metronidazole and tigecycline

metronidazole has been researched along with tigecycline in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (19.35)	29.6817
2010's	22 (70.97)	24.3611
2020's	3 (9.68)	2.80

Authors

Authors	Studies
Galang, MA; Gerding, DN; Hecht, DW; Johnson, S; Osmolski, JR; Sambol, SP	1
Lombardo, F; Obach, RS; Waters, NJ	1
Betriu, C; Culebras, E; Gómez, M; López, F; Picazo, JJ; Rodríguez-Avial, I	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Bavari, S; Bowlin, TL; Butler, MM; Moir, DT; Panchal, RG; Peet, NP; Shinabarger, DL; Williams, JD	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brook, I	2
Mazzei, T; Novelli, A	1
Hsueh, PR; Huang, YT; Liao, CH; Liu, CY; Lu, CL; Wang, HP	1
Hsueh, PR; Lee, PI; Yang, JC	1
Babinchak, T; Leister, H; Pasternak, J; Poirier, A; Towfigh, S	1
Antoniadou, A; Armaganidis, A; Dimopoulou, I; Kopterides, P; Papadomichelakis, E; Papageorgiou, C; Tsangaris, I	1
Jacobus, NV; McDermott, LA; Snydman, DR	1
Baban, TA; El-Herte, RI; Kanj, SS	1
Barbato, M; Consorte, A; D'Antonio, D; Mazzotta, E; Parruti, G; Polilli, E; Savini, V; Sozio, F; Ursini, T	1
Babinchak, T; Leister-Tebbe, H; McGovern, PC; Pedersen, R; Qvist, N; Warren, B; Zito, ET	1
Bossé, D; Cantin, AM; Lemire, C; Ménard, F; Ruel, J; Valiquette, L	1
Alffenaar, JW; Alsaad, N; de Lange, WC; Kosterink, JG; van Altena, R; van der Werf, TS; Wilffert, B	1
Fortier, LC; Garneau, JR; Valiquette, L	1
Alp, E; Berk, E; Çetin, M; Gürsoy, Ş; Kaynar, L; Kılıç, H; Metan, G; Türe, Z	1
Belyaev, O; Chromik, AM; Deleites, C; Herzog, T; Uhl, W	1
Dezsenyi, B; Fried, K; Gergely Szabo, B; Kadar, B; Kamotsay, K; Kunovszki, P; Nikolova, R; Prinz, G; Szidonia Lenart, K	1
Cheng, JW; Kong, F; Kudinha, T; Liao, JW; Xiao, M; Xu, YC; Yang, QW; Yu, SY; Zhou, ML	1
Brodsky, D; Jackson, K; Nitzan, O; Pastukh, N; Peretz, A; Tkhawkho, L	1
Bishop, EJ; Botha, J; Kelley, PG; Marshall, C; Metcalfe, J; Tiruvoipati, R	1
AlSaeed, T; Fouad, AF; Melo, MA; Nosrat, A; Romberg, E; Wang, P; Xu, H	1
AlAzmi, A; AlHashem, G; Jamal, W; Khodakhast, FB; Rotimi, VO; Sόki, J	1
Leahy, RG; Serio, AW; Tanaka, SK; Traczewski, MM; Wright, K	1
Deng, T; Kong, W; Li, S; Shu, Y; Wu, Y	1

Reviews

7 review(s) available for metronidazole and tigecycline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Treatment of anaerobic infection. Expert review of anti-infective therapy, 2007, Volume: 5, Issue:6 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Chloramphenicol; Clindamycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Metronidazole; Microbial Sensitivity Tests; Minocycline; Negative-Pressure Wound Therapy; Penicillins; Tigecycline	2007
[Pharmacological rationale for choice of antibiotics for intraabdominal infections]. Le infezioni in medicina, 2008, Volume: 16 Suppl 1 Topics: Abdominal Abscess; Acetamides; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactams; Digestive System Diseases; Drug Therapy, Combination; Fluoroquinolones; Humans; Linezolid; Metronidazole; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Peritonitis; Sepsis; Tigecycline; Treatment Outcome; Virginiamycin	2008
Recurrent refractory Clostridium difficile colitis treated successfully with rifaximin and tigecycline: a case report and review of the literature. Scandinavian journal of infectious diseases, 2012, Volume: 44, Issue:3 Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Colitis; Drug Therapy, Combination; Female; Humans; Metronidazole; Minocycline; Recurrence; Rifamycins; Rifaximin; Tigecycline; Treatment Outcome; Vancomycin	2012
Potential antimicrobial agents for the treatment of multidrug-resistant tuberculosis. The European respiratory journal, 2014, Volume: 43, Issue:3 Topics: Anti-Infective Agents; Antitubercular Agents; Chemistry, Pharmaceutical; Clinical Trials as Topic; Disulfiram; Doxycycline; Drug Design; Humans; Metronidazole; Minocycline; Mycobacterium tuberculosis; Phenothiazines; Tigecycline; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Multidrug-Resistant	2014
Spectrum and treatment of anaerobic infections. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2016, Volume: 22, Issue:1 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; beta-Lactamase Inhibitors; Carbapenems; Cefoxitin; Chloramphenicol; Clindamycin; Drug Resistance, Bacterial; Humans; Metronidazole; Minocycline; Penicillins; Tigecycline	2016
Efficacy, safety, and tolerability of antimicrobial agents for complicated intra-abdominal infection: a systematic review and network meta-analysis. BMC infectious diseases, 2023, Apr-21, Volume: 23, Issue:1 Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Humans; Intraabdominal Infections; Meropenem; Metronidazole; Network Meta-Analysis; Tazobactam; Tigecycline	2023

Trials

2 trial(s) available for metronidazole and tigecycline

Article	Year
A multicentre, open-label, randomized comparative study of tigecycline versus ceftriaxone sodium plus metronidazole for the treatment of hospitalized subjects with complicated intra-abdominal infections. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2010, Volume: 16, Issue:8 Topics: Abdomen; Anti-Infective Agents; Bacteria; Bacterial Infections; Ceftriaxone; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Male; Metronidazole; Middle Aged; Minocycline; Tigecycline; Treatment Outcome	2010
Efficacy of tigecycline versus ceftriaxone plus metronidazole for the treatment of complicated intra-abdominal infections: results from a randomized, controlled trial. Surgical infections, 2012, Volume: 13, Issue:2 Topics: Adult; Aged; Anti-Bacterial Agents; Ceftriaxone; Drainage; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Intraabdominal Infections; Male; Metronidazole; Middle Aged; Minocycline; Tigecycline; Treatment Outcome	2012

Article

Year

A multicentre, open-label, randomized comparative study of tigecycline versus ceftriaxone sodium plus metronidazole for the treatment of hospitalized subjects with complicated intra-abdominal infections.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2010, Volume: 16, Issue:8

Topics: Abdomen; Anti-Infective Agents; Bacteria; Bacterial Infections; Ceftriaxone; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Male; Metronidazole; Middle Aged; Minocycline; Tigecycline; Treatment Outcome

2010

Efficacy of tigecycline versus ceftriaxone plus metronidazole for the treatment of complicated intra-abdominal infections: results from a randomized, controlled trial.

Surgical infections, 2012, Volume: 13, Issue:2

Topics: Adult; Aged; Anti-Bacterial Agents; Ceftriaxone; Drainage; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Intraabdominal Infections; Male; Metronidazole; Middle Aged; Minocycline; Tigecycline; Treatment Outcome

2012

Other Studies

22 other study(ies) available for metronidazole and tigecycline

Article	Year
In vitro activities of 15 antimicrobial agents against 110 toxigenic clostridium difficile clinical isolates collected from 1983 to 2004. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8 Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous; Humans; Microbial Sensitivity Tests; United States	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7 Topics: Anti-Bacterial Agents; Bacteroides; Bacteroides fragilis; Bacteroides Infections; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Spain; Species Specificity; Time Factors	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9 Topics: Anti-Bacterial Agents; Gram-Negative Aerobic Bacteria; Gram-Positive Bacteria; Indoles; Microbial Sensitivity Tests	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Severe and refractory Clostridium difficile infection successfully treated with tigecycline and metronidazole. International journal of antimicrobial agents, 2010, Volume: 35, Issue:3 Topics: Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Female; Humans; Metronidazole; Microbial Sensitivity Tests; Middle Aged; Minocycline; Tigecycline	2010
In vitro activity of nemonoxacin, tigecycline, and other antimicrobial agents against Helicobacter pylori isolates in Taiwan, 1998-2007. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2010, Volume: 29, Issue:11 Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Clarithromycin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gemifloxacin; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Mutation; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Sequence Analysis, Protein; Taiwan; Tetracyclines; Tigecycline	2010
Failure of tigecycline to treat severe Clostridium difficile infection. Anaesthesia and intensive care, 2010, Volume: 38, Issue:4 Topics: Aged; Anti-Bacterial Agents; Critical Care; Drug Resistance, Bacterial; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Humans; Immunoglobulins, Intravenous; Male; Metronidazole; Minocycline; Severity of Illness Index; Tigecycline; Treatment Failure; Vancomycin	2010
In vitro activity of ceftaroline against a broad spectrum of recent clinical anaerobic isolates. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1 Topics: Anti-Bacterial Agents; Aza Compounds; Bacteria, Anaerobic; Ceftaroline; Ceftriaxone; Cephalosporins; Clindamycin; Fluoroquinolones; Imipenem; Metronidazole; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Quinolines; Tigecycline	2011
Successful salvage therapy with Daptomycin for osteomyelitis caused by methicillin-resistant Staphylococcus aureus in a renal transplant recipient with Fabry-Anderson disease. Annals of clinical microbiology and antimicrobials, 2012, Mar-11, Volume: 11 Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Calcaneus; Daptomycin; Fabry Disease; Heel; Humans; Kidney Transplantation; Male; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Metronidazole; Minocycline; Osteomyelitis; Renal Insufficiency; Salvage Therapy; Staphylococcal Infections; Teicoplanin; Tigecycline; Tomography, X-Ray Computed	2012
Severe anaphylaxis caused by orally administered vancomycin to a patient with Clostridium difficile infection. Infection, 2013, Volume: 41, Issue:2 Topics: Administration, Oral; Adult; Anaphylaxis; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cystic Fibrosis; Diarrhea; Enterocolitis, Pseudomembranous; Humans; Male; Metronidazole; Minocycline; Severity of Illness Index; Tigecycline; Vancomycin	2013
Prevention of Clostridium difficile spore formation by sub-inhibitory concentrations of tigecycline and piperacillin/tazobactam. BMC infectious diseases, 2014, Jan-15, Volume: 14 Topics: Anti-Bacterial Agents; Ciprofloxacin; Clostridioides difficile; Humans; Metronidazole; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Ribotyping; Spores, Bacterial; Tazobactam; Tigecycline; Vancomycin	2014
Tigecycline for the treatment of Clostridium difficile infection refractory to metronidazole in haematopoietic stem cell transplant recipients. Journal of chemotherapy (Florence, Italy), 2015, Volume: 27, Issue:6 Topics: Adult; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Drug Resistance, Bacterial; Fecal Microbiota Transplantation; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Metronidazole; Middle Aged; Minocycline; Retrospective Studies; Tigecycline; Treatment Outcome; Young Adult	2015
[Clostridium difficile in visceral surgery]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2015, Volume: 86, Issue:8 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Cohort Studies; Cross Infection; Cross-Sectional Studies; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Female; Fidaxomicin; Germany; Hospital Mortality; Humans; Incidence; Intensive Care Units; Male; Metronidazole; Middle Aged; Minocycline; Patient Readmission; Retrospective Studies; Survival Rate; Tigecycline; Vancomycin; Young Adult	2015
Use of intravenous tigecycline in patients with severe Clostridium difficile infection: a retrospective observational cohort study. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2016, Volume: 22, Issue:12 Topics: Administration, Intravenous; Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Colectomy; Enterocolitis, Pseudomembranous; Female; Humans; Intraabdominal Infections; Male; Metronidazole; Middle Aged; Minocycline; Recurrence; Retrospective Studies; Sepsis; Tigecycline; Treatment Outcome; Vancomycin	2016
High in vitro activity of fidaxomicin against Clostridium difficile isolates from a university teaching hospital in China. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2018, Volume: 51, Issue:3 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Toxins; China; Clostridioides difficile; Clostridium Infections; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Fidaxomicin; Fluoroquinolones; Genes, Bacterial; Hospitals, Teaching; Hospitals, University; Humans; Metronidazole; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Multilocus Sequence Typing; Ribotyping; Tigecycline; Vancomycin	2018
Antimicrobial susceptibility of Clostridium difficile isolates in Israel. Journal of global antimicrobial resistance, 2017, Volume: 10 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Drug Combinations; Feces; Hospitals; Humans; Israel; Metronidazole; Microbial Sensitivity Tests; Ribotyping; Tigecycline; Vancomycin	2017
The outcome of patients with severe and severe-complicated Clostridium difficile infection treated with tigecycline combination therapy: a retrospective observational study. Internal medicine journal, 2018, Volume: 48, Issue:6 Topics: Administration, Intravenous; Aged; Aged, 80 and over; Anti-Bacterial Agents; Australia; Clostridioides difficile; Clostridium Infections; Cross Infection; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Middle Aged; Minocycline; Retrospective Studies; Tigecycline; Treatment Outcome; Vancomycin	2018
Antibacterial Efficacy and Discoloration Potential of Endodontic Topical Antibiotics. Journal of endodontics, 2018, Volume: 44, Issue:7 Topics: Administration, Topical; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ciprofloxacin; Dental Pulp Cavity; Enterococcus faecalis; Fusobacterium nucleatum; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Metronidazole; Microbial Sensitivity Tests; Minocycline; Porphyromonas gingivalis; Regenerative Endodontics; Root Canal Therapy; Streptococcus intermedius; Tigecycline; Tissue Scaffolds; Tooth Discoloration	2018
Prevalence and antimicrobial susceptibility of enterotoxigenic extra-intestinal Bacteroides fragilis among 13-year collection of isolates in Kuwait. BMC microbiology, 2020, 01-15, Volume: 20, Issue:1 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Toxins; Bacteroides fragilis; Bacteroides Infections; Cefoxitin; Clindamycin; Drug Resistance, Bacterial; Feces; Female; Humans; Imipenem; Kuwait; Male; Meropenem; Metronidazole; Microbial Sensitivity Tests; Piperacillin; Prevalence; Prospective Studies; Respiratory Tract Infections; Sepsis; Tigecycline; Wound Infection	2020
Activity of omadacycline in vitro against Clostridioides difficile and preliminary efficacy assessment in a hamster model of C. difficile-associated diarrhoea. Journal of global antimicrobial resistance, 2022, Volume: 30 Topics: Animals; Anti-Bacterial Agents; Clindamycin; Clostridioides; Clostridioides difficile; Cricetinae; Diarrhea; Metronidazole; Tetracyclines; Tigecycline; Vancomycin	2022