metronidazole and chitosan

metronidazole has been researched along with chitosan in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.00)18.2507
2000's7 (17.50)29.6817
2010's22 (55.00)24.3611
2020's9 (22.50)2.80

Authors

AuthorsStudies
Amiji, MM; Patel, VR1
Amiji, M; Patel, V; Qaqish, R; Shah, S1
Kawashima, S; Miyamoto, E; Murata, Y; Sasaki, N1
Al Gamal, S; El-Kamel, A; Naggar, V; Sokar, M1
Akncbay, H; Ay, ZY; Senel, S1
Alsarra, IA; Ashri, LY; El-Kamel, AH1
Anupurba, S; Barat, R; Mittal, N; Pandit, JK; Srinatha, A1
Ambrogi, V; Pagano, C; Perioli, L; Rossi, C; Scuota, S1
De Lima, MS; Fonseca, JL; Freire, MS; Pereira, MR1
Al Remawi, MM; Al Shami, MR; Arafat, TA; Badwan, AA; Eftaiha, AF; Qinna, N; Rashid, IS1
Maharramov, A; Ramazanov, MA; Saboktakin, MR; Tabatabaie, RM1
Chaud, MV; Evangelista, RC; Ferrari, PC; Ferraz, HG; Giorgetti, L; Oliveira, GF; Souza, FM1
Boonme, P; Pichayakorn, W1
Kostova, B; Momekova, D; Petrov, P; Stoyneva, V1
Aldawsari, HM; Badr-Eldin, SM; Labib, GS1
Barbareschi, M; De Micheli, P; Raia, DD; Schianchi, R; Veraldi, S1
Inbasekaran, S; Jayakumari, LS; Meenakshi, S; Pandian, K1
Ganji, F; Pakzad, Y1
Aboul-Einien, MH; El-Mahrouk, GM; Makhlouf, AI1
Bansal, M; Khan, G; Mishra, B; Nath, G; Patel, RR; Yadav, SK1
Bories, C; Bouchemal, K; Loiseau, PM; Malli, S; Ponchel, G; Pradines, B1
Baumgartner, S; Kocbek, P; Kristl, J; Potrč, T; Zupančič, Š1
Karimi, AR; Nikravesh, G; Tarighatjoo, M1
Chang, PC; Feng, F; Lin, JH; Wang, CH; Yu, MC1
Bernkop-Schnürch, A; Fodor, B; Lupo, N; Matuszczak, B; Muhammad, I; Yaqoob, M1
Bauab, TM; Calixto, GMF; Chorilli, M; Ramos, MADS; Victorelli, FD1
Bories, C; Bouchemal, K; Bourge, M; Loiseau, PM; Malli, S1
Bao, C; Chen, Y; Huang, L; Liu, J; Wang, X; Xiao, Y1
Chen, SM; Mutharani, B; Ranganathan, P; Sireesha, P1
Allam, AF; Farag, HF; Fawzy Hussein Mogahed, NM; Hagras, NA; Osman, MM; Shalaby, TI; Shehab, AY; Tolba, MM1
Casula, L; Fadda, AM; Kocbek, P; Kristl, J; Lapanje, A; Luštrik, M; Rijavec, T; Zupančič, Š1
Almdal, K; Boisen, A; Bose Goswami, S; Demarchi, D; Marsich, E; Sacco, P; Siccardi, G; Tentor, F1
Asgari, E; Sheikhmohammadi, A; Yeganeh, J1
Bazzucchi, V; Cirri, M; Maestrelli, F; Mura, P; Scuota, S1
Binesh, N; Farhadian, N; Mohammadzadeh, A1
Bahrami, SH; Bashari, A; Hemmatinejad, N; Rohani Shirvan, A1
Emami, N; Farhadian, M; Ghiasi, F; Solaimany Nazar, AR; Tangestaninejad, S1
Li, X; Lu, S; Pan, Y; Shao, T; Wang, D; Wu, Z; Yan, M; Zhou, Q1
Araújo, A; Leão, P; Martins, A; Neves, NM; Oliveira, A; Reis, RL; Rodrigues, LC; Silva, CS1
Sadeghi, M; Shabani-Nooshabadi, M1

Trials

1 trial(s) available for metronidazole and chitosan

ArticleYear
Application of chitosan gel in the treatment of chronic periodontitis.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2007, Volume: 80, Issue:2

    Topics: Adult; Anti-Infective Agents, Local; Biocompatible Materials; Chitosan; Chronic Disease; Dental Materials; Drug Carriers; Female; Gels; Humans; Male; Materials Testing; Metronidazole; Middle Aged; Periodontitis

2007

Other Studies

39 other study(ies) available for metronidazole and chitosan

ArticleYear
Preparation and characterization of freeze-dried chitosan-poly(ethylene oxide) hydrogels for site-specific antibiotic delivery in the stomach.
    Pharmaceutical research, 1996, Volume: 13, Issue:4

    Topics: Amoxicillin; Antitrichomonal Agents; Biocompatible Materials; Chitin; Chitosan; Drug Delivery Systems; Freeze Drying; Gastric Juice; Gastric Mucosa; Gels; Humans; Hydrogen-Ion Concentration; Intestinal Secretions; Metronidazole; Microscopy, Electron, Scanning; Penicillins; Polyethylene Glycols; Surface-Active Agents

1996
Evaluation of the factors influencing stomach-specific delivery of antibacterial agents for Helicobacter pylori infection.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:6

    Topics: Amoxicillin; Chitin; Chitosan; Drug Stability; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Metronidazole; Microspheres; Permeability

1999
Use of floating alginate gel beads for stomach-specific drug delivery.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2000, Volume: 50, Issue:2

    Topics: Alginates; Animals; Anti-Infective Agents; Chitin; Chitosan; Drug Delivery Systems; Gastric Mucosa; Gels; Glucuronic Acid; Guinea Pigs; Hexuronic Acids; Male; Metronidazole; Solubility

2000
Chitosan and sodium alginate-based bioadhesive vaginal tablets.
    AAPS pharmSci, 2002, Volume: 4, Issue:4

    Topics: Alginates; Anti-Infective Agents; Chemistry, Pharmaceutical; Chitin; Chitosan; Delayed-Action Preparations; Female; Glucuronic Acid; Hexuronic Acids; Humans; Metronidazole; Vaginal Creams, Foams, and Jellies

2002
Micromatricial metronidazole benzoate film as a local mucoadhesive delivery system for treatment of periodontal diseases.
    AAPS PharmSciTech, 2007, Sep-14, Volume: 8, Issue:3

    Topics: Adhesiveness; Anti-Infective Agents; Chitosan; Delayed-Action Preparations; Humans; Metronidazole; Molecular Weight; Mouth Mucosa; Particle Size; Periodontal Diseases; Polyesters; Saliva; Solubility; Wettability

2007
Chitosan inserts for periodontitis: influence of drug loading, plasticizer and crosslinking on in vitro metronidazole release.
    Acta pharmaceutica (Zagreb, Croatia), 2007, Volume: 57, Issue:4

    Topics: Animals; Anti-Infective Agents; Chemistry, Pharmaceutical; Chitosan; Cross-Linking Reagents; Drug Carriers; Drug Compounding; Drug Implants; Glutaral; Humans; Kinetics; Metronidazole; Periodontitis; Plasticizers; Propylene Glycol; Solubility

2007
FG90 chitosan as a new polymer for metronidazole mucoadhesive tablets for vaginal administration.
    International journal of pharmaceutics, 2009, Jul-30, Volume: 377, Issue:1-2

    Topics: Acrylic Resins; Administration, Intravaginal; Anti-Bacterial Agents; Chitosan; Drug Carriers; Drug Compounding; Metronidazole; Models, Statistical; Povidone; Tissue Adhesives; Vaginal Creams, Foams, and Jellies

2009
Chitosan membranes modified by contact with poly(acrylic acid).
    Carbohydrate research, 2009, Sep-08, Volume: 344, Issue:13

    Topics: Absorption; Acrylic Resins; Chitosan; Electrolytes; Membranes, Artificial; Metronidazole; Microscopy, Electron, Scanning; Permeability; Spectroscopy, Fourier Transform Infrared; Sulfamerazine; Temperature; Water

2009
Bioadhesive controlled metronidazole release matrix based on chitosan and xanthan gum.
    Marine drugs, 2010, May-25, Volume: 8, Issue:5

    Topics: Adhesiveness; Animals; Biological Availability; Chitosan; Delayed-Action Preparations; Duodenum; Humans; Metronidazole; Polymers; Polysaccharides, Bacterial; Sheep; Stomach

2010
Development and in vitro evaluation of thiolated chitosan--Poly(methacrylic acid) nanoparticles as a local mucoadhesive delivery system.
    International journal of biological macromolecules, 2011, Apr-01, Volume: 48, Issue:3

    Topics: Adhesiveness; Chitosan; Differential Thermal Analysis; Drug Delivery Systems; Humans; Metronidazole; Mouth Mucosa; Nanoparticles; Polymethacrylic Acids

2011
Development and in vitro evaluation of coated pellets containing chitosan to potential colonic drug delivery.
    Carbohydrate polymers, 2013, Jan-02, Volume: 91, Issue:1

    Topics: Animals; Chitosan; Colon; Drug Carriers; Intestinal Absorption; Kinetics; Male; Metronidazole; Permeability; Polyvinyls; Rats; Rats, Wistar

2013
Evaluation of cross-linked chitosan microparticles containing metronidazole for periodontitis treatment.
    Materials science & engineering. C, Materials for biological applications, 2013, Apr-01, Volume: 33, Issue:3

    Topics: Chemistry, Pharmaceutical; Chitosan; Cross-Linking Reagents; Emulsions; Glutaral; Hydrogels; Metronidazole; Microscopy, Electron, Scanning; Microspheres; Periodontitis

2013
Stimuli sensitive super-macroporous cryogels based on photo-crosslinked 2-hydroxyethylcellulose and chitosan.
    Carbohydrate polymers, 2014, Volume: 99

    Topics: Acrylamides; Cellulose; Chitosan; Cross-Linking Reagents; Cryogels; Drug Carriers; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Metronidazole; Porosity; Rheology; Ultraviolet Rays; Water

2014
Metronidazole and Pentoxifylline films for the local treatment of chronic periodontal pockets: preparation, in vitro evaluation and clinical assessment.
    Expert opinion on drug delivery, 2014, Volume: 11, Issue:6

    Topics: Acrylates; Adult; Anti-Infective Agents; Calorimetry, Differential Scanning; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Female; Humans; Hydrogen-Ion Concentration; Hypromellose Derivatives; Male; Methylcellulose; Metronidazole; Microscopy, Electron, Scanning; Middle Aged; Pentoxifylline; Periodontal Pocket; Platelet Aggregation Inhibitors

2014
Treatment of symptoms of erythemato-telangiectatic rosacea with topical potassium azeloyl diglycinate and hydroxypropyl chitosan: Results of a sponsor-free, multicenter, open study.
    The Journal of dermatological treatment, 2015, Volume: 26, Issue:2

    Topics: Administration, Cutaneous; Adult; Aged; Chitosan; Dermatologic Agents; Female; Glycine; Humans; Male; Metronidazole; Middle Aged; Rosacea

2015
Enhanced amperometric detection of metronidazole in drug formulations and urine samples based on chitosan protected tetrasulfonated copper phthalocyanine thin-film modified glassy carbon electrode.
    Materials science & engineering. C, Materials for biological applications, 2016, Volume: 59

    Topics: Carbon; Chitosan; Copper; Electrodes; Humans; Indoles; Metronidazole

2016
Thermosensitive hydrogel for periodontal application: in vitro drug release, antibacterial activity and toxicity evaluation.
    Journal of biomaterials applications, 2016, Volume: 30, Issue:7

    Topics: Anti-Bacterial Agents; Chitosan; Drug Carriers; Gelatin; Glycerophosphates; HEK293 Cells; Humans; Hydrogels; Hydrogen-Ion Concentration; Metronidazole; Microscopy, Electron, Scanning; Molecular Weight; Periodontics; Phosphates; Rheology; Solutions; Temperature; Vancomycin

2016
Design, Optimization, and Evaluation of a Novel Metronidazole-Loaded Gastro-Retentive pH-Sensitive Hydrogel.
    AAPS PharmSciTech, 2016, Volume: 17, Issue:6

    Topics: Animals; Chemistry, Pharmaceutical; Chitosan; Dogs; Drug Carriers; Drug Delivery Systems; Drug Liberation; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogen-Ion Concentration; Metronidazole; Polyphosphates

2016
Development and Evaluation of Biodegradable Chitosan Films of Metronidazole and Levofloxacin for the Management of Periodontitis.
    AAPS PharmSciTech, 2016, Volume: 17, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Liberation; Escherichia coli; Excipients; Glutaral; Humans; Levofloxacin; Metronidazole; Middle Aged; Periodontal Pocket; Periodontitis; Plasticizers; Single-Blind Method; Staphylococcus aureus; Young Adult

2016
In situ forming pluronic® F127/chitosan hydrogel limits metronidazole transmucosal absorption.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2017, Volume: 112

    Topics: Animals; Antiprotozoal Agents; Chitosan; Female; Hydrogels; Metronidazole; Mucous Membrane; Permeability; Poloxamer; Swine; Vagina

2017
Formulation and evaluation of chitosan/polyethylene oxide nanofibers loaded with metronidazole for local infections.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Dec-01, Volume: 95

    Topics: Anti-Infective Agents; Calorimetry, Differential Scanning; Chitosan; Drug Delivery Systems; Metronidazole; Microscopy, Electron, Scanning; Nanofibers; Polyethylene Glycols

2016
1,3,5-Triazine-2,4,6-tribenzaldehyde derivative as a new crosslinking agent for synthesis of pH-thermo dual responsive chitosan hydrogels and their nanocomposites: Swelling properties and drug release behavior.
    International journal of biological macromolecules, 2017, Volume: 105, Issue:Pt 1

    Topics: Anti-Bacterial Agents; Benzaldehydes; Chitosan; Drug Carriers; Drug Liberation; Hydrogels; Hydrogen-Ion Concentration; Metronidazole; Nanocomposites; Nanotechnology; Temperature

2017
Modulation of periodontitis progression using pH-responsive nanosphere encapsulating metronidazole or N-phenacylthialzolium bromide.
    Journal of periodontal research, 2018, Volume: 53, Issue:1

    Topics: Animals; Anti-Infective Agents; Chitosan; Disease Models, Animal; Disease Progression; Lactic Acid; Metronidazole; Nanospheres; Periodontitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Thiazoles

2018
Entirely S-protected chitosan: A promising mucoadhesive excipient for metronidazole vaginal tablets.
    Acta biomaterialia, 2017, Volume: 64

    Topics: Animals; Chitosan; Female; Metronidazole; Swine; Vagina; Vaginal Creams, Foams, and Jellies

2017
Metronidazole-Loaded Polyethyleneimine and Chitosan-Based Liquid Crystalline System for Treatment of Staphylococcal Skin Infections.
    Journal of biomedical nanotechnology, 2018, Jan-01, Volume: 14, Issue:1

    Topics: Anti-Infective Agents; Chitosan; Humans; Liquid Crystals; Metronidazole; Polyethyleneimine; Skin; Staphylococcal Skin Infections

2018
Surface-dependent endocytosis of poly(isobutylcyanoacrylate) nanoparticles by Trichomonas vaginalis.
    International journal of pharmaceutics, 2018, Sep-05, Volume: 548, Issue:1

    Topics: Antiprotozoal Agents; Cell Membrane; Chitosan; Cyanoacrylates; Enbucrilate; Endocytosis; Metronidazole; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Poloxamer; Trichomonas vaginalis

2018
Glucose-sensitive delivery of metronidazole by using a photo-crosslinked chitosan hydrogel film to inhibit Porphyromonas gingivalis proliferation.
    International journal of biological macromolecules, 2019, Feb-01, Volume: 122

    Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Cell Proliferation; Chitosan; Drug Carriers; Drug Liberation; Enzymes, Immobilized; Glucose; Glucose Oxidase; Materials Testing; Methylgalactosides; Metronidazole; Mice; Microbial Sensitivity Tests; Photochemical Processes; Porphyromonas gingivalis

2019
Biocompatible chitosan-pectin polyelectrolyte complex for simultaneous electrochemical determination of metronidazole and metribuzin.
    Carbohydrate polymers, 2019, Jun-15, Volume: 214

    Topics: Anti-Bacterial Agents; Biocompatible Materials; Carbon; Chitosan; Electrochemical Techniques; Electrodes; Green Chemistry Technology; Herbicides; Humans; Limit of Detection; Metronidazole; Molecular Weight; Oxidation-Reduction; Pectins; Polyelectrolytes; Reproducibility of Results; Triazines; Viscosity

2019
Successful treatment of acute experimental toxoplasmosis by spiramycin-loaded chitosan nanoparticles.
    Experimental parasitology, 2019, Volume: 204

    Topics: Acute Disease; Animals; Ascitic Fluid; Biocompatible Materials; Blood-Brain Barrier; Brain; Chitosan; Coccidiostats; Drug Combinations; Drug Delivery Systems; Kaplan-Meier Estimate; Liver; Male; Metronidazole; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Pilot Projects; Spiramycin; Spleen; Survival Rate; Tablets; Toxoplasma; Toxoplasmosis, Animal

2019
Sustained release of antimicrobials from double-layer nanofiber mats for local treatment of periodontal disease, evaluated using a new micro flow-through apparatus.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 12-28, Volume: 316

    Topics: Anti-Bacterial Agents; Chitosan; Ciprofloxacin; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Metronidazole; Microbial Sensitivity Tests; Nanofibers; Periodontal Diseases; Polyesters; Polyethylene Glycols; Solubility

2019
Long lasting mucoadhesive membrane based on alginate and chitosan for intravaginal drug delivery.
    Journal of materials science. Materials in medicine, 2020, Feb-14, Volume: 31, Issue:3

    Topics: Adhesiveness; Administration, Intravaginal; Alginates; Anti-Bacterial Agents; Biocompatible Materials; Cervix Uteri; Chitosan; Compressive Strength; Drug Delivery Systems; Epithelial Cells; Female; Gardnerella vaginalis; Humans; Hydrogels; Kinetics; Membranes, Artificial; Metronidazole; Microscopy, Confocal; Staphylococcus aureus; Stress, Mechanical; Vagina; Vaginosis, Bacterial

2020
Application of the Fe
    International journal of biological macromolecules, 2020, Dec-01, Volume: 164

    Topics: Adsorption; Chitosan; Ferric Compounds; Hydrogen-Ion Concentration; Kinetics; Magnetite Nanoparticles; Metronidazole; Temperature; Thermodynamics; Wastewater; Water Pollutants, Chemical; Water Purification

2020
Development and microbiological evaluation of chitosan and chitosan-alginate microspheres for vaginal administration of metronidazole.
    International journal of pharmaceutics, 2021, Apr-01, Volume: 598

    Topics: Administration, Intravaginal; Alginates; Chitosan; Female; Humans; Metronidazole; Microspheres

2021
Enhanced antibacterial activity of uniform and stable chitosan nanoparticles containing metronidazole against anaerobic bacterium of Bacteroides fragilis.
    Colloids and surfaces. B, Biointerfaces, 2021, Volume: 202

    Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteroides fragilis; Base Composition; Chitosan; Drug Carriers; Drug Liberation; Metronidazole; Nanoparticles; Particle Size; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA

2021
Fabrication of multifunctional mucoadhesive buccal patch for drug delivery applications.
    Journal of biomedical materials research. Part A, 2021, Volume: 109, Issue:12

    Topics: Administration, Buccal; Animals; Cheek; Chitosan; Cross-Linking Reagents; Drug Delivery Systems; Ibuprofen; Iridoids; Metronidazole; Mice; Microscopy, Electron, Scanning; Nanotubes; Phenylalanine; Polyvinyl Alcohol; Streptococcus mutans; Tensile Strength; Tissue Adhesives

2021
Synthesis of aqueous media stable MIL101-OH/chitosan for diphenhydramine and metronidazole adsorption.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:16

    Topics: Adsorption; Chitosan; Diphenhydramine; Hydrogen-Ion Concentration; Kinetics; Metronidazole; Water Pollutants, Chemical

2022
Chitosan-CaP microflowers and metronidazole loaded calcium alginate sponges with enhanced antibacterial, hemostatic and osteogenic properties for the prevention of dry socket after tooth removal.
    International journal of biological macromolecules, 2022, Jul-01, Volume: 212

    Topics: Alginates; Anti-Bacterial Agents; Chitosan; Dry Socket; Escherichia coli; Hemostatics; Humans; Metronidazole; Osteogenesis; Porosity; Staphylococcus aureus; Tooth Extraction

2022
Metronidazole Delivery Nanosystem Able To Reduce the Pathogenicity of Bacteria in Colorectal Infection.
    Biomacromolecules, 2022, 06-13, Volume: 23, Issue:6

    Topics: Anti-Bacterial Agents; Bacteria; Chitosan; Colorectal Neoplasms; Drug Delivery Systems; Escherichia coli; Humans; Metronidazole; Nanoparticles; Virulence

2022
Use of a nano-porous gold film electrode modified with chitosan / polypyrrole for electrochemical determination of metronidazole in the Presence of Acetaminophen.
    Chemosphere, 2022, Volume: 307, Issue:Pt 1

    Topics: Acetaminophen; Chitosan; Electrochemical Techniques; Electrodes; Gold; Metronidazole; Polymers; Pyrroles

2022