Compounds > metronidazole

metronidazole and pa 824

metronidazole has been researched along with pa 824 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Anderson, SW; Arain, TM; Baker, WR; Barry, CE; Kreiswirth, BN; Langhorne, MH; McMurray, DN; Sherman, DR; Stover, CK; Towell, JA; VanDevanter, DR; Warrener, P; Yuan, Y1
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S1
Barry, CE; Boshoff, HI; Dowd, CS; Jiricek, J; Keller, TH; Kim, P; Manjunatha, UH; Patel, S; Singh, R; Zhang, L1
Fairlamb, AH; Oza, SL; Patterson, S; Read, KD; Sokolova, AY; Wyllie, S1
Bloomer, WD; Kaiser, M; Papadopoulou, MV; Rosenzweig, HS1
Ang, CW; Avery, VM; Blaskovich, MAT; Butler, MS; Cooper, MA; Debnath, A; Hahn, HJ; Jarrad, AM; Jones, AJ; Karoli, T; Pelingon, R; Sykes, ML; Tan, L; West, NP; Woods, K1
Chen, J; Ding, C; Doyle, T; Duncan, L; Ebright, RH; He, S; Lin, W; Liu, Y; Lynch, AS; Ma, Z; Molodtsov, V; Nguyen, P; Pulse, M; Robertson, GT; Wang, H; Weiss, WJ; Xu, X; Yuan, Y; Zhuang, Z1
Diao, C; Liang, L; Liu, X; Wang, L; Xu, Y; Zhang, J; Zhang, S1

Other Studies

8 other study(ies) available for metronidazole and pa 824

ArticleYear
A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis.
    Nature, 2000, Jun-22, Volume: 405, Issue:6789

    Topics: Animals; Antitubercular Agents; Bacterial Proteins; Drug Resistance, Microbial; Drug Resistance, Multiple; Guinea Pigs; Lipids; Metronidazole; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Structure-Activity Relationship; Tuberculosis

2000
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen

2007
Structure-activity relationships of antitubercular nitroimidazoles. 1. Structural features associated with aerobic and anaerobic activities of 4- and 5-nitroimidazoles.
    Journal of medicinal chemistry, 2009, Mar-12, Volume: 52, Issue:5

    Topics: Aerobiosis; Anaerobiosis; Antitubercular Agents; Kinetics; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Nitroreductases; Oxazines; Stereoisomerism; Structure-Activity Relationship

2009
Cross-resistance to nitro drugs and implications for treatment of human African trypanosomiasis.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Animals; Cell Line; Drug Resistance; Eflornithine; Humans; Mice; Nifurtimox; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2010
The antitrypanosomal and antitubercular activity of some nitro(triazole/imidazole)-based aromatic amines.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Amines; Antitubercular Agents; Dose-Response Relationship, Drug; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Parasitic Sensitivity Tests; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi

2017
Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity.
    Journal of medicinal chemistry, 2018, 12-27, Volume: 61, Issue:24

    Topics: Animals; Antiparasitic Agents; Antitubercular Agents; Caco-2 Cells; Drug Design; Drug Evaluation, Preclinical; Drug Stability; Entamoeba histolytica; Giardia lamblia; Humans; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Nitroimidazoles; Structure-Activity Relationship

2018
Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens.
    Journal of medicinal chemistry, 2022, 03-24, Volume: 65, Issue:6

    Topics: Anaerobiosis; DNA-Directed RNA Polymerases; Helicobacter Infections; Helicobacter pylori; Humans; Nitroimidazoles; Rifamycins

2022
LC-MS/MS method for the simultaneous determination of PA-824, moxifloxacin and pyrazinamide in rat plasma and its application to pharmacokinetic study.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 97

    Topics: Animals; Chromatography, Liquid; Drug Interactions; Fluoroquinolones; Limit of Detection; Metronidazole; Moxifloxacin; Nitroimidazoles; Plasma; Pyrazinamide; Rats; Tandem Mass Spectrometry

2014