metyrapone and mifepristone

metyrapone has been researched along with mifepristone in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.39)18.7374
1990's9 (15.25)18.2507
2000's26 (44.07)29.6817
2010's21 (35.59)24.3611
2020's1 (1.69)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Sikes, CR; Stokes, PE2
Crapo, L; Miller, JW1
Farsky, SP; Garcia-Leme, J; Sannomiya, P1
Khalil, MW; Killinger, DW; Strutt, B; Vachon, D1
Ashwell, JD; Papadopoulos, V; Vacchio, MS1
Heikinheimo, O; Spitz, IM; Wade, CE1
Curi, R; Newsholme, EA; Parry-Billings, M; Serrano, MA; Williams, JF1
Ovadia, H; Tarcic, N; Weidenfeld, J; Weiss, DW1
Arvat, E; Boscaro, M; Broglio, F; Deghenghi, R; Ghigo, E; Giordano, R; Maccagno, B; Ramunni, J1
Joëls, M; Korf, J; Krugers, HJ; Maslam, S; Van Vuuren, SM1
Boyd, RL; Cole, TJ; Godfrey, DI; Purton, JF1
Bernier, NJ; Peter, RE1
Calvo, N; Volosin, M1
Handschin, C; Hoffmann, K; Meyer, UA; Podvinec, M; Stöckli, J1
Couch, DB; Kozlowski, RS; Sawant, SG1
Baker, D; Giovannoni, G; Pryce, G1
Armario, A; Dal-Zotto, S; Martí, O1
Ahnblad, P; Georén, S; Stierna, P; Stjärne, P; Wikström, AC1
Bonneau, RH; Nair, A1
Croft, AP; Jacquot, C; Little, HJ; O'Callaghan, MJ1
Bian, Z; Canlon, B; Hansson, AC; Johansson, P; Meltser, I; Stierna, P; Tahera, Y1
Hui, X; Wang, MW; Zhou, CH1
Franklin, SO; Jimenez, R1
Young, AH1
Craft, TK; DeVries, AC1
Canlon, B; Johansson, P; Meltser, I; Tahera, Y1
Canlon, B; Hansson, AC; Johansson, P; Meltser, I; Tahera, Y1
Andrew, R; Homer, NZ; Karpe, F; Stimson, RH; Tan, GD; Wake, DJ; Walker, BR1
Dang, CN; Trainer, P1
Hajhashemi, V; Mesripour, A; Rabbani, M1
Ghitza, UE; Li, YQ; Lu, L; Wang, XY; Zhao, M1
Budziszewska, B; Chocyk, A; Grzegorzewska, M; Hess, G; Maćkowiak, M; Wedzony, K1
Li, L; Messina, JL; Thompson, LH; Zhao, L1
Coleman, VH; Kling, MA; Schulkin, J1
Conboy, L; Sandi, C1
Hu, G; Liu, R; Shen, Z; Zhang, S; Zhang, X1
Bagaeva, T; Bobryshev, P; Filaretova, L1
Castro, FM; de Mello, SB; Guzzo, ML; Saad Rached, IC1
Alexandraki, KI; Grossman, AB1
Danielewicz, J; Hess, G; Spyrka, J1
Esbaugh, AJ; Gilmour, KM; McDonald, MD; Rodela, TM; Walsh, PJ1
Biller, BM; Tritos, NA1
Barahona Constanzo, MJ; del Pozo Picó, C1
Besedovsky, L; Born, J; Lange, T1
Almeida da Silva, CL; Gaspar-Elsas, MI; Lopes, RS; Luz, RA; Masid-de-Brito, D; Queto, T; Vieira, BM; Xavier-Elsas, P1
Bitencourt, RM; Pamplona, FA; Takahashi, RN1
Besedovsky, L; Born, J; Dimitrov, S; Groch, S; Lange, T; Linz, B1
Andrew, R; Bastin, ME; Gray, CD; Iredale, JP; Macfarlane, DP; Marshall, I; Preston, T; Raubenheimer, PJ; Walker, BR1
Gehlert, DR; Shaw, J1
Almada, RC; Brandão, ML; Fogaça, MV; Reis, FM1
Ebada, ME; Kendall, DA; Pardon, MC1
Ayala, A; Biller, BMK; Bonert, V; Broder, MS; Carmichael, JD; Cherepanov, D; Eagan, M; Geer, EB; Gordon, MB; Hannoush, Z; Katznelson, L; Lalazar, Y; Lee, J; Manuylova, E; Neary, MP; Pulaski-Liebert, KJ; Said, Q; Shafiq, I; Surampudi, V; Swerdloff, RS1
Costa, G; Morelli, M; Paci, E; Serra, M; Simola, N1
Berlinsky, DL; Breton, TS; Kenter, LW; Miller, KA1
Athimulam, S; Bancos, I; Delivanis, DA1
Castinetti, F1

Reviews

12 review(s) available for metyrapone and mifepristone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The hypothalamic-pituitary-adrenocortical axis in major depression.
    Endocrinology and metabolism clinics of North America, 1988, Volume: 17, Issue:1

    Topics: Adrenocorticotropic Hormone; Body Fluids; Corticotropin-Releasing Hormone; Depressive Disorder; Estrenes; Humans; Hypothalamo-Hypophyseal System; Metyrapone; Mifepristone; Physostigmine; Pituitary-Adrenal Function Tests; Pituitary-Adrenal System; Vasopressins

1988
The hypothalamic-pituitary-adrenocortical axis in major depression.
    Neurologic clinics, 1988, Volume: 6, Issue:1

    Topics: Adrenocorticotropic Hormone; Brain; Corticotropin-Releasing Hormone; Depressive Disorder; Estrenes; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Metyrapone; Mifepristone; Pituitary-Adrenal Function Tests; Pituitary-Adrenal System; Receptors, Glucocorticoid; Saliva

1988
The medical treatment of Cushing's syndrome.
    Endocrine reviews, 1993, Volume: 14, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aminoglutethimide; Animals; Bromocriptine; Cushing Syndrome; Cyproheptadine; Dogs; Horses; Humans; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Octreotide; Palliative Care; Pituitary Gland; Radiography; Valproic Acid

1993
Stress-free T-cell development: glucocorticoids are not obligatory.
    Immunology today, 2000, Volume: 21, Issue:12

    Topics: Aminoglutethimide; Animals; Cell Differentiation; Clonal Deletion; DNA, Antisense; Glucocorticoids; Hematopoiesis; Hormone Antagonists; Humans; Immunologic Deficiency Syndromes; Lymphocyte Activation; Metyrapone; Mice; Mice, Knockout; Mice, Transgenic; Mifepristone; Models, Biological; Receptors, Glucocorticoid; Stress, Physiological; T-Lymphocyte Subsets; Thymus Gland

2000
Glucocorticoid receptor and treatment of psychotic major depression.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:11

    Topics: Animals; Brain; Dehydroepiandrosterone; Depressive Disorder, Major; Humans; Metyrapone; Mifepristone; Psychotic Disorders; Pyrimidines; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucocorticoid

2005
Antiglucocoticoid treatments for depression.
    The Australian and New Zealand journal of psychiatry, 2006, Volume: 40, Issue:5

    Topics: Adrenocortical Hyperfunction; Dehydroepiandrosterone; Depressive Disorder, Major; Enzyme Inhibitors; Hormone Antagonists; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Metyrapone; Mifepristone; Pituitary-Adrenal System

2006
Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus?
    Depression and anxiety, 2009, Volume: 26, Issue:7

    Topics: Adrenal Glands; Aminoglutethimide; Anti-Inflammatory Agents; Corticotropin-Releasing Hormone; Depressive Disorder, Major; Double-Blind Method; Glucocorticoids; Humans; Hydrocortisone; Hypothalamus; Ketoconazole; Metyrapone; Mifepristone; Severity of Illness Index

2009
Medical therapy of Cushing's disease: where are we now?
    Frontiers of hormone research, 2010, Volume: 38

    Topics: Dopamine Agonists; Humans; Hydrocortisone; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Pituitary ACTH Hypersecretion; Somatostatin

2010
Advances in medical therapies for Cushing's syndrome.
    Discovery medicine, 2012, Volume: 13, Issue:69

    Topics: Animals; Bexarotene; Cushing Syndrome; Etomidate; Humans; Ketoconazole; Lapatinib; Metyrapone; Mifepristone; Mitotane; Quinazolines; Somatostatin; Tetrahydronaphthalenes

2012
New prospects for drug treatment in Cushing disease.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:10

    Topics: Adenoma; Adrenocorticotropic Hormone; Animals; Cabergoline; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Drug Evaluation, Preclinical; Ergolines; Etomidate; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Metyrapone; Mice; Mifepristone; Mitotane; Multicenter Studies as Topic; Pituitary ACTH Hypersecretion; Pituitary Neoplasms; PPAR gamma; Pyridines; Rats; Somatostatin; Therapies, Investigational; Tretinoin

2012
How best to monitor the specific side effects of medical treatments of Cushing's disease.
    Best practice & research. Clinical endocrinology & metabolism, 2022, Volume: 36, Issue:6

    Topics: Humans; Metyrapone; Mifepristone; Pituitary ACTH Hypersecretion; Pituitary Gland; Retrospective Studies

2022

Trials

5 trial(s) available for metyrapone and mifepristone

ArticleYear
Corticotropin-releasing effect of hexarelin, a peptidyl GH secretagogue, in normal subjects pretreated with metyrapone or RU-486, a glucocorticoid receptor antagonist, and in patients with Addison's disease.
    Neuroendocrinology, 1999, Volume: 70, Issue:3

    Topics: Addison Disease; Adrenocorticotropic Hormone; Adult; Aged; Female; Growth Substances; Hormone Antagonists; Human Growth Hormone; Humans; Hydrocortisone; Male; Metyrapone; Middle Aged; Mifepristone; Oligopeptides; Receptors, Glucocorticoid

1999
Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:5

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adult; Aged; Cortisone; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Fenofibrate; Gas Chromatography-Mass Spectrometry; Hormone Antagonists; Humans; Hydrocortisone; Hypolipidemic Agents; Insulin Resistance; Kinetics; Liver; Male; Metyrapone; Microdialysis; Middle Aged; Mifepristone; Obesity; PPAR alpha; PPAR gamma; Rosiglitazone; Subcutaneous Fat; Thiazolidinediones

2007
Endogenous glucocorticoid receptor signaling drives rhythmic changes in human T-cell subset numbers and the expression of the chemokine receptor CXCR4.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014, Volume: 28, Issue:1

    Topics: Adult; Chemokine CXCL12; Circadian Rhythm; Female; Flow Cytometry; Humans; Hydrocortisone; Male; Metyrapone; Mifepristone; Receptors, CXCR4; Receptors, Glucocorticoid; Signal Transduction; T-Lymphocyte Subsets; Young Adult

2014
Cortisol increases CXCR4 expression but does not affect CD62L and CCR7 levels on specific T cell subsets in humans.
    American journal of physiology. Endocrinology and metabolism, 2014, Jun-01, Volume: 306, Issue:11

    Topics: Adult; Anti-Inflammatory Agents; Antimetabolites; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cross-Over Studies; Double-Blind Method; Hormone Antagonists; Humans; Hydrocortisone; L-Selectin; Male; Metyrapone; Mifepristone; Receptors, CCR7; Receptors, CXCR4; Receptors, Glucocorticoid; T-Lymphocyte Subsets; Young Adult

2014
Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with Type 2 diabetes with and without fatty liver.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Oct-01, Volume: 307, Issue:7

    Topics: Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Energy Metabolism; Enzyme Inhibitors; Fatty Acids, Nonesterified; Glycerol; Hormone Antagonists; Humans; Hydrocortisone; Indicator Dilution Techniques; Insulin; Liver; Magnetic Resonance Spectroscopy; Male; Metyrapone; Middle Aged; Mifepristone; Non-alcoholic Fatty Liver Disease; Receptors, Glucocorticoid; Scotland; Steroid 11-beta-Hydroxylase; Time Factors; Treatment Outcome

2014

Other Studies

42 other study(ies) available for metyrapone and mifepristone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Secreted glucocorticoids regulate leukocyte-endothelial interactions in inflammation. A direct vital microscopic study.
    Journal of leukocyte biology, 1995, Volume: 57, Issue:3

    Topics: Adrenalectomy; Animals; CD18 Antigens; Cell Adhesion; Cycloheximide; Dactinomycin; Endothelium, Vascular; Glucocorticoids; Immunologic Techniques; Inflammation; Male; Metyrapone; Microcirculation; Mifepristone; Rats; Rats, Wistar; Regional Blood Flow

1995
Effect of dexamethasone and cytochrome P450 inhibitors on the formation of 7 alpha-hydroxydehydroepiandrosterone by human adipose stromal cells.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 48, Issue:5-6

    Topics: Adipose Tissue; Aminoglutethimide; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Dexamethasone; Humans; Ketoconazole; Metyrapone; Mifepristone; Stromal Cells

1994
Steroid production in the thymus: implications for thymocyte selection.
    The Journal of experimental medicine, 1994, Jun-01, Volume: 179, Issue:6

    Topics: Aging; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Epithelial Cells; Epithelium; Fetus; Lymphocyte Depletion; Metyrapone; Mice; Mice, Inbred BALB C; Mifepristone; Organ Culture Techniques; Pregnenolone; Receptors, Antigen, T-Cell; Receptors, Glucocorticoid; Signal Transduction; T-Lymphocytes; Thymus Gland

1994
The divergent effect of RU 486 on adrenal function in the dog is related to differences in its pharmacokinetics.
    Acta endocrinologica, 1993, Volume: 128, Issue:5

    Topics: Administration, Oral; Adrenal Cortex; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Blood Proteins; Body Weight; Dogs; Female; Hydrocortisone; Hypoglycemia; Hypothalamo-Hypophyseal System; Insulin; Metyrapone; Mifepristone; Pituitary-Adrenal System; Time Factors

1993
Effects of glucocorticoids on lymphocyte metabolism.
    The American journal of physiology, 1993, Volume: 264, Issue:1 Pt 1

    Topics: Animals; Cells, Cultured; Circadian Rhythm; Decarboxylation; Dexamethasone; Glucose; Glutamine; Lymphocytes; Male; Metyrapone; Mifepristone; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar

1993
Restraint stress-induced thymic involution and cell apoptosis are dependent on endogenous glucocorticoids.
    Journal of neuroimmunology, 1998, Volume: 82, Issue:1

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Apoptosis; CD4-CD8 Ratio; Cell Count; Corticosterone; DNA Fragmentation; Hormone Antagonists; Immunophenotyping; Male; Metyrapone; Mice; Mice, Inbred BALB C; Mifepristone; Neuroimmunomodulation; Organ Size; Restraint, Physical; Stress, Physiological; Thymus Gland

1998
Postischemic steroid modulation: effects on hippocampal neuronal integrity and synaptic plasticity.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1999, Volume: 19, Issue:10

    Topics: Action Potentials; Animals; Brain Ischemia; Corticosterone; Dexamethasone; Electrophysiology; Epilepsy; Excitatory Postsynaptic Potentials; Glucocorticoids; Hippocampus; Hormone Antagonists; Hypoxia, Brain; Male; Metyrapone; Microtubule-Associated Proteins; Mifepristone; Neuronal Plasticity; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Wistar

1999
Appetite-suppressing effects of urotensin I and corticotropin-releasing hormone in goldfish (Carassius auratus).
    Neuroendocrinology, 2001, Volume: 73, Issue:4

    Topics: Animals; Appetite Depressants; Corticotropin-Releasing Hormone; Drug Implants; Eating; Goldfish; Hormone Antagonists; Hydrocortisone; Hypothalamus; Immunoblotting; Indicators and Reagents; Injections, Intraperitoneal; Injections, Intraventricular; Metyrapone; Mifepristone; Peptide Fragments; RNA, Messenger; Urotensins

2001
Glucocorticoid and mineralocorticoid receptors are involved in the facilitation of anxiety-like response induced by restraint.
    Neuroendocrinology, 2001, Volume: 73, Issue:4

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Anxiety; Corticosterone; Dexamethasone; Injections, Intraventricular; Male; Metyrapone; Mifepristone; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Restraint, Physical; Spironolactone; Stress, Psychological

2001
Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:9

    Topics: Animals; Avian Proteins; beta-Naphthoflavone; Cell Line; Chickens; Clotrimazole; Colforsin; Constitutive Androstane Receptor; Cyclic AMP; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Glutethimide; Growth Inhibitors; Hormone Antagonists; Humans; Metyrapone; Mifepristone; Okadaic Acid; Pregnane X Receptor; Pregnenolone Carbonitrile; Protein Binding; Pyridines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Signal Transduction; Trans-Activators; Transcription Factors

2001
The role of adrenal corticosteroids in induction of micronuclei by morphine.
    Mutation research, 2001, Nov-15, Volume: 498, Issue:1-2

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Animals; Blood Proteins; Cell Nucleus; Cells, Cultured; Codeine; Corticosterone; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Metyrapone; Mice; Mice, Inbred C57BL; Micronucleus Tests; Mifepristone; Morphine; Spleen

2001
Mifepristone or inhibition of 11beta-hydroxylase activity potentiates the sedating effects of the cannabinoid receptor-1 agonist Delta(9)-tetrahydrocannabinol in mice.
    Neuroscience letters, 2003, May-01, Volume: 341, Issue:2

    Topics: Analgesics, Non-Narcotic; Animals; Body Temperature Regulation; Conscious Sedation; Dronabinol; Drug Synergism; Enzyme Inhibitors; Hormone Antagonists; Male; Metyrapone; Mice; Mifepristone; Receptors, Cannabinoid; Receptors, Drug; Time Factors

2003
Glucocorticoids are involved in the long-term effects of a single immobilization stress on the hypothalamic-pituitary-adrenal axis.
    Psychoneuroendocrinology, 2003, Volume: 28, Issue:8

    Topics: Adaptation, Physiological; Adrenal Glands; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Corticosterone; Hormone Antagonists; Hypothalamo-Hypophyseal System; Immobilization; Male; Metyrapone; Mifepristone; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Stress, Psychological

2003
Significance of endogenous glucocorticoid sensitivity for airway eosinophilia in a murine model of allergy.
    Acta oto-laryngologica, 2005, Volume: 125, Issue:4

    Topics: Administration, Intranasal; Airway Resistance; Animals; Asthma; Bone Marrow; Bronchi; Disease Models, Animal; Enzyme Inhibitors; Eosinophilia; Glucocorticoids; Hormone Antagonists; Leukocyte Count; Lung; Metyrapone; Mice; Mice, Inbred BALB C; Mifepristone; Ovalbumin; Receptors, Glucocorticoid; Respiratory Hypersensitivity; Respiratory Mucosa; Stress, Physiological

2005
Stress-induced elevation of glucocorticoids increases microglia proliferation through NMDA receptor activation.
    Journal of neuroimmunology, 2006, Volume: 171, Issue:1-2

    Topics: Animals; Antigens, Differentiation; Brain; Cell Count; Cell Proliferation; Corticosterone; Dizocilpine Maleate; Drinking; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flow Cytometry; Glucocorticoids; Hormone Antagonists; Immunohistochemistry; Male; Metyrapone; Mice; Mice, Inbred C57BL; Microglia; Mifepristone; Models, Biological; Proliferating Cell Nuclear Antigen; Radioimmunoassay; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Stress, Physiological; Time Factors

2006
The hypothalamopituitary-adrenal axis and alcohol preference.
    Brain research bulletin, 2005, Dec-30, Volume: 68, Issue:3

    Topics: Adrenocorticotropic Hormone; Alcohol Drinking; Animals; Animals, Newborn; Behavior, Animal; Central Nervous System Depressants; Conditioning, Operant; Corticosterone; Corticotropin-Releasing Hormone; Drug Administration Schedule; Enzyme Inhibitors; Ethanol; Hormone Antagonists; Hypothalamo-Hypophyseal System; Metyrapone; Mice; Mifepristone; Pituitary-Adrenal System; Time Factors

2005
NF-kappaB mediated glucocorticoid response in the inner ear after acoustic trauma.
    Journal of neuroscience research, 2006, May-01, Volume: 83, Issue:6

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Auditory Threshold; Blotting, Northern; Disease Models, Animal; Drug Interactions; Ear, Inner; Enzyme Inhibitors; Glucocorticoids; Hearing Loss, Noise-Induced; Immunohistochemistry; In Situ Hybridization; Male; Metyrapone; Mice; Mice, Inbred CBA; Mifepristone; Neurons; NF-kappa B; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spiral Ganglion; Time Factors

2006
Increases in preproenkephalin mRNA levels in the Syrian hamster: the influence of glucocorticoids is dependent on age and tissue.
    Brain research, 2006, May-01, Volume: 1086, Issue:1

    Topics: Adrenal Glands; Age Factors; Animals; Animals, Newborn; Corpus Striatum; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; Enzyme Inhibitors; Female; Gene Expression Regulation, Developmental; Glucocorticoids; Hormone Antagonists; Hypophysectomy; Male; Metyrapone; Mifepristone; Phenylethanolamine N-Methyltransferase; Pregnancy; Protein Precursors; RNA, Messenger

2006
Role of IL-1 in poststroke depressive-like behavior in mice.
    Biological psychiatry, 2006, Oct-15, Volume: 60, Issue:8

    Topics: Animals; Antimetabolites; Depressive Disorder; Drinking Behavior; Glucocorticoids; Hormone Antagonists; Infarction, Middle Cerebral Artery; Injections, Intraventricular; Interleukin-1; Male; Metyrapone; Mice; Mice, Inbred C57BL; Mifepristone; Receptors, Glucocorticoid; Receptors, Interleukin-1; Stroke; Sucrose

2006
Restraint stress modulates glucocorticoid receptors and nuclear factor kappa B in the cochlea.
    Neuroreport, 2006, Jun-26, Volume: 17, Issue:9

    Topics: Analysis of Variance; Animals; Blotting, Western; Cochlea; Corticosterone; Drug Interactions; Enzyme Inhibitors; Gene Expression Regulation; Immunohistochemistry; Male; Metyrapone; Mice; Mice, Inbred CBA; Mifepristone; Neurons; NF-kappa B; Receptors, Glucocorticoid; Restraint, Physical; Spiral Ganglion; Stress, Psychological; Time Factors

2006
Glucocorticoid receptor and nuclear factor-kappa B interactions in restraint stress-mediated protection against acoustic trauma.
    Endocrinology, 2006, Volume: 147, Issue:9

    Topics: Animals; Biological Transport; Cell Nucleus; Corticosterone; Hearing Loss, Noise-Induced; I-kappa B Proteins; Male; Metyrapone; Mice; Mice, Inbred CBA; Mifepristone; Neurons; NF-kappa B; Receptors, Glucocorticoid; Restraint, Physical; RNA, Messenger; Signal Transduction; Spiral Ganglion; Stress, Physiological

2006
Pharmacological management of Cushing's syndrome: an update.
    Arquivos brasileiros de endocrinologia e metabologia, 2007, Volume: 51, Issue:8

    Topics: Cushing Syndrome; Dopamine Antagonists; Hormone Antagonists; Humans; Hypothalamo-Hypophyseal System; Ketoconazole; Metyrapone; Mifepristone; Mitotane; Pituitary-Adrenal System; PPAR gamma; Somatostatin; Steroids

2007
Metyrapone and mifepristone reverse recognition memory loss induced by spontaneous morphine withdrawal in mice.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 102, Issue:4

    Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Glucocorticoids; Hormone Antagonists; Injections, Subcutaneous; Male; Memory; Memory Disorders; Metyrapone; Mice; Mifepristone; Morphine; Receptors, Glucocorticoid; Recognition, Psychology; Steroid 11-beta-Hydroxylase; Substance Withdrawal Syndrome; Time Factors

2008
Stress impairs reconsolidation of drug memory via glucocorticoid receptors in the basolateral amygdala.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, May-21, Volume: 28, Issue:21

    Topics: Amygdala; Analgesics, Opioid; Androstanols; Animals; Association Learning; Behavior, Animal; Conditioning, Operant; Corticosterone; Drug Administration Routes; Enzyme Inhibitors; Hormone Antagonists; Male; Memory Disorders; Metyrapone; Mifepristone; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reward; Stress, Psychological

2008
Cocaine decreases the expression of PSA-NCAM protein and attenuates long-term potentiation via glucocorticoid receptors in the rat dentate gyrus.
    The European journal of neuroscience, 2008, Volume: 27, Issue:11

    Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cocaine; Cocaine-Related Disorders; Corticosterone; Dentate Gyrus; Dopamine Uptake Inhibitors; Down-Regulation; Ki-67 Antigen; Long-Term Potentiation; Male; Memory; Memory Disorders; Metyrapone; Mifepristone; Mineralocorticoid Receptor Antagonists; Neural Cell Adhesion Molecule L1; Neurons; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sialic Acids; Spironolactone

2008
Tissue-specific difference in the molecular mechanisms for the development of acute insulin resistance after injury.
    Endocrinology, 2009, Volume: 150, Issue:1

    Topics: Acute Disease; Animals; Corticosterone; Fatty Acids, Nonesterified; Hemorrhage; Hormone Antagonists; Insulin; Insulin Resistance; Liver; Male; Metyrapone; Mifepristone; Muscle, Skeletal; Phosphoserine; Rats; Rats, Sprague-Dawley; Signal Transduction; Wounds and Injuries

2009
Stress at learning facilitates memory formation by regulating AMPA receptor trafficking through a glucocorticoid action.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:3

    Topics: Animals; Corticosterone; Glucocorticoids; Male; Maze Learning; Memory; Metyrapone; Mice; Mice, Inbred C57BL; Mifepristone; Protein Transport; Receptors, AMPA; Stress, Psychological

2010
Effects of endogenous glucocorticoids on allergic inflammation and T(H)1 /T(H)2 balance in airway allergic disease.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 103, Issue:6

    Topics: Animals; Bone Marrow; Cell Count; Concanavalin A; Corticosterone; Eosinophils; Glucocorticoids; Immunization; Inflammation; Interferon-gamma; Interleukin-4; Interleukin-5; Leukocyte Count; Lung; Lymphocyte Activation; Lymphocytes; Male; Metyrapone; Mice; Mice, Inbred BALB C; Mifepristone; Ovalbumin; Respiratory Hypersensitivity; Sneezing; Specific Pathogen-Free Organisms; Spleen; Th1 Cells; Th2 Cells

2009
Ischemic preconditioning attenuates gastric ischemia-reperfusion injury through involvement of glucocorticoids.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60 Suppl 7

    Topics: Adrenalectomy; Animals; Celiac Artery; Corticosterone; Enzyme Inhibitors; Gastric Mucosa; Hormone Antagonists; Ischemic Preconditioning; Male; Metyrapone; Mifepristone; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Reperfusion Injury; Severity of Illness Index; Steroid 11-beta-Hydroxylase; Stomach; Stomach Ulcer; Time Factors

2009
Anti-inflammatory effect of bee venom on antigen-induced arthritis in rabbits: influence of endogenous glucocorticoids.
    Journal of ethnopharmacology, 2010, Jul-06, Volume: 130, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antigens; Arthritis, Experimental; Bee Venoms; Dinoprostone; Glucocorticoids; Leukocyte Count; Metyrapone; Mifepristone; Rabbits

2010
Brief neck restraint stress enhances long-term potentiation and suppresses long-term depression in the dentate gyrus of the mouse.
    Brain research bulletin, 2011, Jul-15, Volume: 85, Issue:6

    Topics: Animals; Corticosterone; Dentate Gyrus; Enzyme Inhibitors; Hormone Antagonists; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Metyrapone; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Neck; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Restraint, Physical; Spironolactone; Synaptic Transmission

2011
Evidence for transcriptional regulation of the urea transporter in the gill of the Gulf toadfish, Opsanus beta.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2011, Volume: 160, Issue:2-3

    Topics: Animals; Antimetabolites; Base Sequence; Batrachoidiformes; Gene Expression Regulation; Gills; Hormone Antagonists; Hydrocortisone; Membrane Transport Proteins; Metyrapone; Mifepristone; Molecular Sequence Data; Phylogeny; Promoter Regions, Genetic; Receptors, Glucocorticoid; Spironolactone; Tissue Distribution; Transcription, Genetic; Urea; Urea Transporters

2011
Essential roles of endogenous glucocorticoids and TNF/TNFR1 in promoting bone-marrow eosinopoiesis in ovalbumin-sensitized, airway-challenged mice.
    Life sciences, 2014, Jan-14, Volume: 94, Issue:1

    Topics: Animals; Bone Marrow; Corticosterone; Eosinophilia; Eosinophils; Female; Glucocorticoids; Inflammation; Metyrapone; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mifepristone; Ovalbumin; Peritoneal Cavity; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha

2014
Corticosteroid-endocannabinoid loop supports decrease of fear-conditioned response in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:7

    Topics: Adrenal Cortex Hormones; Animals; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Modulators; Conditioning, Classical; Dexamethasone; Endocannabinoids; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Male; Metyrapone; Mifepristone; Mineralocorticoid Receptor Antagonists; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Glucocorticoid; Rimonabant; Spironolactone

2014
5-Hydroxytryptamine 1A (5HT1A) receptors mediate increases in plasma glucose independent of corticosterone.
    European journal of pharmacology, 2014, Dec-15, Volume: 745

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Corticosterone; Hypoglycemic Agents; Hypothalamus; Insulin; Male; Metyrapone; Mice; Mice, Inbred C57BL; Mifepristone; Piperidines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2014
Rapid Activation of Glucocorticoid Receptors in the Prefrontal Cortex Mediates the Expression of Contextual Conditioned Fear in Rats.
    Cerebral cortex (New York, N.Y. : 1991), 2016, Volume: 26, Issue:6

    Topics: Animals; Conditioning, Psychological; Corticosterone; Enzyme Inhibitors; Fear; Freezing Reaction, Cataleptic; Hormone Antagonists; Male; Metyrapone; Mifepristone; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone

2016
Corticosterone and dopamine D2/D3 receptors mediate the motivation for voluntary wheel running in C57BL/6J mice.
    Behavioural brain research, 2016, 09-15, Volume: 311

    Topics: Animals; Corticosterone; Dopamine Antagonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hormone Antagonists; Male; Memory; Metyrapone; Mice, Inbred C57BL; Mifepristone; Motivation; Nootropic Agents; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Glucocorticoid; Running; Sulpiride; Volition

2016
BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2017, Volume: 23, Issue:8

    Topics: 14-alpha Demethylase Inhibitors; ACTH-Secreting Pituitary Adenoma; Adenoma; Adolescent; Adrenalectomy; Adult; Aged; Antineoplastic Agents; Cabergoline; Comorbidity; Enzyme Inhibitors; Ergolines; Female; Follow-Up Studies; Hirsutism; Hormone Antagonists; Hormones; Humans; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Ketoconazole; Male; Metyrapone; Middle Aged; Mifepristone; Muscle Weakness; Muscular Atrophy; Neurosurgical Procedures; Obesity, Abdominal; Pituitary ACTH Hypersecretion; Pituitary Irradiation; Polycystic Ovary Syndrome; Retrospective Studies; Rosiglitazone; Somatostatin; Striae Distensae; Thiazolidinediones; Treatment Outcome; Tumor Burden; Young Adult

2017
Modulation of Rat 50-kHz Ultrasonic Vocalizations by Glucocorticoid Signaling: Possible Relevance to Reward and Motivation.
    The international journal of neuropsychopharmacology, 2018, 01-01, Volume: 21, Issue:1

    Topics: Amphetamine; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucocorticoids; Hormone Antagonists; Male; Metyrapone; Mifepristone; Motivation; Rats; Rats, Sprague-Dawley; Reward; Signal Transduction; Spironolactone; Ultrasonics; Vocalization, Animal

2018
The effects of stress, cortisol administration and cortisol inhibition on black sea bass (Centropristis striata) sex differentiation.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2019, Volume: 227

    Topics: Animals; Bass; Female; Hydrocortisone; Male; Metyrapone; Mifepristone; Sex Differentiation; Stress, Physiological

2019
Modern Management of Mild Autonomous Cortisol Secretion.
    Clinical pharmacology and therapeutics, 2019, Volume: 106, Issue:6

    Topics: 14-alpha Demethylase Inhibitors; Adrenal Cortex Neoplasms; Adrenal Insufficiency; Adrenalectomy; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 2; Disease Management; Dyslipidemias; Enzyme Inhibitors; Glucocorticoids; Hormone Antagonists; Humans; Hydrocortisone; Hypertension; Incidental Findings; Ketoconazole; Metyrapone; Mifepristone; Mortality; Obesity; Osteoporosis; Postoperative Hemorrhage; Risk; Saliva; Severity of Illness Index

2019