metronidazole and benzonidazole

metronidazole has been researched along with benzonidazole in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19903 (14.29)18.7374
1990's0 (0.00)18.2507
2000's1 (4.76)29.6817
2010's17 (80.95)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cedillo-Rivera, R; Hernández-Núñez, E; Moo-Puc, R; Nava-Zuazo, C; Navarrete-Vazquez, G; Reyes-Martínez, R; Tlahuext, H; Torres-Gómez, H1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fairlamb, AH; Oza, SL; Patterson, S; Read, KD; Sokolova, AY; Wyllie, S1
Cedillo-Rivera, R; Chan-Bacab, MJ; Estrada-Soto, S; Guerrero-Alvarez, J; León-Rivera, I; Mirón-López, G; Molina-Salinas, GM; Moo-Puc, R; Nava-Zuazo, C; Navarrete-Vazquez, G; Said-Fernández, S1
Argotte-Ramos, R; Cedillo-Rivera, R; Chan-Bacab, MJ; Chávez-Silva, F; Hernández-Nuñez, E; Moo-Puc, R; Navarrete-Vazquez, G; Rodríguez-Gutiérrez, Mdel C1
Brun, R; Huang, TL; Kaiser, M; Mayence, A; Vanden Eynde, JJ; Yarlett, N1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chan-Bacab, MJ; Chávez-Silva, F; Díaz-Coutiño, D; Hernández-Núñez, E; Moo-Puc, R; Moreno-Díaz, H; Nava-Zuazo, C; Navarrete-Vázquez, G; Ortega-Morales, BO1
Battistuzzi, G; Giannini, G1
Battistuzzi, G; Giannini, G; Vignola, D1
Arán, VJ; Cumella, J; da Silva, PB; Escario, JA; Fonseca-Berzal, C; Gómez-Barrio, A; Ibáñez-Escribano, A; Jagerovic, N; Morales, P; Nogal-Ruiz, JJ; Reviriego, F; Soeiro, Mde N1
Ang, CW; Blaskovich, MAT; Cooper, MA; Jarrad, AM1
Argüello-Garcia, R; Barbosa-Cabrera, E; Chan-Bacab, MJ; Colín-Lozano, B; Hernández-Núñez, E; León-Rivera, I; López-Guerrero, V; Moo-Puc, R; Navarrete-Vázquez, G; Ortega-Morales, BO; Scior, T1
Bloomer, WD; Kaiser, M; Papadopoulou, MV; Rosenzweig, HS1
Azas, N; Basmaciyan, L; Belle Mbou, V; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, É; Casanova, M; Castera-Ducros, C; Cohen, A; Courtioux, B; Fairlamb, AH; Fersing, C; Hutter, S; Laget, M; Milne, R; Pedron, J; Piednoel, M; Primas, N; Rathelot, P; Since, M; Sournia-Saquet, A; Valentin, A; Vanelle, P; Verhaeghe, P; Wyllie, S1
Docampo, R; Moreno, SN1
Dische, S1
Moore, DE1
Bahia, MT; Batista, DGJ; Batista, MM; Cardoso-Santos, C; D'Almeida-Melo, I; Da Silva, CF; Da Silva, PB; De Araújo, JS; Demarque, KC; Oliveira, GM; Peres, RB; Simões-Silva, MR; Soeiro, MNC1
Arán-Redó, VJ; Barigye, SJ; Escario, JA; García-Jacas, CR; Gómez-Barrio, A; Ibáñez-Escribano, A; Machado-Tugores, Y; Marrero-Ponce, Y; Meneses-Marcel, A; Nogal-Ruiz, JJ; Terán, E1
Hussar, DA1

Reviews

3 review(s) available for metronidazole and benzonidazole

ArticleYear
Nitroimidazoles: Molecular Fireworks That Combat a Broad Spectrum of Infectious Diseases.
    Journal of medicinal chemistry, 2017, 09-28, Volume: 60, Issue:18

    Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Communicable Diseases; Humans; Nitroimidazoles; Parasitic Diseases

2017
Free radical metabolism of antiparasitic agents.
    Federation proceedings, 1986, Volume: 45, Issue:10

    Topics: Animals; Chemical Phenomena; Chemistry; Free Radicals; Hydrogen Peroxide; Macromolecular Substances; Metronidazole; Nifurtimox; Niridazole; Nitro Compounds; Nitroimidazoles; Oxidation-Reduction; Parasitic Diseases; Schistosoma mansoni; Superoxides; Tritrichomonas; Trypanosoma cruzi

1986
Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2

    Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nimorazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents

1985

Trials

1 trial(s) available for metronidazole and benzonidazole

ArticleYear
Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1985, Volume: 3, Issue:2

    Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Etanidazole; Humans; Metronidazole; Misonidazole; Neoplasms; Nimorazole; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents

1985

Other Studies

18 other study(ies) available for metronidazole and benzonidazole

ArticleYear
Synthesis and in vitro trichomonicidal, giardicidal and amebicidal activity of N-acetamide(sulfonamide)-2-methyl-4-nitro-1H-imidazoles.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:7

    Topics: Animals; Antiprotozoal Agents; Cell Line; Computational Biology; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Entamoeba histolytica; Giardia lamblia; Imidazoles; Nitroimidazoles; Trichomonas vaginalis

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Cross-resistance to nitro drugs and implications for treatment of human African trypanosomiasis.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Animals; Cell Line; Drug Resistance; Eflornithine; Humans; Mice; Nifurtimox; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2010
Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N-{2-[(7-chloroquinolin-4-yl)amino]ethyl}ureas.
    Bioorganic & medicinal chemistry, 2010, Sep-01, Volume: 18, Issue:17

    Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Drug Design; Giardia lamblia; Humans; Leishmania mexicana; Mycobacterium tuberculosis; Quinolines; Structure-Activity Relationship; Urea

2010
Synthesis of benzologues of Nitazoxanide and Tizoxanide: a comparative study of their in vitro broad-spectrum antiprotozoal activity.
    Bioorganic & medicinal chemistry letters, 2011, May-15, Volume: 21, Issue:10

    Topics: Antiprotozoal Agents; Giardia; Molecular Structure; Nitro Compounds; Plasmodium; Thiazoles; Trichomonas vaginalis

2011
Bis(oxyphenylene)benzimidazoles: a novel class of anti-Plasmodium falciparum agents.
    Bioorganic & medicinal chemistry, 2011, Dec-15, Volume: 19, Issue:24

    Topics: Animals; Antimalarials; Benzimidazoles; Cell Line; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
2-acylamino-5-nitro-1,3-thiazoles: preparation and in vitro bioevaluation against four neglected protozoan parasites.
    Bioorganic & medicinal chemistry, 2014, Mar-01, Volume: 22, Issue:5

    Topics: Animals; Antiprotozoal Agents; Drug Design; Humans; Protozoan Infections; Thiazoles

2014
Exploring in vitro and in vivo Hsp90 inhibitors activity against human protozoan parasites.
    Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3

    Topics: Animals; Antiprotozoal Agents; Cell Line, Tumor; Disease Models, Animal; HSP90 Heat-Shock Proteins; Humans; Mice; Parasitemia; Plasmodium falciparum; Protein Binding; Rats; Triazoles; Trypanosoma brucei rhodesiense

2015
Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite.
    Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3

    Topics: Animals; Antimalarials; Cell Line, Tumor; Dipeptides; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Malaria; Mice; Parasites; Plasmodium falciparum; Protein Isoforms

2015
Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles.
    European journal of medicinal chemistry, 2016, Jun-10, Volume: 115

    Topics: Animals; Chagas Disease; Indazoles; Structure-Activity Relationship; Trichomonas; Trypanosoma cruzi

2016
Synthesis, in vitro and in vivo giardicidal activity of nitrothiazole-NSAID chimeras displaying broad antiprotozoal spectrum.
    Bioorganic & medicinal chemistry letters, 2017, 08-01, Volume: 27, Issue:15

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiprotozoal Agents; Drug Design; Female; Giardia lamblia; Giardiasis; Humans; Leishmania; Mice; Nitro Compounds; Protozoan Infections; Thiazoles; Trichomonas vaginalis; Trypanosoma cruzi

2017
The antitrypanosomal and antitubercular activity of some nitro(triazole/imidazole)-based aromatic amines.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Amines; Antitubercular Agents; Dose-Response Relationship, Drug; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Parasitic Sensitivity Tests; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi

2017
Nongenotoxic 3-Nitroimidazo[1,2-
    ACS medicinal chemistry letters, 2019, Jan-10, Volume: 10, Issue:1

    Topics:

2019
Reactions of nitroimidazoles with free radicals--enhancement of reaction by u.v. irradiation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 47, Issue:5

    Topics: Acrylic Resins; Free Radicals; Metronidazole; Misonidazole; Mutagens; Nitroimidazoles; Ornidazole; Potassium; Potassium Compounds; Radiation-Sensitizing Agents; Sulfates; Ultraviolet Rays

1985
Drug repurposing strategy against Trypanosoma cruzi infection: In vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy.
    Biochemical pharmacology, 2017, 12-01, Volume: 145

    Topics: Animals; Antiprotozoal Agents; Cells, Cultured; Chagas Disease; Drug Therapy, Combination; Metronidazole; Mice; Molecular Structure; Myocytes, Cardiac; Nitroimidazoles; Trypanosoma cruzi

2017
Drug repositioning for novel antitrichomonas from known antiprotozoan drugs using hierarchical screening.
    Future medicinal chemistry, 2018, 04-01, Volume: 10, Issue:8

    Topics: Animals; Antiprotozoal Agents; Discriminant Analysis; Drug Repositioning; Drug Resistance; Female; Humans; Metronidazole; Mice; Nitroimidazoles; Trichomonas Infections; Trichomonas vaginalis; Trichomonas Vaginitis

2018
New Drugs 2018, part 3.
    Nursing, 2018, Volume: 48, Issue:10

    Topics: Acetates; Boronic Acids; Drug Approval; Drug Combinations; Fluoroquinolones; Humans; Meropenem; Metronidazole; Nitroimidazoles; Parathyroid Hormone-Related Protein; Peptides; Prostaglandins F, Synthetic; Quinazolines; Thienamycins; United States; United States Food and Drug Administration

2018