaguchi, T; Suzuki, S; Yasuda, T | 1 |
| Hildebrandt, AG; Kahl, R; Ritter, J | 1 |
| Hellmer, KH; Tabarelli, S; Uehleke, H | 1 |
| Tabarelli, S; Uehleke, H | 1 |
| Franklin, MR | 1 |
| Müller, J | 1 |
| Bergheim, P; Netter, KJ; Rathgen, GH | 1 |
| Hellmer, KH; Tabarelli-Poplawski, S; Uehleke, H | 1 |
| Cooper, DY; Rosenthal, O; Schleyer, H | 1 |
| Kahl, GF; Kahl, R; Niedermeier, F; Tüttenberg, KH | 1 |
| Grundin, R; Moldéus, P; Orrenius, S; Vadi, H | 1 |
| Davis, TK; Sloane, NH | 1 |
| Illing, HP; Kunke, S; Netter, KJ | 1 |
| O'Brien, PJ; Rahimtula, AD | 1 |
| Aust, SD; Pederson, TC | 1 |
| Gromova, O; Lyakhovich, V; Mishin, V; Tsyrlov, I | 1 |
| Kolena, J | 1 |
| Dorfman, RI; Raman, PB; Sharma, DC | 1 |
| O'Donnell, VJ; Williamson, DG | 1 |
| Péron, FG; Sanzari, NP | 1 |
| Goldman, AS | 1 |
| Ertel, RJ; Ungar, F | 2 |
| Jenner, S; Kajuschke, K; Netter, KJ | 1 |
| Harding, BW; Oldham, SB; Wilson, LD | 1 |
| Biswas, S; Coupland, RE; MacDougall, JD | 1 |
| Leibman, KC | 1 |
| Brauser, B; Sies, H | 1 |
| Dünges, W; Kahl, GF | 1 |
| Hall, PF; Young, DG | 1 |
| Kahl, GF | 1 |
| Breyer, U | 1 |
| Estabrook, RW; Franklin, MR; Hildebrandt, AG; Roots, I | 1 |
| Douch, PG; Smith, JN; Turner, JC | 1 |
| Netter, KJ | 1 |
| Dal Pra, P; Melosi, P; Rossini, L | 1 |
| Fazekas, AG; Lanthier, A; Leblanc, H; Lehoux, JG; Sandor, T | 1 |
| Leblanc, H; Lehoux, JG; Sandor, T | 1 |
| Athanassopoulos, S; Hellmer, KH; Murray, RE; Reiner, O; Uehleke, H | 1 |
| Frommer, U; Orrenius, S; Staudinger, H; Ullrich, V | 1 |
| Bolt, HM; Filser, JG; Schmiedel, G | 1 |
| Hales, BF; Jain, R | 1 |
| Rivière, JL | 1 |
| Aasen, AJ; Hansen, CE; Pedersen, JI; Støren, O; Størmer, FC | 1 |
| Ruenitz, PC; Toledo, MM | 1 |
| Garattini, E; Gazzotti, G; Salmona, M | 1 |
| Hollenberg, PF; Koop, DR | 1 |
| Chen, H; Juchau, MR; Namkung, MJ | 1 |
| Brittebo, EB; Eriksson, C | 1 |
| Smith, TJ; Stoner, GD; Yang, CS | 1 |
| Hänninen, O; Kaliste-Korhonen, E; Kärenlampi, S; Laaksonen, M | 1 |
| Bend, JR; Knickle, LC | 1 |
| Myers, CR; Pratt, PF | 1 |
| Jefcoate, CR; McNamara, BC; Yamazaki, T | 1 |
| Akhtar, MH; Mahadevan, S; Russell, F | 1 |
| Maser, E | 1 |
| Iio, R; Inoue, K; Katano, N; Yamamoto, H | 1 |
| Gaikwad, NW; Madyastha, KM | 1 |
| DOMINGUEZ, OV; SAMUELS, LT | 1 |
| FERRARI, E; GHIRINGHELLI, F; PIOTTI, LE | 1 |
| Ishihara, Y; Shiba, D; Shimamoto, N | 1 |
| Lin, CH; Lin, PH | 1 |
| Bánhegyi, G; Benedetti, A; Csala, M; Fulceri, R; Gava, B; Lizák, B; Marcolongo, P; Margittai, E; Senesi, S; Sorrentino, V | 1 |
Other Studies
93 other study(ies) available for metyrapone and nadp
| Article | Year |
|---|---|
Proceedings: Isolated liver cells: a valuable tool for the study of drug metabolism.
Topics: Alprenolol; Animals; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; In Vitro Techniques; Kinetics; Liver; Metyrapone; NADP; Proadifen; Rats | 1975 |
[Hydroxylation of testosterone and 5alpha-dihydrotestosterone--isolation of 2alpha-hydroxytestosterone (author's transl)].
Topics: Animals; Cyproterone; Dihydrotestosterone; Estradiol; Hydroxylation; Hydroxytestosterones; Male; Mass Spectrometry; Metyrapone; Microsomes, Liver; NADP; Rats; Testosterone | 1976 |
Microsomal styrene mono-oxygenase and styrene epoxide hydrase activities in rats.
Topics: Animals; Brain; Carbamazepine; Epoxide Hydrolases; Female; Hydro-Lyases; Kidney; Lung; Male; Methylcholanthrene; Metyrapone; Microsomes; Microsomes, Liver; Myocardium; NAD; NADP; Organ Specificity; Oxygenases; Phenobarbital; Proadifen; Rats; Sex Factors; Spleen; Styrenes | 1976 |
Developmental aspects of xenobiotic transformation.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Ethylmorphine; Female; Glucosephosphates; Hexobarbital; Hydrogen-Ion Concentration; Metyrapone; Microsomes, Liver; NAD; NADP; Niacinamide; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Phenobarbital; Pregnancy; Rats; Semicarbazides | 1976 |
[Structuro-metabolic mechanisms for integrating several endocrine organs].
Topics: 11-Hydroxycorticosteroids; Adrenal Cortex; Adrenocorticotropic Hormone; Alkaline Phosphatase; Animals; Estrus; Female; Histocytochemistry; Hydroxysteroid Dehydrogenases; Metyrapone; NAD; NADP; Pituitary Gland, Anterior; Pregnancy; Rats | 1979 |
Enflurane and methoxyflurane. Their interaction with hepatic cytochrome P-450 in vitro.
Topics: Animals; Cytochrome P-450 Enzyme System; Enflurane; Fluorides; In Vitro Techniques; Kinetics; Liver; Male; Methoxyflurane; Methyl Ethers; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Proadifen; Rats | 1979 |
Hydroxylation of dehydroepiandrosterone in human scalp hair follicles.
Topics: Androstenediols; Autoradiography; Carbon Monoxide; Dehydroepiandrosterone; Hair; Humans; Hydroxylation; Metyrapone; Mixed Function Oxygenases; NADP; Scalp; Subcellular Fractions | 1979 |
2-Acetylaminofluorene metabolism in rat liver microsomes: formation of 9-hydroxy-2-acetylaminofluorene and effect of hepatic enzyme modifiers.
Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Carbon Monoxide; Hydroxylation; In Vitro Techniques; Liver; Male; Metyrapone; Microsomes, Liver; NADP; Rats | 1979 |
Drug metabolism in isolated rat liver cells.
Topics: Alprenolol; Animals; Biotransformation; Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Fasting; Glucose; Glucuronates; Imipramine; Lactates; Liver; Methods; Metyrapone; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Protein Binding; Rats; Rotenone; Spectrum Analysis; Temperature; Tritium | 1975 |
The differentiation of N-oxidation and N-dealkylation of N-ethyl-N-methylaniline by rabbit liver microsomes as distinct metabolic routes.
Topics: 2,2'-Dipyridyl; Acetone; Aniline Compounds; Animals; Chloromercuribenzoates; Cysteamine; Cytochrome P-450 Enzyme System; Dealkylation; Dithiothreitol; Ethylmaleimide; Kinetics; Liver; Male; Metyrapone; Microsomes, Liver; NADP; Oxidoreductases; Proadifen; Rats; Subcellular Fractions | 1975 |
Biosynthesis of methylguanidine in the hepatic microsomal fraction.
Topics: Animals; Male; Methimazole; Methylguanidine; Metyrapone; Microsomes, Liver; NADP; Rats; Rats, Wistar; Reactive Oxygen Species | 1992 |
Characterization of carbonyl reducing activity in continuous cell lines of human and rodent origin.
Topics: Alcohol Oxidoreductases; Animals; Cell Line; Cytosol; Humans; Metyrapone; Microsomes; NADP; Quercetin; Rodentia; Subcellular Fractions | 1992 |
Formation of epoxyeicosatrienoic acids from arachidonic acid by cultured rat aortic smooth muscle cell microsomes.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Bacterial Proteins; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Metyrapone; Microsomes; Mixed Function Oxygenases; Muscle, Smooth, Vascular; NADP; NADPH-Ferrihemoprotein Reductase; Pyridines; Rats; Rats, Inbred WKY | 1991 |
Reduction of paraquat and related bipyridylium compounds to free radical metabolites by rat hepatocytes.
Topics: Animals; Benzyl Viologen; Cations; Chemical and Drug Induced Liver Injury; Cobalt; Cytochrome P-450 Enzyme System; Diquat; Electron Spin Resonance Spectroscopy; Free Radicals; Liver; Male; Metyrapone; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Paraquat; Pentetic Acid; Pyridinium Compounds; Rats | 1991 |
The S-oxidation of thioamides by rat liver microsomes.
Topics: Amines; Animals; Ethionamide; Kinetics; Male; Methimazole; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Rats, Inbred Strains | 1991 |
The role of mixed function oxidase (MFO) in the metabolism of the spin trapping agent alpha-phenyl-N-tert-butyl-nitrone (PBN) in rats.
Topics: Animals; Cyclic N-Oxides; Enzyme Induction; Kidney; Liver; Lung; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitrogen Oxides; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Spin Labels | 1991 |
The effect of substrates and inhibitors of cytochrome P-450 on the NADPH inhibition of the ATP-dependent, hepatic, microsomal calcium pump.
Topics: Aminopyrine; Animals; Benzphetamine; Calcium; Calcium-Transporting ATPases; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Imidazoles; Male; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Proadifen; Rats; Rats, Inbred Strains | 1990 |
In vitro metabolism of the antianxiety drug buspirone as a predictor of its metabolism in vivo.
Topics: Animals; Buspirone; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Hydroxylation; Liver; Male; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Pyridines; Rats; Rats, Inbred Strains | 1990 |
Purification and properties of a metyrapone-reducing enzyme from mouse liver microsomes--this ketone is reduced by an aldehyde reductase.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Female; Metyrapone; Mice; Microsomes, Liver; NADP; Oxidation-Reduction | 1989 |
N-demethylation reactions in intact erythrocytes and erythrocyte supernatant.
Topics: Aniline Compounds; Animals; Biotransformation; Cyanides; Dealkylation; Erythrocytes; In Vitro Techniques; Kinetics; Male; Metyrapone; NADP; Pentetic Acid; Rats; Rats, Inbred Strains; Subcellular Fractions | 1989 |
The adrenal gland of stranded whales (Kogia breviceps and Mesoplodon europaeus): in vitro modulation of mitochondrial steroid enzyme activities.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cattle; Cells, Cultured; Cetacea; Cholesterol; Cyclic AMP; Desoxycorticosterone; Hydroxylation; Metyrapone; Mitochondria; NADP; Rats; Rats, Inbred BUF; Species Specificity; Succinates; Whales | 1987 |
Degradation of aflatoxin by Aspergillus flavus.
Topics: Aflatoxin B1; Aflatoxins; Aspergillus flavus; Cycloheximide; Cytochrome c Group; Metyrapone; NADP; Periodic Acid; Potassium Cyanide; Proadifen | 1987 |
Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro.
Topics: Acetylcysteine; Aminopyridines; Animals; Biotransformation; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Methapyrilene; Methimazole; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole | 1987 |
The influence of CCl4 biotransformation on the activation of rat liver phospholipase C in vitro.
Topics: Animals; Biotransformation; Calcium; Carbon Tetrachloride; Enzyme Activation; Liver; Male; Metyrapone; NADP; Pyridines; Rats; Rats, Inbred Strains; Type C Phospholipases | 1988 |
Cytochrome P-450 dependent metabolism of testosterone in rat skin.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Female; Metyrapone; Microsomes; NADP; Pregnancy; Proadifen; Rats; Rats, Inbred Strains; Skin; Steroid Hydroxylases; Testosterone | 1987 |
Substrate specificity of the carbon monoxide-dependent cytochrome P-450 kinetics.
Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Metyrapone; Microsomes, Liver; NADP; Substrate Specificity; Swine | 1987 |
Metabolism of the "mixed" cytochrome P-450 inducer hexachlorobenzene by rat liver microsomes.
Topics: Acetylcysteine; Aroclors; Carbon Monoxide; Chlorobenzenes; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Ellipticines; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Hexachlorobenzene; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Molecular Weight; NADP; Pentachlorophenol; Phenobarbital; Polychlorinated Dibenzodioxins; Proadifen; Safrole | 1986 |
Arachidonic acid metabolism in isolated pancreatic islets. IV. Negative ion-mass spectrometric quantitation of monooxygenase product synthesis by liver and islets.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Catechols; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase; Masoprocol; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxygenases; Pyrazoles; Rats; SRS-A | 1985 |
Prostaglandin synthase catalyzed metabolic activation of p-phenetidine and acetaminophen by microsomes isolated from rabbit and human kidney.
Topics: Acetaminophen; Aminophenols; Animals; Arachidonic Acid; Arachidonic Acids; Glutathione; Glutathione Disulfide; Humans; Indomethacin; Kidney; Kinetics; Linolenic Acids; Lipid Peroxides; Male; Metyrapone; Microsomes; Models, Chemical; NADP; Phenetidine; Proadifen; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rabbits | 1985 |
Observations on the biochemical basis of ethanol metabolism by human macrophages.
Topics: Amitrole; Carbon Monoxide; Catalase; Cell Survival; Cells, Cultured; Ethanol; Humans; Macrophages; Metyrapone; NADP; Proadifen; Pyrazoles | 1986 |
The metabolism of 1-phenyl-2-(N-methyl-N-furfurylamino)propane (furfenorex) in the rat in vivo and in vitro.
Topics: Animals; Appetite Depressants; Biotransformation; Carbon Monoxide; Chromatography, Gas; Chromatography, Thin Layer; Furans; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Spectrophotometry | 1986 |
Effect of the antioxidant (+)-cyanidanol-3 on H2O2 formation and lipid peroxidation in liver microsomes.
Topics: Animals; Benzopyrans; Catechin; Female; Guinea Pigs; Humans; Hydrogen Peroxide; In Vitro Techniques; Lipid Peroxides; Male; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Species Specificity | 1985 |
Binding of 14 C-carbon tetrachloride to microsomal proteins in vitro and formation of CHC1 3 by reduced liver microsomes.
Topics: Anaerobiosis; Animals; Carbon Isotopes; Carbon Monoxide; Carbon Tetrachloride; Chlorofluorocarbons, Methane; Chloroform; Cystamine; Cytochrome P-450 Enzyme System; Edetic Acid; Ethylmaleimide; Gallic Acid; Glutathione; In Vitro Techniques; Kinetics; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Protein Binding; Proteins; Rabbits; Spectrophotometry | 1973 |
N-hydroxylation of 4,4'-diaminodiphenylsulphone (Dapsone) by liver microsomes, and in dogs and humans.
Topics: Animals; Carbon Monoxide; Dapsone; Dogs; Erythrocytes; Female; Hemoglobins; Humans; Hydrogen-Ion Concentration; Hydroxylation; Male; Methemoglobin; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Phenobarbital; Proteins; Rabbits; Time Factors | 1973 |
Piperonyl butoxide metabolism by cytochrome P-450: factors affecting the formation and disappearance of the metabolite-cytochrome P-450 complex.
Topics: Animals; Cysteamine; Cytochrome P-450 Enzyme System; Dioxoles; Glucuronates; Hexobarbital; Kinetics; Male; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Pesticide Synergists; Piperonyl Butoxide; Protein Binding; Rats; S-Adenosylmethionine; Spectrophotometry; Uridine Diphosphate Sugars | 1972 |
Regulation of aldosterone biosynthesis.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Cations, Divalent; Cations, Monovalent; Central Nervous System; Cyclic AMP; Heparin; Humans; Hypertension, Renal; Hypophysectomy; Hypopituitarism; Metyrapone; NADP; Nephrectomy; Ouabain; Potassium; Progestins; Serotonin; Sodium | 1971 |
Interaction of drugs and steroids with human placental microsomes.
Topics: Acetanilides; Amphetamine; Anaerobiosis; Androgens; Aniline Compounds; Anisoles; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport; Female; Glucosephosphate Dehydrogenase; Humans; Kinetics; Methyltransferases; Metyrapone; Microsomes; Mixed Function Oxygenases; Myocardium; NADP; Oxidation-Reduction; Oxidoreductases; Pharmaceutical Preparations; Placenta; Pregnancy; Pregnenolone; Progesterone | 1973 |
Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Radioisotopes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Glutathione; Halothane; In Vitro Techniques; Kidney; Lung; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Proadifen; Protein Binding; Rabbits; Spectrophotometry; Sulfites | 1973 |
The heme protein P-450 in steroid hydroxylation.
Topics: Adrenal Glands; Animals; Binding Sites; Corticosterone; Cyanides; Cytochrome c Group; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Fluorides; Heme; Hemoglobins; Horses; Humans; Iron; Metyrapone; Myocardium; NADP; Pregnenolone; Protein Binding; Species Specificity; Spectrophotometry; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Steroid Hydroxylases | 1973 |
Proceedings: Evidence for oxidative metabolism of metyrapone in rat liver microsomes.
Topics: Animals; Chromatography, Thin Layer; In Vitro Techniques; Kinetics; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Rats; Spectrophotometry, Ultraviolet | 1974 |
A study of drug metabolism linked to cytochrome P-450 in isolated rat-liver cells.
Topics: Adenosine Triphosphate; Alprenolol; Animals; Antimycin A; Cell Survival; Cyanides; Cytochrome P-450 Enzyme System; Cytoplasm; Gluconeogenesis; Histocytochemistry; In Vitro Techniques; Lactates; Liver; Malate Dehydrogenase; Male; Metyrapone; Microsomes, Liver; Mitochondria, Liver; NADP; Oxygen Consumption; Pentosephosphates; Phenobarbital; Rats; Rotenone; Spectrophotometry; Starvation; Uncoupling Agents | 1974 |
Hydroxymethylation of the benzene ring. Microsomal hydroxymethylation of benzo(alpha)pyrene to 6-hydroxymethylbenzo(alpha)pyrene.
Topics: Aminoglutethimide; Animals; Benzopyrenes; Butanones; Carbon Monoxide; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Drug Stability; Female; Imidazoles; Methanol; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Temperature; Time Factors; Transferases; Tritium; Ultrasonics | 1974 |
On the spectral intermediate at 440 nm formed during mixed function substrate oxidation.
Topics: Acetanilides; Aniline Compounds; Animals; Barbiturates; Cytochrome P-450 Enzyme System; Desipramine; Imipramine; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pentobarbital; Proadifen; Protein Binding; Rats; Spectrophotometry, Ultraviolet | 1974 |
Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450.
Topics: Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Coumarins; Cyanides; Cytochrome P-450 Enzyme System; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen Consumption; Peroxides; Phenobarbital; Phenols; Phenylenediamines; Proadifen; Rabbits; Rats; Sodium Dodecyl Sulfate; Species Specificity; Superoxide Dismutase; Time Factors | 1974 |
Relationship between reduced nicotinamide adenine dinucleotide phosphate-dependent lipid peroxidation and drug hydroxylation in rat liver microsomes.
Topics: Animals; Ascorbic Acid; Benzopyrenes; Hydroxylation; In Vitro Techniques; Lipid Metabolism; Lipids; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Peroxides; Pharmaceutical Preparations; Phenobarbital; Rats | 1974 |
Phospholipids as cinchocain action site during inhibition of lipoperoxidative reactions in rat liver microsomes.
Topics: Animals; Ascorbic Acid; Binding Sites; Biotransformation; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dibucaine; Electron Transport; In Vitro Techniques; Lipid Metabolism; Male; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen Consumption; Peroxidases; Peroxides; Phosphatidylethanolamines; Phospholipids; Rats | 1974 |
Formation of androgens from 17 alpha-hydroxyprogesterone-4-14C by rat adrenal homogenates.
Topics: 17-Ketosteroids; Adrenal Glands; Androgens; Androstanes; Animals; Chromatography; Crystallization; Hexosephosphates; Hydroxyprogesterones; Male; Metyrapone; NADP; Niacinamide; Rats; Testosterone | 1969 |
Studies on aldosterone biosynthesis in vitro.
Topics: Adrenal Glands; Alcohol Oxidoreductases; Aldosterone; Animals; Cattle; Corticosterone; Ethylmaleimide; Guinea Pigs; In Vitro Techniques; Metyrapone; Mitochondria; Mixed Function Oxygenases; NAD; NADP; Naphthalenes; Pyridines; Sheep | 1966 |
Mechanism of metopirone inhibition of a soluble adrenal steroid 11-beta-hydroxylase.
Topics: Adrenal Glands; Animals; Carbon Isotopes; Cattle; In Vitro Techniques; Kinetics; Metyrapone; Mixed Function Oxygenases; NADP; Spectrophotometry | 1967 |
Influence of metopirone on substrate-supported hydroxylation of DOC by rat adrenal mitochondria.
Topics: Adrenal Glands; Animals; Citrates; Cytochromes; Desoxycorticosterone; Electron Transport; Fluorometry; In Vitro Techniques; Ketoglutaric Acids; Male; Metyrapone; Mitochondria; NADP; Nucleotides; Oxygen Consumption; Rats; Succinates | 1966 |
Experimental model of congenital adrenal cortical hyperplasia produced in utero with an inhibitor of 11-beta-steroid hydroxylase.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Animals; Corticosterone; Female; Fetal Diseases; Fetus; Glucosephosphate Dehydrogenase; Histocytochemistry; Maternal-Fetal Exchange; Metabolism, Inborn Errors; Metyrapone; Mixed Function Oxygenases; Models, Biological; NADP; Pregnancy; Pregnancy, Animal; Rats | 1967 |
20-alpha-Hydroxysteroid dehydrogenase and reductive pathways in mouse adrenal glands in vitro.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Desoxycorticosterone; Female; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Metyrapone; Mice; NADP; Pregnanediol; Pregnenolone; Progesterone | 1968 |
[On the effect of metyrapone on microsomal drug metabolism].
Topics: Acetanilides; Aminopyrine; Animals; Depression, Chemical; Glucosephosphate Dehydrogenase; Liver; Metyrapone; Mice; Microsomes; Mixed Function Oxygenases; NADP; Nitrobenzenes; Rats | 1967 |
Cytochrome P450 and steroid 11beta-hydroxylation in mitochondria from human adrenal cortex.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Antimycin A; Breast Neoplasms; Carbon Monoxide; Cushing Syndrome; Cytochromes; Electron Transport; Humans; Malates; Metyrapone; Mitochondria; Mixed Function Oxygenases; NAD; NADP; Spectrophotometry; Stereoisomerism; Stimulation, Chemical; Succinates | 1968 |
The effect of progesterone, glucose-6-phosphate dehydrogenase, adrenocorticotrophic hormone and metyrapone on adrenocortical secretion of rat adrenal glands cultured under hyperbaric oxygen.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Culture Techniques; Female; Glucosephosphate Dehydrogenase; Hyperbaric Oxygenation; Male; Metyrapone; NADP; Phosphates; Progesterone; Rats; Secretory Rate | 1969 |
Effects of metyrapone on liver microsomal drug oxidations.
Topics: Acetanilides; Aminopyrine; Animals; Depression, Chemical; Hexobarbital; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Morphine; NADP; Phenobarbital; Rats; Sleep; Stimulation, Chemical; Trichloroethylene; Tyramine | 1969 |
Interaction of mixed function oxidase with its substrates and associated redox transitions of cytochrome P-450 and pyridine nucleotides in perfused rat liver.
Topics: Animals; Cytochromes; Endoplasmic Reticulum; Fluorescence; Hexobarbital; Lactates; Liver; Male; Metyrapone; Microsomes, Liver; NAD; NADP; Oxidoreductases; Oxygen Consumption; Perfusion; Phenobarbital; Pyruvates; Rats; Spectrophotometry | 1970 |
Metabolism of metyrapone by a soluble enzyme system in rat liver.
Topics: Animals; Biotransformation; Chromatography, Thin Layer; Liver; Male; Metyrapone; Microsomes, Liver; NADP; Oxidoreductases; Rats; Spectrophotometry; Ultraviolet Rays | 1970 |
Steroid hydroxylation in bovine adrenocortical mitochondria. Competition between side-chain cleavage of cholesterol and 11 beta hydroxylation.
Topics: Adrenal Glands; Animals; Calcium; Carbon Isotopes; Cattle; Cell Fractionation; Cholesterol; Corticosterone; Cytochromes; Depression, Chemical; Desoxycorticosterone; Feedback; In Vitro Techniques; Kinetics; Metyrapone; Mitochondria; Mixed Function Oxygenases; NADP; Pregnenolone | 1971 |
[Reductive degradation of metyrapone in rat liver].
Topics: Animals; Metyrapone; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Rats | 1970 |
Metabolism of the phenothiazine drug perazine by liver and lung microsomes from various species.
Topics: Animals; Cats; Chromatography, Thin Layer; Cytochromes; Dealkylation; Guinea Pigs; Hydroxylation; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; NADP; Oxides; Phenothiazines; Proadifen; Rabbits; Rats; Species Specificity; Spectrophotometry; Sulfoxides; Swine; Tranquilizing Agents | 1971 |
The inhibitory effect of metyrapone on cytochrome P-450-catalyzed mixed-function oxidation reactions as compared to the effect of carbon monoxide.
Topics: Carbon Monoxide; Cytochromes; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction | 1971 |
NADPH-dependent cleavage of carbamates.
Topics: Administration, Oral; Animals; Bees; Carbamates; Coleoptera; Diptera; Glucosephosphate Dehydrogenase; Glucosephosphates; Houseflies; Hydrolysis; In Vitro Techniques; Injections, Intraperitoneal; Insecticides; Metyrapone; Mice; Microsomes, Liver; NADP; Oxidation-Reduction; Piperonyl Butoxide; Proadifen; Tritium | 1971 |
[Fundamentals of drug metabolism].
Topics: Animals; Anisoles; Biotransformation; Electron Transport Complex IV; Formaldehyde; Humans; Kinetics; Liver; Metyrapone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Models, Biological; NADP; Nitro Compounds; Nitrophenols; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pharmaceutical Preparations; Rats | 1972 |
Ethanol and metyrapone effect on the redox potential, its compartimentalization, and its relation to the high energy phosphates of the rat liver in vivo.
Topics: Animals; Ethanol; Hydroxybutyrate Dehydrogenase; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Ligases; Liver; Malate Dehydrogenase; Male; Metyrapone; NAD; NADP; Oxidation-Reduction; Oxidative Phosphorylation; Oxidoreductases; Pyruvates; Rats | 1972 |
Studies on the biosynthesis of 18-oxygenated steroids from exogenous corticosterone by domestic duck (Anas platyrhynchos) adrenal gland mitochondria.
Topics: Adrenal Glands; Aldosterone; Aminopterin; Animals; Calcium; Carbon Isotopes; Carbon Monoxide; Chloromercuribenzoates; Corticosterone; Cytochrome P-450 Enzyme System; Ducks; Enzyme Activation; Hydroxycorticosteroids; Kinetics; Magnesium; Male; Metyrapone; Mitochondria; NADP; Potassium; Sodium; Structure-Activity Relationship; Tritium | 1972 |
[Adrenal gland 21-hydroxylase from the domestic duck (Anas platyrhynchos)].
Topics: Adrenal Glands; Animals; Carbon Isotopes; Carbon Monoxide; Chloromercuribenzoates; Cytochrome c Group; Cytochrome P-450 Enzyme System; Ducks; Hydroxyprogesterones; Kinetics; Metyrapone; Microsomes; Mixed Function Oxygenases; NADP; Progesterone; Species Specificity; Spectrophotometry; Structure-Activity Relationship; Temperature | 1972 |
[Formation of chloroform from carbon tetrachloride in liver microsomes, lipid peroxidation and destruction of cytochrome P-450].
Topics: Alcohols; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Desipramine; Disulfiram; Flavonoids; Linoleic Acids; Lipid Metabolism; Male; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Oxygenases; Piperonyl Butoxide; Rabbits; Rats; Ultraviolet Rays | 1972 |
The monooxygenation of N-heptane by rat liver microsomes.
Topics: Aerobiosis; Alcohols; Alkanes; Animals; Carbon Monoxide; Chromatography, Gas; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Isomerism; Kinetics; Mass Spectrometry; Metyrapone; Microsomes, Liver; Myocardium; NADP; Oxidation-Reduction; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Swine; Vibration | 1972 |
Rat liver microsomal transformation of ethene to oxirane in vitro.
Topics: Alkylation; Animals; Biotransformation; Cobalt; Ditiocarb; Ethylene Oxide; Ethylenes; Male; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred Strains | 1983 |
Characteristics of the activation of cyclophosphamide to a mutagen by rat liver.
Topics: Animals; Biotransformation; Cyclophosphamide; Cytochrome P-450 Enzyme System; Flavonoids; In Vitro Techniques; Liver; Male; Metyrapone; Mutagens; NADP; Phenobarbital; Proadifen; Rats; Salmonella typhimurium | 1980 |
7-Ethoxycoumarin dealkylase and cytochrome P-450 from grey partridge (Perdix perdix) hepatic and duodenal microsomes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Birds; Cytochrome P-450 Enzyme System; Duodenum; Kinetics; Metyrapone; Microsomes; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxygenases | 1980 |
Formation of (4R)- and (4S)-4-hydroxyochratoxin A and 10-hydroxyochratoxin A from Ochratoxin A by rabbit liver microsomes.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Hydroxylation; Magnetic Resonance Spectroscopy; Male; Metyrapone; Microsomes, Liver; NADP; Ochratoxins; Phenobarbital; Rabbits | 1983 |
Chemical and biochemical characteristics of O-demethylation of chlorotrianisene in the rat.
Topics: Animals; Chemical Phenomena; Chemistry; Chlorotrianisene; Dealkylation; Female; Male; Metyrapone; Microsomes, Liver; NADP; Proadifen; Rats; Rats, Inbred Strains | 1981 |
Nuclear metabolism. I. Determination of styrene monooxygenase activity in rat liver nuclei.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; In Vitro Techniques; Liver; Male; Metyrapone; Microsomes, Liver; NAD; NADP; Nuclear Envelope; Phenobarbital; Rats; Styrenes | 1980 |
Liver microsomal metabolism of N-methylcarbazole: a probe for induction, inhibition, and species differences.
Topics: Animals; Benzoflavones; Carbazoles; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Phenobarbital; Proadifen; Rabbits; Rats; Species Specificity | 1980 |
Biotransformation of all-trans-retinol and all-trans-retinal to all-trans-retinoic acid in rat conceptal homogenates.
Topics: Acyclic Monoterpenes; Animals; Biotransformation; Embryo, Mammalian; Embryonic and Fetal Development; Enzyme Inhibitors; Gestational Age; In Vitro Techniques; Metyrapone; Monoterpenes; NAD; NADP; Rats; Rats, Sprague-Dawley; Rats, Wistar; Retinaldehyde; Terpenes; Tretinoin; Vitamin A | 1995 |
Effects of the herbicide chlorthiamid on the olfactory mucosa.
Topics: Animals; Binding Sites; Biotransformation; Cytochrome P-450 Enzyme System; Ditiocarb; Female; In Vitro Techniques; Injections, Intraperitoneal; Metyrapone; Mice; Mice, Inbred C57BL; Microsomes, Liver; NADP; Nitriles; Olfactory Mucosa; Rats; Rats, Sprague-Dawley; Staining and Labeling; Thioamides; Tissue Fixation | 1995 |
Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
Topics: Aldehydes; Arachidonic Acids; Carbon Monoxide; Carcinogens; Coumarins; Cytochrome P-450 Enzyme System; Humans; Hydrogen Peroxide; Lipoxygenase; Lung; Metyrapone; Microsomes; NADP; Nitrosamines; Oxidation-Reduction; Superoxide Dismutase; Temperature | 1995 |
P450 enzyme CYP2B catalyzes the detoxification of diisopropyl fluorophosphate.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cell Line; Clotrimazole; Cricetinae; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Inactivation, Metabolic; Isoflurophate; Isoquinolines; Male; Metyrapone; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Rats; Rats, Wistar; Steroid Hydroxylases | 1995 |
Bioactivation of arachidonic acid by the cytochrome P450 monooxygenases of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for formation of epoxyeicosatrienoic acids.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Guinea Pigs; Lung; Male; Metyrapone; Microsomes; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Triazoles | 1994 |
Enzymatic reduction of chromium(VI) by human hepatic microsomes.
Topics: Adult; Carbon Monoxide; Carcinogens, Environmental; Chromium; Female; Glucosephosphate Dehydrogenase; Humans; Male; Metyrapone; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Oxygen; Thallium | 1993 |
Competition for electron transfer between cytochromes P450scc and P45011 beta in rat adrenal mitochondria.
Topics: Adrenal Cortex; Adrenodoxin; Aminoglutethimide; Animals; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cosyntropin; Desoxycorticosterone; Electron Transport; Female; Ferredoxin-NADP Reductase; Isocitrates; Isoenzymes; Metyrapone; Mitochondria; NADP; Oxidation-Reduction; Pregnenolone; Rats; Rats, Sprague-Dawley; Steroid 11-beta-Hydroxylase; Succinates; Succinic Acid | 1993 |
Cleavage of 3-phenoxybenzoic acid by chicken microsomal preparations.
Topics: 2,2'-Dipyridyl; Animals; Benzoates; Carbon Monoxide; Chickens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cross-Linking Reagents; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Kidney; Metyrapone; Microsomes; NADP; Oxygen; Phenanthrolines; Piperonyl Butoxide | 1993 |
The purification and properties of a novel carbonyl reducing enzyme from mouse liver microsomes.
Topics: Alcohol Oxidoreductases; Animals; Cytosol; Female; Guinea Pigs; Humans; In Vitro Techniques; Male; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Rats; Rats, Wistar; Species Specificity; Substrate Specificity | 1993 |
7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures.
Topics: Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Glucosides; Iridoids; Ketoconazole; Magnoliopsida; Metyrapone; Miconazole; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Oxygen Consumption; Pyrans | 2001 |
Biosynthesis of beta-substituted furan skeleton in the lower furanoterpenoids: a model study.
Topics: Animals; Cytochrome P-450 Enzyme System; Furans; Gas Chromatography-Mass Spectrometry; Ketones; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Metyrapone; Microsomes, Liver; Models, Chemical; NADP; Oxygen; Rats; Rats, Wistar | 2002 |
MECHANISM OF INHIBITION OF ADRENAL STEROID 11BETA-HYDROXYLASE BY METHOPYRAPONE (METOPIRONE).
Topics: Adrenal Cortex Hormones; Adrenal Glands; Carbon Isotopes; Corticosterone; Desoxycorticosterone; Enzyme Inhibitors; Ketones; Metabolism; Metyrapone; Mixed Function Oxygenases; NADP; Pharmacology; Progesterone; Rats; Research; Steroid 11-beta-Hydroxylase | 1963 |
[THE ADRENAL HISTO-ENZYMATIC PICTURE DURING PHARMACOLOGICAL BLOCKING OF 11-BETA-HYDROXYLATION IN RATS].
Topics: Adrenal Cortex Hormones; Adrenal Glands; Dihydrolipoamide Dehydrogenase; Glucosephosphate Dehydrogenase; Hydroxylation; Ketones; Metabolism; Metyrapone; Mineralocorticoid Receptor Antagonists; NAD; NADP; Pharmacology; Rats; Research | 1963 |
IN VITRO EFFECT OF 2-METHYL-1,2-BIS(3-PYRIDYL)-1-PROPANONE (SU-4885) AND NADPH IN THE MOUSE ADRENAL.
Topics: Adrenal Glands; Animals; Corticosterone; Desoxycorticosterone; In Vitro Techniques; Metabolism; Metyrapone; Mice; Mineralocorticoid Receptor Antagonists; NADP; Oxidation-Reduction; Pharmacology; Progesterone; Research | 1964 |
Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition.
Topics: Animals; Antioxidants; Benzoquinones; Catecholamines; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glutathione Disulfide; Hepatocytes; Imidazolines; Iron Chelating Agents; Ketoconazole; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Metyrapone; Molecular Structure; NADP; Naphthoquinones; Oxidative Stress; Proadifen; Rats; Rats, Wistar; Superoxides; Thiobarbituric Acid Reactive Substances | 2006 |
Induction of ROS formation, poly(ADP-ribose) polymerase-1 activation, and cell death by PCB126 and PCB153 in human T47D and MDA-MB-231 breast cancer cells.
Topics: Benzoflavones; Breast Neoplasms; Catalase; Cell Line, Tumor; Cell Survival; Chelating Agents; Cytochrome P-450 Enzyme Inhibitors; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Fluoresceins; Humans; Metyrapone; Molecular Structure; NAD; NADP; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Biphenyls; Reactive Oxygen Species; Tamoxifen | 2006 |
Metyrapone prevents cortisone-induced preadipocyte differentiation by depleting luminal NADPH of the endoplasmic reticulum.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Cortisone; Endoplasmic Reticulum; Enzyme Inhibitors; Fibroblasts; Humans; Male; Mesenchymal Stem Cells; Metyrapone; Mice; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2008 |