metyrapol has been researched along with etomidate in 2 studies
| Studies (metyrapol) | Trials (metyrapol) | Recent Studies (post-2010) (metyrapol) | Studies (etomidate) | Trials (etomidate) | Recent Studies (post-2010) (etomidate) |
|---|---|---|---|---|---|
| 18 | 0 | 1 | 2,071 | 401 | 576 |
| Protein | Taxonomy | metyrapol (IC50) | etomidate (IC50) |
|---|---|---|---|
| Cytochrome P450 11B1, mitochondrial | Homo sapiens (human) | 0.0005 | |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | 0.0009 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, ML; Hahner, S; Hammerschmidt, F; Peric-Simov, B; Schirbel, A; Zolle, IM | 1 |
| Atucha, E; Berger, ML; Hammerschmidt, F; Sieghart, W; Zolle, I | 1 |
2 other study(ies) available for metyrapol and etomidate
| Article | Year |
|---|---|
New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues.
Topics: Adrenal Cortex; Animals; Binding Sites; Etomidate; Humans; Hydroxylation; Iodine Radioisotopes; Kinetics; Male; Molecular Structure; Rats; Rats, Wistar; Stereoisomerism; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship | 2008 |
Structure-activity relationship of etomidate derivatives at the GABA(A) receptor: Comparison with binding to 11beta-hydroxylase.
Topics: Anesthetics, Intravenous; Animals; Binding Sites; Chemistry, Pharmaceutical; Drug Design; Etomidate; Inhibitory Concentration 50; Male; Models, Chemical; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereoisomerism; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship | 2009 |