metronidazole and simvastatin

metronidazole has been researched along with simvastatin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (14.29)29.6817
2010's11 (78.57)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bloomer, WD; Papadopoulou, MV; Rosenzweig, HS1
Dziubla, TD; Peyyala, R; Puleo, DA; Sundararaj, SC; Thomas, MV1
Fan, C; Jin, X; Liu, Y; Lv, L; Ou, M; Wu, G; Ye, H; Zhang, X; Zhou, Y1
Orellana, BR; Puleo, DA1
Asl Aminabadi, N; Jamali, Z; Najafpour, E; Samiei, M; Satrab, S; Shirazi, S1
Agheli, S; Aminabadi, NA; Huang, B; Jamali, Z; Samiei, M; Shirazi, S1
Alam, M; Farooq, U; Iqbal, Z; Jain, P; Kuruniyan, MS; Mirza, MA; Nainwal, LM; Poonkuzhi, NP1

Reviews

1 review(s) available for metronidazole and simvastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for metronidazole and simvastatin

ArticleYear
A randomized trial of direct pulp capping in primary molars using MTA compared to 3Mixtatin: a novel pulp capping biomaterial.
    International journal of paediatric dentistry, 2016, Volume: 26, Issue:4

    Topics: Aluminum Compounds; Anti-Bacterial Agents; Biocompatible Materials; Calcium Compounds; Chi-Square Distribution; Child; Child, Preschool; Dental Pulp Capping; Dental Pulp Diseases; Dental Pulp Exposure; Drug Combinations; Female; Follow-Up Studies; Humans; Iran; Male; Materials Testing; Metronidazole; Molar; Oxides; Pilot Projects; Pulp Capping and Pulpectomy Agents; Root Canal Filling Materials; Root Resorption; Silicates; Simvastatin; Tooth, Deciduous; Treatment Outcome; Zinc Oxide-Eugenol Cement

2016
A Randomized Trial Using 3Mixtatin Compared to MTA in Primary Molars with Inflammatory Root Resorption: A Novel Endodontic Biomaterial.
    The Journal of clinical pediatric dentistry, 2016, Volume: 40, Issue:2

    Topics: Aluminum Compounds; Anti-Bacterial Agents; Calcium Compounds; Cefixime; Child; Child, Preschool; Ciprofloxacin; Crowns; Dental Fistula; Dental Pulp Diseases; Dental Restoration, Permanent; Drug Combinations; Female; Follow-Up Studies; Humans; Male; Metronidazole; Molar; Oxides; Periapical Diseases; Pulp Capping and Pulpectomy Agents; Pulpectomy; Root Canal Filling Materials; Root Resorption; Silicates; Simvastatin; Tooth, Deciduous; Treatment Outcome; Zinc Oxide-Eugenol Cement

2016

Other Studies

11 other study(ies) available for metronidazole and simvastatin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The antitubercular activity of various nitro(triazole/imidazole)-based compounds.
    Bioorganic & medicinal chemistry, 2017, 11-01, Volume: 25, Issue:21

    Topics: Animals; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; Imidazoles; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Structure-Activity Relationship; Triazoles

2017
Design of a multiple drug delivery system directed at periodontitis.
    Biomaterials, 2013, Volume: 34, Issue:34

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Cellulose; Delayed-Action Preparations; Doxycycline; Drug Design; Humans; Ketoprofen; Metronidazole; Models, Theoretical; Periodontitis; Poloxamer; Simvastatin

2013
Bi-functionalization of a calcium phosphate-coated titanium surface with slow-release simvastatin and metronidazole to provide antibacterial activities and pro-osteodifferentiation capabilities.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Anti-Bacterial Agents; Calcium Phosphates; Cell Adhesion; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Coated Materials, Biocompatible; Delayed-Action Preparations; Disk Diffusion Antimicrobial Tests; Humans; Kinetics; Mesenchymal Stem Cells; Metronidazole; Osteogenesis; Prostheses and Implants; Simvastatin; Surface Properties; Titanium

2014
Tailored sequential drug release from bilayered calcium sulfate composites.
    Materials science & engineering. C, Materials for biological applications, 2014, Volume: 43

    Topics: Calcium Sulfate; Drug Delivery Systems; Drug Liberation; Metronidazole; Simvastatin; X-Ray Microtomography

2014
    Combinatorial chemistry & high throughput screening, 2022, Volume: 25, Issue:13

    Topics: Anti-Bacterial Agents; Celecoxib; Doxycycline; Humans; Hydroxyapatites; Matrix Metalloproteinase 13; Matrix Metalloproteinase 8; Matrix Metalloproteinase Inhibitors; Metronidazole; Minocycline; Molecular Docking Simulation; Osteopontin; Periodontitis; Simvastatin

2022