Compounds > metyrapone

metyrapone and fomepizole

metyrapone has been researched along with fomepizole in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Farrell, GC; Field, J; Frost, L; Mahoney, J; Tapner, M; Weltman, M1
Ding, X; Gonzalez, FJ; Liu, C; Zhuo, X1
Bortolato, S; Ferrara, R; Manno, M; Tolando, R; Zanovello, A1

Reviews

1 review(s) available for metyrapone and fomepizole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for metyrapone and fomepizole

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Halothane-induced liver injury in guinea-pigs: importance of cytochrome P450 enzyme activity and hepatic blood flow.
    Journal of gastroenterology and hepatology, 1996, Volume: 11, Issue:6

    Topics: Animals; Arteries; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Fomepizole; Genetic Predisposition to Disease; Guinea Pigs; Halothane; Liver; Liver Circulation; Male; Metyrapone; Microsomes, Liver; Necrosis; Portal System; Proadifen; Pyrazoles

1996
Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2a6: role in metabolic activation of nasal toxicants.
    Molecular pharmacology, 1996, Volume: 50, Issue:4

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Baculoviridae; Biotransformation; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Inhibitors; Fomepizole; Hempa; Humans; Immunoblotting; Male; Methoxsalen; Metyrapone; Mixed Function Oxygenases; Nitriles; Nitrophenols; Olfactory Mucosa; Pyrazoles; Rabbits; Rats; Rats, Wistar; Spodoptera; Substrate Specificity; Testosterone

1996
Bioactivation to free radicals and cytotoxicity of 1,1-dichloro-1-fluoroethane (HCFC-141b).
    Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Fomepizole; Free Radicals; Glutathione; Hepatocytes; Isoenzymes; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Metyrapone; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pyrazoles; Pyridines; Rats; Rats, Wistar; Troleandomycin

2001