metylperon has been researched along with clozapine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Christensson, E; Egbe, P; Engel, J; Gustafsson, B | 1 |
| Matsubara, S; Meltzer, HY | 1 |
| Gudelsky, GA; Koenig, JI; Meltzer, HY; Nash, JF | 1 |
| Gudelsky, GA; Meltzer, HY; Nash, JF | 1 |
| Hippius, H; Klages, U; Müller-Spahn, F | 1 |
| Evans, DL; Figur, LM; Lahti, RA; Stratman, NC | 1 |
| Dai, J; Ichikawa, J; Li, Z; Meltzer, HY | 1 |
| Baker, LE; Meltzer, HY; Prus, AJ | 1 |
| Dahl, SG; Hjerde, E; Sylte, I | 1 |
| Bobo, WV; Jayathilake, K; Lee, MA; Meltzer, HY | 2 |
| Alam, R; Gadhia, S; Röhricht, F; Willis, M | 1 |
1 review(s) available for metylperon and clozapine
| Article | Year |
|---|---|
[Atypical neuroleptics, pharmacology and clinical importance].
Topics: Animals; Antipsychotic Agents; Brain; Butyrophenones; Clinical Trials as Topic; Clozapine; Humans; Psychotic Disorders; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin | 1993 |
1 trial(s) available for metylperon and clozapine
| Article | Year |
|---|---|
Melperone, an aytpical antipsychotic drug with clozapine-like effect on plasma prolactin: contrast with typical neuroleptics.
Topics: Adult; Antipsychotic Agents; Butyrophenones; Clozapine; Female; Humans; Male; Mental Disorders; Prolactin; Sex Factors | 2009 |
12 other study(ies) available for metylperon and clozapine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Amperozide and conditioned behaviour in rats: potentiation by classical neuroleptics and alpha-methylparatyrosine.
Topics: alpha-Methyltyrosine; Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Butyrophenones; Chlorpromazine; Clozapine; Conditioning, Operant; Drug Synergism; Female; Food; Haloperidol; Male; Methyltyrosines; Piperazines; Psychotropic Drugs; Rats; Rats, Inbred Strains; Reinforcement Schedule | 1990 |
Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Butyrophenones; Cerebral Cortex; Chlorpromazine; Clozapine; Dibenzazepines; Dibenzothiazepines; Down-Regulation; Flupenthixol; Kinetics; Loxapine; Male; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiro Compounds; Time Factors | 1989 |
Melperone and clozapine: neuroendocrine effects of atypical neuroleptic drugs.
Topics: Animals; Antipsychotic Agents; Arcuate Nucleus of Hypothalamus; Butyrophenones; Clozapine; Corticosterone; Dibenzazepines; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Male; Median Eminence; Neurons; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1989 |
Antagonism of serotonin receptor mediated neuroendocrine and temperature responses by atypical neuroleptics in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Body Temperature; Butyrophenones; Chlorpromazine; Clozapine; Corticosterone; Haloperidol; Male; Neurosecretory Systems; Pyrazines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1988 |
Dopamine D4 versus D2 receptor selectivity of dopamine receptor antagonists: possible therapeutic implications.
Topics: Animals; Apomorphine; Butyrophenones; Cell Line; Chlorpromazine; Clozapine; Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Raclopride; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D4; Salicylamides; Trifluoperazine | 1993 |
Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonism.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Butyrophenones; Clozapine; Dibenzothiazepines; Dopamine; Haloperidol; Isoxazoles; Male; Microdialysis; Nucleus Accumbens; Piperidines; Prefrontal Cortex; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1 | 2002 |
Discriminative stimulus properties of 1.25 and 5.0 mg/kg doses of clozapine in rats: examination of the role of dopamine, serotonin, and muscarinic receptor mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Butyrophenones; Clozapine; Discrimination, Psychological; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Fluorobenzenes; Generalization, Stimulus; Haloperidol; Male; Muscarinic Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Trihexyphenidyl | 2004 |
Atypical and typical antipsychotic drug interactions with the dopamine D2 receptor.
Topics: Antipsychotic Agents; Binding Sites; Butyrophenones; Clozapine; Drug Interactions; Halogens; Humans; Ligands; Loxapine; Molecular Structure; Receptors, Dopamine D2 | 2005 |
Changes in weight and body mass index during treatment with melperone, clozapine and typical neuroleptics.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Body Mass Index; Body Weight; Butyrophenones; Clozapine; Female; Humans; Male; Schizophrenia; Time Factors | 2010 |
Auditing clinical outcomes after introducing off-licence prescribing of atypical antipsychotic melperone for patients with treatment refractory schizophrenia.
Topics: Adult; Antipsychotic Agents; Butyrophenones; Clozapine; Female; Follow-Up Studies; Humans; Male; Medical Audit; Middle Aged; Off-Label Use; Prospective Studies; Quality of Life; Schizophrenia; Severity of Illness Index; Treatment Outcome; Young Adult | 2012 |