metronidazole and fidaxomicin

metronidazole has been researched along with fidaxomicin in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (5.80)	29.6817
2010's	49 (71.01)	24.3611
2020's	16 (23.19)	2.80

Authors

Authors	Studies
Galang, MA; Gerding, DN; Hecht, DW; Johnson, S; Osmolski, JR; Sambol, SP	1
Karlowsky, JA; Laing, NM; Zhanel, GG	1
Donskey, C; Goldstein, EJ; Louie, T; Miller, M; Mullane, K	1
Bremner, JB; Casadei, G; Chen, C; Doll, NK; Kelso, MJ; Lewis, K	1
Chang, M; De Benedetti, S; Fisher, JF; Janardhanan, J; Lastochkin, E; Masitas, C; Mobashery, S; Oliver, AG; Qian, Y; Schroeder, VA; Speri, E; Wang, M; Wolter, WR	1
Kapoor, S	1
Gerding, DN; Johnson, S	1
Dolgin, E	1
Vaishnavi, C	1
Bliss, D; Butler, M; Drekonja, DM; Filice, GA; MacDonald, R; Rector, TS; Wilt, TJ	1
Kee, VR	1
Gerding, DN; Gorbach, SL; Johnson, S; Louie, TJ; Ruiz, NM	1
Cornely, OA; Crook, DW; Gorbach, SL; Louie, TJ; Miller, MA	1
Babakhani, F; Bouillaut, L; Gomez, A; Nguyen, L; Sears, P; Sonenshein, AL	1
Guerrant, RL; Hoffman, PS; Kolling, GL; Li, Y; Moore, JH; Riggins, MS; van Opstal, EJ; Warren, CA	1
Babakhani, F; Bouillaut, L; Gomez, A; Sears, P; Sims, C; Sonenshein, AL	1
Arzese, A; Bassetti, M; Pecori, D; Villa, G; Wilcox, M	1
Bauer, MP; Debast, SB; Kuijper, EJ; Sanders, IM; Wilcox, MH	1
Dupont, HL	2
Neurath, MF; Strauss, R	1
Baji, P; Banai, J; Brodszky, V; Gulácsi, L; Kertész, A; Kopcsóné Németh, I; Ludwig, E; Péntek, M; Prinz, G; Reményi, P; Strbák, B; Zsoldiné Urbán, E	1
Clutter, DS; Dubrovskaya, Y; Merl, MY; Press, R; Safdar, A; Teperman, L	1
Ebigbo, A; Messmann, H	1
John, E; Lippmann, N; Lübbert, C; Mössner, J; Weis, S	1
Citron, DM; Goldstein, EJ; Tyrrell, KL	1
Curry, SR; Marsh, JW	1
Miigoć, H; Piekarska, M; Wandałowicz, AD	1
Chen, X; Cheng, M; Hing, TC; Ho, S; Ichikawa, Y; Kelly, CP; Koon, HW; Pothoulakis, C	1
Cornely, OA; Ivanescu, C; Nathwani, D; Odeyemi, IA; Odufowora-Sita, O; Retsa, P	1
Belyaev, O; Chromik, AM; Deleites, C; Herzog, T; Uhl, W	1
Leeds, JA; Sachdeva, M	1
Johnson, S; Soriano, MM	1
Keller, JJ; Kuijper, EJ	1
Biswas, JS; Goldenberg, SD; Newsholme, W; Otter, JA; Patel, A; van Kleef, E; Wade, P	1
Alm, E; Burgess, J; Burns, L; Didyk, E; Edelstein, C; Giovanelli, A; Kassam, Z; Mendolia, G; Noh, A; Smith, M; Stollman, N	1
Marra, F; Ng, K	1
Doron, S; Gorbach, S; Mizusawa, M	1
Forbes, BA; Gerding, DN; Goldstein, EJ; Jacobus, NV; Jenkins, SG; Johnson, S; McDermott, LA; Mirrett, S; Patel, R; Snydman, DR; Stone, S; Thorpe, C	1
Clozel, M; Enderlin-Paput, M; Locher, HH; Pfaff, P; Ritz, D; Seiler, P; Weiss, M	1
Freeman, J; Vernon, J; Vickers, R; Wilcox, MH	1
Alam, MJ; Bassères, E; Chang, L; Endres, BT; Garey, KW; Kakadiaris, IA; Memariani, A; Vickers, RJ	1
Beneš, J; Polívková, S	1
Stallmach, A	1
Evans, CT; Nelson, RL; Suda, KJ	1
Bachmann, O; Dersch, P; Solbach, P	1
Cheng, JW; Kong, F; Kudinha, T; Liao, JW; Xiao, M; Xu, YC; Yang, QW; Yu, SY; Zhou, ML	1
Burton, HE; Mitchell, SA; Watt, M	1
Boegli, L; Chesnel, L; deLancey Pulcini, E; Fisher, S; James, GA; Stewart, PS	1
Dorr, MB; Dubberke, ER; Ellison, MC; Eves, K; Gerding, DN; Guris, D; Hanson, ME; Kao, D; Kelly, CP; Kumar, PN; Lee, C; Rahav, G; Yacyshyn, B	1
Mullish, BH; Williams, HR	1
Boulos, RA; Pagano, P; Pillar, CM; Shinabarger, DL; Wolfe, C	1
Fernández Lisón, LC; Malpartida Flores, M; Martín Rizo, L	1
Ramesh, MS; Yee, J	1
English, M; Fukushima, A; Okumura, H; Shoji, S; Taieb, V	1
English, M; Okumura, H; Shoji, S; Ueyama, M	1
Boggiano, VL; Smith, KL; Sullivan, MH	1
Bickett-Burkhart, K; Chalasani, N; Fischer, M; Gandhi, D; Orman, ES; Phatharacharukul, P; Purpura, RD; Xu, H	1
Benes, J; Capek, V; Krutova, M; Polivkova, S; Sykorova, B	1
Campbell, DL; Gentry, CA; Williams, RJ	1
Addison, B; Addison, RM; Anderson, DJ; Gergen-Teague, MF; Rutala, WA; Sexton, DJ; Turner, NA; Warren, BG; Weber, DJ	1
Alangaden, GJ; Church, B; Davis, SL; Kenney, RM; Wu, T	1
Collins, DA; Riley, TV	1
Dai, J; Gong, J; Guo, R	1
Krutova, M; Kuijper, E; Wilcox, M	1
Chuard, C; Meuwly, M	1
Bishop, EJ; Tiruvoipati, R	1
Obata, K; Yamashita, S	1
Álvarez-Pérez, S; Anega, B; Blanco, JL; García, ME; Hernández, M	1

Reviews

24 review(s) available for metronidazole and fidaxomicin

Article	Year
Management of Clostridium difficile infection: thinking inside and outside the box. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, Dec-01, Volume: 51, Issue:11 Topics: Aminoglycosides; Anti-Bacterial Agents; Antibodies, Bacterial; Antibodies, Monoclonal; Antitoxins; Clostridioides difficile; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Metronidazole; Vaccination; Vancomycin	2010
Clostridium difficile infection: clinical spectrum and approach to management. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2011, Volume: 30, Issue:6 Topics: Aminoglycosides; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Dietary Supplements; Digestive System Surgical Procedures; Disease Management; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Routes; Fidaxomicin; Humans; Ileus; Immunoglobulins, Intravenous; Inflammatory Bowel Diseases; Metronidazole; Severity of Illness Index; Vancomycin; Withholding Treatment	2011
Comparative effectiveness of Clostridium difficile treatments: a systematic review. Annals of internal medicine, 2011, Dec-20, Volume: 155, Issue:12 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Comparative Effectiveness Research; Diarrhea; Drug Therapy, Combination; Fidaxomicin; Humans; Metronidazole; Recurrence; Vancomycin	2011
Clostridium difficile infection in older adults: a review and update on its management. The American journal of geriatric pharmacotherapy, 2012, Volume: 10, Issue:1 Topics: Aged; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Diarrhea; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Infection Control; Metronidazole; Risk Factors; Vancomycin	2012
Epidemiology, diagnosis and treatment of Clostridium difficile infection. Expert review of anti-infective therapy, 2012, Volume: 10, Issue:12 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Metronidazole; Risk Factors; Secondary Prevention; Severity of Illness Index; Treatment Outcome; Vancomycin	2012
Diagnosis and management of Clostridium difficile infection. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2013, Volume: 11, Issue:10 Topics: Administration, Oral; Aminoglycosides; Anti-Infective Agents; Biological Therapy; Clostridioides difficile; Clostridium Infections; Colectomy; False Positive Reactions; Fidaxomicin; Humans; Immunotherapy; Metronidazole; Molecular Diagnostic Techniques; Vancomycin	2013
[Antimicrobial therapy of Clostridium difficile infection. Systematic review and meta-analysis of the scientific evidence]. Orvosi hetilap, 2013, Jun-09, Volume: 154, Issue:23 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Metronidazole; Treatment Outcome; Vancomycin	2013
[Clostridium difficile infecion--diagnostics, prevention and treatment]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2014, Volume: 36, Issue:214 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Diarrhea; Feces; Fidaxomicin; Humans; Metronidazole; Probiotics; Secondary Prevention; Vancomycin	2014
Challenges and opportunities in the management of Clostridium difficile infection. Expert review of gastroenterology & hepatology, 2014, Volume: 8, Issue:8 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Fidaxomicin; Humans; Immunologic Factors; Metronidazole; Probiotics; Vancomycin	2014
Clinical efficacy of fidaxomicin compared with vancomycin and metronidazole in Clostridium difficile infections: a meta-analysis and indirect treatment comparison. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:11 Topics: Aminoglycosides; Anti-Bacterial Agents; Clinical Trials, Phase III as Topic; Clostridioides difficile; Clostridium Infections; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Metronidazole; Treatment Outcome; Vancomycin	2014
Treatment of Clostridium difficile infections. Infectious disease clinics of North America, 2015, Volume: 29, Issue:1 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Drug Administration Schedule; Drug Therapy, Combination; Fidaxomicin; Gastrointestinal Diseases; Humans; Metronidazole; Nitro Compounds; Randomized Controlled Trials as Topic; Recurrence; Rifamycins; Rifaximin; Thiazoles; Vancomycin	2015
Treatment of recurrent and severe Clostridium difficile infection. Annual review of medicine, 2015, Volume: 66 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Feces; Fidaxomicin; Humans; Metronidazole; Microbiota; Recurrence; Severity of Illness Index; Transplantation; Vancomycin	2015
Controversies Around Epidemiology, Diagnosis and Treatment of Clostridium difficile Infection. Drugs, 2015, Volume: 75, Issue:10 Topics: Aminoglycosides; Anti-Bacterial Agents; Enterocolitis, Pseudomembranous; Fecal Microbiota Transplantation; Fidaxomicin; Humans; Incidence; Metronidazole; Molecular Diagnostic Techniques; Polymerase Chain Reaction; Probiotics; Recurrence; Risk Factors; Vancomycin	2015
Clostridium difficile Diarrhea in the Elderly: Current Issues and Management Options. Drugs & aging, 2015, Volume: 32, Issue:8 Topics: Aged; Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Diarrhea; Fidaxomicin; Humans; Metronidazole; Recurrence; Risk Factors; Vancomycin	2015
Antibiotic treatment for Clostridium difficile-associated diarrhoea in adults. The Cochrane database of systematic reviews, 2017, 03-03, Volume: 3 Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Bacitracin; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Metronidazole; Randomized Controlled Trials as Topic; Teicoplanin; Treatment Outcome; Vancomycin	2017
[Individualized treatment strategies for Clostridium difficile infections]. Der Internist, 2017, Volume: 58, Issue:7 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Fecal Microbiota Transplantation; Female; Fidaxomicin; Humans; Metronidazole; Recurrence; Secondary Prevention; Vancomycin	2017
A Systematic Literature Review of Economic Evaluations of Antibiotic Treatments for Clostridium difficile Infection. PharmacoEconomics, 2017, Volume: 35, Issue:11 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridium Infections; Cost-Benefit Analysis; Drug Costs; Fidaxomicin; Hospitalization; Humans; Metronidazole; Recurrence; Vancomycin	2017
Clinical medicine (London, England), 2018, Volume: 18, Issue:3 Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Diarrhea; Enterocolitis, Pseudomembranous; Fecal Microbiota Transplantation; Fidaxomicin; Humans; Metronidazole; Probiotics; Vancomycin	2018
Clostridioides difficile Infection in Chronic Kidney Disease/End-Stage Renal Disease. Advances in chronic kidney disease, 2019, Volume: 26, Issue:1 Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Antimicrobial Stewardship; Broadly Neutralizing Antibodies; Clostridium Infections; Enterocolitis, Pseudomembranous; Fecal Microbiota Transplantation; Fidaxomicin; Hand Hygiene; Health Care Costs; Humans; Infection Control; Kidney Failure, Chronic; Length of Stay; Metronidazole; Patient Isolation; Renal Insufficiency, Chronic; Secondary Prevention; Vancomycin	2019
Fidaxomicin compared with vancomycin and metronidazole for the treatment of Clostridioides (Clostridium) difficile infection: A network meta-analysis. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2020, Volume: 26, Issue:1 Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Fidaxomicin; Humans; Metronidazole; Recurrence; Treatment Outcome; Vancomycin	2020
Ridinilazole: a novel, narrow-spectrum antimicrobial agent targeting Clostridium (Clostridioides) difficile. Letters in applied microbiology, 2022, Volume: 75, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Benzimidazoles; Clostridioides; Clostridioides difficile; Clostridium; Clostridium Infections; Fidaxomicin; Humans; Metronidazole; Pyridines; Vancomycin	2022
Real-world comparison of fidaxomicin versus vancomycin or metronidazole in the treatment of Clostridium difficile infection: a systematic review and meta-analysis. European journal of clinical pharmacology, 2022, Volume: 78, Issue:11 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridium Infections; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Metronidazole; Vancomycin	2022
Clostridioides difficile infection: are the three currently used antibiotic treatment options equal from pharmacological and microbiological points of view? International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022, Volume: 124 Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Fidaxomicin; Humans; Metronidazole	2022
Management of Clostridioides difficile infection in adults and challenges in clinical practice: review and comparison of current IDSA/SHEA, ESCMID and ASID guidelines. The Journal of antimicrobial chemotherapy, 2022, 12-23, Volume: 78, Issue:1 Topics: Adult; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Fidaxomicin; Humans; Metronidazole; Vancomycin	2022

Trials

6 trial(s) available for metronidazole and fidaxomicin

Article	Year
Clinical outcomes, safety, and pharmacokinetics of OPT-80 in a phase 2 trial with patients with Clostridium difficile infection. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glycosides; Humans; Male; Middle Aged; Treatment Outcome	2009
Treatment of first recurrence of Clostridium difficile infection: fidaxomicin versus vancomycin. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Volume: 55 Suppl 2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Canada; Clostridioides difficile; Clostridium Infections; Confidence Intervals; Double-Blind Method; Europe; Feces; Female; Fidaxomicin; Humans; Kaplan-Meier Estimate; Male; Metronidazole; Middle Aged; Secondary Prevention; Time Factors; Treatment Outcome; United States; Vancomycin; Young Adult	2012
[Challenges of Clostridium difficile infection]. Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2013, Volume: 108, Issue:8 Topics: Aminoglycosides; Biodiversity; Cause of Death; Colonoscopy; Cross Infection; Disinfection; Enterocolitis, Pseudomembranous; Feces; Fidaxomicin; Hospital Mortality; Humans; Metronidazole; Patient Readmission; Prognosis; Recurrence; Tomography, X-Ray Computed; Transplantation; Vancomycin	2013
Reduction in Clostridium difficile environmental contamination by hospitalized patients treated with fidaxomicin. The Journal of hospital infection, 2015, Volume: 90, Issue:3 Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; Environmental Microbiology; Female; Fidaxomicin; Hospitalization; Humans; Male; Metronidazole; Vancomycin	2015
Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection in Patients at Increased Risk for Recurrence. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 08-16, Volume: 67, Issue:5 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Neutralizing; Broadly Neutralizing Antibodies; Clostridioides difficile; Clostridium Infections; Fecal Microbiota Transplantation; Female; Fidaxomicin; Humans; Male; Metronidazole; Middle Aged; Patient Readmission; Recurrence; Risk Factors; Secondary Prevention; Vancomycin; Young Adult	2018
Impact of Oral Metronidazole, Vancomycin, and Fidaxomicin on Host Shedding and Environmental Contamination With Clostridioides difficile. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 03-01, Volume: 74, Issue:4 Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Clostridioides; Clostridioides difficile; Clostridium Infections; Fidaxomicin; Humans; Metronidazole; Prospective Studies; Vancomycin	2022

Other Studies

39 other study(ies) available for metronidazole and fidaxomicin

Article	Year
In vitro activities of 15 antimicrobial agents against 110 toxigenic clostridium difficile clinical isolates collected from 1983 to 2004. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8 Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous; Humans; Microbial Sensitivity Tests; United States	2007
In vitro activity of OPT-80 tested against clinical isolates of toxin-producing Clostridium difficile. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11 Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; Glycosides; Humans; In Vitro Techniques; Microbial Sensitivity Tests	2008
Diarylacylhydrazones: Clostridium-selective antibacterials with activity against stationary-phase cells. Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2 Topics: Aminoglycosides; Anti-Bacterial Agents; Cell Cycle; Cell Line; Clostridioides difficile; Fidaxomicin; Humans; Hydrazones; Microbial Sensitivity Tests	2014
Structure-Activity Relationship for the Picolinamide Antibacterials that Selectively Target ACS medicinal chemistry letters, 2021, Jun-10, Volume: 12, Issue:6 Topics:	2021
Treatment of Clostridium difficile disease in patients not responding to metronidazole. The Journal of infection, 2008, Volume: 56, Issue:5 Topics: Aminoglycosides; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Diarrhea; Drug Resistance, Bacterial; Fidaxomicin; Humans; Immunoglobulins, Intravenous; Metronidazole; Polymers; Sulfonic Acids; Treatment Failure; Treatment Outcome	2008
'Game changer' antibiotic and others in works for superbug. Nature medicine, 2011, Volume: 17, Issue:1 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Clostridioides difficile; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Metronidazole; Secondary Prevention; Streptococcal Infections; United States; United States Food and Drug Administration; Vancomycin	2011
Sustained clinical response as an endpoint in treatment trials of Clostridium difficile-associated diarrhea. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:8 Topics: Aminoglycosides; Anti-Bacterial Agents; Clinical Trials, Phase III as Topic; Clostridioides difficile; Diarrhea; Endpoint Determination; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Metronidazole; Polymers; Sulfonic Acids; Treatment Outcome; Vancomycin	2012
Fidaxomicin inhibits spore production in Clostridium difficile. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Volume: 55 Suppl 2 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Load; Clostridioides difficile; Clostridium Infections; Fidaxomicin; Gene Expression Regulation, Bacterial; Genes, Bacterial; Metronidazole; Microbial Sensitivity Tests; Rifamycins; Rifaximin; Spores, Bacterial; Vancomycin	2012
Vancomycin treatment's association with delayed intestinal tissue injury, clostridial overgrowth, and recurrence of Clostridium difficile infection in mice. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteroides; Cecum; Clostridioides difficile; Clostridium Infections; DNA, Bacterial; Enterocolitis, Pseudomembranous; Feces; Fidaxomicin; Intestines; Male; Metronidazole; Mice; Mice, Inbred C57BL; Nitro Compounds; Recurrence; Thiazoles; Treatment Outcome; Vancomycin	2013
Fidaxomicin inhibits toxin production in Clostridium difficile. The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:3 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Culture Media; Enterotoxins; Enzyme-Linked Immunosorbent Assay; Fidaxomicin; Gene Expression; Gene Expression Profiling; Humans; Metronidazole; Vancomycin	2013
Antimicrobial activity of LFF571 and three treatment agents against Clostridium difficile isolates collected for a pan-European survey in 2008: clinical and therapeutic implications. The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:6 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Enterocolitis, Pseudomembranous; Europe; Fidaxomicin; Humans; Metronidazole; Microbial Sensitivity Tests; Multilocus Sequence Typing; Polymerase Chain Reaction; Ribotyping; Thiazoles; Treatment Outcome; Vancomycin	2013
[Clostridium difficile infections - still a major challenge]. MMW Fortschritte der Medizin, 2013, Apr-18, Volume: 155, Issue:7 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Colectomy; Combined Modality Therapy; Cross Infection; Disease Notification; Enterocolitis, Pseudomembranous; Fidaxomicin; Metronidazole; Probiotics; Vancomycin; Virulence	2013
Fidaxomicin versus conventional antimicrobial therapy in 59 recipients of solid organ and hematopoietic stem cell transplantation with Clostridium difficile-associated diarrhea. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:9 Topics: Adult; Aged; Aminoglycosides; Analysis of Variance; Anti-Bacterial Agents; Clinical Trials as Topic; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Female; Fidaxomicin; Hematopoietic Stem Cell Transplantation; Humans; Male; Metronidazole; Middle Aged; Organ Transplantation; Survival Analysis; Treatment Outcome; Vancomycin; Vancomycin Resistance	2013
[Clostridium difficile infection (CDI) in the course of time - an issue only for the internist?]. Zentralblatt fur Chirurgie, 2014, Volume: 139, Issue:4 Topics: Aminoglycosides; Clostridioides difficile; Colectomy; Colostomy; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Enterocolitis, Pseudomembranous; Feces; Fidaxomicin; Germany; Humans; Incidence; Metronidazole; Recurrence; Transplantation; Vancomycin	2014
Comparative in vitro activities of SMT19969, a new antimicrobial agent, against 162 strains from 35 less frequently recovered intestinal Clostridium species: implications for Clostridium difficile recurrence. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium; Cluster Analysis; Fidaxomicin; Metronidazole; Microbial Sensitivity Tests; RNA, Ribosomal, 16S; Species Specificity; Vancomycin	2014
Therapeutic approaches for Clostridium difficile infections. Current protocols in microbiology, 2013, Oct-02, Volume: 30 Topics: Aminoglycosides; Anti-Infective Agents; Antibodies, Bacterial; Antibodies, Monoclonal; Antitoxins; Bacterial Vaccines; Biological Therapy; Clostridioides difficile; Clostridium Infections; Diarrhea; Drug Therapy; Fidaxomicin; Humans; Immunotherapy; Metronidazole; Vancomycin	2013
Fidaxomicin inhibits Clostridium difficile toxin A-mediated enteritis in the mouse ileum. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacterial Toxins; Clostridioides difficile; Edema; Enterocolitis, Pseudomembranous; Enterotoxins; Epithelial Cells; Fibroblasts; Fidaxomicin; Gene Expression; Ileum; Injections, Intralesional; Interleukin-1beta; Intestinal Mucosa; Male; Metronidazole; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; RNA, Messenger; Vancomycin	2014
[Clostridium difficile in visceral surgery]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2015, Volume: 86, Issue:8 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Cohort Studies; Cross Infection; Cross-Sectional Studies; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Female; Fidaxomicin; Germany; Hospital Mortality; Humans; Incidence; Intensive Care Units; Male; Metronidazole; Middle Aged; Minocycline; Patient Readmission; Retrospective Studies; Survival Rate; Tigecycline; Vancomycin; Young Adult	2015
Subinhibitory concentrations of LFF571 reduce toxin production by Clostridium difficile. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:2 Topics: Aminoglycosides; Clostridioides difficile; Fidaxomicin; Metronidazole; Microbial Sensitivity Tests; Thiazoles; Vancomycin	2015
Frozen encapsulated stool in recurrent Clostridium difficile: exploring the role of pills in the treatment hierarchy of fecal microbiota transplant nonresponders. The American journal of gastroenterology, 2015, Volume: 110, Issue:4 Topics: Abdominal Pain; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Biological Therapy; Capsules; Clostridioides difficile; Colonoscopy; Diarrhea; Drug Administration Schedule; Enterocolitis, Pseudomembranous; Feces; Female; Fidaxomicin; Freezing; Humans; Irritable Bowel Syndrome; Male; Metronidazole; Microbiota; Recurrence; Transplantation, Homologous; Treatment Outcome; Vancomycin	2015
U.S.-Based National Sentinel Surveillance Study for the Epidemiology of Clostridium difficile-Associated Diarrheal Isolates and Their Susceptibility to Fidaxomicin. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Toxins; Clindamycin; Clostridioides difficile; Diarrhea; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous; Fidaxomicin; Fluoroquinolones; Genes, Bacterial; Humans; Metronidazole; Microbial Sensitivity Tests; Moxifloxacin; Multiplex Polymerase Chain Reaction; Prohibitins; Sentinel Surveillance; United States; Vancomycin	2015
Cadazolid Does Not Promote Intestinal Colonization of Vancomycin-Resistant Enterococci in Mice. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Clostridioides difficile; Colony Count, Microbial; Diarrhea; Enterocolitis, Pseudomembranous; Fidaxomicin; Intestines; Metronidazole; Mice; Microbial Sensitivity Tests; Oxazolidinones; Streptococcal Infections; Treatment Outcome; Vancomycin; Vancomycin Resistance; Vancomycin-Resistant Enterococci	2016
Susceptibility of Clostridium difficile Isolates of Varying Antimicrobial Resistance Phenotypes to SMT19969 and 11 Comparators. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1 Topics: Aminoglycosides; Anti-Bacterial Agents; Benzimidazoles; Ceftriaxone; Clostridioides difficile; Clostridium Infections; Drug Resistance, Multiple, Bacterial; Fidaxomicin; Fluoroquinolones; Humans; Linezolid; Metronidazole; Microbial Sensitivity Tests; Moxifloxacin; Phenotype; Pyridines; Ribotyping; Vancomycin	2016
A novel method for imaging the pharmacological effects of antibiotic treatment on Clostridium difficile. Anaerobe, 2016, Volume: 40 Topics: Agar; Aminoglycosides; Anti-Bacterial Agents; Cell Wall; Clostridioides difficile; Culture Media; Fidaxomicin; Metronidazole; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Optical Imaging; Vancomycin	2016
[Antibiotic treatment of clostridial colitis]. Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne, 2016,Winter, Volume: 65, Issue:1 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Metronidazole; Recurrence; Vancomycin	2016
[Clostridium difficile infection : What is currently available for treatment?] Der Internist, 2016, Volume: 57, Issue:12 Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Diarrhea; Enterocolitis, Pseudomembranous; Evidence-Based Medicine; Fidaxomicin; Humans; Megacolon, Toxic; Metronidazole; Treatment Outcome; Vancomycin	2016
High in vitro activity of fidaxomicin against Clostridium difficile isolates from a university teaching hospital in China. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2018, Volume: 51, Issue:3 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Toxins; China; Clostridioides difficile; Clostridium Infections; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Fidaxomicin; Fluoroquinolones; Genes, Bacterial; Hospitals, Teaching; Hospitals, University; Humans; Metronidazole; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Multilocus Sequence Typing; Ribotyping; Tigecycline; Vancomycin	2018
Analysis of Clostridium difficile biofilms: imaging and antimicrobial treatment. The Journal of antimicrobial chemotherapy, 2018, Jan-01, Volume: 73, Issue:1 Topics: Aminoglycosides; Anti-Bacterial Agents; Biofilms; Biological Transport; Clostridioides difficile; Colony Count, Microbial; Fidaxomicin; Humans; Lipopeptides; Metronidazole; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Peptides, Cyclic; Spores, Bacterial; Vancomycin	2018
Comparison of the in vitro antibacterial activity of Ramizol, fidaxomicin, vancomycin, and metronidazole against 100 clinical isolates of Clostridium difficile by broth microdilution. Diagnostic microbiology and infectious disease, 2018, Volume: 92, Issue:3 Topics: Anti-Bacterial Agents; Benzoates; Clostridioides difficile; Drug Resistance, Bacterial; Enterocolitis, Pseudomembranous; Fidaxomicin; Humans; Inhibitory Concentration 50; Metronidazole; Microbial Sensitivity Tests; Stilbenes; Vancomycin	2018
Fidaxomicin in the treatment of Clostridium difficile infection in oncohematology patients. Medicina clinica, 2019, 10-11, Volume: 153, Issue:7 Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Colonic Neoplasms; Diarrhea; Female; Fidaxomicin; Hematologic Neoplasms; Humans; Male; Metronidazole; Middle Aged; Treatment Outcome; Vancomycin	2019
Cost-effectiveness analysis of fidaxomicin for the treatment of Clostridioides (Clostridium) difficile infection in Japan. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2020, Volume: 26, Issue:6 Topics: Aged; Anti-Bacterial Agents; Clinical Trials, Phase III as Topic; Clostridioides difficile; Clostridium Infections; Cost-Benefit Analysis; Drug Costs; Drug Utilization Review; Female; Fidaxomicin; Humans; Japan; Length of Stay; Male; Metronidazole; Middle Aged; Network Meta-Analysis; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Recurrence; Vancomycin	2020
Management of difficult-to-treat BMJ case reports, 2020, Mar-29, Volume: 13, Issue:3 Topics: Administration, Intravenous; Anti-Bacterial Agents; Clostridium Infections; Colitis; Combined Modality Therapy; Drug Resistance, Multiple, Bacterial; Fecal Microbiota Transplantation; Fidaxomicin; Foot; Humans; Male; Metronidazole; Middle Aged; Osteomyelitis; Vancomycin	2020
Incidence and Risk Factors of Recurrent Clostridioides difficile Infection in Patients With Cirrhosis. Clinical and translational gastroenterology, 2020, Volume: 11, Issue:7 Topics: Aged; Anti-Bacterial Agents; Clostridioides; Clostridium Infections; Comorbidity; Diagnostic Errors; Female; Fidaxomicin; Humans; Incidence; Lactulose; Laxatives; Liver Cirrhosis; Male; Metronidazole; Middle Aged; Patient Readmission; Recurrence; Retrospective Studies; Risk Factors; Severity of Illness Index; Treatment Failure; Vancomycin	2020
Fidaxomicin versus metronidazole, vancomycin and their combination for initial episode, first recurrence and severe Clostridioides difficile infection - An observational cohort study. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021, Volume: 103 Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cohort Studies; Female; Fidaxomicin; Hospitalization; Humans; Logistic Models; Male; Metronidazole; Middle Aged; Recurrence; Treatment Outcome; Vancomycin	2021
Outcomes associated with recent guideline recommendations removing metronidazole for treatment of non-severe Clostridioides difficile infection: a retrospective, observational, nationwide cohort study. International journal of antimicrobial agents, 2021, Volume: 57, Issue:3 Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Drug Utilization; Female; Fidaxomicin; Humans; Male; Metronidazole; Middle Aged; Practice Guidelines as Topic; Recurrence; Retrospective Studies; Risk Factors; Treatment Outcome; Vancomycin	2021
Outcomes of clinical decision support for outpatient management of Infection control and hospital epidemiology, 2022, Volume: 43, Issue:10 Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Decision Support Systems, Clinical; Female; Fidaxomicin; Humans; Male; Metronidazole; Middle Aged; Outpatients; Vancomycin	2022
[Clostridioides difficile infection: various therapeutic approaches]. Revue medicale suisse, 2022, Oct-12, Volume: 18, Issue:799 Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Fidaxomicin; Humans; Metronidazole; Vancomycin	2022
[A case of recurrent Clostridium difficile infection with type 2 diabetes mellitus indicating the usefulness of metformin hydrochloride]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2023, Volume: 120, Issue:2 Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Diabetes Mellitus, Type 2; Female; Fidaxomicin; Humans; Metformin; Metronidazole	2023
In vitro activity of fidaxomicin and combinations of fidaxomicin with other antibiotics against Clostridium perfringens strains isolated from dogs and cats. BMC veterinary research, 2023, Nov-16, Volume: 19, Issue:1 Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Clindamycin; Clostridioides difficile; Clostridium Infections; Clostridium perfringens; Diarrhea; Dog Diseases; Dogs; Erythromycin; Fidaxomicin; Humans; Imipenem; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Vancomycin	2023