metronidazole and mercaptopurine

metronidazole has been researched along with mercaptopurine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19907 (21.88)18.7374
1990's6 (18.75)18.2507
2000's9 (28.13)29.6817
2010's10 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Present, DH; Sachar, DB1
Greseth, JL; Perrault, J; Tremaine, WJ1
Cohen, SA; Daum, F; Glassman, M; Holmes, RD; Markowitz, J; Piccoli, D; Rossi, TM; Treem, WR; Ulshen, MH; Winter, HS1
Lloyd-Still, JD1
Riemann, JF1
Greenberger, N1
Korelitz, BI1
Goldstein, F1
Malchow, H1
Gordon, PH; Stein, BL1
van Hogezand, RA1
Buffinton, GD; Doe, WF; McKenzie, SM1
Arseneau, KO; Cohn, SM; Cominelli, F; Connors, AF1
KRETTEK, JE1
Herrlinger, K; Stange, EF1
Boubaker, J; Filali, A; Kallel, L; Karoui, S1
Assulin, Y; Beer-Gabel, M; Chowers, Y; Lahat, A1
Hirata, Y; Joh, T; Kamiya, T; Kataoka, H; Mizoshita, T; Mizushima, T; Murakami, K; Ozeki, K; Shimura, T; Tanida, S; Tsukamoto, H1
Andrews, JM; Bampton, PA; Bell, SJ; Brown, SJ; Connell, WR; De Cruz, P; Debinski, H; Desmond, PV; Elliott, PR; Florin, TH; Gearry, RB; Gibson, PR; Gorelik, A; Hamilton, AL; Johnston, MJ; Kamm, MA; Krejany, EO; Kronborg, I; Lawrance, IC; Leong, RW; Liew, D; Macrae, FA; Prideaux, L; Radford-Smith, G; Ritchie, KJ; Selby, W; Sparrow, M; Woods, R1
Andrews, JM; Bampton, PA; Bell, SJ; Brown, SJ; Connell, WR; De Cruz, P; Debinski, H; Desmond, PV; Elliott, PR; Florin, TH; Gearry, RB; Gibson, PR; Gorelik, A; Hamilton, AL; Jakobovits, S; Johnston, MJ; Kamm, MA; Krejany, EO; Kronborg, I; Lawrance, IC; Leong, RW; Liew, D; Macrae, FA; Prideaux, L; Radford-Smith, G; Ritchie, KJ; Selby, W; Woods, R1

Reviews

7 review(s) available for metronidazole and mercaptopurine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Immunotherapy in inflammatory bowel disease.
    The Medical clinics of North America, 1978, Volume: 62, Issue:1

    Topics: Adult; Alkylating Agents; Antimetabolites; Azathioprine; Child; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cromolyn Sodium; Double-Blind Method; Female; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Metronidazole

1978
Regional enteritis.
    The Alabama journal of medical sciences, 1985, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Azathioprine; Crohn Disease; Diagnosis, Differential; Humans; Intestinal Absorption; Male; Mercaptopurine; Metronidazole; Parenteral Nutrition, Total; Prednisone; Sulfasalazine; Water-Electrolyte Balance

1985
Perianal inflammatory conditions in inflammatory bowel disease.
    Current opinion in general surgery, 1993

    Topics: Abscess; Adult; Colitis, Ulcerative; Combined Modality Therapy; Crohn Disease; Female; Humans; Male; Mercaptopurine; Metronidazole; Proctitis; Rectal Fistula; Rectovaginal Fistula

1993
Medical management of patients with difficult-to-treat inflammatory bowel disease.
    The Netherlands journal of medicine, 1994, Volume: 45, Issue:2

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Humans; Mercaptopurine; Mesalamine; Methotrexate; Metronidazole

1994
[Chronic inflammatory bowel diseases].
    Deutsche medizinische Wochenschrift (1946), 2004, Oct-15, Volume: 129, Issue:42

    Topics: Adrenal Cortex Hormones; Adult; Aminosalicylic Acids; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Azathioprine; Budesonide; Colitis, Ulcerative; Colonoscopy; Controlled Clinical Trials as Topic; Crohn Disease; Diagnosis, Differential; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Magnetic Resonance Imaging; Mercaptopurine; Methotrexate; Metronidazole; Pouchitis; Remission Induction; Tacrolimus; Time Factors; Tomography, X-Ray Computed; Ultrasonography

2004
[Postoperative recurrence in Crohn's disease. Risk factors and methods of prevention].
    La Tunisie medicale, 2006, Volume: 84, Issue:10

    Topics: Algorithms; Anastomosis, Surgical; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Colon; Crohn Disease; Endoscopy; Female; Humans; Ileum; Immunosuppressive Agents; Male; Mercaptopurine; Mesalamine; Metronidazole; Odds Ratio; Randomized Controlled Trials as Topic; Risk; Risk Factors; Secondary Prevention; Smoking; Time Factors

2006

Trials

4 trial(s) available for metronidazole and mercaptopurine

ArticleYear
Immunotherapy in inflammatory bowel disease.
    The Medical clinics of North America, 1978, Volume: 62, Issue:1

    Topics: Adult; Alkylating Agents; Antimetabolites; Azathioprine; Child; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cromolyn Sodium; Double-Blind Method; Female; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Metronidazole

1978
Azathioprine and the treatment of chronic inflammatory bowel disease.
    The Journal of pediatrics, 1990, Volume: 117, Issue:5

    Topics: Adolescent; Adult; Azathioprine; Child; Colitis, Ulcerative; Crohn Disease; Double-Blind Method; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Metronidazole

1990
Crohn's disease management after intestinal resection: a randomised trial.
    Lancet (London, England), 2015, Apr-11, Volume: 385, Issue:9976

    Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Azathioprine; Colonoscopy; Crohn Disease; Female; Humans; Male; Mercaptopurine; Metronidazole; Middle Aged; Recurrence; Treatment Outcome

2015
Efficacy of thiopurines and adalimumab in preventing Crohn's disease recurrence in high-risk patients - a POCER study analysis.
    Alimentary pharmacology & therapeutics, 2015, Volume: 42, Issue:7

    Topics: Adalimumab; Adult; Aged; Azathioprine; Colonoscopy; Crohn Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Mercaptopurine; Metronidazole; Middle Aged; Postoperative Period; Recurrence; Risk Factors; Treatment Outcome; Tumor Necrosis Factor-alpha

2015

Other Studies

22 other study(ies) available for metronidazole and mercaptopurine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
6-mercaptopurine therapy in selected cases of corticosteroid-dependent Crohn's disease.
    Mayo Clinic proceedings, 1991, Volume: 66, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Colonic Diseases; Crohn Disease; Female; Follow-Up Studies; Humans; Intestine, Small; Male; Mercaptopurine; Metronidazole; Middle Aged; Remission Induction; Retrospective Studies; Sulfasalazine; Time Factors

1991
Immunology of inflammatory bowel disease: summary of the proceedings of the Subcommittee on Immunosuppressive Use in IBD.
    Journal of pediatric gastroenterology and nutrition, 1991, Volume: 12, Issue:4

    Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Humans; Immunologic Factors; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lipoxygenase Inhibitors; Mercaptopurine; Mesalamine; Methotrexate; Metronidazole; Steroids

1991
[Therapy of Crohn disease].
    Deutsche medizinische Wochenschrift (1946), 1989, Oct-20, Volume: 114, Issue:42

    Topics: Aminosalicylic Acids; Azathioprine; Colectomy; Crohn Disease; Diet; Glucocorticoids; Humans; Mercaptopurine; Metronidazole; Psychotherapy; Sulfasalazine

1989
Pregnancy, fertility, and inflammatory bowel disease.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:5

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Azathioprine; Colitis, Ulcerative; Crohn Disease; Female; Fetal Diseases; Humans; Infertility, Female; Infertility, Male; Male; Mercaptopurine; Metronidazole; Pregnancy; Pregnancy Complications; Risk; Sulfasalazine

1985
Current status of medical treatment for inflammatory bowel disease.
    The American journal of gastroenterology, 1983, Volume: 78, Issue:12

    Topics: Adrenal Cortex Hormones; Azathioprine; Colitis, Ulcerative; Crohn Disease; Humans; Mercaptopurine; Metronidazole; Parenteral Nutrition, Total; Sulfasalazine

1983
[Therapy of chronic inflammatory bowel diseases].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1983, Volume: 18

    Topics: Acute Disease; Azathioprine; Colitis, Ulcerative; Crohn Disease; Humans; Mercaptopurine; Methylprednisolone; Metronidazole; Parenteral Nutrition; Sulfasalazine

1983
5-aminosalicylic acid prevents oxidant mediated damage of glyceraldehyde-3-phosphate dehydrogenase in colon epithelial cells.
    Gut, 1999, Volume: 44, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Culture Techniques; Colon; Dose-Response Relationship, Drug; Epithelial Cells; Free Radical Scavengers; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hypochlorous Acid; Mercaptopurine; Mesalamine; Methylprednisolone; Metronidazole; Oxidants; Oxidative Stress

1999
Cost-utility of initial medical management for Crohn's disease perianal fistulae.
    Gastroenterology, 2001, Volume: 120, Issue:7

    Topics: Adult; Antibodies, Monoclonal; Crohn Disease; Drug Costs; Drug Therapy, Combination; Female; Gastrointestinal Agents; Health Care Costs; Humans; Infliximab; Male; Mercaptopurine; Metronidazole; Middle Aged; Rectal Fistula

2001
Experience with metronidazole, a new trichomonacide.
    Journal. Iowa State Medical Society, 1962, Volume: 52

    Topics: Female; Humans; Mercaptopurine; Metronidazole; Trichomonas Infections

1962
Endoscopic ultrasound for perianal Crohn's disease: disease and fistula characteristics, and impact on therapy.
    Journal of Crohn's & colitis, 2012, Volume: 6, Issue:3

    Topics: Abscess; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Infective Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Anus Diseases; Azathioprine; Ciprofloxacin; Crohn Disease; Cutaneous Fistula; Endosonography; Female; Humans; Immunosuppressive Agents; Incidental Findings; Infliximab; Male; Mercaptopurine; Mesalamine; Metronidazole; Middle Aged; Rectal Fistula; Retrospective Studies; Tumor Necrosis Factor-alpha; Young Adult

2012
Combination therapy with adalimumab plus intensive granulocyte and monocyte adsorptive apheresis induced clinical remission in a Crohn's disease patient with the loss of response to scheduled adalimumab maintenance therapy: a case report.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:6

    Topics: Adalimumab; Antibodies, Monoclonal, Humanized; Colonoscopy; Combined Modality Therapy; Crohn Disease; Granulocytes; Humans; Immunosuppressive Agents; Leukapheresis; Leukocyte Reduction Procedures; Male; Mercaptopurine; Mesalamine; Metronidazole; Monocytes; Parenteral Nutrition, Total; Prednisolone; Remission Induction; Young Adult

2012