metronidazole and misonidazole

metronidazole has been researched along with misonidazole in 77 studies

Research

Studies (77)

Timeframe	Studies, this research(%)	All Research%
pre-1990	68 (88.31)	18.7374
1990's	8 (10.39)	18.2507
2000's	1 (1.30)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Levin, VA	1
Chan, YW; Cyr, JE; Linder, KE; Malley, MF; Nowotnik, DP; Nunn, AD	1
Denny, WA; Hay, MP; Moselen, JW; Palmer, BD; Wilson, WR	1
Karim, AB	1
Chapman, JD	1
Adams, GE; Clarke, ED; Gray, P; Jacobs, RS; Parrick, J; Smithen, CE; Stratford, IJ; Wallace, RG; Wardman, P; Watts, ME	1
Arnott, SJ	1
Chomiczewski, J; Gałkiewicz, E; Górski, T; Pyziak, M	1
Fowler, JF	1
Hirst, DG; Hobson, B; Vojnovic, B	1
Conroy, PJ; Von Burg, R	1
Olive, PL	2
Cheng, CC; Kimler, BF; Mansfield, CM; McDonald, T; Podrebarac, EG	1
Brückner, V	1
Uma Devi, P; Veena, K	1
Clarke, ED; Wardman, P	1
Adomat, H; Chaplin, DJ; Farrell, NP; Skov, KA	1
Church, DL; Laishley, EJ; Rabin, HR	1
Bazin, M; Moreno, G; Salet, C; Santus, R	1
Chignell, CF; Moore, DE; Motten, AG; Sik, RH	1
Dischino, DD; Jerabek, PA; Kilbourn, MR; Patrick, TB; Welch, MJ	1
Harman, L; Mason, RP; Motten, A; Rao, DN; Schreiber, J	1
Gutin, PH; Nelson, DF; Saunders, WM; Sheline, GE; Urtasun, RC	1
Arimizu, N; Fujimoto, S; Kobayashi, K; Kokubun, M; Miyoshi, T; Mori, T; Ohta, M; Okui, K; Shrestha, RD	1
Arimatsu, N; Fujimoto, S; Kiuchi, S; Kobayashi, K; Kokubun, M; Miyoshi, T; Mori, T; Ohta, M; Okui, K; Shresta, RD	1
Coleman, CN	1
Dische, S	1
Arimizu, N; Fujimoto, S; Kokubun, M; Miyoshi, T; Mori, T; Ohta, M; Okui, K; Shrestha, RD	1
Edwards, DI; Tocher, JH	1
Mason, RP; Rao, DN	1
Moore, DE	2
Edwards, DI; Knight, RC; Zahoor, A	1
Wideröe, R	1
Salwińska, E; Suwiński, J; Watras, J; Wideł, M	1
Noker, PE; Simpson-Herren, L; Wagoner, SD	1
Adomat, H; Farrell, NP; Skov, KA	1
Michaels, HB	1
Lafleur, MV; Loman, H; Pluijmackers-Westmijze, EJ	1
Hodgkiss, RJ	1
Chu, F; Hilaris, BS; Kim, JH; Nori, D	1
Bara, A; Mustea, I; Postescu, ID	1
Irvin, CG; Neaderland, MH; Rockwell, S	1
Battistella, R; McClelland, RA; Michaels, HB; Rauth, AM	1
Gutin, PH; Phillips, TL; Wara, WM; Wilson, CB	1
Lafleur, MV; Loman, H	1
Agboola, O; Feldstein, ML; Mielke, B; Miller, JD; Partington, J; Russell, DB; Tanasichuk, H; Urtasun, R	1
Kehrberg, G; Moldenhauer, H; Rose, H; Saul, G; Wolf, G	1
Lubas, B; Sułkowska, A; Wilczok, T	2
Dar'ialova, SL; Kiseleva, ES	1
Avigliano, L; Fielden, EM; Finazzi-Agrò, A; O'Neill, P	1
Siemann, DW	1
Rauth, AM	1
Ide, H; Kagiya, T; Nishimoto, S; Wada, T	1
Grdina, DJ; Mian, TA; Theiss, JC	1
Edwards, DI; Knight, RC; Knox, RJ	1
Goldman, P; Koch, RL; Sudlow, G; Yeung, TC	1
Kapp, DS; Rockwell, S	1
Twentyman, P; Workman, P	1
Adams, GE; Clarke, C; Rajaratnam, S; Stratford, IJ	1
Adams, GE; Rajaratnam, S; Stratford, IJ	1
Mahood, JS; Willson, RL	1
Krishnan, D; Singh, DR	1
Priseman, SJ; Prosser, JS	1
Hesketh, LC; Prosser, JS	1
Adams, GE; Biaglow, JE; Fielden, EM; Jacobson, B	1
Allen, N	1
Fielden, EM; Millar, BC; Steele, JJ	1
Bara, A; Mustea, I	1
Tannock, IF	2
Adams, GE; al-Kazwini, AT; Fielden, EM; Naylor, MA; O'Neill, P	1
Higuchi, T; Ilgan, S; Kim, EE; Liu, CW; Oh, CS; Podoloff, DA; Yang, DJ; Zareneyrizi, F	1
Denekamp, J; Harris, SR; Michael, BD	1
Ballinger, JR; Hsue, V; Rauth, AM	1

Reviews

7 review(s) available for metronidazole and misonidazole

Article	Year
Hypoxic sensitizers--implications for radiation therapy. The New England journal of medicine, 1979, Dec-27, Volume: 301, Issue:26 Topics: Animals; Female; Glioblastoma; Humans; Metronidazole; Misonidazole; Neoplasms; Oxygen Consumption; Radiation-Sensitizing Agents; Recurrence; Uterine Cervical Neoplasms	1979
Advances in radiotherapy. The Practitioner, 1978, Volume: 221, Issue:1324 Topics: Fast Neutrons; Humans; Hyperbaric Oxygenation; Metronidazole; Misonidazole; Neoplasms; Neutrons; Particle Accelerators; Radiation-Sensitizing Agents; Radiotherapy	1978
Recent and current investigations of radiation therapy of malignant gliomas. Seminars in oncology, 1986, Volume: 13, Issue:1 Topics: Brachytherapy; Brain; Brain Neoplasms; Bromodeoxyuridine; Carmustine; Glioma; Helium; Humans; Hyperbaric Oxygenation; Hyperthermia, Induced; Mesons; Metronidazole; Middle Aged; Misonidazole; Neon; Neutrons; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy, High-Energy	1986
Hypoxic cell radiosensitizers: expectations and progress in drug development. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:2 Topics: Clinical Trials as Topic; Combined Modality Therapy; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2 Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nimorazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
[Modification of the radiation effects for overcoming radiation-resistant hypoxic tumor tissue]. Radiobiologia, radiotherapia, 1983, Volume: 24, Issue:5 Topics: Amifostine; Animals; Central Nervous System Diseases; Dogs; Humans; Hyperthermia, Induced; In Vitro Techniques; Intestines; Lymphocytes; Metronidazole; Mice; Misonidazole; Neoplasms; Neoplasms, Experimental; Nerve Tissue; Nitro Compounds; Oxygen; Radiation Dosage; Radiation-Protective Agents; Radiation-Sensitizing Agents; Rats	1983
[Electron acceptor compounds as radiation sensitizers of hypoxic cells in human tumors]. Meditsinskaia radiologiia, 1984, Volume: 29, Issue:9 Topics: Brain Neoplasms; Combined Modality Therapy; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Metronidazole; Misonidazole; Mouth Neoplasms; Neoplasms; Radiation-Sensitizing Agents; Rectal Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms	1984

Trials

5 trial(s) available for metronidazole and misonidazole

Article	Year
Hypoxic cell radiosensitizers. Strahlentherapie. Sonderbande, 1978, Volume: 75 Topics: Animals; Clinical Trials as Topic; Humans; Hyperbaric Oxygenation; Hypoxia; Metronidazole; Mice; Misonidazole; Neoplasms; Radiation-Sensitizing Agents	1978
Hypoxic cell radiosensitizers: expectations and progress in drug development. International journal of radiation oncology, biology, physics, 1985, Volume: 11, Issue:2 Topics: Clinical Trials as Topic; Combined Modality Therapy; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2 Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nimorazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents	1985
Radiosensitizers and protectors. Cancer investigation, 1984, Volume: 2, Issue:4 Topics: Amifostine; Animals; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Humans; Metronidazole; Misonidazole; Neoplasms; Oxygen; Pyrimidines; Radiation-Protective Agents; Radiation-Sensitizing Agents	1984
Radiation and nitroimidazoles in supratentorial high grade gliomas: a second clinical trial. British journal of cancer, 1982, Volume: 46, Issue:1 Topics: Adult; Aged; Cerebellar Neoplasms; Clinical Trials as Topic; Glioblastoma; Humans; Metronidazole; Middle Aged; Misonidazole; Nitroimidazoles; Random Allocation	1982

Other Studies

67 other study(ies) available for metronidazole and misonidazole

Article	Year
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. Journal of medicinal chemistry, 1980, Volume: 23, Issue:6 Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship	1980
TcO(PnA.O-1-(2-nitroimidazole)) [BMS-181321], a new technetium-containing nitroimidazole complex for imaging hypoxia: synthesis, characterization, and xanthine oxidase-catalyzed reduction. Journal of medicinal chemistry, 1994, Jan-07, Volume: 37, Issue:1 Topics: Chromatography, High Pressure Liquid; Crystallization; Crystallography, X-Ray; Dimethylformamide; Electrochemistry; Hypoxia; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Nitroimidazoles; Organotechnetium Compounds; Radionuclide Imaging; Stereoisomerism; Xanthine Oxidase	1994
Hypoxia-selective antitumor agents. 8. Bis(nitroimidazolyl)alkanecarboxamides: a new class of hypoxia-selective cytotoxins and hypoxic cell radiosensitisers. Journal of medicinal chemistry, 1994, Feb-04, Volume: 37, Issue:3 Topics: Aerobiosis; Animals; Antineoplastic Agents; Cell Death; Cell Hypoxia; Cell Line; Chemical Phenomena; Chemistry, Physical; Cricetinae; Cricetulus; DNA Repair; Imidazoles; Mice; Mice, Inbred C3H; Molecular Structure; Neoplasm Transplantation; Radiation-Sensitizing Agents; Structure-Activity Relationship; Tumor Cells, Cultured	1994
Hypoxic-cell sensitisers. Lancet (London, England), 1978, Oct-21, Volume: 2, Issue:8095 Topics: Dose-Response Relationship, Drug; Drug Evaluation; Humans; Hypoxia; Metronidazole; Misonidazole; Neoplasms; Nitroimidazoles	1978
Structure-activity relationships in the development of hypoxic cell radiosensitizers. II. Cytotoxicity and therapeutic ratio. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1979, Volume: 35, Issue:2 Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Metronidazole; Misonidazole; Models, Biological; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Regression Analysis; Structure-Activity Relationship	1979
Evaluation of mutagenicity of metronidazole and mizonidazole on the base of lambda prophage induction and Ames test. Radiobiologia, radiotherapia, 1979, Volume: 20, Issue:5 Topics: Animals; Escherichia coli; Metronidazole; Misonidazole; Mutagens; Nitroimidazoles; Rats; Salmonella typhimurium; Virus Activation	1979
Changes in nerve conduction velocity in the mouse after acute and chronic administration of nitroimidazoles. British journal of cancer, 1979, Volume: 39, Issue:2 Topics: Animals; Cell Survival; Electronics; Female; Metronidazole; Mice; Mice, Inbred CBA; Misonidazole; Neural Conduction; Nitroimidazoles; Sciatic Nerve; Solubility; Temperature	1979
Evaluation of the anticholinesterase activity of metronidazole and misonidazole. European journal of pharmacology, 1979, May-15, Volume: 55, Issue:4 Topics: Animals; Cholinesterase Inhibitors; Diaphragm; Electrophorus; Horses; In Vitro Techniques; Metronidazole; Misonidazole; Nitroimidazoles; Rats	1979
Inhibition of DNA synthesis by nitroheterocycles. I. Correlation with half-wave reduction potential. British journal of cancer, 1979, Volume: 40, Issue:1 Topics: Animals; Depression, Chemical; DNA; Furylfuramide; L Cells; Metronidazole; Mice; Misonidazole; Nitrofurans; Nitroimidazoles; Nitroquinolines; Oxidation-Reduction; Thymidine	1979
Inhibition of DNA synthesis by nitroheterocycles. II. Mechanisms of cytotoxicity. British journal of cancer, 1979, Volume: 40, Issue:1 Topics: Anaerobiosis; Animals; Cell Division; Cell Line; Cell Survival; Depression, Chemical; DNA; DNA, Single-Stranded; Heterocyclic Compounds; L Cells; Metronidazole; Mice; Misonidazole; Nitro Compounds; Nitrofurazone; Thymidine; Time Factors	1979
Development and testing of new hypoxic cell radiosensitizers. Radiology, 1979, Volume: 133, Issue:2 Topics: Animals; Cell Survival; Cricetinae; Dose-Response Relationship, Radiation; Fibroblasts; Lung; Metronidazole; Misonidazole; Neoplasms; Oxygen; Radiation-Sensitizing Agents; Structure-Activity Relationship	1979
Photosensitizers and radiosensitizers in dermatology and oncology. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Sep-22, Volume: 56, Issue:13 Topics: Brain Neoplasms; DNA; Humans; Methoxsalen; Metronidazole; Misonidazole; Mycosis Fungoides; Photochemistry; Photochemotherapy; Psoriasis; Radiation-Sensitizing Agents; Radiotherapy Dosage; Skin Diseases; Skin Neoplasms; Ultraviolet Rays; Ultraviolet Therapy	1979
Comparison of the toxic and radiosensitizing effects of five therapeutic drugs on the mouse jejunum. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1990, Volume: 166, Issue:8 Topics: Animals; Bleomycin; Chlorpromazine; Cisplatin; Cobalt Radioisotopes; Jejunum; Metronidazole; Mice; Misonidazole; Radiation Dosage; Radiation-Sensitizing Agents; Whole-Body Irradiation	1990
Temperature effects on the one-electron reduction potentials of nitroaryl compounds. Free radical research communications, 1991, Volume: 14, Issue:1 Topics: Benzyl Viologen; Free Radicals; Metronidazole; Misonidazole; Molecular Structure; Nitrobenzoates; Nitrofurazone; Oxidation-Reduction; Paraquat; Pulse Radiolysis; Temperature	1991
Toxicity of [PtCl2(NH3)L] in hypoxia; L = misonidazole or metronidazole. Anti-cancer drug design, 1990, Volume: 5, Issue:1 Topics: Aerobiosis; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Hypoxia; Cisplatin; DNA; DNA Restriction Enzymes; Drug Design; Drug Resistance; Leukemia L1210; Metronidazole; Misonidazole; Oxidation-Reduction; Tumor Cells, Cultured	1990
Reduction of 2-, 4- and 5-nitroimidazole drugs by hydrogenase 1 in Clostridium pasteurianum. The Journal of antimicrobial chemotherapy, 1990, Volume: 25, Issue:1 Topics: Clostridium; Ferredoxins; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Hydrogenase; Kinetics; Metronidazole; Misonidazole; Nitroimidazoles; Oxidation-Reduction	1990
Oxic and anoxic photodamage triggered at the subcellular level by the synergistic action of haematoporphyrin derivative and nitroimidazoles. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1986, Volume: 50, Issue:2 Topics: Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Animals; Calcium; Drug Synergism; Hematoporphyrin Derivative; Hematoporphyrins; Metronidazole; Misonidazole; Mitochondria, Liver; Nitroimidazoles; Oxygen Consumption; Radiation-Sensitizing Agents; Rats; Rats, Inbred Strains	1986
Generation of radical anions from metronidazole, misonidazole and azathioprine by photoreduction in the presence of EDTA. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1986, Volume: 50, Issue:5 Topics: Azathioprine; Edetic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Metronidazole; Misonidazole; Oxidation-Reduction; Photochemistry; Polarography	1986
Synthesis and biodistribution of 18F-labeled fluoronitroimidazoles: potential in vivo markers of hypoxic tissue. International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1986, Volume: 37, Issue:7 Topics: Animals; Fluorine; Hypoxia; Metronidazole; Misonidazole; Nitroimidazoles; Radioisotopes; Radionuclide Imaging; Rats; Rats, Inbred Strains; Tissue Distribution	1986
Generation of radical anions of nitrofurantoin, misonidazole, and metronidazole by ascorbate. Archives of biochemistry and biophysics, 1987, Volume: 255, Issue:2 Topics: Anaerobiosis; Anions; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Metronidazole; Misonidazole; Nitrofurantoin; Oxidation-Reduction	1987
[Chemosensitization with nitroimidazole to human gastric cancer transplanted into nude mice]. Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:2 Topics: Animals; Cell Division; DNA Replication; Drug Synergism; Humans; Metronidazole; Mice; Mice, Nude; Misonidazole; Mitomycin; Mitomycins; Neoplasm Transplantation; Stomach Neoplasms	1988
[Enhancement of hyperthermochemotherapy with hypoxic cell radiosensitizers]. Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:3 Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Humans; Hyperthermia, Induced; Metronidazole; Mice; Mice, Nude; Misonidazole; Mitomycin; Mitomycins; Radiation-Sensitizing Agents; Stomach Neoplasms; Transplantation, Heterologous	1988
Enhancement of hyperthermochemotherapy for human gastric cancer in nude mice by thermosensitization with nitroimidazoles. British journal of cancer, 1988, Volume: 58, Issue:1 Topics: Animals; Combined Modality Therapy; DNA, Neoplasm; Hyperthermia, Induced; Metronidazole; Mice; Mice, Nude; Misonidazole; Mitomycins; Stomach Neoplasms	1988
Electrochemical characteristics of nitro-heterocyclic compounds of biological interest. I. The influence of solvent. Free radical research communications, 1988, Volume: 4, Issue:5 Topics: Electrochemistry; Heterocyclic Compounds; Metronidazole; Misonidazole; Nitro Compounds; Ornidazole; Polarography; Solvents	1988
Reduction of nitroheterocyclic drugs by ascorbate and catecholamines: a possible mechanism for the neurotoxicity of nitroheterocyclic drugs. Basic life sciences, 1988, Volume: 49 Topics: Animals; Ascorbic Acid; Biotransformation; Catalase; Catecholamines; Free Radicals; Kinetics; Liver; Male; Metronidazole; Misonidazole; Neurotoxins; Nitrofurantoin; Oxidation-Reduction; Oxygen Consumption; Rats; Superoxide Dismutase	1988
Flash photolysis of misonidazole and metronidazole. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1987, Volume: 51, Issue:1 Topics: Lasers; Metronidazole; Misonidazole; Photolysis	1987
DNA damage induced by reductively activated nitroimidazoles--pH effects. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: DNA, Bacterial; Escherichia coli; Hydrogen-Ion Concentration; Metronidazole; Misonidazole; Nitroimidazoles	1986
Optimization of cancer radiotherapy with selective sensitizers. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1987, Volume: 163, Issue:6 Topics: Cells, Cultured; Chemical Phenomena; Chemistry; Combined Modality Therapy; Humans; Metronidazole; Misonidazole; Neoplasms; Oxygen Consumption; Radiation Dosage; Radiation-Sensitizing Agents; Razoxane	1987
Chloronitroimidazoles as radiosensitizers of hypoxic cells in vitro. Neoplasma, 1987, Volume: 34, Issue:3 Topics: Aerobiosis; Animals; Cell Survival; Chlorine; Glutathione; Hypoxia; Metronidazole; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Structure-Activity Relationship	1987
Distribution of nitroimidazoles and L-phenylalanine mustard in mammary adenocarcinoma 16/C tumors. Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:3 Topics: Adenocarcinoma; Animals; Female; Lissamine Green Dyes; Mammary Neoplasms, Experimental; Melphalan; Metronidazole; Mice; Misonidazole; Nitroimidazoles; Time Factors	1987
Platinum complexes with one radiosensitizing ligand [PtCl2(NH3) (sensitizer)]: radiosensitization and toxicity studies in vitro. Radiation research, 1987, Volume: 112, Issue:2 Topics: Animals; Cisplatin; Cricetinae; In Vitro Techniques; Metronidazole; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Thiazoles	1987
Oxygen depletion in irradiated aqueous solutions containing electron affinic hypoxic cell radiosensitizers. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Acetophenones; Metronidazole; Misonidazole; Nitrofurans; Nitrofurazone; Oxygen; Radiation-Sensitizing Agents; Solutions; Water	1986
Effect of radiation-induced reduction of nitroimidazoles on biologically active DNA. International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7 Topics: Coliphages; DNA, Single-Stranded; DNA, Viral; Metronidazole; Misonidazole; Nitroimidazoles; Ornidazole; Oxidation-Reduction; Radiochemistry	1986
The effect of electron-affinic radiosensitizers on ATP levels in V79 379A Chinese hamster cells. Biochemical pharmacology, 1987, Feb-01, Volume: 36, Issue:3 Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Cell Line; Cricetinae; Cricetulus; Dinitrophenols; Imidazoles; Metronidazole; Misonidazole; Nitrofurantoin; Nitroimidazoles; Radiation-Sensitizing Agents; Sulfhydryl Compounds	1987
Reactions of nitroimidazoles with free radicals--enhancement of reaction by u.v. irradiation. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 47, Issue:5 Topics: Acrylic Resins; Free Radicals; Metronidazole; Misonidazole; Mutagens; Nitroimidazoles; Ornidazole; Potassium; Potassium Compounds; Radiation-Sensitizing Agents; Sulfates; Ultraviolet Rays	1985
Effects of hypoxic cell radiosensitizers on the activity of ATPases. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1981, Volume: 40, Issue:6 Topics: Adenosine Triphosphatases; Animals; Carcinoma, Ehrlich Tumor; Dextran Sulfate; Dextrans; Metronidazole; Mice; Mice, Inbred Strains; Misonidazole; Nitroimidazoles; Oxygen Consumption; Radiation-Sensitizing Agents; Uncoupling Agents	1981
Inhibition of delayed hypersensitivity by metronidazole and misonidazole. International journal of radiation oncology, biology, physics, 1983, Volume: 9, Issue:5 Topics: Animals; Dinitrofluorobenzene; Drug Hypersensitivity; Female; Hypersensitivity, Delayed; Male; Metronidazole; Mice; Mice, Inbred BALB C; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Specific Pathogen-Free Organisms	1983
The oxygen dependence of the reduction of nitroimidazoles in a radiolytic model system. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Acetophenones; Cobalt Radioisotopes; Etanidazole; Gamma Rays; Metronidazole; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Oxygen; Radiation-Sensitizing Agents	1984
Hypoxic cell radiosensitizers in the treatment of malignant brain tumors. Neurosurgery, 1980, Volume: 6, Issue:5 Topics: Animals; Brain Neoplasms; Cricetinae; DNA; Glioblastoma; Humans; Hypoxia; In Vitro Techniques; Metronidazole; Misonidazole; Oxygen Consumption; Radiation-Sensitizing Agents	1980
Influence of anoxic sensitizers on the radiation damage in biologically active DNA in aqueous solution. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1982, Volume: 41, Issue:3 Topics: Acetophenones; Bacteriophage phi X 174; Butanols; Cobalt Radioisotopes; DNA, Single-Stranded; DNA, Viral; Free Radicals; Gamma Rays; Hydroxides; Hydroxyl Radical; Metronidazole; Misonidazole; Nitrofurans; Radiation-Protective Agents; Radiation-Sensitizing Agents	1982
Association of the radiosensitizers metronidazole and misonidazole (RO-07-0582) with bovine serum albumin. Effect of urea and ionic strength. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1984, Volume: 46, Issue:2 Topics: Magnetic Resonance Spectroscopy; Metronidazole; Misonidazole; Nitroimidazoles; Osmolar Concentration; Protein Binding; Radiation-Sensitizing Agents; Serum Albumin, Bovine; Urea	1984
Pulse-radiolysis studies on the interaction of one-electron-reduced species with ascorbate oxidase in aqueous solution. The Biochemical journal, 1983, Jan-01, Volume: 209, Issue:1 Topics: Ascorbate Oxidase; Carbon Dioxide; Free Radicals; Metronidazole; Misonidazole; Models, Chemical; Nitrofurazone; Oxidation-Reduction; Oxidoreductases; Pulse Radiolysis	1983
Response of murine tumours to combinations of CCNU with misonidazole and other radiation sensitizers. British journal of cancer, 1982, Volume: 45, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etanidazole; Female; Leukocyte Count; Lomustine; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Nitrosourea Compounds; Radiation-Sensitizing Agents; Sarcoma, Experimental	1982
Pharmacology and toxicology of sensitizers: mechanism studies. International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8 Topics: Animals; Carcinogens; Humans; Metronidazole; Misonidazole; Mutagens; Nitroimidazoles; Oxidation-Reduction; Radiation-Sensitizing Agents	1984
Radiation-induced reduction of nitroimidazole derivatives in aqueous solution. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1983, Volume: 44, Issue:5 Topics: Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Gamma Rays; Metronidazole; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Radiation-Sensitizing Agents	1983
Lung tumorigenic response of strain A mice exposed to hypoxic cell sensitizers alone and in combination with gamma-radiation. Cancer research, 1983, Volume: 43, Issue:1 Topics: Adenoma; Animals; Hypoxia; Lung; Lung Neoplasms; Metronidazole; Mice; Mice, Inbred A; Misonidazole; Neoplasms, Radiation-Induced; Radiation-Sensitizing Agents	1983
Studies on the action of nitroimidazole drugs. The products of nitroimidazole reduction. Biochemical pharmacology, 1983, Jul-15, Volume: 32, Issue:14 Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Electrolysis; Metronidazole; Misonidazole; Nitrites; Nitroimidazoles; Oxidation-Reduction; Spectrophotometry	1983
Reduction of nitroheterocyclic compounds by mammalian tissues in vivo. Biochemical pharmacology, 1983, Jul-15, Volume: 32, Issue:14 Topics: Acetamides; Animals; Ethanolamine; Ethanolamines; Germ-Free Life; Male; Metronidazole; Misonidazole; Nitrofurazone; Nitroimidazoles; Oxamic Acid; Oxidation-Reduction; Rats; Rats, Inbred Strains	1983
Immunosuppression by hypoxic cell radiosensitizers: a phenomenon of potential clinical importance. International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:6 Topics: Animals; Cell Survival; Graft Rejection; Heart; Heart Transplantation; Immunity, Cellular; Immunosuppression Therapy; Metronidazole; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Rats; Rats, Inbred Strains; Skin Transplantation	1982
Effect of misonidazole or metronidazole pretreatment on the response of the RIF-1 mouse sarcoma to melphalan, cyclophosphamide, chlorambucil and CCNU. British journal of cancer, 1982, Volume: 45, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Survival; Chlorambucil; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Lethal Dose 50; Leukocyte Count; Lomustine; Male; Melphalan; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental	1982
Enhancement of the cytotoxicity of radiosensitizers by modest hyperthermia: the electron-affinity relationship. British journal of cancer, 1982, Volume: 46, Issue:6 Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Hot Temperature; Hydrogen-Ion Concentration; Metronidazole; Misonidazole; Nitrofurantoin; Radiation-Sensitizing Agents; Time Factors	1982
Interaction of the cytotoxic and sensitizing effects of electron-affinic drugs and hyperthermia. National Cancer Institute monograph, 1982, Volume: 61 Topics: Anaerobiosis; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Electron Transport; Hot Temperature; Lung; Metronidazole; Misonidazole; Oxidation-Reduction; Radiation Tolerance; Radiation-Sensitizing Agents	1982
Cytotoxicity of metronidazole (Flagyl) and misonidazole (Ro-07-0582): enhancement by lactate. British journal of cancer, 1981, Volume: 43, Issue:3 Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Drug Synergism; Female; Lactates; Metronidazole; Misonidazole; Nitroimidazoles; Ovary	1981
Role of hypoxic sensitizers in radiotherapy. Indian journal of cancer, 1981, Volume: 18, Issue:1 Topics: Humans; Metronidazole; Misonidazole; Neoplasms; Oxygen; Radiation-Sensitizing Agents	1981
The influence of two radiosensitizers on the induction of chromosome aberrations in human lymphocytes by X-radiation. The British journal of radiology, 1980, Volume: 53, Issue:627 Topics: Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Lymphocytes; Male; Metronidazole; Misonidazole; Nitroimidazoles; Oxygen; X-Rays	1980
Hypoxic-cell sensitizers and sister chromatid exchanges. The British journal of radiology, 1980, Volume: 53, Issue:628 Topics: Crossing Over, Genetic; Humans; Lymphocytes; Male; Metronidazole; Misonidazole; Nitroimidazoles; Sister Chromatid Exchange	1980
Respiratory effects and ascorbate reactions with misonidazole and other recently developed drugs. Cancer clinical trials, 1980,Spring, Volume: 3, Issue:1 Topics: Animals; Cyanides; Dose-Response Relationship, Drug; Kinetics; Metronidazole; Microsomes, Liver; Misonidazole; Nitro Compounds; Nitroimidazoles; Oxygen Consumption; Rats; Sulfhydryl Compounds	1980
Experimental therapy of brain tumors. Progress in clinical and biological research, 1980, Volume: 39 Topics: Animals; Brain Neoplasms; Carmustine; Cell Line; Methods; Metronidazole; Misonidazole; Neoplasms, Experimental; Radiation-Sensitizing Agents; Rats; Sulfhydryl Compounds; Vitamin A	1980
Effect of oxygen-radiosensitizer mixtures on the radiation response of Chinese hamster cells, line V.79-753B, in vitro. I. Survival response. Radiation research, 1980, Volume: 82, Issue:3 Topics: Alkaloids; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cyclic N-Oxides; Dose-Response Relationship, Radiation; Lung; Metronidazole; Misonidazole; Oxygen; Piperidines; Radiation-Sensitizing Agents; Radiotherapy; Spin Labels	1980
Effects of metronidazole and misonidazole on some metabolic parameters of normal tissues in mice. Radiobiologia, radiotherapia, 1980, Volume: 21, Issue:4 Topics: Animals; Body Temperature; Energy Metabolism; Male; Metronidazole; Mice; Misonidazole; Nitroimidazoles; Oxygen Consumption	1980
In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: methotrexate, 5-fluorouracil and adriamycin. British journal of cancer, 1980, Volume: 42, Issue:6 Topics: Animals; Body Weight; Doxorubicin; Drug Therapy, Combination; Fibrosarcoma; Fluorouracil; Leukocyte Count; Male; Mammary Neoplasms, Experimental; Methotrexate; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental	1980
In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: cyclophosphamide and BCNU. British journal of cancer, 1980, Volume: 42, Issue:6 Topics: Animals; Body Weight; Carmustine; Cyclophosphamide; Drug Therapy, Combination; Fibrosarcoma; Leukocyte Count; Male; Mammary Neoplasms, Experimental; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Sarcoma, Experimental	1980
The mechanism of binding of the radiosensitizers metronidazole and misonidazole (Ro-07-0582) to bovine and human serum albumin--a proton NMR study. Radiation research, 1981, Volume: 85, Issue:1 Topics: Animals; Cattle; Humans; Magnetic Resonance Spectroscopy; Metronidazole; Misonidazole; Nitroimidazoles; Protein Binding; Serum Albumin; Serum Albumin, Bovine	1981
Radiation-induced luminescence in DNA: evidence for long-range electron migration. Radiation research, 1994, Volume: 138, Issue:3 Topics: DNA; Electrons; Luminescent Measurements; Metronidazole; Misonidazole; Nitrofurans; Oxidation-Reduction	1994
Noninvasive assessment of tumor hypoxia with 99mTc labeled metronidazole. Pharmaceutical research, 1999, Volume: 16, Issue:5 Topics: Animals; Autoradiography; Cell Hypoxia; Cysteine; Female; Fluorine Radioisotopes; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Metronidazole; Microelectrodes; Misonidazole; Neovascularization, Pathologic; Organotechnetium Compounds; Oxygen; Radiation-Sensitizing Agents; Radionuclide Imaging; Rats; Rats, Inbred F344; Tissue Distribution	1999
Hypoxic cell radiosensitizers: comparative tests of some electron affinic compounds using epidermal cell survival in vivo. Radiation research, 1974, Volume: 60, Issue:1 Topics: Animals; Cell Hypoxia; Dithioerythritol; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Evaluation, Preclinical; Electrons; Epidermal Cells; Epidermis; Female; Lethal Dose 50; Male; Metronidazole; Mice; Misonidazole; Nitrofurans; Nitrogen; Nitroimidazoles; Oxygen; Particle Accelerators; Radiation-Protective Agents; Radiation-Sensitizing Agents; Tiopronin; Wound Healing	1974
Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models. Nuclear medicine communications, 2003, Volume: 24, Issue:5 Topics: Animals; Azides; Carcinoma, Squamous Cell; CHO Cells; Cricetinae; Cricetulus; Fibrosarcoma; Fructose; Glucaric Acid; Hypoxia; Male; Metabolic Clearance Rate; Metronidazole; Mice; Mice, Inbred C3H; Misonidazole; Organotechnetium Compounds; Oxygen; Potassium Cyanide; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution	2003